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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
MDA5 Recombinant Rabbit Monoclonal Antibody (33H12L34)
catalog :
700360
quantity :
100 ug
price :
US 471.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
33H12L34
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, RNA immunoprecipitation
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig 10g
Nikolic J, Civas A, Lama Z, Lagaudrière Gesbert C, Blondel D. Rabies Virus Infection Induces the Formation of Stress Granules Closely Connected to the Viral Factories. PLoS Pathog. 2016;12:e1005942 pubmed publisher
  • western blot; human
Israelow B, Narbus C, Sourisseau M, Evans M. HepG2 cells mount an effective antiviral interferon-lambda based innate immune response to hepatitis C virus infection. Hepatology. 2014;60:1170-9 pubmed publisher
Jiyarom B, Giannakopoulos S, Strange D, Panova N, Gale M, Verma S. RIG-I and MDA5 are modulated by bone morphogenetic protein (BMP6) and are essential for restricting Zika virus infection in human Sertoli cells. Front Microbiol. 2022;13:1062499 pubmed publisher
Elsaid A, Agrawal S, Agrawal A, Ghoneum M. Dietary Supplementation with Biobran/MGN-3 Increases Innate Resistance and Reduces the Incidence of Influenza-like Illnesses in Elderly Subjects: A Randomized, Double-Blind, Placebo-Controlled Pilot Clinical Trial. Nutrients. 2021;13: pubmed publisher
Zhou X, Backman L, Danielson P. Activation of NF-κB signaling via cytosolic mitochondrial RNA sensing in kerotocytes with mitochondrial DNA common deletion. Sci Rep. 2021;11:7360 pubmed publisher
Shao W, Earley L, Chai Z, Chen X, Sun J, He T, et al. Double-stranded RNA innate immune response activation from long-term adeno-associated virus vector transduction. JCI Insight. 2018;3: pubmed publisher
product information
Product Type :
Antibody
Product Name :
MDA5 Recombinant Rabbit Monoclonal Antibody (33H12L34)
Catalog # :
700360
Quantity :
100 ug
Price :
US 471.00
Clonality :
Recombinant Monoclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
Immunocytochemistry: 4-6 ug/mL, Immunohistochemistry (Paraffin): 1:20, Immunoprecipitation: Assay-dependent, RNA Immunoprecipitation: Assay-dependent, Western Blot: 4-6 ug/mL
Species :
Human, Mouse
Clone :
33H12L34
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation.
Immunogen :
A recombinant protein corresponding to amino acids 883-1025 of Q9BYX4.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 4-6 ug/mL, Immunohistochemistry (Paraffin): 1:20, Immunoprecipitation: Assay-dependent, RNA Immunoprecipitation: Assay-dependent, Western Blot: 4-6 ug/mL
Aliases :
9130009C22Rik; AGS7; CADM-140 autoantigen; Clinically amyopathic dermatomyositis autoantigen 140 kDa; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; helicard; Helicase with 2 CARD domains; Hlcd; IDDM19; IFIH1; interferon induced with helicase C domain 1; interferon induced with helicase C domain protein 1; interferon induced, with helicase C domain 1; interferon-induced helicase C domain-containing protein 1; Interferon-induced with helicase C domain protein 1; MDA5; MDA-5; melanoma differentiation associated protein-5; melanoma differentiation-associated gene 5; melanoma differentiation-associated protein 5; MGC133047; Murabutide down-regulated protein; RGD1560496; RH116; RIG-I-like receptor 2; RLR-2; RNA helicase-DEAD box protein 116; SGMRT1
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA