Connexin 30 Recombinant Rabbit Monoclonal Antibody (16H9L8) | Invitrogen 700258 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Connexin 30 Recombinant Rabbit Monoclonal Antibody (16H9L8)

catalog :

700258

quantity :

100 ug

price :

US 450.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

16H9L8

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; loading ...; fig 1d	Sun L, Gao D, Chen J, Hou S, Li Y, Huang Y, et al. Failure Of Hearing Acquisition in Mice With Reduced Expression of Connexin 26 Correlates With the Abnormal Phasing of Apoptosis Relative to Autophagy and Defective ATP-Dependent Ca2+ Signaling in Kölliker's Organ. Front Cell Neurosci. 2022;16:816079 pubmed publisher
immunohistochemistry; mouse; 1:500; fig 1a	Augustin V, Bold C, Wadle S, Langer J, Jabs R, Philippot C, et al. Functional anisotropic panglial networks in the lateral superior olive. Glia. 2016;64:1892-911 pubmed publisher
immunoprecipitation; mouse; fig 10	Dianati E, Poiraud J, Weber Ouellette A, Plante I. Connexins, E-cadherin, Claudin-7 and ?-catenin transiently form junctional nexuses during the post-natal mammary gland development. Dev Biol. 2016;416:52-68 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:200; fig 2 western blot; mouse; 1:500; fig 2	Almad A, Doreswamy A, Gross S, Richard J, Huo Y, Haughey N, et al. Connexin 43 in astrocytes contributes to motor neuron toxicity in amyotrophic lateral sclerosis. Glia. 2016;64:1154-69 pubmed publisher
	Eitelmann S, Petersilie L, Rose C, Stephan J. Altered Gap Junction Network Topography in Mouse Models for Human Hereditary Deafness. Int J Mol Sci. 2020;21: pubmed publisher
	Popov A, Denisov P, Bychkov M, Brazhe A, Lyukmanova E, Shenkarev Z, et al. Caloric restriction triggers morphofunctional remodeling of astrocytes and enhances synaptic plasticity in the mouse hippocampus. Cell Death Dis. 2020;11:208 pubmed publisher
	Wadle S, Augustin V, Langer J, Jabs R, Philippot C, Weingarten D, et al. Anisotropic Panglial Coupling Reflects Tonotopic Organization in the Inferior Colliculus. Front Cell Neurosci. 2018;12:431 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Connexin 30 Recombinant Rabbit Monoclonal Antibody (16H9L8)

Catalog # :

700258

Quantity :

100 ug

Price :

US 450.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 0.5-1 ug/mL, Western Blot: 1-3 ug/mL

Species :

Human, Mouse

Clone :

16H9L8

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia.

Immunogen :

A peptide corresponding to amino acids 241-261 of P70689.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 0.5-1 ug/mL, Western Blot: 1-3 ug/mL

Aliases :

AA958971; connexin 30; connexin-30; CX30; Cxn-30; D14Bwg0506e; DFNA3; DFNA3B; DFNB1B; ECTD2; ectodermal dysplasia 2, hidrotic (Clouston syndrome); ED2; EDH; Gap junction beta-6 protein; gap junction membrane channel protein beta 6; gap junction protein beta 6; gap junction protein, beta 6; gap junction protein, beta 6 (connexin 30); gap junction protein, beta 6, 30kDa; Gjb6; HED; HED2

more info or order :

Invitrogen product webpage