Phospho-4EBP1 (Thr37) Recombinant Rabbit Monoclonal Antibody (52H37L2)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-4EBP1 (Thr37) Recombinant Rabbit Monoclonal Antibody (52H37L2)

catalog :

700238

quantity :

100 ug

price :

US 520.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

52H37L2

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 2

Reference
Danese A, Patergnani S, Maresca A, Peron C, Raimondi A, Caporali L, et al. Pathological mitophagy disrupts mitochondrial homeostasis in Leber's hereditary optic neuropathy. Cell Rep. 2022;40:111124 pubmed publisher
An Y, Liu H, Zhou Z, Wang J, Jiang G, Li Z, et al. Sinoporphyrin sodium is a promising sensitizer for photodynamic and sonodynamic therapy in glioma. Oncol Rep. 2020;44:1596-1604 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Phospho-4EBP1 (Thr37) Recombinant Rabbit Monoclonal Antibody (52H37L2)

Catalog # :

700238

Quantity :

100 ug

Price :

US 520.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

ELISA: 1-5 ug/mL, Flow Cytometry: 1-4 ug/1x10^6 cells, Immunocytochemistry: 2-4 ug, Immunohistochemistry (Paraffin): 5-6 ug/mL, Western Blot: 1-3 ug/mL

Species :

Human

Clone :

52H37L2

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Immunogen :

A peptide corresponding to amino acids 31-41 of Q13541.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1-5 ug/mL, Flow Cytometry: 1-4 ug/1x10^6 cells, Immunocytochemistry: 2-4 ug, Immunohistochemistry (Paraffin): 5-6 ug/mL, Western Blot: 1-3 ug/mL

Aliases :

4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1