product summary
Loading...
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Caspase 3 Recombinant Rabbit Monoclonal Antibody (9H19L2)
catalog :
700182
quantity :
100 µg
price :
US 425.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
9H19L2
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
Invitrogen product webpage
citations: 21
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 7a
Sharapov M, Goncharov R, Filkov G, Trofimenko A, Boyarintsev V, Novoselov V. Comparative Study of Protective Action of Exogenous 2-Cys Peroxiredoxins (Prx1 and Prx2) Under Renal Ischemia-Reperfusion Injury. Antioxidants (Basel). 2020;9: pubmed publisher
  • immunocytochemistry; human; fig 5
Ghorai A, Sarma A, Chowdhury P, Ghosh U. PARP-1 depletion in combination with carbon ion exposure significantly reduces MMPs activity and overall increases TIMPs expression in cultured HeLa cells. Radiat Oncol. 2016;11:126 pubmed
  • western blot; human; 1:500; loading ...; fig 3h
Ranjan K, Pathak C. Expression of FADD and cFLIPL balances mitochondrial integrity and redox signaling to substantiate apoptotic cell death. Mol Cell Biochem. 2016;422:135-150 pubmed
  • western blot; human; fig 4
Kant R, Yen C, Lu C, Lin Y, Li J, Chen Y. Identification of 1,2,3,4,6-Penta-O-galloyl-?-d-glucopyranoside as a Glycine N-Methyltransferase Enhancer by High-Throughput Screening of Natural Products Inhibits Hepatocellular Carcinoma. Int J Mol Sci. 2016;17: pubmed publisher
  • immunocytochemistry; human; 1:50; fig 2
Yang Y, Xu Y, Ding C, Khoudja R, Lin M, Awonuga A, et al. Comparison of 2, 5, and 20 % O2 on the development of post-thaw human embryos. J Assist Reprod Genet. 2016;33:919-27 pubmed publisher
  • immunohistochemistry - paraffin section; rat; fig 4
Abdel Hamid A, Firgany A, Ali E. Effect of memantine: A NMDA receptor blocker, on ethambutol-induced retinal injury. Ann Anat. 2016;204:86-92 pubmed publisher
  • western blot; human
Tian F, Clift M, Casey A, del Pino P, Pelaz B, Conde J, et al. Investigating the role of shape on the biological impact of gold nanoparticles in vitro. Nanomedicine (Lond). 2015;10:2643-57 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:500
Jami M, Hou J, Liu M, Varney M, Hassan H, Dong J, et al. Functional proteomic analysis reveals the involvement of KIAA1199 in breast cancer growth, motility and invasiveness. BMC Cancer. 2014;14:194 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:500
Ng T, Wert D, Sohi H, Procissi D, Colcher D, Raubitschek A, et al. Serial diffusion MRI to monitor and model treatment response of the targeted nanotherapy CRLX101. Clin Cancer Res. 2013;19:2518-27 pubmed publisher
  • immunocytochemistry; human
  • western blot; human
Pfister C, Pfrommer H, Tatagiba M, Roser F. Detection and quantification of farnesol-induced apoptosis in difficult primary cell cultures by TaqMan protein assay. Apoptosis. 2013;18:452-66 pubmed publisher
  • immunohistochemistry - paraffin section; rat; fig 4B
Uhal B, Rayford H, Zhuang J, Li X, Laukka J, Soledad Conrad V. Apoptosis-dependent acute lung injury and repair after intratracheal instillation of noradrenaline in rats. Exp Physiol. 2003;88:269-75 pubmed
Che S, Bie L, Li X, Qi H, Yu P, Zuo L. Parthenolide inhibits the proliferation and induces the apoptosis of human uveal melanoma cells. Int J Ophthalmol. 2019;12:1531-1538 pubmed publisher
Qian Y, Wu H, Liu G, Ren C, Lu P, Zhang X. Blockade of insulin receptor substrate-1 inhibits biological behavior of choroidal endothelial cells. Int J Ophthalmol. 2019;12:1386-1394 pubmed publisher
Carpenter E, Chagani S, Nelson D, Cassidy P, Laws M, Ganguli Indra G, et al. Mitochondrial complex I inhibitor deguelin induces metabolic reprogramming and sensitizes vemurafenib-resistant BRAFV600E mutation bearing metastatic melanoma cells. Mol Carcinog. 2019;58:1680-1690 pubmed publisher
Tseeleesuren D, Kant R, Yen C, Hsiao H, Chen Y. 1,2,3,4,6-Penta-O-Galloyl-Beta-D-Glucopyranoside Inhibits Proliferation of Multiple Myeloma Cells Accompanied with Suppression of MYC Expression. Front Pharmacol. 2018;9:65 pubmed publisher
Weng Y, Wang X, An R, Cassin J, Vissers C, Liu Y, et al. Epitranscriptomic m6A Regulation of Axon Regeneration in the Adult Mammalian Nervous System. Neuron. 2018;97:313-325.e6 pubmed publisher
Weng Y, An R, Cassin J, Joseph J, Mi R, Wang C, et al. An Intrinsic Epigenetic Barrier for Functional Axon Regeneration. Neuron. 2017;94:337-346.e6 pubmed publisher
Shan T, Shan T, Liu F, Zheng H, Li G. Effects of Lycium barbarum polysaccharides on the damage to human endometrial stromal cells induced by hydrogen peroxide. Mol Med Rep. 2017;15:879-884 pubmed publisher
Pfister C, Pfrommer H, Tatagiba M, Roser F. Detection and quantification of apoptosis in primary cells using Taqman® protein assay. Methods Mol Biol. 2015;1219:57-73 pubmed publisher
Wang H, Wang W, Cornish K, Rozanski G, Zucker I. Cardiac sympathetic afferent denervation attenuates cardiac remodeling and improves cardiovascular dysfunction in rats with heart failure. Hypertension. 2014;64:745-55 pubmed publisher
Farmer C, Palin M, Martel Kennes Y. Impact of diet deprivation and subsequent overallowance during gestation on mammary gland development and lactation performance. J Anim Sci. 2014;92:141-51 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Caspase 3 Recombinant Rabbit Monoclonal Antibody (9H19L2)
Catalog # :
700182
Quantity :
100 µg
Price :
US 425.00
Clonality :
Recombinant Monoclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
Immunocytochemistry: 1-2 µg/mL, Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 0.1-0.2 µg/mL
Species :
Human, Mouse
Clone :
9H19L2
Isotype :
IgG
Storage :
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Description :
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
Immunogen :
A peptide corresponding to amino acids 171-175 of P42574.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1-2 µg/mL, Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 0.1-0.2 µg/mL
Aliases :
A830040C14Rik; AC-3; Apopain; Apopain precursor; Casp3; CASP-3; caspase 3; Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis related cysteine protease; Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; Caspase3; caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; Caspase-3-like protein; CC3; Cpp32; CPP-32; CPP32B; CPP32beta; cysteine protease CPP32; cysteine protease; CPP32; apopain; ICE3; IRP; LICE; mldy; PARP cleavage protease; procaspase3; protein Yama; SCA-1; SREBP cleavage activity 1; Yama; yama protein
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA