| Reference |
|---|
Brachelente C, Torrigiani F, Porcellato I, Drigo M, Brescia M, Treggiari E, et al. Tumor Immune Microenvironment and Its Clinicopathological and Prognostic Associations in Canine Splenic Hemangiosarcoma. Animals (Basel). 2024;14: pubmed publisher |
Ram S, Mojtahedzadeh S, Aguilar J, Coskran T, Powell E, O Neil S. Quantitative performance assessment of Ultivue multiplex panels in formalin-fixed, paraffin-embedded human and murine tumor specimens. Sci Rep. 2024;14:8496 pubmed publisher |
Linnerbauer M, L xf6 xdf lein L, Vandrey O, Peter A, Han Y, Tsaktanis T, et al. The astrocyte-produced growth factor HB-EGF limits autoimmune CNS pathology. Nat Immunol. 2024;25:432-447 pubmed publisher |
Lantz B, Moriwaki M, Oyebamiji O, Guo Y, Gonzalez Bosc L. Chronic hypoxia disrupts T regulatory cell phenotype contributing to the emergence of exTreg-TH17 cells. Front Physiol. 2023;14:1304732 pubmed publisher |
Sandoval S, Malany K, Thongphanh K, Martinez C, Goodson M, Souza F, et al. Activation of the aryl hydrocarbon receptor inhibits neuropilin-1 upregulation on IL-2-responding CD4+ T cells. Front Immunol. 2023;14:1193535 pubmed publisher |
Chen L, Huang Y, Chen Y, Chen J, You X, Zou L, et al. Resolvin D1 promotes the resolution of inflammation in the ACLF rat model by increasing the proportion of Treg cells. Immun Inflamm Dis. 2023;11:e1076 pubmed publisher |
Jang S, Kim J, Kim C, Kim I. Hypertonic Salt Solution Enhances Inflammatory Responses in Cultured Splenic T-Cells from Dahl Salt-Sensitive Rats but Not Dahl Salt-Resistant Rats. J Cardiovasc Dev Dis. 2023;10: pubmed publisher |
Lee J, Kim S, Sohn H, Kim C, Kim T, Lee H. Local Myeloid-Derived Suppressor Cells Impair Progression of Experimental Autoimmune Uveitis by Alleviating Oxidative Stress and Inflammation. Invest Ophthalmol Vis Sci. 2023;64:39 pubmed publisher |
Johansson K, Gagnon J, Zhou S, Fassett M, Schroeder A, Kageyama R, et al. An essential role for miR-15/16 in Treg suppression and restriction of proliferation. Cell Rep. 2023;42:113298 pubmed publisher |
Pu S, Yang Z, Zhang X, Li M, Han N, Yang X, et al. Fermented cordyceps powder alleviates silica-induced pulmonary inflammation and fibrosis in rats by regulating the Th immune response. Chin Med. 2023;18:131 pubmed publisher |
Bourebaba L, Serwotka Suszczak A, Bourebaba N, Zyzak M, Marycz K. The PTP1B Inhibitor Trodusquemine (MSI-1436) Improves Glucose Uptake in Equine Metabolic Syndrome Affected Liver through Anti-Inflammatory and Antifibrotic Activity. Int J Inflam. 2023;2023:3803056 pubmed publisher |
Zheng C, Snow B, Elia A, Nechanitzky R, Dominguez Brauer C, Liu S, et al. Tumor-specific cholinergic CD4+ T lymphocytes guide immunosurveillance of hepatocellular carcinoma. Nat Cancer. 2023;4:1437-1454 pubmed publisher |
Ahmadi A, Atiee G, Chapman B, Reynolds L, Sun J, Cameron A, et al. A phase I, first-in-human study to evaluate the safety and tolerability, pharmacokinetics, and pharmacodynamics of MRG-001 in healthy subjects. Cell Rep Med. 2023;4:101169 pubmed publisher |
Arwood M, Sun I, Patel C, Sun I, Oh M, Bettencourt I, et al. Serendipitous Discovery of T Cell-Produced KLK1b22 as a Regulator of Systemic Metabolism. Immunohorizons. 2023;7:493-507 pubmed publisher |
Shahine Y, El Aal S, Reda A, Sheta E, Atia N, Abdallah O, et al. Diosmin nanocrystal gel alleviates imiquimod-induced psoriasis in rats via modulating TLR7,8/NF-κB/micro RNA-31, AKT/mTOR/P70S6K milieu, and Tregs/Th17 balance. Inflammopharmacology. 2023;31:1341-1359 pubmed publisher |
Celesti F, Gatta A, Shallak M, Chiaravalli A, Cerati M, Sessa F, et al. Protective anti-tumor vaccination against glioblastoma expressing the MHC class II transactivator CIITA. Front Immunol. 2023;14:1133177 pubmed publisher |
Read K, Jones D, Pokhrel S, Hales E, Varkey A, Tuazon J, et al. Aiolos represses CD4+ T cell cytotoxic programming via reciprocal regulation of TFH transcription factors and IL-2 sensitivity. Nat Commun. 2023;14:1652 pubmed publisher |
Choi B, Park M, Park K, Han W, Yoon H, Jung H, et al. Immunotherapy targeting plasma ASM is protective in a mouse model of Alzheimer's disease. Nat Commun. 2023;14:1631 pubmed publisher |
Reijers I, Rao D, Versluis J, Menzies A, Dimitriadis P, Wouters M, et al. IFN-γ signature enables selection of neoadjuvant treatment in patients with stage III melanoma. J Exp Med. 2023;220: pubmed publisher |
Schwarz A, Philippsen R, Piticchio S, Hartmann J, H xe4 sler R, Rose John S, et al. Crosstalk between microbiome, regulatory T cells and HCA2 orchestrates the inflammatory response in a murine psoriasis model. Front Immunol. 2023;14:1038689 pubmed publisher |
Lee A, Woo J, Lee S, Lee Y, Jung J, Lee C, et al. SARS-CoV-2 spike protein promotes inflammatory cytokine activation and aggravates rheumatoid arthritis. Cell Commun Signal. 2023;21:44 pubmed publisher |
Zhu X, Li Q, George V, Spanoudis C, Gilkes C, Shrestha N, et al. A novel interleukin-2-based fusion molecule, HCW9302, differentially promotes regulatory T cell expansion to treat atherosclerosis in mice. Front Immunol. 2023;14:1114802 pubmed publisher |
O Neill T, Gewies A, Seeholzer T, Krappmann D. TRAF6 controls T cell homeostasis by maintaining the equilibrium of MALT1 scaffolding and protease functions. Front Immunol. 2023;14:1111398 pubmed publisher |
Xu B, Shimauchi Ohtaki H, Yoshimoto Y, Sadakata T, Ishizaki Y. Transplanted human iPSC-derived vascular endothelial cells promote functional recovery by recruitment of regulatory T cells to ischemic white matter in the brain. J Neuroinflammation. 2023;20:11 pubmed publisher |
Zhang Y, Liu T, Deng Z, Fang W, Zhang X, Zhang S, et al. Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils. Adv Sci (Weinh). 2023;10:e2206958 pubmed publisher |
Zhang Z, Xie K, Luo R, Zhang D, He Z, Li K, et al. Dexmedetomidine alleviates acute lung injury by promoting Tregs differentiation via activation of AMPK/SIRT1 pathway. Inflammopharmacology. 2023;31:423-438 pubmed publisher |
Tian C, Li M, Shuai X, Jiang F, Dong Y, Gui Y, et al. Berberine plays a cardioprotective role by inhibiting macrophage Wnt5a/β-catenin pathway in the myocardium of mice after myocardial infarction. Phytother Res. 2023;37:50-61 pubmed publisher |
Al Saafeen B, Al Sbiei A, Bashir G, Mohamed Y, Masad R, Fernandez Cabezudo M, et al. Attenuated Salmonella potentiate PD-L1 blockade immunotherapy in a preclinical model of colorectal cancer. Front Immunol. 2022;13:1017780 pubmed publisher |
Yang J, Mai B, Su Y, Liang S, Su Z, Chen Y, et al. Twelve-week high-fat diet for improving adverse ventricular remodeling post-myocardial infarction by alleviating local inflammation. Ann Transl Med. 2022;10:1089 pubmed publisher |
Klaus T, Wilson A, Vicari E, Hadaschik E, Klein M, Helbich S, et al. Impaired Treg-DC interactions contribute to autoimmunity in leukocyte adhesion deficiency type 1. JCI Insight. 2022;7: pubmed publisher |
Mauda Havakuk M, Hawken N, Owen J, Mikhail A, Saxena A, Karim B, et al. Comparative analysis of the immune response to RFA and cryoablation in a colon cancer mouse model. Sci Rep. 2022;12:18229 pubmed publisher |
Lopez Krol A, Nehring H, Krause F, Wempe A, Raifer H, Nist A, et al. Lactate induces metabolic and epigenetic reprogramming of pro-inflammatory Th17 cells. EMBO Rep. 2022;23:e54685 pubmed publisher |
Araki H, Tazawa H, Kanaya N, Kajiwara Y, Yamada M, Hashimoto M, et al. Oncolytic virus-mediated p53 overexpression promotes immunogenic cell death and efficacy of PD-1 blockade in pancreatic cancer. Mol Ther Oncolytics. 2022;27:3-13 pubmed publisher |
Lin A, De Backer J, Quatannens D, Cuypers B, Verswyvel H, De La Hoz E, et al. The effect of local non-thermal plasma therapy on the cancer-immunity cycle in a melanoma mouse model. Bioeng Transl Med. 2022;7:e10314 pubmed publisher |
Chryplewicz A, Scotton J, Tichet M, Zomer A, Shchors K, Joyce J, et al. Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity. Cancer Cell. 2022;40:1111-1127.e9 pubmed publisher |
Kang J, Lee H, Lee J, Hong J, Hong Kim Y, Disis M, et al. Novel peptide-based vaccine targeting heat shock protein 90 induces effective antitumor immunity in a HER2+ breast cancer murine model. J Immunother Cancer. 2022;10: pubmed publisher |
Ponzo M, Debesset A, Cossutta M, Chalabi Dchar M, Houppe C, Pilon C, et al. Nucleolin Therapeutic Targeting Decreases Pancreatic Cancer Immunosuppression. Cancers (Basel). 2022;14: pubmed publisher |
Mej xed a Hern xe1 ndez J, Keam S, Saleh R, Muntz F, Fox S, Byrne D, et al. Modelling aggressive prostate cancers of young men in immune-competent mice, driven by isogenic Trp53 alterations and Pten loss. Cell Death Dis. 2022;13:777 pubmed publisher |
Ma S, Hernandez J, HUANG W. Protocol to assess cell-intrinsic regulatory mechanisms using an ex vivo murine T cell polarization and co-culture system. STAR Protoc. 2022;3:101543 pubmed publisher |
Zhou C, Ma L, Xu H, Huo Y, Luo J. Meningeal lymphatics regulate radiotherapy efficacy through modulating anti-tumor immunity. Cell Res. 2022;32:543-554 pubmed publisher |
Zou Q, Liu C, Hu N, Wang W, Wang H. miR-126 ameliorates multiple organ dysfunction in septic rats by regulating the differentiation of Th17/Treg. Mol Biol Rep. 2022;49:2985-2998 pubmed publisher |
Trofimova O, Korotkaja K, Skrastina D, Jansons J, Spunde K, Isaguliants M, et al. Alphavirus-Driven Interferon Gamma (IFNg) Expression Inhibits Tumor Growth in Orthotopic 4T1 Breast Cancer Model. Vaccines (Basel). 2021;9: pubmed publisher |
Schmidtke L, Meineck M, Saurin S, Otten S, Gather F, Schrick K, et al. Knockout of the KH-Type Splicing Regulatory Protein Drives Glomerulonephritis in MRL-Faslpr Mice. Cells. 2021;10: pubmed publisher |
Fotheringham A, Solon Biet S, Bielefeldt Ohmann H, McCarthy D, McMahon A, Ruohonen K, et al. Kidney disease risk factors do not explain impacts of low dietary protein on kidney function and structure. iScience. 2021;24:103308 pubmed publisher |
Teng F, Tach xf3 Pi xf1 ot R, Sung B, Farber D, Worgall S, Hammad H, et al. ILC3s control airway inflammation by limiting T cell responses to allergens and microbes. Cell Rep. 2021;37:110051 pubmed publisher |
Qadir A, Guegan J, Ginestier C, Chaibi A, Bessede A, Charafe Jauffret E, et al. CD95/Fas protects triple negative breast cancer from anti-tumor activity of NK cells. iScience. 2021;24:103348 pubmed publisher |
Pang L, Ernst M, Huynh J. Development of a Multiplex Immunohistochemistry Workflow to Investigate the Immune Microenvironment in Mouse Models of Inflammatory Bowel Disease and Colon Cancer. Int J Mol Sci. 2021;22: pubmed publisher |
Chao J, Korzinkin M, Zhavoronkov A, Ozerov I, Walker M, Higgins K, et al. Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma. Cell Rep Med. 2021;2:100399 pubmed publisher |
Huang C, Shen Y, Shen M, Fan X, Men R, Ye T, et al. Glucose Metabolism Reprogramming of Regulatory T Cells in Concanavalin A-Induced Hepatitis. Front Pharmacol. 2021;12:726128 pubmed publisher |
Hu W, Wang Z, Feng Y, Schizas M, Hoyos B, van der Veeken J, et al. Regulatory T cells function in established systemic inflammation and reverse fatal autoimmunity. Nat Immunol. 2021;22:1163-1174 pubmed publisher |
Tong L, Hao H, Zhang Z, Lv Y, Liang X, Liu Q, et al. Milk-derived extracellular vesicles alleviate ulcerative colitis by regulating the gut immunity and reshaping the gut microbiota. Theranostics. 2021;11:8570-8586 pubmed publisher |
Wan N, Rong W, Zhu W, Jia D, Bai P, Liu G, et al. Tregs-derived interleukin 35 attenuates endothelial proliferation through STAT1 in pulmonary hypertension. Ann Transl Med. 2021;9:926 pubmed publisher |
Vito A, Salem O, El Sayes N, MacFawn I, Portillo A, Milne K, et al. Immune checkpoint blockade in triple negative breast cancer influenced by B cells through myeloid-derived suppressor cells. Commun Biol. 2021;4:859 pubmed publisher |
Heimesaat M, Weschka D, Mousavi S, Bereswill S. Treatment with the Probiotic Product Aviguard® Alleviates Inflammatory Responses during Campylobacter jejuni-Induced Acute Enterocolitis in Mice. Int J Mol Sci. 2021;22: pubmed publisher |
Furesi G, Fert I, Beaufr xe8 re M, Araujo L, Glatigny S, Baschant U, et al. Rodent Models of Spondyloarthritis Have Decreased White and Bone Marrow Adipose Tissue Depots. Front Immunol. 2021;12:665208 pubmed publisher |
Chen L, Chen H, Ye J, Ge Y, Wang H, Dai E, et al. Intratumoral expression of interleukin 23 variants using oncolytic vaccinia virus elicit potent antitumor effects on multiple tumor models via tumor microenvironment modulation. Theranostics. 2021;11:6668-6681 pubmed publisher |
Wang Y, Gu T, Tian X, Li W, Zhao R, Yang W, et al. A Small Molecule Antagonist of PD-1/PD-L1 Interactions Acts as an Immune Checkpoint Inhibitor for NSCLC and Melanoma Immunotherapy. Front Immunol. 2021;12:654463 pubmed publisher |
Amobi McCloud A, Muthuswamy R, Battaglia S, Yu H, Liu T, Wang J, et al. IDO1 Expression in Ovarian Cancer Induces PD-1 in T Cells via Aryl Hydrocarbon Receptor Activation. Front Immunol. 2021;12:678999 pubmed publisher |
Dá Mesquita S, Herz J, Wall M, Dykstra T, de Lima K, Norris G, et al. Aging-associated deficit in CCR7 is linked to worsened glymphatic function, cognition, neuroinflammation, and β-amyloid pathology. Sci Adv. 2021;7: pubmed publisher |
Yang L, Jing Y, Kang D, Jiang P, Li N, Zhou X, et al. Ubiquitin-specific peptidase 18 regulates the differentiation and function of Treg cells. Genes Dis. 2021;8:344-352 pubmed publisher |
Bartlett A, Pennock N, Klug A, Schedin P. Immune Milieu Established by Postpartum Liver Involution Promotes Breast Cancer Liver Metastasis. Cancers (Basel). 2021;13: pubmed publisher |
Harb H, Benamar M, Lai P, Contini P, Griffith J, Crestani E, et al. Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections. Immunity. 2021;54:1186-1199.e7 pubmed publisher |
Zhang Q, Liang Z, Zhang J, Lei T, Dong X, Su H, et al. Sirt6 Regulates the Development of Medullary Thymic Epithelial Cells and Contributes to the Establishment of Central Immune Tolerance. Front Cell Dev Biol. 2021;9:655552 pubmed publisher |
Li W, Luo Y, Xu H, Ma Q, Yao Q. Imbalance between T helper 1 and regulatory T cells plays a detrimental role in experimental Parkinson's disease in mice. J Int Med Res. 2021;49:300060521998471 pubmed publisher |
Thomas R, Oh J, Wang W, Su D. Thymic atrophy creates holes in Treg-mediated immuno-regulation via impairment of an antigen-specific clone. Immunology. 2021;163:478-492 pubmed publisher |
Vankerckhoven A, Baert T, Riva M, De Bruyn C, Thirion G, Vandenbrande K, et al. Type of chemotherapy has substantial effects on the immune system in ovarian cancer. Transl Oncol. 2021;14:101076 pubmed publisher |
Liu X, Jiang J, Liao Y, Tang I, Zheng E, Qiu W, et al. Combination Chemo-Immunotherapy for Pancreatic Cancer Using the Immunogenic Effects of an Irinotecan Silicasome Nanocarrier Plus Anti-PD-1. Adv Sci (Weinh). 2021;8:2002147 pubmed publisher |
Yang P, Tian H, Zou Y, Chambon P, Ichinose H, Honig G, et al. Epinephrine Production in Th17 Cells and Experimental Autoimmune Encephalitis. Front Immunol. 2021;12:616583 pubmed publisher |
Kim J, Lee E, Koo S, Kim C, Kim I. Transfer of Th17 from Adult Spontaneous Hypertensive Rats Accelerates Development of Hypertension in Juvenile Spontaneous Hypertensive Rats. Biomed Res Int. 2021;2021:6633825 pubmed publisher |
Pang L, Huynh J, Alorro M, Li X, Ernst M, Chand A. STAT3 Signalling via the IL-6ST/gp130 Cytokine Receptor Promotes Epithelial Integrity and Intestinal Barrier Function during DSS-Induced Colitis. Biomedicines. 2021;9: pubmed publisher |
Amend A, Wickli N, Schäfer A, Sprenger D, Manz R, Voll R, et al. Dual Role of Interleukin-10 in Murine NZB/W F1 Lupus. Int J Mol Sci. 2021;22: pubmed publisher |
Malone K, Diaz Diaz A, Shearer J, Moore A, Waeber C. The effect of fingolimod on regulatory T cells in a mouse model of brain ischaemia. J Neuroinflammation. 2021;18:37 pubmed publisher |
Kim S, Kim S, Nam G, Hong Y, Kim G, Choi Y, et al. In situ immunogenic clearance induced by a combination of photodynamic therapy and rho-kinase inhibition sensitizes immune checkpoint blockade response to elicit systemic antitumor immunity against intraocular melanoma and its metastasis. J Immunother Cancer. 2021;9: pubmed publisher |
Huang C, Li Z, Zhu J, Chen X, Hao Y, Yang R, et al. Systems pharmacology dissection of Epimedium targeting tumor microenvironment to enhance cytotoxic T lymphocyte responses in lung cancer. Aging (Albany NY). 2021;13:2912-2940 pubmed publisher |
Bianchi A, Marchetti L, Hall Z, Lemos H, Vacca M, Paish H, et al. Moderate Exercise Inhibits Age-Related Inflammation, Liver Steatosis, Senescence, and Tumorigenesis. J Immunol. 2021;206:904-916 pubmed publisher |
Li C, Park J. Assessing IL-2-Induced STAT5 Phosphorylation in Fixed, Permeabilized Foxp3+ Treg Cells by Multiparameter Flow Cytometry. STAR Protoc. 2020;1:100195 pubmed publisher |
Mousavi S, Weschka D, Bereswill S, Heimesaat M. Preclinical Evaluation of Oral Urolithin-A for the Treatment of Acute Campylobacteriosis in Campylobacter jejuni Infected Microbiota-Depleted IL-10-/- Mice. Pathogens. 2020;10: pubmed publisher |
Ebelt N, Zuniga E, Marzagalli M, Zamloot V, Blazar B, Salgia R, et al. Salmonella-Based Therapy Targeting Indoleamine 2,3-Dioxygenase Restructures the Immune Contexture to Improve Checkpoint Blockade Efficacy. Biomedicines. 2020;8: pubmed publisher |
Luo Y, Wang B, Liu J, Ma F, Luo D, Zheng Z, et al. Ginsenoside RG1 enhances the paracrine effects of bone marrow-derived mesenchymal stem cells on radiation induced intestinal injury. Aging (Albany NY). 2020;13:1132-1152 pubmed publisher |
Jin L, Hu Q, Hu Y, Chen Z, Liao W. Respiratory Syncytial Virus Infection Reduces Kynurenic Acid Production and Reverses Th17/Treg Balance by Modulating Indoleamine 2,3-Dioxygenase (IDO) Molecules in Plasmacytoid Dendritic Cells. Med Sci Monit. 2020;26:e926763 pubmed publisher |
Nguyen H, Ticer T, Bastian D, Kuril S, Li H, Du H, et al. Lysosomal Acid Lipase Is Required for Donor T Cells to Induce Graft-versus-Host Disease. Cell Rep. 2020;33:108316 pubmed publisher |
Wirasinha R, Davies A, Srivastava M, Sheridan J, Sng X, Delmonte O, et al. Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility. J Exp Med. 2021;218: pubmed publisher |
Heimesaat M, Mousavi S, Kl xf8 ve S, Genger C, Weschka D, Tamas A, et al. Pituitary Adenylate Cyclase-Activating Polypeptide Alleviates Intestinal, Extra-Intestinal and Systemic Inflammatory Responses during Acute Campylobacter jejuni-induced Enterocolitis in Mice. Pathogens. 2020;9: pubmed publisher |
Heimesaat M, Genger C, Klove S, Weschka D, Mousavi S, Bereswill S. The Host-Specific Intestinal Microbiota Composition Impacts Campylobacter coli Infection in a Clinical Mouse Model of Campylobacteriosis. Pathogens. 2020;9: pubmed publisher |
Jackson Thompson B, Torrero M, Mitre B, Long J, Packiam M, Mitre E. Axenic Caenorhabditis elegans antigen protects against development of type-1 diabetes in NOD mice. J Transl Autoimmun. 2020;3:100065 pubmed publisher |
Harb H, Stephen Victor E, Crestani E, Benamar M, Massoud A, Cui Y, et al. A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma. Nat Immunol. 2020;21:1359-1370 pubmed publisher |
Ko H, Hong S, Verma R, Jung J, Lee M, Kim N, et al. Dietary Glucose Consumption Promotes RALDH Activity in Small Intestinal CD103+CD11b+ Dendritic Cells. Front Immunol. 2020;11:1897 pubmed publisher |
Campesato L, Budhu S, Tchaicha J, Weng C, Gigoux M, Cohen I, et al. Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine. Nat Commun. 2020;11:4011 pubmed publisher |
Niu L, Lou F, Sun Y, Sun L, Cai X, Liu Z, et al. A micropeptide encoded by lncRNA MIR155HG suppresses autoimmune inflammation via modulating antigen presentation. Sci Adv. 2020;6:eaaz2059 pubmed publisher |
Heimesaat M, Genger C, Biesemeier N, Klove S, Weschka D, Mousavi S, et al. Inflammatory Immune Responses and Gut Microbiota Changes Following Campylobacter coli Infection of IL-10-/- Mice with Chronic Colitis. Pathogens. 2020;9: pubmed publisher |
Loo C, Gatchalian J, Liang Y, Leblanc M, Xie M, Ho J, et al. A Genome-wide CRISPR Screen Reveals a Role for the Non-canonical Nucleosome-Remodeling BAF Complex in Foxp3 Expression and Regulatory T Cell Function. Immunity. 2020;53:143-157.e8 pubmed publisher |
Wang A, Yang M, Liang R, Zhu F, Zhu F, Liu X, et al. Mouse Double Minute 2 Homolog-Mediated Ubiquitination Facilitates Forkhead Box P3 Stability and Positively Modulates Human Regulatory T Cell Function. Front Immunol. 2020;11:1087 pubmed publisher |
Shi Y, Fu Y, Zhang X, Zhao G, Yao Y, Guo Y, et al. Romidepsin (FK228) regulates the expression of the immune checkpoint ligand PD-L1 and suppresses cellular immune functions in colon cancer. Cancer Immunol Immunother. 2021;70:61-73 pubmed publisher |
Son S, Park S, Koh J, Im D. Free fatty acid receptor 4 (FFA4) activation ameliorates 2,4-dinitrochlorobenzene-induced atopic dermatitis by increasing regulatory T cells in mice. Acta Pharmacol Sin. 2020;41:1337-1347 pubmed publisher |
Gniadek T, Augustin L, Schottel J, Leonard A, Saltzman D, Greeno E, et al. A Phase I, Dose Escalation, Single Dose Trial of Oral Attenuated Salmonella typhimurium Containing Human IL-2 in Patients With Metastatic Gastrointestinal Cancers. J Immunother. 2020;43:217-221 pubmed publisher |
Wang L, Wang Z, Han R, Samanta A, Ge G, Levin L, et al. Donor bone-marrow CXCR4+ Foxp3+ T-regulatory cells are essential for costimulation blockade-induced long-term survival of murine limb transplants. Sci Rep. 2020;10:9292 pubmed publisher |
Kløve S, Genger C, Mousavi S, Weschka D, Bereswill S, Heimesaat M. Toll-Like Receptor-4 Dependent Intestinal and Systemic Sequelae Following Peroral Campylobacter coli Infection of IL10 Deficient Mice Harboring a Human Gut Microbiota. Pathogens. 2020;9: pubmed publisher |
Shiuan E, Inala A, Wang S, Song W, Youngblood V, Chen J, et al. Host deficiency in ephrin-A1 inhibits breast cancer metastasis. F1000Res. 2020;9:217 pubmed publisher |
Kim Y, Park S, Ha H, Lee A, Won H, Cha H, et al. HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment. J Cancer. 2020;11:4059-4072 pubmed publisher |
Baumann D, Hägele T, Mochayedi J, Drebant J, Vent C, Blobner S, et al. Proimmunogenic impact of MEK inhibition synergizes with agonist anti-CD40 immunostimulatory antibodies in tumor therapy. Nat Commun. 2020;11:2176 pubmed publisher |
Gladow N, Hollmann C, Ramos G, Frantz S, Kerkau T, Beyersdorf N, et al. Treatment of mice with a ligand binding blocking anti-CD28 monoclonal antibody improves healing after myocardial infarction. PLoS ONE. 2020;15:e0227734 pubmed publisher |
Kang L, Oh E, Cho C, Kwon H, Lee C, Jeon J, et al. 3'-Sialyllactose prebiotics prevents skin inflammation via regulatory T cell differentiation in atopic dermatitis mouse models. Sci Rep. 2020;10:5603 pubmed publisher |
Hrdý J, Alard J, Couturier Maillard A, Boulard O, Boutillier D, Delacre M, et al. Lactobacillus reuteri 5454 and Bifidobacterium animalis ssp. lactis 5764 improve colitis while differentially impacting dendritic cells maturation and antimicrobial responses. Sci Rep. 2020;10:5345 pubmed publisher |
Lee E, Kim N, Kang J, Yoon S, Lee H, Jung H, et al. Activated pathogenic Th17 lymphocytes induce hypertension following high-fructose intake in Dahl salt-sensitive but not Dahl salt-resistant rats. Dis Model Mech. 2020;13: pubmed publisher |
Wijesekera D, Yuba E, De Silva N, Watanabe S, Tsukamoto M, Ichida C, et al. Manipulation of the tumor microenvironment by cytokine gene transfection enhances dendritic cell-based immunotherapy. FASEB Bioadv. 2020;2:5-17 pubmed publisher |
Webb L, Sengupta S, Edell C, Piedra Quintero Z, Amici S, Miranda J, et al. Protein arginine methyltransferase 5 promotes cholesterol biosynthesis-mediated Th17 responses and autoimmunity. J Clin Invest. 2020;130:1683-1698 pubmed publisher |
van Sadelhoff J, Hogenkamp A, Wiertsema S, Harthoorn L, Loonstra R, Hartog A, et al. A free amino acid-based diet partially prevents symptoms of cow's milk allergy in mice after oral sensitization with whey. Immun Inflamm Dis. 2020;8:93-105 pubmed publisher |
Li P, Wang J, Guo F, Zheng B, Zhang X. A novel inhibitory role of microRNA-224 in particulate matter 2.5-induced asthmatic mice by inhibiting TLR2. J Cell Mol Med. 2020;24:3040-3052 pubmed publisher |
Vanderleyden I, Fra Bido S, Innocentin S, Stebegg M, Okkenhaug H, Evans Bailey N, et al. Follicular Regulatory T Cells Can Access the Germinal Center Independently of CXCR5. Cell Rep. 2020;30:611-619.e4 pubmed publisher |
Takaku S, Shimizu M, Takahashi H. Japanese Kampo Medicine Juzentaihoto Enhances Antitumor Immunity in CD1d-/- Mice Lacking NKT Cells. Integr Cancer Ther. 2020;19:1534735419900798 pubmed publisher |
Rosenbaum S, Knecht M, Mollaee M, Zhong Z, Erkes D, McCue P, et al. FOXD3 Regulates VISTA Expression in Melanoma. Cell Rep. 2020;30:510-524.e6 pubmed publisher |
Anderson J, Kol A, Bizikova P, Stapelton B, Ford K, Villarreal A, et al. Immunopathogenesis of canine chronic ulcerative stomatitis. PLoS ONE. 2020;15:e0227386 pubmed publisher |
Brichacek A, Benkovic S, Chakraborty S, Nwafor D, Wang W, Jun S, et al. Systemic inhibition of tissue-nonspecific alkaline phosphatase alters the brain-immune axis in experimental sepsis. Sci Rep. 2019;9:18788 pubmed publisher |
Wu R, Liu C, Deng X, Chen L, Hao S, Ma L. Enhanced alleviation of aGVHD by TGF-β1-modified mesenchymal stem cells in mice through shifting MΦ into M2 phenotype and promoting the differentiation of Treg cells. J Cell Mol Med. 2020;24:1684-1699 pubmed publisher |
Carper M, Troutman S, Wagner B, Byrd K, Selitsky S, Parag Sharma K, et al. An Immunocompetent Mouse Model of HPV16(+) Head and Neck Squamous Cell Carcinoma. Cell Rep. 2019;29:1660-1674.e7 pubmed publisher |
Bishehsari F, Engen P, VOIGT R, Swanson G, Shaikh M, Wilber S, et al. Abnormal Eating Patterns Cause Circadian Disruption and Promote Alcohol-Associated Colon Carcinogenesis. Cell Mol Gastroenterol Hepatol. 2020;9:219-237 pubmed publisher |
Strattan E, Palaniyandi S, Kumari R, Du J, Hakim N, Huang T, et al. Mast Cells Are Mediators of Fibrosis and Effector Cell Recruitment in Dermal Chronic Graft-vs.-Host Disease. Front Immunol. 2019;10:2470 pubmed publisher |
Kusano T, Ehirchiou D, Matsumura T, Chobaz V, Nasi S, Castelblanco M, et al. Targeted knock-in mice expressing the oxidase-fixed form of xanthine oxidoreductase favor tumor growth. Nat Commun. 2019;10:4904 pubmed publisher |
Kuehlwein J, Borsche M, Korir P, Risch F, Mueller A, Hübner M, et al. Protection of Batf3-deficient mice from experimental cerebral malaria correlates with impaired cytotoxic T-cell responses and immune regulation. Immunology. 2020;159:193-204 pubmed publisher |
Zammit N, Walters S, Seeberger K, O Connell P, Korbutt G, Grey S. A20 as an immune tolerance factor can determine islet transplant outcomes. JCI Insight. 2019;4: pubmed publisher |
Abughanam G, Elkashty O, Liu Y, Bakkar M, Tran S. Mesenchymal Stem Cells Extract (MSCsE)-Based Therapy Alleviates Xerostomia and Keratoconjunctivitis Sicca in Sjogren's Syndrome-Like Disease. Int J Mol Sci. 2019;20: pubmed publisher |
Mousavi S, Lobo de Sá F, Schulzke J, Bücker R, Bereswill S, Heimesaat M. Vitamin D in Acute Campylobacteriosis-Results From an Intervention Study Applying a Clinical Campylobacter jejuni Induced Enterocolitis Model. Front Immunol. 2019;10:2094 pubmed publisher |
Xu J, Pei S, Wang Y, Liu J, Qian Y, Huang M, et al. Tpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells. Front Immunol. 2019;10:1980 pubmed publisher |
Saldinger L, Nelson S, Bellone R, Lassaline M, Mack M, Walker N, et al. Horses with equine recurrent uveitis have an activated CD4+ T-cell phenotype that can be modulated by mesenchymal stem cells in vitro. Vet Ophthalmol. 2020;23:160-170 pubmed publisher |
Thomas S, Kuncheria L, Roulstone V, Kyula J, Mansfield D, Bommareddy P, et al. Development of a new fusion-enhanced oncolytic immunotherapy platform based on herpes simplex virus type 1. J Immunother Cancer. 2019;7:214 pubmed publisher |
Kim S, García Recio S, Creighton C, Perou C, Rosen J. Alterations in Wnt- and/or STAT3 signaling pathways and the immune microenvironment during metastatic progression. Oncogene. 2019;38:5942-5958 pubmed publisher |
Fu Z, Ye J, Dean J, Bostick J, Weinberg S, Xiong L, et al. Requirement of Mitochondrial Transcription Factor A in Tissue-Resident Regulatory T Cell Maintenance and Function. Cell Rep. 2019;28:159-171.e4 pubmed publisher |
Zhang Y, Du X, Liu M, Tang F, Zhang P, Ai C, et al. Hijacking antibody-induced CTLA-4 lysosomal degradation for safer and more effective cancer immunotherapy. Cell Res. 2019;29:609-627 pubmed publisher |
Eissmann M, Dijkstra C, Jarnicki A, Phesse T, Brunnberg J, Poh A, et al. IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization. Nat Commun. 2019;10:2735 pubmed publisher |
Martinez Vélez N, Garcia Moure M, Marigil M, Gonzalez Huarriz M, Puigdelloses M, Gallego Perez Larraya J, et al. The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models. Nat Commun. 2019;10:2235 pubmed publisher |
Ramakrishna C, Kujawski M, Chu H, Li L, Mazmanian S, CANTIN E. Bacteroides fragilis polysaccharide A induces IL-10 secreting B and T cells that prevent viral encephalitis. Nat Commun. 2019;10:2153 pubmed publisher |
Yue X, Lio C, Samaniego Castruita D, Li X, Rao A. Loss of TET2 and TET3 in regulatory T cells unleashes effector function. Nat Commun. 2019;10:2011 pubmed publisher |
Uehara M, Li X, Sheikhi A, Zandi N, Walker B, Saleh B, et al. Anti-IL-6 eluting immunomodulatory biomaterials prolong skin allograft survival. Sci Rep. 2019;9:6535 pubmed publisher |
Zhou Y, Fu C, Kong Y, Pan D, Wang Y, Huang S, et al. Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models. Anticancer Drugs. 2019;30:909-916 pubmed publisher |
Esterházy D, Canesso M, Mesin L, Muller P, de Castro T, Lockhart A, et al. Compartmentalized gut lymph node drainage dictates adaptive immune responses. Nature. 2019;569:126-130 pubmed publisher |
Fleskens V, Minutti C, Wu X, Wei P, Pals C, McCrae J, et al. Nemo-like Kinase Drives Foxp3 Stability and Is Critical for Maintenance of Immune Tolerance by Regulatory T Cells. Cell Rep. 2019;26:3600-3612.e6 pubmed publisher |
Xu Y, Tang X, Yang M, Zhang S, Li S, Chen Y, et al. Interleukin 10 Gene-Modified Bone Marrow-Derived Dendritic Cells Attenuate Liver Fibrosis in Mice by Inducing Regulatory T Cells and Inhibiting the TGF-β/Smad Signaling Pathway. Mediators Inflamm. 2019;2019:4652596 pubmed publisher |
Amir M, Chaudhari S, Wang R, Campbell S, Mosure S, Chopp L, et al. REV-ERBα Regulates TH17 Cell Development and Autoimmunity. Cell Rep. 2018;25:3733-3749.e8 pubmed publisher |
Chen S, Fang L, Guo W, Zhou Y, Yu G, Li W, et al. Control of Treg cell homeostasis and immune equilibrium by Lkb1 in dendritic cells. Nat Commun. 2018;9:5298 pubmed publisher |
Pai C, Simons D, Lu X, Evans M, Wei J, Wang Y, et al. Tumor-conditional anti-CTLA4 uncouples antitumor efficacy from immunotherapy-related toxicity. J Clin Invest. 2019;129:349-363 pubmed publisher |
Shi H, Liu C, Tan H, Li Y, Nguyen T, Dhungana Y, et al. Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R-STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity. Immunity. 2018;49:899-914.e6 pubmed publisher |
Liu Z, Ge Y, Wang H, Ma C, Feist M, Ju S, et al. Modifying the cancer-immune set point using vaccinia virus expressing re-designed interleukin-2. Nat Commun. 2018;9:4682 pubmed publisher |
Quan S, Principe D, Dean A, Park S, Grippo P, Gius D, et al. Loss of Sirt2 increases and prolongs a caerulein-induced pancreatitis permissive phenotype and induces spontaneous oncogenic Kras mutations in mice. Sci Rep. 2018;8:16501 pubmed publisher |
Hensel J, Khattar V, Ashton R, Ponnazhagan S. Characterization of immune cell subtypes in three commonly used mouse strains reveals gender and strain-specific variations. Lab Invest. 2019;99:93-106 pubmed publisher |
Shrestha A, Bettini M, Menon R, Gopal V, Huang S, Edwards D, et al. Consequences of early postnatal lipopolysaccharide exposure on developing lungs in mice. Am J Physiol Lung Cell Mol Physiol. 2019;316:L229-L244 pubmed publisher |
Pennock N, Martinson H, Guo Q, Betts C, Jindal S, Tsujikawa T, et al. Ibuprofen supports macrophage differentiation, T cell recruitment, and tumor suppression in a model of postpartum breast cancer. J Immunother Cancer. 2018;6:98 pubmed publisher |
Ogawa C, Bankoti R, Nguyen T, Hassanzadeh Kiabi N, Nadeau S, Porritt R, et al. Blimp-1 Functions as a Molecular Switch to Prevent Inflammatory Activity in Foxp3+RORγt+ Regulatory T Cells. Cell Rep. 2018;25:19-28.e5 pubmed publisher |
Tsutsui M, Hirase R, Miyamura S, Nagayasu K, Nakagawa T, Mori Y, et al. TRPM2 Exacerbates Central Nervous System Inflammation in Experimental Autoimmune Encephalomyelitis by Increasing Production of CXCL2 Chemokines. J Neurosci. 2018;38:8484-8495 pubmed publisher |
Chen J, Yang N, Liu H, Yao H, Wang J, Yang Y, et al. Immunological effects of a low-dose cytarabine, aclarubicin and granulocyte-colony stimulating factor priming regimen on a mouse leukemia model. Oncol Lett. 2018;16:3022-3028 pubmed publisher |
Heimesaat M, Escher U, Grunau A, Fiebiger U, Bereswill S. Peroral Low-Dose Toxoplasma gondii Infection of Human Microbiota-Associated Mice - A Subacute Ileitis Model to Unravel Pathogen-Host Interactions. Eur J Microbiol Immunol (Bp). 2018;8:53-61 pubmed publisher |
Cobbold S, Adams E, Howie D, Waldmann H. CD4+ T Cell Fate Decisions Are Stochastic, Precede Cell Division, Depend on GITR Co-Stimulation, and Are Associated With Uropodium Development. Front Immunol. 2018;9:1381 pubmed publisher |
Ziegler P, Bollrath J, Pallangyo C, Matsutani T, Canli O, De Oliveira T, et al. Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis. Cell. 2018;174:88-101.e16 pubmed publisher |
Wunderlich C, Ackermann P, Ostermann A, Adams Quack P, Vogt M, Tran M, et al. Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment. Nat Commun. 2018;9:1646 pubmed publisher |
Emmerson A, Trevelin S, Mongue Din H, Becker P, Ortiz C, Smyth L, et al. Nox2 in regulatory T cells promotes angiotensin II-induced cardiovascular remodeling. J Clin Invest. 2018;128:3088-3101 pubmed publisher |
Habib S, El Andaloussi A, Elmasry K, Handoussa A, Azab M, Elsawey A, et al. PDL-1 Blockade Prevents T Cell Exhaustion, Inhibits Autophagy, and Promotes Clearance of Leishmania donovani. Infect Immun. 2018;86: pubmed publisher |
Lopes N, Charaix J, Cedile O, Serge A, Irla M. Lymphotoxin α fine-tunes T cell clonal deletion by regulating thymic entry of antigen-presenting cells. Nat Commun. 2018;9:1262 pubmed publisher |
Kraakman M, Liu Q, Postigo Fernandez J, Ji R, Kon N, Larrea D, et al. PPAR? deacetylation dissociates thiazolidinedione's metabolic benefits from its adverse effects. J Clin Invest. 2018;128:2600-2612 pubmed publisher |
Lamothe R, Kolte P, Vo T, Ferrari J, Gelsinger T, Wong J, et al. Tolerogenic Nanoparticles Induce Antigen-Specific Regulatory T Cells and Provide Therapeutic Efficacy and Transferrable Tolerance against Experimental Autoimmune Encephalomyelitis. Front Immunol. 2018;9:281 pubmed publisher |
Chen D, Xie J, Fiskesund R, Dong W, Liang X, Lv J, et al. Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype. Nat Commun. 2018;9:873 pubmed publisher |
Ricca J, Oseledchyk A, Walther T, Liu C, Mangarin L, Merghoub T, et al. Pre-existing Immunity to Oncolytic Virus Potentiates Its Immunotherapeutic Efficacy. Mol Ther. 2018;26:1008-1019 pubmed publisher |
Alizadeh A, Santhosh K, Kataria H, Gounni A, Karimi Abdolrezaee S. Neuregulin-1 elicits a regulatory immune response following traumatic spinal cord injury. J Neuroinflammation. 2018;15:53 pubmed publisher |
Kornberg M, Smith M, Shirazi H, Calabresi P, Snyder S, Kim P. Bryostatin-1 alleviates experimental multiple sclerosis. Proc Natl Acad Sci U S A. 2018;115:2186-2191 pubmed publisher |
Liu Y, Sun L, Chen W, Chuai J, Shang Y, Zhang D, et al. Combined treatment with simvastatin and rapamycin attenuates cardiac allograft rejection through the regulation of T helper 17 and regulatory T cells. Exp Ther Med. 2018;15:1941-1949 pubmed publisher |
Yap J, Wirasinha R, Chan A, Howard D, Goodnow C, Daley S. Indirect presentation in the thymus limits naive and regulatory T-cell differentiation by promoting deletion of self-reactive thymocytes. Immunology. 2018;154:522-532 pubmed publisher |
Dar H, Singh A, Shukla P, Anupam R, Mondal R, Mishra P, et al. High dietary salt intake correlates with modulated Th17-Treg cell balance resulting in enhanced bone loss and impaired bone-microarchitecture in male mice. Sci Rep. 2018;8:2503 pubmed publisher |
Wei Y, Zhang Z, Wang F, Zhou S. Assessment of tumor growth factor-β1 neutralizing antibody in the treatment of allergic rhinitis and asthma. Exp Ther Med. 2018;15:649-656 pubmed publisher |
Hsieh W, Hsu T, Chang Y, Lai M. IL-6 receptor blockade corrects defects of XIAP-deficient regulatory T cells. Nat Commun. 2018;9:463 pubmed publisher |
Lu Y, Kim N, Jiang Y, Zhang H, Zheng D, Zhu F, et al. Cambogin suppresses dextran sulphate sodium-induced colitis by enhancing Treg cell stability and function. Br J Pharmacol. 2018;175:1085-1099 pubmed publisher |
Filley A, Henriquez M, Bhowmik T, Tewari B, Rao X, Wan J, et al. Immunologic and gene expression profiles of spontaneous canine oligodendrogliomas. J Neurooncol. 2018;137:469-479 pubmed publisher |
Jiao Y, Tan S, Xiong J. Proteomic changes of CD4+/CD25+/forkhead box p3+ regulatory T cells in a 30-day rat model of sepsis survival. Exp Ther Med. 2017;14:5619-5628 pubmed publisher |
Xie L, Zhong X, Liu D, Liu L, Xia Z. The effects of freeze-dried Ganoderma lucidum mycelia on a recurrent oral ulceration rat model. BMC Complement Altern Med. 2017;17:511 pubmed publisher |
Lu J, Liu X, Liao Y, Salazar F, Sun B, Jiang W, et al. Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression. Nat Commun. 2017;8:1811 pubmed publisher |
Palazon A, Tyrakis P, Macías D, Veliça P, Rundqvist H, Fitzpatrick S, et al. An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression. Cancer Cell. 2017;32:669-683.e5 pubmed publisher |
Liang Z, Zhang L, Su H, Luan R, Na N, Sun L, et al. MTOR signaling is essential for the development of thymic epithelial cells and the induction of central immune tolerance. Autophagy. 2017;: pubmed publisher |
Wang J, Xie T, Wang B, William W, Heymach J, El Naggar A, et al. PD-1 Blockade Prevents the Development and Progression of Carcinogen-Induced Oral Premalignant Lesions. Cancer Prev Res (Phila). 2017;10:684-693 pubmed publisher |
Kim H, Jang S, Lee W, Kim K, Sohn H, Hwang S, et al. PTEN drives Th17 cell differentiation by preventing IL-2 production. J Exp Med. 2017;214:3381-3398 pubmed publisher |
Li Y, Li H, Cao Y, Wu F, Ma W, Wang Y, et al. Placenta‑derived mesenchymal stem cells improve airway hyperresponsiveness and inflammation in asthmatic rats by modulating the Th17/Treg balance. Mol Med Rep. 2017;16:8137-8145 pubmed publisher |
Kwon H, Chen H, Mathis D, Benoist C. Different molecular complexes that mediate transcriptional induction and repression by FoxP3. Nat Immunol. 2017;18:1238-1248 pubmed publisher |
Minter M, Hinterleitner R, Meisel M, Zhang C, Leone V, Zhang X, et al. Antibiotic-induced perturbations in microbial diversity during post-natal development alters amyloid pathology in an aged APPSWE/PS1ΔE9 murine model of Alzheimer's disease. Sci Rep. 2017;7:10411 pubmed publisher |
Colpitts S, Kasper E, Keever A, Liljenberg C, Kirby T, Magori K, et al. A bidirectional association between the gut microbiota and CNS disease in a biphasic murine model of multiple sclerosis. Gut Microbes. 2017;8:561-573 pubmed publisher |
Sitrin J, Suto E, Wuster A, Eastham Anderson J, Kim J, Austin C, et al. The Ox40/Ox40 Ligand Pathway Promotes Pathogenic Th Cell Responses, Plasmablast Accumulation, and Lupus Nephritis in NZB/W F1 Mice. J Immunol. 2017;199:1238-1249 pubmed publisher |
Wang Y, Chen J, Chang C, Jen J, Huang T, Chen C, et al. Ubiquitination of tumor suppressor PML regulates prometastatic and immunosuppressive tumor microenvironment. J Clin Invest. 2017;127:2982-2997 pubmed publisher |
Son C, Bae J, Lee H, Yang K, Park Y. Enhancement of antitumor immunity by combination of anti-CTLA-4 antibody and radioimmunotherapy through the suppression of Tregs. Oncol Lett. 2017;13:3781-3786 pubmed publisher |
Maglioco A, Machuca D, Badano M, Nannini P, Camerano G, Costa H, et al. B cells inhibit the antitumor immunity against an established murine fibrosarcoma. Oncol Lett. 2017;13:3225-3232 pubmed publisher |
Kim K, Bae S, Capece T, Nedelkovska H, de Rubio R, Smrcka A, et al. Targeted calcium influx boosts cytotoxic T lymphocyte function in the tumour microenvironment. Nat Commun. 2017;8:15365 pubmed publisher |
Shigemoto Kuroda T, Oh J, Kim D, Jeong H, Park S, Lee H, et al. MSC-derived Extracellular Vesicles Attenuate Immune Responses in Two Autoimmune Murine Models: Type 1 Diabetes and Uveoretinitis. Stem Cell Reports. 2017;8:1214-1225 pubmed publisher |
Chen J, Zhang M, Zhou F, Wang J, Niu B, Zhang W. Immunological effects of vaccines combined with granulocyte colony-stimulating factor on a murine WEHI-3 leukemia model. Oncol Lett. 2017;13:2323-2329 pubmed publisher |
Li Y, Liu X, Duan W, Tian H, Zhu G, He H, et al. Batf3-dependent CD8?+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages. EBioMedicine. 2017;18:188-198 pubmed publisher |
Zhu F, Willette Brown J, Song N, Lomada D, Song Y, Xue L, et al. Autoreactive T Cells and Chronic Fungal Infection Drive Esophageal Carcinogenesis. Cell Host Microbe. 2017;21:478-493.e7 pubmed publisher |
Chien C, Yu H, Chen S, Chiang B. Characterization of c-Maf+Foxp3- Regulatory T Cells Induced by Repeated Stimulation of Antigen-Presenting B Cells. Sci Rep. 2017;7:46348 pubmed publisher |
Wang J, Perry C, Meeth K, Thakral D, Damsky W, Micevic G, et al. UV-induced somatic mutations elicit a functional T cell response in the YUMMER1.7 mouse melanoma model. Pigment Cell Melanoma Res. 2017;30:428-435 pubmed publisher |
Hu D, Wirasinha R, Goodnow C, Daley S. IL-2 prevents deletion of developing T-regulatory cells in the thymus. Cell Death Differ. 2017;24:1007-1016 pubmed publisher |
Liu Z, Ravindranathan R, Kalinski P, Guo Z, Bartlett D. Rational combination of oncolytic vaccinia virus and PD-L1 blockade works synergistically to enhance therapeutic efficacy. Nat Commun. 2017;8:14754 pubmed publisher |
Scharschmidt T, Vasquez K, Pauli M, Leitner E, Chu K, Truong H, et al. Commensal Microbes and Hair Follicle Morphogenesis Coordinately Drive Treg Migration into Neonatal Skin. Cell Host Microbe. 2017;21:467-477.e5 pubmed publisher |
Klein J, Moses K, Zelinskyy G, Sody S, Buer J, Lang S, et al. Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth. Nat Commun. 2017;8:14600 pubmed publisher |
Barthels C, Ogrinc A, Steyer V, Meier S, Simon F, Wimmer M, et al. CD40-signalling abrogates induction of RORγt+ Treg cells by intestinal CD103+ DCs and causes fatal colitis. Nat Commun. 2017;8:14715 pubmed publisher |
Komegae E, Souza T, Grund L, Lima C, Lopes Ferreira M. Multiple functional therapeutic effects of TnP: A small stable synthetic peptide derived from fish venom in a mouse model of multiple sclerosis. PLoS ONE. 2017;12:e0171796 pubmed publisher |
Li J, Jing J, Bai Y, Li Z, Xing R, Tan B, et al. SH479, a Betulinic Acid Derivative, Ameliorates Experimental Autoimmune Encephalomyelitis by Regulating the T Helper 17/Regulatory T Cell Balance. Mol Pharmacol. 2017;91:464-474 pubmed publisher |
Huang A, Peng D, Guo H, Ben Y, Zuo X, Wu F, et al. A human programmed death-ligand 1-expressing mouse tumor model for evaluating the therapeutic efficacy of anti-human PD-L1 antibodies. Sci Rep. 2017;7:42687 pubmed publisher |
Huang R, Francois A, McGray A, Miliotto A, Odunsi K. Compensatory upregulation of PD-1, LAG-3, and CTLA-4 limits the efficacy of single-agent checkpoint blockade in metastatic ovarian cancer. Oncoimmunology. 2017;6:e1249561 pubmed publisher |
Zamarin D, Holmgaard R, Ricca J, Plitt T, Palese P, Sharma P, et al. Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity. Nat Commun. 2017;8:14340 pubmed publisher |
Leech J, Lacey K, Mulcahy M, Medina E, McLoughlin R. IL-10 Plays Opposing Roles during Staphylococcus aureus Systemic and Localized Infections. J Immunol. 2017;198:2352-2365 pubmed publisher |
Zhang H, Qi Y, Yuan Y, Cai L, Xu H, Zhang L, et al. Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation. Sci Rep. 2017;7:41887 pubmed publisher |
Berlato C, Khan M, Schioppa T, Thompson R, Maniati E, Montfort A, et al. A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer. J Clin Invest. 2017;127:801-813 pubmed publisher |
Vander Lugt B, Riddell J, Khan A, Hackney J, Lesch J, DeVoss J, et al. Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation. J Cell Biol. 2017;216:779-792 pubmed publisher |
van Nieuwenhuijze A, Dooley J, Humblet Baron S, Sreenivasan J, Koenders M, Schlenner S, et al. Defective germinal center B-cell response and reduced arthritic pathology in microRNA-29a-deficient mice. Cell Mol Life Sci. 2017;74:2095-2106 pubmed publisher |
Cruz L, Hashemifar S, Wu C, Cho S, Nguyen D, Lin L, et al. Excessive expression of miR-27 impairs Treg-mediated immunological tolerance. J Clin Invest. 2017;127:530-542 pubmed publisher |
Blanquiceth Y, Rodríguez Perea A, Tabares Guevara J, Correa L, Sánchez M, Ramirez Pineda J, et al. Increase of Frequency and Modulation of Phenotype of Regulatory T Cells by Atorvastatin Is Associated with Decreased Lung Inflammatory Cell Infiltration in a Murine Model of Acute Allergic Asthma. Front Immunol. 2016;7:620 pubmed publisher |
Yun T, Lee J, Shim D, Choi J, Cheong C. Isolation and Characterization of Aortic Dendritic Cells and Lymphocytes in Atherosclerosis. Methods Mol Biol. 2017;1559:419-437 pubmed publisher |
Araujo L, Khim P, Mkhikian H, Mortales C, Demetriou M. Glycolysis and glutaminolysis cooperatively control T cell function by limiting metabolite supply to N-glycosylation. elife. 2017;6: pubmed publisher |
Engler J, Kursawe N, Solano M, Patas K, Wehrmann S, Heckmann N, et al. Glucocorticoid receptor in T cells mediates protection from autoimmunity in pregnancy. Proc Natl Acad Sci U S A. 2017;114:E181-E190 pubmed publisher |
Hayakawa M, Hayakawa H, Petrova T, Ritprajak P, Sutavani R, Jiménez Andrade G, et al. Loss of Functionally Redundant p38 Isoforms in T Cells Enhances Regulatory T Cell Induction. J Biol Chem. 2017;292:1762-1772 pubmed publisher |
Wang Z, Navarro Alvarez N, Shah J, Zhang H, Huang Q, Zheng Q, et al. Porcine Treg depletion with a novel diphtheria toxin-based anti-human CCR4 immunotoxin. Vet Immunol Immunopathol. 2016;182:150-158 pubmed publisher |
Ju X, Silveira P, Hsu W, Elgundi Z, Alingcastre R, Verma N, et al. The Analysis of CD83 Expression on Human Immune Cells Identifies a Unique CD83+-Activated T Cell Population. J Immunol. 2016;197:4613-4625 pubmed |
Marichal T, Gaudenzio N, El Abbas S, Sibilano R, Zurek O, Starkl P, et al. Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis. J Clin Invest. 2016;126:4497-4515 pubmed publisher |
Park K, Mikulski Z, Seo G, Andreyev A, Marcovecchio P, Blatchley A, et al. The transcription factor NR4A3 controls CD103+ dendritic cell migration. J Clin Invest. 2016;126:4603-4615 pubmed publisher |
Jirmo A, Daluege K, Happle C, Albrecht M, Dittrich A, Busse M, et al. IL-27 Is Essential for Suppression of Experimental Allergic Asthma by the TLR7/8 Agonist R848 (Resiquimod). J Immunol. 2016;197:4219-4227 pubmed |
Serr I, Fürst R, Ott V, Scherm M, Nikolaev A, Gökmen F, et al. miRNA92a targets KLF2 and the phosphatase PTEN signaling to promote human T follicular helper precursors in T1D islet autoimmunity. Proc Natl Acad Sci U S A. 2016;113:E6659-E6668 pubmed |
Starobinets H, Ye J, Broz M, Barry K, Goldsmith J, Marsh T, et al. Antitumor adaptive immunity remains intact following inhibition of autophagy and antimalarial treatment. J Clin Invest. 2016;126:4417-4429 pubmed publisher |
Makita N, Ishiguro J, Suzuki K, Nara F. Dichloroacetate induces regulatory T-cell differentiation and suppresses Th17-cell differentiation by pyruvate dehydrogenase kinase-independent mechanism. J Pharm Pharmacol. 2017;69:43-51 pubmed publisher |
Coursey T, Bian F, Zaheer M, Pflugfelder S, Volpe E, de Paiva C. Age-related spontaneous lacrimal keratoconjunctivitis is accompanied by dysfunctional T regulatory cells. Mucosal Immunol. 2017;10:743-756 pubmed publisher |
Federico G, Meister M, Mathow D, Heine G, Moldenhauer G, Popovic Z, et al. Tubular Dickkopf-3 promotes the development of renal atrophy and fibrosis. JCI Insight. 2016;1:e84916 pubmed publisher |
Bearoff F, del Rio R, Case L, Dragon J, Nguyen Vu T, Lin C, et al. Natural genetic variation profoundly regulates gene expression in immune cells and dictates susceptibility to CNS autoimmunity. Genes Immun. 2016;17:386-395 pubmed publisher |
Kumano K, Nishinakamura H, Mera T, Itoh T, Takahashi H, Fujiwara T, et al. Pretreatment of donor islets with papain improves allograft survival without systemic immunosuppression in mice. Islets. 2016;8:145-55 pubmed publisher |
Uhde A, Herder V, Akram Khan M, Ciurkiewicz M, Schaudien D, Teich R, et al. Viral Infection of the Central Nervous System Exacerbates Interleukin-10 Receptor Deficiency-Mediated Colitis in SJL Mice. PLoS ONE. 2016;11:e0161883 pubmed publisher |
Clever D, Roychoudhuri R, Constantinides M, Askenase M, Sukumar M, Klebanoff C, et al. Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche. Cell. 2016;166:1117-1131.e14 pubmed publisher |
Belinson H, Savage A, Fadrosh D, Kuo Y, Lin D, Valladares R, et al. Dual epithelial and immune cell function of Dvl1 regulates gut microbiota composition and intestinal homeostasis. JCI Insight. 2016;1: pubmed publisher |
Carow B, Gao Y, Coquet J, Reilly M, Rottenberg M. lck-Driven Cre Expression Alters T Cell Development in the Thymus and the Frequencies and Functions of Peripheral T Cell Subsets. J Immunol. 2016;197:2261-8 pubmed publisher |
Petrarca C, Clemente E, Amato V, Gatta A, Cortese S, Lamolinara A, et al. Vitamin D3 improves the effects of low dose Der p 2 allergoid treatment in Der p 2 sensitized BALB/c mice. Clin Mol Allergy. 2016;14:7 pubmed publisher |
Shi L, Fu T, Guan B, Chen J, Blando J, Allison J, et al. Interdependent IL-7 and IFN-? signalling in T-cell controls tumour eradication by combined ?-CTLA-4+?-PD-1 therapy. Nat Commun. 2016;7:12335 pubmed publisher |
Gölz G, Alter T, Bereswill S, Heimesaat M. The Immunopathogenic Potential of Arcobacter butzleri - Lessons from a Meta-Analysis of Murine Infection Studies. PLoS ONE. 2016;11:e0159685 pubmed publisher |
Parsa R, Lund H, Georgoudaki A, Zhang X, Ortlieb Guerreiro Cacais A, Grommisch D, et al. BAFF-secreting neutrophils drive plasma cell responses during emergency granulopoiesis. J Exp Med. 2016;213:1537-53 pubmed publisher |
Pietrocola F, Pol J, Vacchelli E, Rao S, Enot D, Baracco E, et al. Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance. Cancer Cell. 2016;30:147-160 pubmed publisher |
Stifter K, Schuster C, Schlosser M, Boehm B, Schirmbeck R. Exploring the induction of preproinsulin-specific Foxp3(+) CD4(+) Treg cells that inhibit CD8(+) T cell-mediated autoimmune diabetes by DNA vaccination. Sci Rep. 2016;6:29419 pubmed publisher |
Riedel A, Shorthouse D, Haas L, Hall B, Shields J. Tumor-induced stromal reprogramming drives lymph node transformation. Nat Immunol. 2016;17:1118-27 pubmed publisher |
Keil M, Sonner J, Lanz T, Oezen I, Bunse T, Bittner S, et al. General control non-derepressible 2 (GCN2) in T cells controls disease progression of autoimmune neuroinflammation. J Neuroimmunol. 2016;297:117-26 pubmed publisher |
Bereswill S, Alutis M, Grundmann U, Fischer A, Göbel U, Heimesaat M. Interleukin-18 Mediates Immune Responses to Campylobacter jejuni Infection in Gnotobiotic Mice. PLoS ONE. 2016;11:e0158020 pubmed publisher |
Gu L, Deng W, Sun X, Zhou H, Xu Q. Rapamycin ameliorates CCl4-induced liver fibrosis in mice through reciprocal regulation of the Th17/Treg cell balance. Mol Med Rep. 2016;14:1153-61 pubmed publisher |
Ruhland M, Loza A, Capietto A, Luo X, Knolhoff B, Flanagan K, et al. Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis. Nat Commun. 2016;7:11762 pubmed publisher |
Haddad C, Bhattacharya P, Alharshawi K, Marinelarena A, Kumar P, El Sayed O, et al. Age-dependent divergent effects of OX40L treatment on the development of diabetes in NOD mice. Autoimmunity. 2016;49:298-311 pubmed publisher |
Göbel K, Pankratz S, Asaridou C, Herrmann A, Bittner S, Merker M, et al. Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells. Nat Commun. 2016;7:11626 pubmed publisher |
Contreras F, Prado C, Gonzalez H, Franz D, Osorio Barrios F, Osorio F, et al. Dopamine Receptor D3 Signaling on CD4+ T Cells Favors Th1- and Th17-Mediated Immunity. J Immunol. 2016;196:4143-9 pubmed publisher |
Bähr A, Käser T, Kemter E, Gerner W, Kurome M, Baars W, et al. Ubiquitous LEA29Y Expression Blocks T Cell Co-Stimulation but Permits Sexual Reproduction in Genetically Modified Pigs. PLoS ONE. 2016;11:e0155676 pubmed publisher |
Kroon P, Gadiot J, Peeters M, Gasparini A, Deken M, Yagita H, et al. Concomitant targeting of programmed death-1 (PD-1) and CD137 improves the efficacy of radiotherapy in a mouse model of human BRAFV600-mutant melanoma. Cancer Immunol Immunother. 2016;65:753-63 pubmed publisher |
O Leary C, Riling C, Spruce L, Ding H, Kumar S, Deng G, et al. Ndfip-mediated degradation of Jak1 tunes cytokine signalling to limit expansion of CD4+ effector T cells. Nat Commun. 2016;7:11226 pubmed publisher |
Goldstein J, Burlion A, Zaragoza B, Sendeyo K, Polansky J, Huehn J, et al. Inhibition of the JAK/STAT Signaling Pathway in Regulatory T Cells Reveals a Very Dynamic Regulation of Foxp3 Expression. PLoS ONE. 2016;11:e0153682 pubmed publisher |
Du C, Duan Y, Wei W, Cai Y, Chai H, Lv J, et al. Kappa opioid receptor activation alleviates experimental autoimmune encephalomyelitis and promotes oligodendrocyte-mediated remyelination. Nat Commun. 2016;7:11120 pubmed publisher |
Yue Y, Li P, Song N, Li B, Li Z, Guo Y, et al. Genomic and immunologic factors associated with viral pathogenesis in a lethal EV71 infected neonatal mouse model. Mol Med Rep. 2016;13:4183-90 pubmed publisher |
Hashimoto A, Sato T, Iyama S, Yoshida M, Ibata S, Tatekoshi A, et al. Narrow-Band Ultraviolet B Phototherapy Ameliorates Acute Graft-Versus-Host Disease of the Intestine by Expansion of Regulatory T Cells. PLoS ONE. 2016;11:e0152823 pubmed publisher |
Martin B, Wang C, Zhang C, Kang Z, Gulen M, Zepp J, et al. T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitis. Nat Immunol. 2016;17:583-92 pubmed publisher |
Feng Z, Jensen S, Messenheimer D, Farhad M, Neuberger M, Bifulco C, et al. Multispectral Imaging of T and B Cells in Murine Spleen and Tumor. J Immunol. 2016;196:3943-50 pubmed publisher |
Gossmann J, Stolte M, Lohoff M, Yu P, Moll R, Finkernagel F, et al. A Gain-Of-Function Mutation in the Plcg2 Gene Protects Mice from Helicobacter felis-Induced Gastric MALT Lymphoma. PLoS ONE. 2016;11:e0150411 pubmed publisher |
Frodermann V, Van Duijn J, van Puijvelde G, van Santbrink P, Lagraauw H, de Vries M, et al. Heat-killed Staphylococcus aureus reduces atherosclerosis by inducing anti-inflammatory macrophages. J Intern Med. 2016;279:592-605 pubmed publisher |
Bulla R, Tripodo C, Rami D, Ling G, Agostinis C, Guarnotta C, et al. C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation. Nat Commun. 2016;7:10346 pubmed publisher |
Luo C, Liao W, Dadi S, Toure A, Li M. Graded Foxo1 activity in Treg cells differentiates tumour immunity from spontaneous autoimmunity. Nature. 2016;529:532-6 pubmed publisher |
Everts B, Tussiwand R, Dreesen L, Fairfax K, Huang S, Smith A, et al. Migratory CD103+ dendritic cells suppress helminth-driven type 2 immunity through constitutive expression of IL-12. J Exp Med. 2016;213:35-51 pubmed publisher |
Wu L, Li N, Zhang M, Xue S, Cassady K, Lin Q, et al. MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice. Proc Natl Acad Sci U S A. 2015;112:15994-9 pubmed publisher |
Jabara H, Boyden S, Chou J, Ramesh N, Massaad M, Benson H, et al. A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency. Nat Genet. 2016;48:74-8 pubmed publisher |
Carrascal J, Carrillo J, Arpa B, Egia Mendikute L, Rosell Mases E, Pujol Autonell I, et al. B-cell anergy induces a Th17 shift in a novel B lymphocyte transgenic NOD mouse model, the 116C-NOD mouse. Eur J Immunol. 2016;46:593-608 pubmed publisher |
Brand R, Stottlemyer J, Cline R, Donahue C, Behari J, Falo L. Skin Immunization Obviates Alcohol-Related Immune Dysfunction. Biomolecules. 2015;5:3009-28 pubmed publisher |
Finkin S, Yuan D, Stein I, Taniguchi K, Weber A, Unger K, et al. Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma. Nat Immunol. 2015;16:1235-44 pubmed publisher |
Patel M, Jacobson B, Ji Y, Drees J, Tang S, Xiong K, et al. Vesicular stomatitis virus expressing interferon-β is oncolytic and promotes antitumor immune responses in a syngeneic murine model of non-small cell lung cancer. Oncotarget. 2015;6:33165-77 pubmed publisher |
Zanvit P, Konkel J, Jiao X, Kasagi S, Zhang D, Wu R, et al. Antibiotics in neonatal life increase murine susceptibility to experimental psoriasis. Nat Commun. 2015;6:8424 pubmed publisher |
Gölz G, Karadas G, Alutis M, Fischer A, Kühl A, Breithaupt A, et al. Arcobacter butzleri Induce Colonic, Extra-Intestinal and Systemic Inflammatory Responses in Gnotobiotic IL-10 Deficient Mice in a Strain-Dependent Manner. PLoS ONE. 2015;10:e0139402 pubmed publisher |
Zhang L, Reckling S, Dean G. Phenotypic and functional analysis of CD1a+ dendritic cells from cats chronically infected with feline immunodeficiency virus. Comp Immunol Microbiol Infect Dis. 2015;42:53-9 pubmed publisher |
Guo A, He D, Xu H, Geng C, Zhao J. Promotion of regulatory T cell induction by immunomodulatory herbal medicine licorice and its two constituents. Sci Rep. 2015;5:14046 pubmed publisher |
Roberts R, Eitas T, Byrne J, Johnson B, Short P, McKinnon K, et al. Towards programming immune tolerance through geometric manipulation of phosphatidylserine. Biomaterials. 2015;72:1-10 pubmed publisher |
Baruch K, Rosenzweig N, Kertser A, Deczkowska A, Sharif A, Spinrad A, et al. Breaking immune tolerance by targeting Foxp3(+) regulatory T cells mitigates Alzheimer's disease pathology. Nat Commun. 2015;6:7967 pubmed publisher |
Mori H, Soonsawad P, Schuetter L, Chen Q, Hubbard N, Cardiff R, et al. Introduction of Zinc-salt Fixation for Effective Detection of Immune Cell-related Markers by Immunohistochemistry. Toxicol Pathol. 2015;43:883-9 pubmed publisher |
Khan I, Perrard X, Brunner G, Lui H, Sparks L, Smith S, et al. Intermuscular and perimuscular fat expansion in obesity correlates with skeletal muscle T cell and macrophage infiltration and insulin resistance. Int J Obes (Lond). 2015;39:1607-18 pubmed publisher |
Liao J, Ovenell K, Curtis E, Cecil D, Koehnlein M, Rastetter L, et al. Preservation of tumor-host immune interactions with luciferase-tagged imaging in a murine model of ovarian cancer. J Immunother Cancer. 2015;3:16 pubmed publisher |
Reis B, Lee K, Fanok M, Mascaraque C, Amoury M, Cohn L, et al. Leptin receptor signaling in T cells is required for Th17 differentiation. J Immunol. 2015;194:5253-60 pubmed publisher |
Kreiter S, Vormehr M, van de Roemer N, Diken M, Löwer M, Diekmann J, et al. Mutant MHC class II epitopes drive therapeutic immune responses to cancer. Nature. 2015;520:692-6 pubmed publisher |
Pratama A, Srivastava M, Williams N, Papa I, Lee S, Dinh X, et al. MicroRNA-146a regulates ICOS-ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres. Nat Commun. 2015;6:6436 pubmed publisher |
Wang L, Liu Y, Han R, Beier U, Bhatti T, Akimova T, et al. FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3. J Clin Invest. 2015;125:1111-23 pubmed publisher |
Jing W, Gershan J, Weber J, Tlomak D, McOlash L, Sabatos Peyton C, et al. Combined immune checkpoint protein blockade and low dose whole body irradiation as immunotherapy for myeloma. J Immunother Cancer. 2015;3:2 pubmed publisher |
Hefetz Sela S, Stein I, Klieger Y, Porat R, Sade Feldman M, Zreik F, et al. Acquisition of an immunosuppressive protumorigenic macrophage phenotype depending on c-Jun phosphorylation. Proc Natl Acad Sci U S A. 2014;111:17582-7 pubmed publisher |
Andersson K, Svensson M, Erlandsson M, Jonsson I, Bokarewa M. Down-regulation of survivin alleviates experimental arthritis. J Leukoc Biol. 2015;97:135-45 pubmed publisher |
Heimesaat M, Dunay I, Schulze S, Fischer A, Grundmann U, Alutis M, et al. Pituitary adenylate cyclase-activating polypeptide ameliorates experimental acute ileitis and extra-intestinal sequelae. PLoS ONE. 2014;9:e108389 pubmed publisher |
Bertin S, Lozano Ruiz B, Bachiller V, GarcÃa MartÃnez I, Herdman S, Zapater P, et al. Dual-specificity phosphatase 6 regulates CD4+ T-cell functions and restrains spontaneous colitis in IL-10-deficient mice. Mucosal Immunol. 2015;8:505-15 pubmed publisher |
Dai M, Yip Y, Hellstrom I, Hellstrom K. Curing mice with large tumors by locally delivering combinations of immunomodulatory antibodies. Clin Cancer Res. 2015;21:1127-38 pubmed publisher |
Heimesaat M, Dunay I, Alutis M, Fischer A, Möhle L, Göbel U, et al. Nucleotide-oligomerization-domain-2 affects commensal gut microbiota composition and intracerebral immunopathology in acute Toxoplasma gondii induced murine ileitis. PLoS ONE. 2014;9:e105120 pubmed publisher |
Penaloza MacMaster P, Kamphorst A, Wieland A, Araki K, Iyer S, West E, et al. Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection. J Exp Med. 2014;211:1905-18 pubmed publisher |
El Zaatari M, Chang Y, Zhang M, Franz M, Shreiner A, McDermott A, et al. Tryptophan catabolism restricts IFN-?-expressing neutrophils and Clostridium difficile immunopathology. J Immunol. 2014;193:807-16 pubmed publisher |
Dang S, Xu H, Xu C, Cai W, Li Q, Cheng Y, et al. Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis. Autophagy. 2014;10:1301-15 pubmed publisher |
Xu C, Fillmore C, Koyama S, Wu H, Zhao Y, Chen Z, et al. Loss of Lkb1 and Pten leads to lung squamous cell carcinoma with elevated PD-L1 expression. Cancer Cell. 2014;25:590-604 pubmed publisher |
Breuer J, Schwab N, Schneider Hohendorf T, Marziniak M, Mohan H, Bhatia U, et al. Ultraviolet B light attenuates the systemic immune response in central nervous system autoimmunity. Ann Neurol. 2014;75:739-58 pubmed publisher |
Zhang H, Chin A. Role of Rip2 in development of tumor-infiltrating MDSCs and bladder cancer metastasis. PLoS ONE. 2014;9:e94793 pubmed publisher |
Arvey A, van der Veeken J, Samstein R, Feng Y, Stamatoyannopoulos J, Rudensky A. Inflammation-induced repression of chromatin bound by the transcription factor Foxp3 in regulatory T cells. Nat Immunol. 2014;15:580-587 pubmed publisher |
Nagashima H, Okuyama Y, Asao A, Kawabe T, Yamaki S, Nakano H, et al. The adaptor TRAF5 limits the differentiation of inflammatory CD4(+) T cells by antagonizing signaling via the receptor for IL-6. Nat Immunol. 2014;15:449-56 pubmed publisher |
León B, Bradley J, Lund F, Randall T, Ballesteros Tato A. FoxP3+ regulatory T cells promote influenza-specific Tfh responses by controlling IL-2 availability. Nat Commun. 2014;5:3495 pubmed publisher |
Heimesaat M, Lugert R, Fischer A, Alutis M, Kuhl A, Zautner A, et al. Impact of Campylobacter jejuni cj0268c knockout mutation on intestinal colonization, translocation, and induction of immunopathology in gnotobiotic IL-10 deficient mice. PLoS ONE. 2014;9:e90148 pubmed publisher |
Liu H, Liu Z, Chao H, Li Z, Song Z, Yang Y, et al. High-dose interferon-? promotes abortion in mice by suppressing Treg and Th17 polarization. J Interferon Cytokine Res. 2014;34:394-403 pubmed publisher |
Zanello G, Goethel A, Forster K, Geddes K, Philpott D, Croitoru K. Nod2 activates NF-kB in CD4+ T cells but its expression is dispensable for T cell-induced colitis. PLoS ONE. 2013;8:e82623 pubmed publisher |
Wang S, Wu B, Xue J, Wang M, Chen R, Wang B. Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge. Hum Vaccin Immunother. 2014;10:461-8 pubmed publisher |
Bandini S, Curcio C, Macagno M, Quaglino E, Arigoni M, Lanzardo S, et al. Early onset and enhanced growth of autochthonous mammary carcinomas in C3-deficient Her2/neu transgenic mice. Oncoimmunology. 2013;2:e26137 pubmed |
Gonzalez J, Mouttalib S, Delage C, Calise D, Maoret J, Pradere J, et al. Dual effect of chemokine CCL7/MCP-3 in the development of renal tubulointerstitial fibrosis. Biochem Biophys Res Commun. 2013;438:257-63 pubmed publisher |
Jianjun Yang -, Zhang R, Lu G, Shen Y, Peng L, Zhu C, et al. T cell–derived inducible nitric oxide synthase switches off Th17 cell differentiation. J Exp Med. 2013;210:1447-62 pubmed |
Radulovic K, Rossini V, Manta C, Holzmann K, Kestler H, Niess J. The early activation marker CD69 regulates the expression of chemokines and CD4 T cell accumulation in intestine. PLoS ONE. 2013;8:e65413 pubmed publisher |
Jia W, Cao L, Yang S, Dong H, Zhang Y, Wei H, et al. Regulatory T cells are protective in systemic inflammation response syndrome induced by zymosan in mice. PLoS ONE. 2013;8:e64397 pubmed publisher |
Graham J, Zhang X, Goodman A, Pothoven K, Houlihan J, Wang S, et al. PLG scaffold delivered antigen-specific regulatory T cells induce systemic tolerance in autoimmune diabetes. Tissue Eng Part A. 2013;19:1465-75 pubmed publisher |
Tsiperson V, Gruber R, Goldberg M, JORDAN A, Weinger J, Macian F, et al. Suppression of inflammatory responses during myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis is regulated by AKT3 signaling. J Immunol. 2013;190:1528-39 pubmed publisher |
Reis B, Rogoz A, Costa Pinto F, Taniuchi I, Mucida D. Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4? T cell immunity. Nat Immunol. 2013;14:271-80 pubmed publisher |
Wan W, Lionakis M, Liu Q, Roffe E, Murphy P. Genetic deletion of chemokine receptor Ccr7 exacerbates atherogenesis in ApoE-deficient mice. Cardiovasc Res. 2013;97:580-8 pubmed publisher |
Nguyen L, Fifis T, Malcontenti Wilson C, Chan L, Costa P, Nikfarjam M, et al. Spatial morphological and molecular differences within solid tumors may contribute to the failure of vascular disruptive agent treatments. BMC Cancer. 2012;12:522 pubmed publisher |
Mineharu Y, Muhammad A, Yagiz K, Candolfi M, Kroeger K, Xiong W, et al. Gene therapy-mediated reprogramming tumor infiltrating T cells using IL-2 and inhibiting NF-κB signaling improves the efficacy of immunotherapy in a brain cancer model. Neurotherapeutics. 2012;9:827-43 pubmed publisher |
Fu W, Ergun A, Lu T, Hill J, Haxhinasto S, Fassett M, et al. A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells. Nat Immunol. 2012;13:972-80 pubmed publisher |
Wang Y, Zheng Z, Wang Y, Liu J, Li N, Hu X, et al. Role of donor-specific regulatory T cells in long-term acceptance of rat hind limb allograft. PLoS ONE. 2012;7:e43825 pubmed publisher |
Khalili S, Liu Y, Kornete M, Roescher N, Kodama S, Peterson A, et al. Mesenchymal stromal cells improve salivary function and reduce lymphocytic infiltrates in mice with Sjögren's-like disease. PLoS ONE. 2012;7:e38615 pubmed publisher |
Göbel K, Bittner S, Melzer N, Pankratz S, Dreykluft A, Schuhmann M, et al. CD4(+) CD25(+) FoxP3(+) regulatory T cells suppress cytotoxicity of CD8(+) effector T cells: implications for their capacity to limit inflammatory central nervous system damage at the parenchymal level. J Neuroinflammation. 2012;9:41 pubmed publisher |
Riella L, Liu T, Yang J, Chock S, Shimizu T, Mfarrej B, et al. Deleterious effect of CTLA4-Ig on a Treg-dependent transplant model. Am J Transplant. 2012;12:846-55 pubmed publisher |
Wantia N, Rodriguez N, Cirl C, Ertl T, Dürr S, Layland L, et al. Toll-like receptors 2 and 4 regulate the frequency of IFN?-producing CD4+ T-cells during pulmonary infection with Chlamydia pneumoniae. PLoS ONE. 2011;6:e26101 pubmed publisher |
Mathes D, Hwang B, Graves S, Edwards J, Chang J, Storer B, et al. Tolerance to vascularized composite allografts in canine mixed hematopoietic chimeras. Transplantation. 2011;92:1301-8 pubmed publisher |
McPhee C, Sproule T, Shin D, Bubier J, Schott W, Steinbuck M, et al. MHC class I family proteins retard systemic lupus erythematosus autoimmunity and B cell lymphomagenesis. J Immunol. 2011;187:4695-704 pubmed publisher |
Bereswill S, Fischer A, Plickert R, Haag L, Otto B, Kuhl A, et al. Novel murine infection models provide deep insights into the "ménage à trois" of Campylobacter jejuni, microbiota and host innate immunity. PLoS ONE. 2011;6:e20953 pubmed publisher |
Liu J, Zhang N, Li Q, Zhang W, Ke F, Leng Q, et al. Tumor-associated macrophages recruit CCR6+ regulatory T cells and promote the development of colorectal cancer via enhancing CCL20 production in mice. PLoS ONE. 2011;6:e19495 pubmed publisher |
Capurso N, Look M, Jeanbart L, Nowyhed H, Abraham C, Craft J, et al. Development of a nanoparticulate formulation of retinoic acid that suppresses Th17 cells and upregulates regulatory T cells. Self Nonself. 2010;1:335-340 pubmed |
Li X, Kostareli E, Suffner J, Garbi N, Hämmerling G. Efficient Treg depletion induces T-cell infiltration and rejection of large tumors. Eur J Immunol. 2010;40:3325-35 pubmed publisher |
Boenisch O, D Addio F, Watanabe T, Elyaman W, Magee C, Yeung M, et al. TIM-3: a novel regulatory molecule of alloimmune activation. J Immunol. 2010;185:5806-19 pubmed publisher |
EGHTESAD S, Zheng H, Nakai H, Epperly M, Clemens P. Effects of irradiating adult mdx mice before full-length dystrophin cDNA transfer on host anti-dystrophin immunity. Gene Ther. 2010;17:1181-90 pubmed publisher |
Veltman J, Lambers M, van Nimwegen M, de Jong S, Hendriks R, Hoogsteden H, et al. Low-dose cyclophosphamide synergizes with dendritic cell-based immunotherapy in antitumor activity. J Biomed Biotechnol. 2010;2010:798467 pubmed publisher |
Grimm M, Gasser M, Bueter M, Strehl J, Wang J, Nichiporuk E, et al. Evaluation of immunological escape mechanisms in a mouse model of colorectal liver metastases. BMC Cancer. 2010;10:82 pubmed publisher |
Setiady Y, Coccia J, Park P. In vivo depletion of CD4+FOXP3+ Treg cells by the PC61 anti-CD25 monoclonal antibody is mediated by FcgammaRIII+ phagocytes. Eur J Immunol. 2010;40:780-6 pubmed publisher |
Hancock W, Ozkaynak E. Three distinct domains contribute to nuclear transport of murine Foxp3. PLoS ONE. 2009;4:e7890 pubmed publisher |
Marks B, Nowyhed H, Choi J, Poholek A, Odegard J, Flavell R, et al. Thymic self-reactivity selects natural interleukin 17-producing T cells that can regulate peripheral inflammation. Nat Immunol. 2009;10:1125-32 pubmed publisher |
Perisić M, Arsenović Ranin N, Pilipovic I, Kosec D, Pesic V, Radojevic K, et al. Role of ovarian hormones in age-associated thymic involution revisited. Immunobiology. 2010;215:275-93 pubmed publisher |
Chen C, Rowell E, Thomas R, Hancock W, Wells A. Transcriptional regulation by Foxp3 is associated with direct promoter occupancy and modulation of histone acetylation. J Biol Chem. 2006;281:36828-34 pubmed |
