This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD140a (PDGFRA) Monoclonal Antibody (APA5), Super Bright 702, eBioscience
catalog :
67-1401-80
quantity :
25 µg
price :
US 161
clonality :
monoclonal
host :
rat
conjugate :
Super Bright 702
clone name :
APA5
reactivity :
mouse
application :
flow cytometry
citations: 8
Reference
Vu T, Takechi M, Shimizu M, Kitazawa T, Higashiyama H, Iwase A, et al. Dlx5-augmentation in neural crest cells reveals early development and differentiation potential of mouse apical head mesenchyme. Sci Rep. 2021;11:2092 pubmed publisher
Redente E, Chakraborty S, Sajuthi S, Black B, Edelman B, Seibold M, et al. Loss of Fas signaling in fibroblasts impairs homeostatic fibrosis resolution and promotes persistent pulmonary fibrosis. JCI Insight. 2020;6: pubmed publisher
Wu R, Ma F, Tosevska A, Farrell C, Pellegrini M, Deb A. Cardiac fibroblast proliferation rates and collagen expression mature early and are unaltered with advancing age. JCI Insight. 2020;5: pubmed publisher
Kondo J, Huh W, Franklin J, Heinrich M, Rubin B, Coffey R. A smooth muscle-derived, Braf-driven mouse model of gastrointestinal stromal tumor (GIST): evidence for an alternative GIST cell-of-origin. J Pathol. 2020;252:441-450 pubmed publisher
Falero Perez J, Sheibani N, Sorenson C. Bim expression modulates the pro-inflammatory phenotype of retinal astroglial cells. PLoS ONE. 2020;15:e0232779 pubmed publisher
Vila Ellis L, Cain M, Hutchison V, Flodby P, Crandall E, Borok Z, et al. Epithelial Vegfa Specifies a Distinct Endothelial Population in the Mouse Lung. Dev Cell. 2020;52:617-630.e6 pubmed publisher
Holland J, Sorrell J, Yates E, Smith K, Arbabi S, Arnold M, et al. A Brain-Melanocortin-Vagus Axis Mediates Adipose Tissue Expansion Independently of Energy Intake. Cell Rep. 2019;27:2399-2410.e6 pubmed publisher
Huang X, Feng T, Jiang Z, Meng J, Kou S, Lu Z, et al. Dual lineage tracing identifies intermediate mesenchymal stage for endocardial contribution to fibroblasts, coronary mural cells, and adipocytes. J Biol Chem. 2019;294:8894-8906 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD140a (PDGFRA) Monoclonal Antibody (APA5), Super Bright 702, eBioscience
Catalog # :
67-1401-80
Quantity :
25 µg
Price :
US 161
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 1.0 µg/test
Species :
Mouse
Clone :
APA5
Isotype :
IgG2a, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1.0 µg/test
Aliases :
AI115593; alpha platelet-derived growth factor receptor; Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha); alpha-type platelet-derived growth factor receptor; APDGFR; CD140 antigen-like family member A; CD140A; CD140a antigen; GAS9; MGC74795; OTTHUMP00000218656; PDGF A-chain; PDGF alpha chain; PDGF Receptor alpha; PDGF subunit A; PDGF-1; PDGFACE; PDGFR2; Pdgfr-2; PDGFRA; pdgfr-a; PDGFRA/BCR fusion; PDGF-R-alpha; PDGFR-alpha; platelet derived growth factor receptor alpha; platelet derived growth factor receptor, alpha polypeptide; platelet-derived growth factor alpha receptor; Platelet-derived growth factor receptor 2; platelet-derived growth factor receptor alpha; platelet-derived growth factor receptor, alpha polypeptide; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein; RHEPDGFRA
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA