This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD117 (c-Kit) Monoclonal Antibody (2B8), Super Bright 702, eBioscience™
catalog :
67-1171-80
quantity :
25µg
price :
US 164
clonality :
monoclonal
host :
rat
conjugate :
Super Bright 702
clone name :
2B8
reactivity :
mouse, swine
application :
flow cytometry
product information
Product Type :
Antibody
Product Name :
CD117 (c-Kit) Monoclonal Antibody (2B8), Super Bright 702, eBioscience™
Catalog # :
67-1171-80
Quantity :
25µg
Price :
US 164
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse, Porcine
Applications :
Flow Cytometry: 0.125 µg/test
Species :
Mouse, Porcine
Clone :
2B8
Isotype :
IgG2b, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
c-Kit, also known as CD117 and stem cell factor receptor, is a 145 kDa transmembrane tyrosine kinase encoded by the c-Kit proto-oncogene. c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, and activation. c-Kit mutations correlate with tumor growth and progression in a variety of cancers including mast cell disease, gastrointestinal stromal tumor, acute myeloid leukemia, Ewing sarcoma, and lung cancer. Phosphorylation at tyrosine 703 of c-Kit allows binding of Grb2 and activation of the Ras-Raf-ERK1 and 2 signaling pathway.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.125 µg/test
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA