MHC Class II (I-A/I-E) Monoclonal Antibody (M5/114.15.2), Super Bright 645, eBioscience™ | Invitrogen 64-5321-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MHC Class II (I-A/I-E) Monoclonal Antibody (M5/114.15.2), Super Bright 645, eBioscience™

catalog :

64-5321-82

quantity :

100 µg

price :

336 USD

clonality :

monoclonal

host :

rat

conjugate :

Super Bright 645

clone name :

M5/114.15.2

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 7

Reference
van Nieuwenhuijze A, Dooley J, Humblet Baron S, Sreenivasan J, Koenders M, Schlenner S, et al. Defective germinal center B-cell response and reduced arthritic pathology in microRNA-29a-deficient mice. Cell Mol Life Sci. 2017;74:2095-2106 pubmed publisher
Marichal T, Gaudenzio N, El Abbas S, Sibilano R, Zurek O, Starkl P, et al. Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis. J Clin Invest. 2016;126:4497-4515 pubmed publisher
Kimura T, Nada S, Takegahara N, Okuno T, Nojima S, Kang S, et al. Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals. Nat Commun. 2016;7:13130 pubmed publisher
Hoegl S, Ehrentraut H, Brodsky K, Victorino F, Golden Mason L, Eltzschig H, et al. NK cells regulate CXCR2+ neutrophil recruitment during acute lung injury. J Leukoc Biol. 2017;101:471-480 pubmed publisher
Ruhland M, Loza A, Capietto A, Luo X, Knolhoff B, Flanagan K, et al. Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis. Nat Commun. 2016;7:11762 pubmed publisher
Göbel K, Pankratz S, Asaridou C, Herrmann A, Bittner S, Merker M, et al. Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells. Nat Commun. 2016;7:11626 pubmed publisher
Tacke R, Hilgendorf I, Garner H, Waterborg C, Park K, Nowyhed H, et al. The transcription factor NR4A1 is essential for the development of a novel macrophage subset in the thymus. Sci Rep. 2015;5:10055 pubmed publisher

product information

Product Type :

Antibody

Product Name :

MHC Class II (I-A/I-E) Monoclonal Antibody (M5/114.15.2), Super Bright 645, eBioscience™

Catalog # :

64-5321-82

Quantity :

100 µg

Price :

336 USD

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.125 µg/test

Species :

Mouse

Clone :

M5/114.15.2

Isotype :

IgG2b, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.125 µg/test

Aliases :

Abeta; AI845868; cell surface glycoprotein; H-2 class II histocompatibility antigen, A beta chain; H-2 class II histocompatibility antigen, I-E beta chain; H-2Ab; H2-Ab; H2-Ab1; H2Eb; H-2Eb; H2-Eb1; H2-iabeta; histocompatibility 2, class II antigen A, beta 1; histocompatibility 2, class II antigen E beta; Ia2; Ia-2; Ia4; Ia-4; IAb; I-Ab; I-Abeta; I-Ad; I-Aq; I-E beta MHC class II; I-Ed; I-Ek; major histocompatibility complex class II beta chain; major histocompatibility complex H-2E beta chain; MHC class 2; MHC class II antigen A beta; MHC class II H2-IA-beta-psi; MHC class II IE-b; MHC H2-IE-beta cell surface glycoprotein; response to metastatic cancers 1; Rmcs1

more info or order :

Invitrogen product webpage