F4/80 Monoclonal Antibody (BM8), Super Bright 645, eBioscience | Invitrogen 64-4801-80 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

F4/80 Monoclonal Antibody (BM8), Super Bright 645, eBioscience

catalog :

64-4801-80

quantity :

25 µg

price :

US 159

clonality :

monoclonal

host :

rat

conjugate :

Super Bright 645

clone name :

BM8

reactivity :

mouse

application :

flow cytometry

citations: 26

Reference
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Robinson E, Covarrubias S, Zhou S, Carpenter S. Generation and utilization of a HEK-293T murine GM-CSF expressing cell line. PLoS ONE. 2021;16:e0249117 pubmed publisher
Gula G, Ruminski S, Niderla Bielinska J, Jasińska A, Kiernozek E, Jankowska Steifer E, et al. Potential functions of embryonic cardiac macrophages in angiogenesis, lymphangiogenesis and extracellular matrix remodeling. Histochem Cell Biol. 2021;155:117-132 pubmed publisher
Jin J, Wang T, Park W, Li W, Kim W, Park S, et al. Inhibition of Yes-Associated Protein by Verteporfin Ameliorates Unilateral Ureteral Obstruction-Induced Renal Tubulointerstitial Inflammation and Fibrosis. Int J Mol Sci. 2020;21: pubmed publisher
Pavlovic N, Kopsida M, Gerwins P, Heindryckx F. Inhibiting P2Y12 in Macrophages Induces Endoplasmic Reticulum Stress and Promotes an Anti-Tumoral Phenotype. Int J Mol Sci. 2020;21: pubmed publisher
Schilke R, Blackburn C, Rao S, Krzywanski D, Finck B, Woolard M. Macrophage-Associated Lipin-1 Promotes β-Oxidation in Response to Proresolving Stimuli. Immunohorizons. 2020;4:659-669 pubmed publisher
Moore J, Wier C, Lemmerman L, Ortega Pineda L, Dodd D, Lawrence W, et al. Nanochannel-Based Poration Drives Benign and Effective Nonviral Gene Delivery to Peripheral Nerve Tissue. Adv Biosyst. 2020;4:e2000157 pubmed publisher
Krenacs T, Meggyeshazi N, Forika G, Kiss E, Hamar P, Székely T, et al. Modulated Electro-Hyperthermia-Induced Tumor Damage Mechanisms Revealed in Cancer Models. Int J Mol Sci. 2020;21: pubmed publisher
Brett J, Arjona M, Ikeda M, Quarta M, de Morrée A, Egner I, et al. Exercise rejuvenates quiescent skeletal muscle stem cells in old mice through restoration of Cyclin D1. Nat Metab. 2020;2:307-317 pubmed publisher
Lu C, Shiau A, Su B, Hsu T, Wang C, Su Y, et al. Oct4 promotes M2 macrophage polarization through upregulation of macrophage colony-stimulating factor in lung cancer. J Hematol Oncol. 2020;13:62 pubmed publisher
Zhao S, Liu H, Chen J, Qian D, Kong F, Jie J, et al. Macrophage GIT1 Contributes to Bone Regeneration by Regulating Inflammatory Responses in an ERK/NRF2-Dependent Way. J Bone Miner Res. 2020;: pubmed publisher
Shiuan E, Inala A, Wang S, Song W, Youngblood V, Chen J, et al. Host deficiency in ephrin-A1 inhibits breast cancer metastasis. F1000Res. 2020;9:217 pubmed publisher
Wise L, Stuart G, Jones N, Fleming S, Mercer A. Orf Virus IL-10 and VEGF-E Act Synergistically to Enhance Healing of Cutaneous Wounds in Mice. J Clin Med. 2020;9: pubmed publisher
Bottek J, Soun C, Lill J, Dixit A, Thiebes S, Beerlage A, et al. Spatial proteomics revealed a CX3CL1-dependent crosstalk between the urothelium and relocated macrophages through IL-6 during an acute bacterial infection in the urinary bladder. Mucosal Immunol. 2020;13:702-714 pubmed publisher
Li G, Wang M, Caulk A, Cilfone N, Gujja S, Qin L, et al. Chronic mTOR activation induces a degradative smooth muscle cell phenotype. J Clin Invest. 2020;130:1233-1251 pubmed publisher
Lee D, Lim J, Cho K. Differential Activation of Macrophages Based on Their Environment in Advanced Age. Chonnam Med J. 2020;56:12-19 pubmed publisher
Blagih J, Zani F, Chakravarty P, Hennequart M, Pilley S, Hobor S, et al. Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses. Cell Rep. 2020;30:481-496.e6 pubmed publisher
Chen M, Lu P, Ma Q, Cao Y, Chen N, Li W, et al. CTNNB1/β-catenin dysfunction contributes to adiposity by regulating the cross-talk of mature adipocytes and preadipocytes. Sci Adv. 2020;6:eaax9605 pubmed publisher
Kurelac I, Abarrategi A, Ragazzi M, Iommarini L, Umesh Ganesh N, Snoeks T, et al. A Humanized Bone Niche Model Reveals Bone Tissue Preservation Upon Targeting Mitochondrial Complex I in Pseudo-Orthotopic Osteosarcoma. J Clin Med. 2019;8: pubmed publisher
Kusano T, Ehirchiou D, Matsumura T, Chobaz V, Nasi S, Castelblanco M, et al. Targeted knock-in mice expressing the oxidase-fixed form of xanthine oxidoreductase favor tumor growth. Nat Commun. 2019;10:4904 pubmed publisher
Heimesaat M, Mrazek K, Bereswill S. Murine Fecal Microbiota Transplantation Alleviates Intestinal and Systemic Immune Responses in Campylobacter jejuni Infected Mice Harboring a Human Gut Microbiota. Front Immunol. 2019;10:2272 pubmed publisher
Escolano A, Gristick H, Abernathy M, Merkenschlager J, Gautam R, Oliveira T, et al. Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature. 2019;: pubmed publisher
Ohashi K, Wang Z, Yang Y, Billet S, Tu W, Pimienta M, et al. NOD-like receptor C4 Inflammasome Regulates the Growth of Colon Cancer Liver Metastasis in NAFLD. Hepatology. 2019;70:1582-1599 pubmed publisher
Rao Z, Zhang N, Xu N, Pan Y, Xiao M, Wu J, et al. 1,25-Dihydroxyvitamin D Inhibits LPS-Induced High-Mobility Group Box 1 (HMGB1) Secretion via Targeting the NF-E2-Related Factor 2-Hemeoxygenase-1-HMGB1 Pathway in Macrophages. Front Immunol. 2017;8:1308 pubmed publisher
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product information

Product Type :

Antibody

Product Name :

F4/80 Monoclonal Antibody (BM8), Super Bright 645, eBioscience

Catalog # :

64-4801-80

Quantity :

25 µg

Price :

US 159

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 1.0 µg/test

Species :

Mouse

Clone :

BM8

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

F4/80 antigen is a 160 kDa cell surface glycoprotein that is a member of the EGF TM7 family of proteins and shares 68% overall amino acid identity with human EGF module containing mucin like hormone receptor 1 (EMR1). Expression of F4/80 is heterogeneous and is reported to vary during macrophage maturation and activation. The F4/80 antigen is expressed on a wide range of mature tissue macrophages including Kupffer cells, Langerhans, microglia, macrophages located in the gut lamina propria, peritoneal cavity, lung, thymus, bone marrow stroma and macrophages in the red pulp of the spleen. F4/80 expression has also been reported on a subpopulation of dendritic cells but is absent from macrophages located in T cell areas of the spleen and lymph node. The ligands and biological functions of the F4/80 antigen have not yet been determined but recent studies suggest a role for F4/80 in the generation of efferent CD8+ve regulatory T cells.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1.0 µg/test

Aliases :

ADGRE1; Adhesion G protein-coupled receptor E1; Adhesion G protein-coupled receptor E2; cell surface glycoprotein EMR1; cell surface glycoprotein F4/80; DD7A5-7; EGF-like module containing, mucin-like, hormone receptor-like 1; EGF-like module containing, mucin-like, hormone receptor-like sequence 1; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EGF-TM7; Emr1; EMR1 hormone receptor; F4/80; Gpf480; Ly71; lymphocyte antigen 71; TM7LN3