This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD45R (B220) Monoclonal Antibody (RA3-6B2), Super Bright 645, eBioscience
catalog :
64-0452-82
quantity :
100 ug
price :
US 391.00
clonality :
monoclonal
host :
rat
conjugate :
Super Bright 645
clone name :
RA3-6B2
The same clone is also sold as:
The same clone is also sold as:
- Rockland Immunochemicals: 200-502-N84, 200-508-N84, 200-526-N84
- Exbio: 12-715-C100, 11-715-C025, 1A-715-C100, 1F-715-C025, 11-715-C100, 1A-715-C025, 1F-715-C100, 1P-715-C100, 1P-715-C025
- Bio-Rad: MCA1258SBUV605, MCA1258SBR815, MCA1258SBV570, MCA1258SBY605, MCA1258SBY720, MCA1258SBV670, MCA1258SBY575, MCA1258SBV475, MCA1258SBV760, MCA1258SBB810, MCA1258A647, MCA1258SBV610, MCA1258SBV440, MCA1258SBB675, MCA1258SBUV795, MCA1258SBV710, MCA1258SBUV400, MCA1258SBB615, MCA1258SBY800, MCA1258SBR715, MCA1258SBUV445, MCA1258SBY665, MCA1258SBR775, MCA1258SBUV510, MCA1258SBUV665, MCA1258SBB580, MCA1258SBB765, MCA1258GT, MCA1258G, MCA1258F, MCA1258SBR670, MCA1258SBB700, MCA1258SBV790, MCA1258SBUV740, MCA1258SBV515, MCA1258SBUV575
- Santa Cruz Biotechnology: sc-19597 L, sc-19597
- R&D Systems: FAB1217V-100, FAB1217F, MAB1217, FAB1217MFV450-100, FAB1217T-100UG, BAM1217, FAB1217G, FAB1217S-100UG, FAB1217N-025, FAB1217R-100UG, FAB1217P
- OriGene: SM034PT, SM034LE, SM034F, SM034P, SM034A, TA320453, SM034R
- ichorbio: ICH1130UL, ICH1130
- BioLegend: 103258, 103241, 103273, 103243, 103294, 103281, 103246, 103275, 103210, 103222, 103208, 103205, 103285, 103292, 103259, 103233, 103296, 103228, 103283, 103297, 103298, 103255, 103211, 103231, 103251, 103214, 103284, 103223, 103207, 103248, 103201, 103227, 103230, 103279, 103280, 103289, 103236, 103234, 103206, 103261, 103249, 103276, 103266, 103221, 103229, 103209, 103240, 103244, 103282, 103204, 103271, 103257, 103226, 103260, 103286, 103269, 103247, 103290, 103237, 103239, 103278, 103265, 103277, 103293, 103291, 103212, 103254, 103213, 103224, 103232, 103295, 103203, 103245, 103267, 103225, 103270, 103235, 103268, 103202, 103263, 103287
- Tonbo Biosciences: 30-0452, 70-0452, 65-0452
- BD Biosciences: 561226, 553093, 553084, 553085, 553086, 561086, 553092, 563103, 562922, 550286, 561877, 552094, 557957, 563894, 557683, 553088, 557390, 553083, 557669, 561880, 561878, 553091, 561879, 561101, 553087, 561102, 553090, 563793, 560473, 561227, 562290, 558108, 562313, 563708, 553089, 552771, 560472, 552772, 561881
- Abcam: ab210342
reactivity :
human, mouse
application :
flow cytometry
citations: 75
Reference |
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Mart xed n Hern xe1 ndez D, Guti xe9 rrez I, Gonz xe1 lez Prieto M, Macdowell K, Robledo Monta xf1 a J, Tendilla Beltr xe1 n H, et al. Sphk2 deletion is involved in structural abnormalities and Th17 response but does not aggravate colon inflammation induced by sub-chronic stress. Sci Rep. 2022;12:4073 pubmed publisher
|
Heimesaat M, Mousavi S, Kl xf8 ve S, Genger C, Weschka D, Tamas A, et al. Pituitary Adenylate Cyclase-Activating Polypeptide Alleviates Intestinal, Extra-Intestinal and Systemic Inflammatory Responses during Acute Campylobacter jejuni-induced Enterocolitis in Mice. Pathogens. 2020;9: pubmed publisher
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Cecchinato V, Bernasconi E, Speck R, Proietti M, Sauermann U, D Agostino G, et al. Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization. J Immunol. 2017;198:184-195 pubmed
|
Seehus C, Kaye J. In vitro Differentiation of Murine Innate Lymphoid Cells from Common Lymphoid Progenitor Cells. Bio Protoc. 2016;6: pubmed
|
product information
Product Type :
Antibody
Product Name :
CD45R (B220) Monoclonal Antibody (RA3-6B2), Super Bright 645, eBioscience
Catalog # :
64-0452-82
Quantity :
100 ug
Price :
US 391.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Human, Mouse
Applications :
Flow Cytometry: 0.5 ug/test
Species :
Human, Mouse
Clone :
RA3-6B2
Isotype :
IgG2a, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
CD45R (PTPRC) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. CD45 contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. CD45 is specifically expressed in hematopoietic cells and has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists in multiple isoforms as a result of alternative splicing, and these isoforms differ in their extracellular domains, but share identical transmembrane and cytoplasmic domains. Further, these CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. In addition to its role in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells. Diseases associated with CD45 dysfunction include Severe Combined Immunodeficiency (T-cell negative, B-Cell Negative) and Hepatitis C.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 ug/test
Aliases :
B220; Cd45; CD45 antigen; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LY5; Ly-5; Lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com81 Wyman Street
Waltham, MA USA 02451
800-678-5599
headquarters: USA
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