This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Ly-6A/E (Sca-1) Monoclonal Antibody (D7), Super Bright 600, eBioscience
catalog :
63-5981-82
quantity :
100 ug
price :
US 390.00
clonality :
monoclonal
host :
rat
conjugate :
Super Bright 600
reactivity :
mouse
application :
flow cytometry
citations: 46
Reference
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Griffin K, Thorpe S, Sebastian A, Hum N, Coonan T, Sagheb I, et al. Engineered bone marrow as a clinically relevant ex vivo model for primary bone cancer research and drug screening. Proc Natl Acad Sci U S A. 2023;120:e2302101120 pubmed publisher
Li N, Wang Y, Wang A, Zhang J, Jia C, Yu C, et al. STS1 and STS2 Phosphatase Inhibitor Baicalein Enhances the Expansion of Hematopoietic and Progenitor Stem Cells and Alleviates 5-Fluorouracil-Induced Myelosuppression. Int J Mol Sci. 2023;24: pubmed publisher
Ramadan R, Wouters V, van Neerven S, de Groot N, Garcia T, Muncan V, et al. The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut. Biol Open. 2022;11: pubmed publisher
Vasquez E, Nasreddin N, Valbuena G, Mulholland E, Belnoue Davis H, Eggington H, et al. Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia. Cell Stem Cell. 2022;29:1213-1228.e8 pubmed publisher
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Hamid T, Xu Y, Ismahil M, Rokosh G, Jinno M, Zhou G, et al. Cardiac Mesenchymal Stem Cells Promote Fibrosis and Remodeling in Heart Failure: Role of PDGF Signaling. JACC Basic Transl Sci. 2022;7:465-483 pubmed publisher
Soukup A, Matson D, Liu P, Johnson K, Bresnick E. Conditionally pathogenic genetic variants of a hematopoietic disease-suppressing enhancer. Sci Adv. 2021;7:eabk3521 pubmed publisher
Roy A, Tomaz da Silva M, Bhat R, Bohnert K, Iwawaki T, Kumar A. The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism. elife. 2021;10: pubmed publisher
Ahamad N, Sun Y, Nascimento Da Conceicao V, Xavier Paul Ezhilan C, Natarajan M, Singh B. Differential activation of Ca2+ influx channels modulate stem cell potency, their proliferation/viability and tissue regeneration. NPJ Regen Med. 2021;6:67 pubmed publisher
Kretzschmar K, Boonekamp K, Bleijs M, Asra P, Koomen M, Chuva de Sousa Lopes S, et al. Troy/Tnfrsf19 marks epidermal cells that govern interfollicular epidermal renewal and cornification. Stem Cell Reports. 2021;16:2379-2394 pubmed publisher
Hu Y, Li X, Zhi X, Cong W, Huang B, Chen H, et al. RANKL from bone marrow adipose lineage cells promotes osteoclast formation and bone loss. EMBO Rep. 2021;22:e52481 pubmed publisher
Wei Q, Pinho S, Dong S, Pierce H, Li H, Nakahara F, et al. MAEA is an E3 ubiquitin ligase promoting autophagy and maintenance of haematopoietic stem cells. Nat Commun. 2021;12:2522 pubmed publisher
Xu W, Ni C, Wang Y, Zheng G, Zhang J, Xu Y. Age-related trabecular bone loss is associated with a decline in serum Galectin-1 level. BMC Musculoskelet Disord. 2021;22:394 pubmed publisher
Proietti D, Giordani L, De Bardi M, D Ercole C, Lozanoska Ochser B, Amadio S, et al. Activation of skeletal muscle-resident glial cells upon nerve injury. JCI Insight. 2021;6: pubmed publisher
Sávio Silva C, Soinski Sousa P, Simplício Filho A, Bastos R, Beyerstedt S, Rangel E. Therapeutic Potential of Mesenchymal Stem Cells in a Pre-Clinical Model of Diabetic Kidney Disease and Obesity. Int J Mol Sci. 2021;22: pubmed publisher
Montecino Rodriguez E, Dorshkind K. Use of Busulfan to Condition Mice for Bone Marrow Transplantation. STAR Protoc. 2020;1:100159 pubmed publisher
Gao X, Zhang D, Xu C, Li H, Caron K, Frenette P. Nociceptive nerves regulate haematopoietic stem cell mobilization. Nature. 2021;589:591-596 pubmed publisher
Liu J, Qiu X, Lv Y, Zheng C, Dong Y, Dou G, et al. Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages. Stem Cell Res Ther. 2020;11:507 pubmed publisher
Jiang Y, Xu Z, Ma N, Yin L, Hao C, Li J. Effects of signaling pathway inhibitors on hematopoietic stem cells. Mol Med Rep. 2021;23: pubmed publisher
Deng C, Hu C, Ling S, Zhao N, Bao L, Zhou F, et al. Photoreceptor protection by mesenchymal stem cell transplantation identifies exosomal MiR-21 as a therapeutic for retinal degeneration. Cell Death Differ. 2021;28:1041-1061 pubmed publisher
Geng A, Wu T, Cai C, Song W, Wang J, Yu Q, et al. A novel function of R-spondin1 in regulating estrogen receptor expression independent of Wnt/β-catenin signaling. elife. 2020;9: pubmed publisher
Velletri T, Huang Y, Wang Y, Li Q, Hu M, Xie N, et al. Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerin. Cell Death Differ. 2021;28:156-169 pubmed publisher
Wilkes M, Siva K, Chen J, Varetti G, Youn M, Chae H, et al. Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase. Nat Commun. 2020;11:3344 pubmed publisher
Jiang M, Ye J, Wang X, Li N, Wang Y, Shi Y. Phosphatase SHP1 impedes mesenchymal stromal cell immunosuppressive capacity modulated by JAK1/STAT3 and P38 signals. Cell Biosci. 2020;10:65 pubmed publisher
Kroeger C, Roesler R, Wiese S, Hainzl A, Gatzka M. Interaction of Deubiquitinase 2A-DUB/MYSM1 with DNA Repair and Replication Factors. Int J Mol Sci. 2020;21: pubmed publisher
Zheng Y, Wang N, Wang S, Yang B, Situ H, Zhong L, et al. XIAOPI formula inhibits the pre-metastatic niche formation in breast cancer via suppressing TAMs/CXCL1 signaling. Cell Commun Signal. 2020;18:48 pubmed publisher
Houri K, Mori T, Onodera Y, Tsujimoto T, Takehara T, Nakao S, et al. miR-142 induces accumulation of reactive oxygen species (ROS) by inhibiting pexophagy in aged bone marrow mesenchymal stem cells. Sci Rep. 2020;10:3735 pubmed publisher
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product information
Product Type :
Antibody
Product Name :
Ly-6A/E (Sca-1) Monoclonal Antibody (D7), Super Bright 600, eBioscience
Catalog # :
63-5981-82
Quantity :
100 ug
Price :
US 390.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.25 ug/test
Species :
Mouse
Clone :
D7
Isotype :
IgG2a, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
Stem Cell Antigen-1 (Sca-1) is a member of the lymphocyte antigen 6 (Ly-6) family. It is expressed on multipotent hematopoietic stem cells (HSC) and is used as a marker of HSC in mice. Sca-1 is used in combination with lineage depletion antibodies to identify murine HSC. Sca-1 can be found in fetal liver, adult bone marrow, and adult peripheral blood and spleen. Sca-1 may be involved in the regulation of B and T cell activation.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.25 ug/test
Aliases :
9804; locus A/E; Locus AE; Ly6; Ly67; Ly6a; Ly-6A.2; Ly-6A.2/Ly-6E.1; Ly6A/E; Ly-6A/E; ly6a-e; Ly6e; Ly-6E; Ly-6E.1; lymphocyte antigen 6 complex; lymphocyte antigen 6 complex, locus A; lymphocyte antigen 6 complex, locus E; lymphocyte antigen 6A-2/6E-1; Lymphocyte antigen 6E; RIG-E; Sca1; Sca-1; Sca-2; stem cell antigen 1; Stem cell antigen 2; TAP; T-cell-activating protein; thymic shared antigen 1; Tsa1; TSA-1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA