CD171 Monoclonal Antibody (eBio5G3 (5G3)), Super Bright 600, eBioscience | Invitrogen 63-1719-41 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD171 Monoclonal Antibody (eBio5G3 (5G3)), Super Bright 600, eBioscience

catalog :

63-1719-41

quantity :

25 Tests

price :

US 201.00

clonality :

monoclonal

host :

mouse

conjugate :

Super Bright 600

clone name :

eBio5G3 (5G3)

reactivity :

human

application :

flow cytometry

citations: 7

Reference
You Y, Zhang Z, Sultana N, Ericsson M, Martens Y, Sun M, et al. ATP1A3 as a target for isolating neuron-specific extracellular vesicles from human brain and biofluids. Sci Adv. 2023;9:eadi3647 pubmed publisher
Winston C, Sukreet S, Lynch H, Lee V, Wilcock D, Nelson P, et al. Evaluation of blood-based, extracellular vesicles as biomarkers for aging-related TDP-43 pathology. Alzheimers Dement (Amst). 2022;14:e12365 pubmed publisher
Burrows K, Figueroa Hall L, Kuplicki R, Stewart J, Alarbi A, Ramesh R, et al. Neuronally-enriched exosomal microRNA-27b mediates acute effects of ibuprofen on reward-related brain activity in healthy adults: a randomized, placebo-controlled, double-blind trial. Sci Rep. 2022;12:861 pubmed publisher
Delgado Peraza F, Nogueras Ortiz C, Volpert O, Liu D, Goetzl E, Mattson M, et al. Neuronal and Astrocytic Extracellular Vesicle Biomarkers in Blood Reflect Brain Pathology in Mouse Models of Alzheimer's Disease. Cells. 2021;10: pubmed publisher
Lee E, Winston Gray C, Barlow J, Rissman R, Jeste D. Plasma Levels of Neuron- and Astrocyte-Derived Exosomal Amyloid Beta1-42, Amyloid Beta1-40, and Phosphorylated Tau Levels in Schizophrenia Patients and Non-psychiatric Comparison Subjects: Relationships With Cognitive Functioning and Psychopathology. Front Psychiatry. 2020;11:532624 pubmed publisher
Nasca C, Dobbin J, Bigio B, Watson K, De Angelis P, Kautz M, et al. Insulin receptor substrate in brain-enriched exosomes in subjects with major depression: on the path of creation of biosignatures of central insulin resistance. Mol Psychiatry. 2021;26:5140-5149 pubmed publisher
Er E, Valiente M, Ganesh K, Zou Y, Agrawal S, Hu J, et al. Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization. Nat Cell Biol. 2018;20:966-978 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD171 Monoclonal Antibody (eBio5G3 (5G3)), Super Bright 600, eBioscience

Catalog # :

63-1719-41

Quantity :

25 Tests

Price :

US 201.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (0.25 ug)/test

Species :

Human

Clone :

eBio5G3 (5G3)

Isotype :

IgG2a

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

L1CAM/CD171 is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.25 ug)/test

Aliases :

antigen identified by monoclonal antibody R1; CAML1; CD 171; CD171; CD171 molecule; HSAS; HSAS1; Hyd; L1; L1 cell adhesion molecule; L1CAM; MASA; MIC5; N-CAM L1; NCAML1; N-CAML1; N-CAM-L1; NCAM-L1; Nerve-growth factor-inducible large external glycoprotein; neural cell adhesion molecule L1; NILE; S10; sCD171; sL1 CAM; sL1CAM; soluble CD 171; soluble CD171; soluble L1 CAM; soluble L1CAM; SPG1