This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
TLR4/MD-2 Complex Monoclonal Antibody (MTS510), Super Bright 436, eBioscience
catalog :
62-9924-82
quantity :
100 ug
price :
US 449.00
clonality :
monoclonal
host :
rat
conjugate :
Super Bright 436
clone name :
MTS510

The same clone is also sold as:
reactivity :
mouse
application :
flow cytometry
citations: 4
Reference
Hu J, Wang X, Chen X, Fang Y, Chen K, Peng W, et al. Hydroxychloroquine attenuates neuroinflammation following traumatic brain injury by regulating the TLR4/NF-κB signaling pathway. J Neuroinflammation. 2022;19:71 pubmed publisher
Choi J, Lim J, Kim H. Lycopene Inhibits Toll-Like Receptor 4-Mediated Expression of Inflammatory Cytokines in House Dust Mite-Stimulated Respiratory Epithelial Cells. Molecules. 2021;26: pubmed publisher
Quirino Teixeira A, Rozini S, Barbosa Lima G, Coelho D, Carneiro P, Mohana Borges R, et al. Inflammatory signaling in dengue-infected platelets requires translation and secretion of nonstructural protein 1. Blood Adv. 2020;4:2018-2031 pubmed publisher
Kumazoe M, Nakamura Y, Yamashita M, Suzuki T, Takamatsu K, Huang Y, et al. Green Tea Polyphenol Epigallocatechin-3-gallate Suppresses Toll-like Receptor 4 Expression via Up-regulation of E3 Ubiquitin-protein Ligase RNF216. J Biol Chem. 2017;292:4077-4088 pubmed publisher
product information
Product Type :
Antibody
Product Name :
TLR4/MD-2 Complex Monoclonal Antibody (MTS510), Super Bright 436, eBioscience
Catalog # :
62-9924-82
Quantity :
100 ug
Price :
US 449.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.5 ug/test
Species :
Mouse
Clone :
MTS510
Isotype :
IgG2a, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2; e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 ug/test
Aliases :
ARMD10; CD284; Esop1; ESOP-1; hToll; lipopolysaccharide response; Lps; Ly87; Ly96; Ly-96; Lymphocyte antigen 96; Md2; MD-2; myeloid differentiation factor-2; myeloid differentiation protein-2; protein MD-2; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; Toll-like receptor 4
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA