CD133 (Prominin-1) Monoclonal Antibody (TMP4), Super Bright 436, eBioscience | Invitrogen 62-1338-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD133 (Prominin-1) Monoclonal Antibody (TMP4), Super Bright 436, eBioscience

catalog :

62-1338-42

quantity :

100 Tests

price :

US 407.00

clonality :

monoclonal

host :

mouse

conjugate :

Super Bright 436

clone name :

TMP4

reactivity :

human

application :

flow cytometry

citations: 5

Reference
Voit R, Tao L, Yu F, Cato L, Cohen B, Fleming T, et al. A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia. Nat Immunol. 2023;24:69-83 pubmed publisher
Mo L, Su B, Xu L, Hu Z, Li H, Du H, et al. MCM7 supports the stemness of bladder cancer stem-like cells by enhancing autophagic flux. iScience. 2022;25:105029 pubmed publisher
Pasquale V, Ducci G, Campioni G, Ventrici A, Assalini C, Busti S, et al. Profiling and Targeting of Energy and Redox Metabolism in Grade 2 Bladder Cancer Cells with Different Invasiveness Properties. Cells. 2020;9: pubmed publisher
Jia J, Yu F, Xiong Y, Wei W, Ma H, Nisi F, et al. Chemerin enhances the adhesion and migration of human endothelial progenitor cells and increases lipid accumulation in mice with atherosclerosis. Lipids Health Dis. 2020;19:207 pubmed publisher
Li F, Hu Q, He T, Xu J, Yi Y, Xie S, et al. The Deubiquitinase USP4 Stabilizes Twist1 Protein to Promote Lung Cancer Cell Stemness. Cancers (Basel). 2020;12: pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD133 (Prominin-1) Monoclonal Antibody (TMP4), Super Bright 436, eBioscience

Catalog # :

62-1338-42

Quantity :

100 Tests

Price :

US 407.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (0.25 ug)/test

Species :

Human

Clone :

TMP4

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

The CD133 (AC133) antigen is a 97 kDa glycoprotein, with 5 transmembrane domains, that shows up as a 120 kDa band on protein gels due to glycosylation. CD133 is a cell surface marker expressed by immature hematopoietic stem cells but not mature blood cells. In addition to hematopoietic stem and progenitor cells, CD133 has been found to be a marker for other stem and progenitor cells including neural and embryonic stem cells. CD133 has been shown to be expressed in cancers, including some leukemias and brain tumors, that may be derived from stem cells. Low level expression could also be detected in the kidney, pancreas, placenta, and fetal liver. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of the CD133 gene is also associated with several types of cancer. CD133 is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner, and multiple transcript variants encoding different isoforms have been found.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.25 ug)/test

Aliases :

4932416E19Rik; AC133; Antigen AC133; antigen AC133 homolog; antigen CD133; CD107b; CD133; CORD12; fudenine; hematopoietic stem cell antigen; hProminin; Lamp II; Lamp2; LAMP-2; Lamp-2a; Lamp-2b; Lamp-2c; LGP-96; LGP-B; Mac3; MCDR2; MSTP061; Prom; PROM1; Prom-1; prominin 1; prominin 1.s1; Prominin1; prominin-1; prominin-1.s2; prominin-like 1; prominin-like protein 1; PROML1; RP41; STGD4