CD123 Monoclonal Antibody (6H6), Super Bright 436, eBioscience | Invitrogen 62-1239-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD123 Monoclonal Antibody (6H6), Super Bright 436, eBioscience

catalog :

62-1239-42

quantity :

100 Tests

price :

US 372.00

clonality :

monoclonal

host :

mouse

conjugate :

Super Bright 436

clone name :

6H6

The same clone is also sold as:

Santa Cruz Biotechnology: sc-80650
BioLegend: 306040, 306044, 306009, 306051, 306050, 306015, 306013, 306041, 306010, 306024, 306035, 306053, 306021, 983712, 306031, 306016, 306056, 306054, 983704, 983706, 306037, 306002, 306025, 306019, 306022, 983708, 306026, 306004, 306047, 306011, 306034, 306055, 306012, 306023, 306036, 306032, 306042, 306017, 983702, 306008, 306033, 306027, 306018, 306049, 306005, 306045, 306029, 306043, 306014, 306006, 306030, 306020, 260016, 306039, 285054, 983710
Abcam: ab21562, ab21560, ab157332
OriGene: SM1190BT, SM1190P, SM1190AC
Novus Biologicals: NB600-1185
Exbio: 1B-700-C025, T9-700-T100, T9-700-T025, 1B-700-C100, 1A-700-T025, 1A-700-T100, T8-700-T025, T8-700-T100, T7-700-T100, 11-700-C025, 1F-700-T100, 11-700-C100, 1P-700-T100, 1P-700-T025, T7-700-T025, 1F-700-T025
Bio-Rad: MCA1263PE

reactivity :

human

application :

flow cytometry

citations: 11

Reference
Im K, Huppert L, Malevanchik L, Rugo H, Combes A, Campbell M, et al. High-dimensional immune cell profiling of cerebrospinal fluid from patients with metastatic breast cancer and leptomeningeal disease. NPJ Breast Cancer. 2023;9:22 pubmed publisher
Ogishi M, Arias A, Yang R, Han J, Zhang P, Rinchai D, et al. Impaired IL-23-dependent induction of IFN-γ underlies mycobacterial disease in patients with inherited TYK2 deficiency. J Exp Med. 2022;219: pubmed publisher
Baumgaertner P, Sankar M, Herrera F, Benedetti F, Barras D, Thierry A, et al. Unsupervised Analysis of Flow Cytometry Data in a Clinical Setting Captures Cell Diversity and Allows Population Discovery. Front Immunol. 2021;12:633910 pubmed publisher
Yu C, Littleton S, Giroux N, Mathew R, Ding S, Kalnitsky J, et al. Mucosal-associated invariant T cell responses differ by sex in COVID-19. Med (N Y). 2021;2:755-772.e5 pubmed publisher
Ben Othman R, Cai B, Liu A, Varankovich N, He D, Blimkie T, et al. Systems Biology Methods Applied to Blood and Tissue for a Comprehensive Analysis of Immune Response to Hepatitis B Vaccine in Adults. Front Immunol. 2020;11:580373 pubmed publisher
Psaila B, Wang G, Rodriguez Meira A, Li R, Heuston E, Murphy L, et al. Single-Cell Analyses Reveal Megakaryocyte-Biased Hematopoiesis in Myelofibrosis and Identify Mutant Clone-Specific Targets. Mol Cell. 2020;78:477-492.e8 pubmed publisher
Bastian O, Croes M, Alblas J, Koenderman L, Leenen L, Blokhuis T. Neutrophils Inhibit Synthesis of Mineralized Extracellular Matrix by Human Bone Marrow-Derived Stromal Cells In Vitro. Front Immunol. 2018;9:945 pubmed publisher
Raap U, Gehring M, Kleiner S, Rüdrich U, Eiz Vesper B, Haas H, et al. Human basophils are a source of - and are differentially activated by - IL-31. Clin Exp Allergy. 2017;47:499-508 pubmed publisher
Ataide M, Andrade W, Zamboni D, Wang D, Souza M, Franklin B, et al. Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection. PLoS Pathog. 2014;10:e1003885 pubmed publisher
Compte N, Zouaoui Boudjeltia K, Vanhaeverbeek M, De Breucker S, Tassignon J, Trelcat A, et al. Frailty in old age is associated with decreased interleukin-12/23 production in response to toll-like receptor ligation. PLoS ONE. 2013;8:e65325 pubmed publisher
Meera S, Madhuri T, Manisha G, Ramesh P. Irreversible loss of pDCs by apoptosis during early HIV infection may be a critical determinant of immune dysfunction. Viral Immunol. 2010;23:241-9 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD123 Monoclonal Antibody (6H6), Super Bright 436, eBioscience

Catalog # :

62-1239-42

Quantity :

100 Tests

Price :

US 372.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (0.25 ug)/Test

Species :

Human

Clone :

6H6

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

IL-3Ra (Interleukin-3 receptor subunit alpha) belongs to the type I cytokine receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CDw131) subunit. IL-3Ra is responsible for the transmission of signal of Interleukin-3. IL-3Ra and IL-3Rb chain heterodimerization is induced by Interleukin-3, which is required for receptor activation but not high affinity binding. IL-3Ra is also reported that IL-3Ra subunits are overexpressed on acute myeloid leukemia (AML) blasts compared with normal hematopoietic cells and are thus potential targets for novel therapeutic agents.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.25 ug)/Test

Aliases :

CD123; CD123 antigen; CDw123; Cyrl; cytokine receptor-like protein CYRL; hIL-3Ra; Il-3 alpha subunit; IL-3 receptor alpha chain; IL-3 receptor alpha SP2 isoform; IL-3 receptor subunit alpha; IL3R; IL-3R subunit alpha; Il3ra; IL-3RA; IL-3R-alpha; IL3RAY; IL3RX; IL3RY; interleukin 3 receptor subunit alpha; interleukin 3 receptor, alpha; interleukin 3 receptor, alpha (low affinity); interleukin 3 receptor, alpha chain; interleukin-3 receptor class II alpha chain; Interleukin-3 receptor subunit alpha; Sut-1