This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD69 Monoclonal Antibody (H1.2F3), Super Bright 436, eBioscience
catalog :
62-0691-82
quantity :
100 ug
price :
US 366.00
clonality :
monoclonal
host :
hamsters
conjugate :
Super Bright 436
clone name :
H1.2F3

The same clone is also sold as:
reactivity :
mouse
application :
flow cytometry
citations: 30
Reference
Chapoval S, Gao H, Fanaroff R, Keegan A. Plexin B1 controls Treg numbers, limits allergic airway inflammation, and regulates mucins. Front Immunol. 2023;14:1297354 pubmed publisher
Jiang Y, Zhao J, Wang M, Huang F, Li J, Liu R, et al. Mesenchymal stem cell-derived exosomes can alleviate GVHD and preserve the GVL effect in allogeneic stem cell transplantation animal models. Front Immunol. 2023;14:1284936 pubmed publisher
Xie T, Liu X, Li P. CD138 promotes the accumulation and activation of autoreactive T cells in autoimmune MRL/lpr mice. Exp Ther Med. 2023;26:568 pubmed publisher
Yu L, Zhou B, Zhu Y, Li L, Zhong Y, Zhu L, et al. HSF1 promotes CD69+ Treg differentiation to inhibit colitis progression. Theranostics. 2023;13:1892-1905 pubmed publisher
Akasaka D, Iguchi S, Kaneko R, Yoshiga Y, Kajiwara D, Nakachi Y, et al. Novel Bruton's tyrosine kinase inhibitor TAS5315 suppresses the progression of inflammation and joint destruction in rodent collagen-induced arthritis. PLoS ONE. 2023;18:e0282117 pubmed publisher
Kovacs M, Cowan M, Babcock I, Sibley L, Still K, Batista S, et al. Meningeal lymphatic drainage promotes T cell responses against Toxoplasma gondii but is dispensable for parasite control in the brain. elife. 2022;11: pubmed publisher
Li J, Huang F, Jiang Y, Zhao J, Wan J, Hao S. A novel costimulatory molecule gene-modified leukemia cell-derived exosome-targeted CD4+ T cell vaccine efficiently enhances anti-leukemia immunity. Front Immunol. 2022;13:1043484 pubmed publisher
Li N, Wu J, Qi M, Wang Z, Zhang S, Li X, et al. CP-25 exerts a protective effect against ConA-induced hepatitis via regulating inflammation and immune response. Front Pharmacol. 2022;13:1041671 pubmed publisher
Jiang W, Wang X, Su Y, Cai L, Li J, Liang J, et al. Intranasal Immunization With a c-di-GMP-Adjuvanted Acellular Pertussis Vaccine Provides Superior Immunity Against Bordetella pertussis in a Mouse Model. Front Immunol. 2022;13:878832 pubmed publisher
Basu J, Zha J, Nicolas E, Coulton M, Czyzewicz P, Hua X, et al. An autonomous TCR signal-sensing switch influences CD4/CD8 lineage choice in mice. Commun Biol. 2022;5:84 pubmed publisher
Yu H, Yang W, Huang J, Miao X, Wang B, Ren X, et al. GPR120 induces regulatory dendritic cells by inhibiting HK2-dependent glycolysis to alleviate fulminant hepatic failure. Cell Death Dis. 2021;13:1 pubmed publisher
Han Q, Mu Y, Zhao H, Zhao R, Guo Q, Su Y, et al. Fasudil prevents liver fibrosis via activating natural killer cells and suppressing hepatic stellate cells. World J Gastroenterol. 2021;27:3581-3594 pubmed publisher
Sangaletti S, Botti L, Gulino A, Lecis D, Bassani B, Portararo P, et al. SPARC regulation of PMN clearance protects from pristane-induced lupus and rheumatoid arthritis. iScience. 2021;24:102510 pubmed publisher
Sasai M, Ma J, Okamoto M, Nishino K, Nagaoka H, Takashima E, et al. Uncovering a novel role of PLCβ4 in selectively mediating TCR signaling in CD8+ but not CD4+ T cells. J Exp Med. 2021;218: pubmed publisher
Lin P, Liang C, Yao B, Chen H, Pan C, Wu L, et al. Robust induction of TRMs by combinatorial nanoshells confers cross-strain sterilizing immunity against lethal influenza viruses. Mol Ther Methods Clin Dev. 2021;21:299-314 pubmed publisher
Kim H, Park J, Park J, Yasmin F, Kim C, Oh S, et al. Cell-permeable transgelin-2 as a potent therapeutic for dendritic cell-based cancer immunotherapy. J Hematol Oncol. 2021;14:43 pubmed publisher
Kim H, Park J, Fatima Y, Kausar M, Park J, Jun C. Potentiating the Antitumor Activity of Cytotoxic T Cells via the Transmembrane Domain of IGSF4 That Increases TCR Avidity. Front Immunol. 2020;11:591054 pubmed publisher
Vonderhaar E, Barnekow N, McAllister D, McOlash L, Eid M, Riese M, et al. STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer. Cell Mol Gastroenterol Hepatol. 2021;12:41-58 pubmed publisher
Dubois V, Chatagnon J, Thiriard A, Bauderlique Le Roy H, Debrie A, Coutte L, et al. Suppression of mucosal Th17 memory responses by acellular pertussis vaccines enhances nasal Bordetella pertussis carriage. NPJ Vaccines. 2021;6:6 pubmed publisher
Acharya T, Tiwari A, Majhi R, Goswami C. TRPM8 channel augments T-cell activation and proliferation. Cell Biol Int. 2021;45:198-210 pubmed publisher
Shao B, Wang L, Yu Y, Chen L, Gan N, Huang W. Effects of CD4+ T lymphocytes from ovariectomized mice on bone marrow mesenchymal stem cell proliferation and osteogenic differentiation. Exp Ther Med. 2020;20:84 pubmed publisher
Liu Y, Bockermann R, Hadi M, Safari I, Carrion B, Kveiborg M, et al. ADAM12 is a costimulatory molecule that determines Th1 cell fate and mediates tissue inflammation. Cell Mol Immunol. 2020;: pubmed publisher
Ho J, Angel M, Ma Y, Sloan E, Wang G, Martínez Romero C, et al. Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection. Cell. 2020;181:1502-1517.e23 pubmed publisher
Markman J, Porritt R, Wakita D, Lane M, Martinon D, Noval Rivas M, et al. Loss of testosterone impairs anti-tumor neutrophil function. Nat Commun. 2020;11:1613 pubmed publisher
Hajaj E, Eisenberg G, Klein S, Frankenburg S, Merims S, Ben David I, et al. SLAMF6​ deficiency augments tumor killing and skews toward an effector phenotype revealing it as a novel T cell checkpoint. elife. 2020;9: pubmed publisher
Wilgenburg B, Loh L, Chen Z, Pediongco T, Wang H, Shi M, et al. MAIT cells contribute to protection against lethal influenza infection in vivo. Nat Commun. 2018;9:4706 pubmed publisher
Si Y, Wen Y, Kelly S, Chong A, Collier J. Intranasal delivery of adjuvant-free peptide nanofibers elicits resident CD8+ T cell responses. J Control Release. 2018;282:120-130 pubmed publisher
Chu F, Hu Y, Zhou Y, Guo M, Lu J, Zheng W, et al. MicroRNA-126 deficiency enhanced the activation and function of CD4+ T cells by elevating IRS-1 pathway. Clin Exp Immunol. 2017;: pubmed publisher
Chi H, Hua K, Lin Y, Chu C, Hsieh C, Hsu Y, et al. IL-36 Signaling Facilitates Activation of the NLRP3 Inflammasome and IL-23/IL-17 Axis in Renal Inflammation and Fibrosis. J Am Soc Nephrol. 2017;28:2022-2037 pubmed publisher
Fernandez Orth J, Ehling P, Ruck T, Pankratz S, Hofmann M, Landgraf P, et al. 14-3-3 Proteins regulate K2P 5.1 surface expression on T lymphocytes. Traffic. 2017;18:29-43 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD69 Monoclonal Antibody (H1.2F3), Super Bright 436, eBioscience
Catalog # :
62-0691-82
Quantity :
100 ug
Price :
US 366.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Armenian Hamster
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.5 ug/test
Species :
Mouse
Clone :
H1.2F3
Isotype :
IgG
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
CD69 (AIM, Active Inducer Molecule) is a gp28/34 disulfide bonded homodimer with a molecular weight of 60 kDa under non-reducing conditions. CD69 contains one or two N linked oligosacaride and the molecule is present on activated platelets. In normal peripheral blood a variable percentage of cells express the CD69 antigen, and it is involved in lymphocyte signal transduction. Expression CD69 is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. Alternative splicing results in multiple transcript variants of CD69. Diseases associated with CD69 dysfunction include coccidiodomycosis and asthma.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 ug/test
Aliases :
5830438K24Rik; Activation inducer molecule; activation inducer molecule (AIM/CD69); AI452015; AIM; BL-AC/P26; CD69; CD69 antigen; CD69 antigen (p60, early T-cell activation antigen); CD69 molecule; CLEC2C; C-type lectin domain family 2 member C; C-type lectin domain family 2, member C; EA1; early activation antigen CD69; early lymphocyte activation antigen; early T-cell activation antigen p60; GP32/28; leukocyte surface antigen Leu-23; MLR-3; VEA; Very Early Activation Antigen
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA