This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD45RO Monoclonal Antibody (UCHL1), Super Bright 436, eBioscience
catalog :
62-0457-42
quantity :
100 Tests
price :
US 365.00
clonality :
monoclonal
host :
mouse
conjugate :
Super Bright 436
clone name :
UCHL1

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
citations: 6
Reference
Ye X, Shih D, Ku Z, Hong J, Barrett D, Rupp R, et al. Transcriptional signature of durable effector T cells elicited by a replication defective HCMV vaccine. NPJ Vaccines. 2024;9:70 pubmed publisher
Zhang Y, Luo F, Dong K. Soluble NKG2D ligands impair CD8+ T cell antitumor function dependent of NKG2D downregulation in neuroblastoma. Oncol Lett. 2023;26:297 pubmed publisher
Dhariwala M, Karthikeyan D, Vasquez K, Farhat S, Weckel A, Taravati K, et al. Developing Human Skin Contains Lymphocytes Demonstrating a Memory Signature. Cell Rep Med. 2020;1:100132 pubmed publisher
Gartner M, Gorry P, Tumpach C, Zhou J, Dantanarayana A, Chang J, et al. Longitudinal analysis of subtype C envelope tropism for memory CD4+ T cell subsets over the first 3 years of untreated HIV-1 infection. Retrovirology. 2020;17:24 pubmed publisher
de Macedo Abdo L, Barros L, Saldanha Viegas M, Vieira Codeço Marques L, de Sousa Ferreira P, Chicaybam L, et al. Development of CAR-T cell therapy for B-ALL using a point-of-care approach. Oncoimmunology. 2020;9:1752592 pubmed publisher
Sheng S, Gu Y, Lu C, Tang Y, Zou J, Zhang Y, et al. The Characteristics of Naive-like T Cells in Tumor-infiltrating Lymphocytes From Human Lung Cancer. J Immunother. 2017;40:1-10 pubmed
product information
Product Type :
Antibody
Product Name :
CD45RO Monoclonal Antibody (UCHL1), Super Bright 436, eBioscience
Catalog # :
62-0457-42
Quantity :
100 Tests
Price :
US 365.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 5 uL (1.0 ug)/test
Species :
Human
Clone :
UCHL1
Isotype :
IgG2a, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
CD45RO (UCHL1, ubiquitin carboxyl terminal esterase L1) is the shortest isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45RO is expressed on macrophages, CD8+ T cells, activated T cells and myeloma cells. Besides the role in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 uL (1.0 ug)/test
Aliases :
B220; Cd45; CD45 antigen; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; PTPRC; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA