CD41a Monoclonal Antibody (eBioMWReg30 (MWReg30)), Super Bright 436, eBioscience | Invitrogen 62-0411-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD41a Monoclonal Antibody (eBioMWReg30 (MWReg30)), Super Bright 436, eBioscience

catalog :

62-0411-82

quantity :

100 ug

price :

US 401.00

clonality :

monoclonal

host :

rat

conjugate :

Super Bright 436

clone name :

eBioMWReg30 (MWReg30)

reactivity :

mouse

application :

flow cytometry

citations: 8

Reference
Maytum A, Edginton White B, Keane P, Cockerill P, Cazier J, Bonifer C. Chromatin priming elements direct tissue-specific gene activity before hematopoietic specification. Life Sci Alliance. 2024;7: pubmed publisher
Jiang M, Wu W, Xia Y, Wang X, Liang J. Platelet-derived extracellular vesicles promote endothelial dysfunction in sepsis by enhancing neutrophil extracellular traps. BMC Immunol. 2023;24:22 pubmed publisher
Coulombe P, Cole G, Fentiman A, Parker J, Yung E, Bilenky M, et al. Meis1 establishes the pre-hemogenic endothelial state prior to Runx1 expression. Nat Commun. 2023;14:4537 pubmed publisher
Cardenas R, Gonzalez R, Sanchez E, Ramos M, Cardenas E, Rodarte A, et al. SNAP23 is essential for platelet and mast cell development and required in connective tissue mast cells for anaphylaxis. J Biol Chem. 2021;296:100268 pubmed publisher
Tang D, Liu S, Sun H, Qin X, Zhou N, Zheng W, et al. All-trans-retinoic acid shifts Th1 towards Th2 cell differentiation by targeting NFAT1 signalling to ameliorate immune-mediated aplastic anaemia. Br J Haematol. 2020;191:906-919 pubmed publisher
Bernitz J, Kim H, MacArthur B, SIEBURG H, Moore K. Hematopoietic Stem Cells Count and Remember Self-Renewal Divisions. Cell. 2016;167:1296-1309.e10 pubmed publisher
Chen I, Caprioli A, Ohnuki H, Kwak H, Porcher C, Tosato G. EphrinB2 regulates the emergence of a hemogenic endothelium from the aorta. Sci Rep. 2016;6:27195 pubmed publisher
Beaulieu L, Clancy L, Tanriverdi K, Benjamin E, Kramer C, Weinberg E, et al. Specific Inflammatory Stimuli Lead to Distinct Platelet Responses in Mice and Humans. PLoS ONE. 2015;10:e0131688 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD41a Monoclonal Antibody (eBioMWReg30 (MWReg30)), Super Bright 436, eBioscience

Catalog # :

62-0411-82

Quantity :

100 ug

Price :

US 401.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 1.0 ug/test

Species :

Mouse

Clone :

eBioMWReg30 (MWReg30)

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits -120 kDa a, alpha and 23 kDa b, beta- that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. CD41 is also involved in blood coagulation by mediating platelet aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during the early stages of hematopoietic differentiation. Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia, and Platelet type-16 bleeding disorder.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1.0 ug/test

Aliases :

AI172977; alpha IIb; alphaIIb; alphaIIb protein; BDPLT16; BDPLT2; CD41; CD41B; form 1; form 2; GP IIb; GP2B; GPalpha IIb; GPIIb; GT; GTA; HPA3; integrin alpha 2b; integrin alpha 2b (Cd41b); integrin alpha-IIb; Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2; integrin subunit alpha 2b; integrin subunit alpha IIb; integrin, alpha 2B; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); ITGA2B; ITGAB; platelet fibrinogen receptor, alpha subunit; platelet glycoprotein IIb; platelet glycoprotein IIb of IIb/II Ia complex; platelet glycoprotein IIb of IIb/IIIa complex; platelet membrane glycoprotein IIb; platelet-specific antigen BAK; PPP1R93; protein phosphatase 1, regulatory subunit 93