product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
ZO-1 Polyclonal Antibody
catalog :
61-7300
quantity :
100 µg
price :
425 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
guinea pig, human, mouse, rat, dogs, pigs , zebrafish , domestic rabbit
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
more info or order :
citations: 279
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; loading ...; fig s2b
Trevisan A, Bauer M, Brindley R, Currie K, Carter B. Jedi-1 deficiency increases sensory neuron excitability through a non-cell autonomous mechanism. Sci Rep. 2020;10:1300 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 1d
Marin Navarro A, Pronk R, van der Geest A, Oliynyk G, Nordgren A, Arsenian Henriksson M, et al. p53 controls genomic stability and temporal differentiation of human neural stem cells and affects neural organization in human brain organoids. Cell Death Dis. 2020;11:52 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:150; loading ...; fig 2a
Bertrand L, Méroth F, Tournebize M, Leda A, Sun E, Toborek M. Targeting the HIV-infected brain to improve ischemic stroke outcome. Nat Commun. 2019;10:2009 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 1c
Ferraro D, Patella F, Zanivan S, Donato C, Aceto N, Giannotta M, et al. Endothelial cell-derived nidogen-1 inhibits migration of SK-BR-3 breast cancer cells. BMC Cancer. 2019;19:312 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 2d
Kiyohara H, Sujino T, Teratani T, Miyamoto K, Arai M, Nomura E, et al. Toll-Like Receptor 7 Agonist-Induced Dermatitis Causes Severe Dextran Sulfate Sodium Colitis by Altering the Gut Microbiome and Immune Cells. Cell Mol Gastroenterol Hepatol. 2019;7:135-156 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig ev1b
Feldner A, Adam M, Tetzlaff F, Moll I, Komljenovic D, Sahm F, et al. Loss of Mpdz impairs ependymal cell integrity leading to perinatal-onset hydrocephalus in mice. EMBO Mol Med. 2017;9:890-905 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:300; loading ...; fig s4a
  • western blot; mouse; 1:1000; loading ...; fig 3b
Yanagida K, Liu C, Faraco G, Galvani S, Smith H, Burg N, et al. Size-selective opening of the blood-brain barrier by targeting endothelial sphingosine 1-phosphate receptor 1. Proc Natl Acad Sci U S A. 2017;114:4531-4536 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig 2b
Samuel W, Jaworski C, Postnikova O, Kutty R, Duncan T, Tan L, et al. Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells. Mol Vis. 2017;23:60-89 pubmed
  • immunocytochemistry; mouse; loading ...; fig 1a
Balmer D, Bapst Wicht L, Pyakurel A, Emery M, Nanchen N, Bochet C, et al. Bis-Retinoid A2E Induces an Increase of Basic Fibroblast Growth Factor via Inhibition of Extracellular Signal-Regulated Kinases 1/2 Pathway in Retinal Pigment Epithelium Cells and Facilitates Phagocytosis. Front Aging Neurosci. 2017;9:43 pubmed publisher
  • immunohistochemistry; human; 1:500; fig 2A
Geng Z, Walsh P, Truong V, Hill C, Ebeling M, Kapphahn R, et al. Generation of retinal pigmented epithelium from iPSCs derived from the conjunctiva of donors with and without age related macular degeneration. PLoS ONE. 2017;12:e0173575 pubmed publisher
  • western blot; mouse; loading ...; fig 4f
Tung K, Harakal J, Qiao H, Rival C, Li J, Paul A, et al. Egress of sperm autoantigen from seminiferous tubules maintains systemic tolerance. J Clin Invest. 2017;127:1046-1060 pubmed publisher
  • immunocytochemistry; mouse; 1:25; fig 8b
Zhang J, Chen S, Cai J, Hou Z, Wang X, Kachelmeier A, et al. Culture media-based selection of endothelial cells, pericytes, and perivascular-resident macrophage-like melanocytes from the young mouse vestibular system. Hear Res. 2017;345:10-22 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:200; loading ...; fig 5X'
Kozlovskaja GumbrienÄ— A, Yi R, Alexander R, Aman A, Jiskra R, Nagelberg D, et al. Proliferation-independent regulation of organ size by Fgf/Notch signaling. elife. 2017;6: pubmed publisher
  • immunocytochemistry; human; 1:300; loading ...; fig s2f
Priya R, Liang X, Teo J, Duszyc K, Yap A, Gomez G. ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens. Mol Biol Cell. 2017;28:12-20 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig 4b
  • western blot; human; 1:1000; loading ...; tbl 3
Sivagurunathan S, Palanisamy K, Arunachalam J, Chidambaram S. Possible role of HIWI2 in modulating tight junction proteins in retinal pigment epithelial cells through Akt signaling pathway. Mol Cell Biochem. 2017;427:145-156 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:250; fig 7a
  • western blot; rat; 1:1000; fig 7g
Cao X, Shen L, Wu S, Yan C, Zhou Y, Xiong G, et al. Urban fine particulate matter exposure causes male reproductive injury through destroying blood-testis barrier (BTB) integrity. Toxicol Lett. 2017;266:1-12 pubmed publisher
  • immunocytochemistry; domestic rabbit; 1:100; loading ...; fig 6a
Martínez Rendón J, Sánchez Guzmán E, Rueda A, González J, Gulias Cañizo R, Aquino Jarquin G, et al. TRPV4 Regulates Tight Junctions and Affects Differentiation in a Cell Culture Model of the Corneal Epithelium. J Cell Physiol. 2017;232:1794-1807 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 7b
Chehaibi K, le Maire L, Bradoni S, Escolà J, Blanco Vaca F, Slimane M. Effect of PPAR-β/δ agonist GW0742 treatment in the acute phase response and blood-brain barrier permeability following brain injury. Transl Res. 2017;182:27-48 pubmed publisher
  • immunocytochemistry; rat; 1:100; loading ...; fig 3b
  • western blot; rat; 1:250; loading ...; fig 3a
Gao Y, Mruk D, Chen H, Lui W, Lee W, Cheng C. Regulation of the blood-testis barrier by a local axis in the testis: role of laminin ?2 in the basement membrane. FASEB J. 2017;31:584-597 pubmed publisher
  • immunohistochemistry; mouse; 1:400; loading ...; fig 6a
  • western blot; mouse; 1:500; loading ...; fig 6b
Gautam J, Zhang X, Yao Y. The role of pericytic laminin in blood brain barrier integrity maintenance. Sci Rep. 2016;6:36450 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 5a
Keppner A, Malsure S, Nobile A, Auberson M, Bonny O, Hummler E. Altered Prostasin (CAP1/Prss8) Expression Favors Inflammation and Tissue Remodeling in DSS-induced Colitis. Inflamm Bowel Dis. 2016;22:2824-2839 pubmed
  • immunocytochemistry; dogs; loading ...; fig 7a
Fujii N, Matsuo Y, Matsunaga T, Endo S, Sakai H, Yamaguchi M, et al. Hypotonic Stress-induced Down-regulation of Claudin-1 and -2 Mediated by Dephosphorylation and Clathrin-dependent Endocytosis in Renal Tubular Epithelial Cells. J Biol Chem. 2016;291:24787-24799 pubmed
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 2c
Choi Y, Maki T, Mandeville E, Koh S, Hayakawa K, Arai K, et al. Dual effects of carbon monoxide on pericytes and neurogenesis in traumatic brain injury. Nat Med. 2016;22:1335-1341 pubmed publisher
  • western blot; human; 1:200; loading ...; fig 3d
Feng X, Zhang D, Wang Y, Fan R, Hong F, Zhang Y, et al. Dopamine enhances duodenal epithelial permeability via the dopamine D5 receptor in rodent. Acta Physiol (Oxf). 2017;220:113-123 pubmed publisher
  • immunocytochemistry; human; 1:300; loading ...; fig 5c
Priya R, Wee K, Budnar S, Gomez G, Yap A, Michael M. Coronin 1B supports RhoA signaling at cell-cell junctions through Myosin II. Cell Cycle. 2016;15:3033-3041 pubmed
  • immunocytochemistry; mouse; loading ...; fig s1b
Balusu S, Van Wonterghem E, De Rycke R, Raemdonck K, Stremersch S, Gevaert K, et al. Identification of a novel mechanism of blood-brain communication during peripheral inflammation via choroid plexus-derived extracellular vesicles. EMBO Mol Med. 2016;8:1162-1183 pubmed publisher
  • immunohistochemistry; mouse; 7 ug/ml; loading ...; tbl s5
  • western blot; mouse; 2 ug/ml; loading ...; tbl s5
de Sousa Rodrigues M, Bekhbat M, Houser M, Chang J, Walker D, Jones D, et al. Chronic psychological stress and high-fat high-fructose diet disrupt metabolic and inflammatory gene networks in the brain, liver, and gut and promote behavioral deficits in mice. Brain Behav Immun. 2017;59:158-172 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 7c
Wegwitz F, Lenfert E, Gerstel D, von Ehrenstein L, Einhoff J, Schmidt G, et al. CEACAM1 controls the EMT switch in murine mammary carcinoma in vitro and in vivo. Oncotarget. 2016;7:63730-63746 pubmed publisher
  • western blot; mouse; 1:250; loading ...; fig 7a
Lan A, Blais A, Coelho D, Capron J, Maarouf M, Benamouzig R, et al. Dual effects of a high-protein diet on DSS-treated mice during colitis resolution phase. Am J Physiol Gastrointest Liver Physiol. 2016;311:G624-G633 pubmed publisher
  • immunocytochemistry; rat; 1:100; loading ...; tbl 1
  • western blot; rat; 1:500; loading ...; tbl 1
Li N, Lee W, Cheng C. Overexpression of plastin 3 in Sertoli cells disrupts actin microfilament bundle homeostasis and perturbs the tight junction barrier. Spermatogenesis. 2016;6:e1206353 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 2a
  • western blot; mouse; 1:40; loading ...; fig 4k
Wardill H, Bowen J, Van Sebille Y, Secombe K, Coller J, Ball I, et al. TLR4-Dependent Claudin-1 Internalization and Secretagogue-Mediated Chloride Secretion Regulate Irinotecan-Induced Diarrhea. Mol Cancer Ther. 2016;15:2767-2779 pubmed
  • immunocytochemistry; human; 1:100; fig 3h
Jenny Zhou H, Qin L, Zhang H, Tang W, Ji W, He Y, et al. Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation. Nat Med. 2016;22:1033-1042 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 1a
  • western blot; human; loading ...; fig 1d
Wilkinson E, Sidaway J, Cross M. Cardiotoxic drugs Herceptin and doxorubicin inhibit cardiac microvascular endothelial cell barrier formation resulting in increased drug permeability. Biol Open. 2016;5:1362-1370 pubmed publisher
  • immunocytochemistry; mouse; 1:200; fig 2a
Thomsen M, Birkelund S, Burkhart A, Stensballe A, Moos T. Synthesis and deposition of basement membrane proteins by primary brain capillary endothelial cells in a murine model of the blood-brain barrier. J Neurochem. 2017;140:741-754 pubmed publisher
  • immunocytochemistry; rat; 1:100; fig 4
  • western blot; rat; 1:500; fig 2
Li N, Mruk D, Chen H, Wong C, Lee W, Cheng C. Rescue of perfluorooctanesulfonate (PFOS)-mediated Sertoli cell injury by overexpression of gap junction protein connexin 43. Sci Rep. 2016;6:29667 pubmed publisher
  • immunocytochemistry; mouse; fig 2
Iwasaki Y, Sugita S, Mandai M, Yonemura S, Onishi A, Ito S, et al. Differentiation/Purification Protocol for Retinal Pigment Epithelium from Mouse Induced Pluripotent Stem Cells as a Research Tool. PLoS ONE. 2016;11:e0158282 pubmed publisher
  • western blot; rat; 1:250; fig 5
Gao Y, Lui W, Lee W, Cheng C. Polarity protein Crumbs homolog-3 (CRB3) regulates ectoplasmic specialization dynamics through its action on F-actin organization in Sertoli cells. Sci Rep. 2016;6:28589 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 1b
Velandia Romero M, Calderón Peláez M, Castellanos J. In Vitro Infection with Dengue Virus Induces Changes in the Structure and Function of the Mouse Brain Endothelium. PLoS ONE. 2016;11:e0157786 pubmed publisher
  • western blot; mouse; 1:500; fig 6
Campos Y, Qiu X, Gomero E, Wakefield R, Horner L, Brutkowski W, et al. Alix-mediated assembly of the actomyosin-tight junction polarity complex preserves epithelial polarity and epithelial barrier. Nat Commun. 2016;7:11876 pubmed publisher
  • immunocytochemistry; human; 1:50; loading ...; fig 5b
  • western blot; human; loading ...; fig 5a
Priego N, Arechederra M, Sequera C, Bragado P, Vázquez Carballo A, Gutierrez Uzquiza A, et al. C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38? activation, while it impairs tumor growth through p38?-independent mechanisms. Oncotarget. 2016;7:45060-45078 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:25; fig 1
  • immunocytochemistry; mouse; 1:25; fig 2
Bai H, Zhu Q, Surcel A, Luo T, Ren Y, Guan B, et al. Yes-associated protein impacts adherens junction assembly through regulating actin cytoskeleton organization. Am J Physiol Gastrointest Liver Physiol. 2016;311:G396-411 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 3
  • immunohistochemistry - paraffin section; human; fig 3
Lehner C, Gehwolf R, Ek J, Korntner S, Bauer H, Bauer H, et al. The blood-tendon barrier: identification and characterisation of a novel tissue barrier in tendon blood vessels. Eur Cell Mater. 2016;31:296-311 pubmed
  • immunohistochemistry; mouse; fig s2
Baker L, BeGora M, Au Yeung F, Feigin M, Rosenberg A, Lowe S, et al. Scribble is required for pregnancy-induced alveologenesis in the adult mammary gland. J Cell Sci. 2016;129:2307-15 pubmed publisher
  • immunocytochemistry; human; fig 3
Ding H, Xu Y, Gao D, Wang L. Glioma-associated oncogene homolog 1 promotes epithelial-mesenchymal transition in human renal tubular epithelial cell. Am J Transl Res. 2016;8:662-9 pubmed
  • immunocytochemistry; human; fig 3
  • western blot; human; 1:1000; fig 3
  • immunocytochemistry; pigs ; fig 3
  • western blot; pigs ; 1:1000; fig 3
Inada M, Izawa G, Kobayashi W, Ozawa M. 293 cells express both epithelial as well as mesenchymal cell adhesion molecules. Int J Mol Med. 2016;37:1521-7 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; fig 3
Kim D, Glendining K, Grattan D, Jasoni C. Maternal Obesity in the Mouse Compromises the Blood-Brain Barrier in the Arcuate Nucleus of Offspring. Endocrinology. 2016;157:2229-42 pubmed publisher
  • western blot; mouse; 1:1000; fig 4
Guerrera D, Shah J, Vasileva E, Sluysmans S, Méan I, Jond L, et al. PLEKHA7 Recruits PDZD11 to Adherens Junctions to Stabilize Nectins. J Biol Chem. 2016;291:11016-29 pubmed publisher
  • immunocytochemistry; dogs; fig 3
Klinkert K, Rocancourt M, Houdusse A, Echard A. Rab35 GTPase couples cell division with initiation of epithelial apico-basal polarity and lumen opening. Nat Commun. 2016;7:11166 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 4
  • western blot; human; 1:250; fig 4
Liu W, Cai H, Lin M, Zhu L, Gao L, Zhong R, et al. MicroRNA-107 prevents amyloid-beta induced blood-brain barrier disruption and endothelial cell dysfunction by targeting Endophilin-1. Exp Cell Res. 2016;343:248-257 pubmed publisher
  • immunocytochemistry; human; fig 4
Wardill H, Gibson R, Van Sebille Y, Secombe K, Logan R, Bowen J. A novel in vitro platform for the study of SN38-induced mucosal damage and the development of Toll-like receptor 4-targeted therapeutic options. Exp Biol Med (Maywood). 2016;241:1386-94 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:300; fig 7
  • western blot; mouse; fig 8
Falcão V, Maschio D, de Fontes C, Oliveira R, Santos Silva J, Almeida A, et al. Reduced insulin secretion function is associated with pancreatic islet redistribution of cell adhesion molecules (CAMS) in diabetic mice after prolonged high-fat diet. Histochem Cell Biol. 2016;146:13-31 pubmed publisher
  • western blot; rat; 1:500; fig 2
Yang C, Demars K, Hawkins K, Candelario Jalil E. Adropin reduces paracellular permeability of rat brain endothelial cells exposed to ischemia-like conditions. Peptides. 2016;81:29-37 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:1000; fig 4
Davey C, Mathewson A, Moens C. PCP Signaling between Migrating Neurons and their Planar-Polarized Neuroepithelial Environment Controls Filopodial Dynamics and Directional Migration. PLoS Genet. 2016;12:e1005934 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 2
Kuehn A, Kletting S, de Souza Carvalho Wodarz C, Repnik U, Griffiths G, Fischer U, et al. Human alveolar epithelial cells expressing tight junctions to model the air-blood barrier. ALTEX. 2016;33:251-60 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 8
Ji X, Liu Y, Hurd R, Wang J, Fitzmaurice B, Nishina P, et al. Retinal Pigment Epithelium Atrophy 1 (rpea1): A New Mouse Model With Retinal Detachment Caused by a Disruption of Protein Kinase C, θ. Invest Ophthalmol Vis Sci. 2016;57:877-88 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 8
Shukla P, Chaudhry K, Mir H, Gangwar R, Yadav N, Manda B, et al. Chronic ethanol feeding promotes azoxymethane and dextran sulfate sodium-induced colonic tumorigenesis potentially by enhancing mucosal inflammation. BMC Cancer. 2016;16:189 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:400; fig 1
Gebala V, Collins R, Geudens I, Phng L, Gerhardt H. Blood flow drives lumen formation by inverse membrane blebbing during angiogenesis in vivo. Nat Cell Biol. 2016;18:443-50 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:50; fig 3
Kai T, Tsukamoto Y, Hijiya N, Tokunaga A, Nakada C, Uchida T, et al. Kidney-specific knockout of Sav1 in the mouse promotes hyperproliferation of renal tubular epithelium through suppression of the Hippo pathway. J Pathol. 2016;239:97-108 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1.25 mg/ml; fig 4
McCabe M, Tarulli G, Laven Law G, Matthiesson K, Meachem S, McLachlan R, et al. Gonadotropin suppression in men leads to a reduction in claudin-11 at the Sertoli cell tight junction. Hum Reprod. 2016;31:875-86 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; fig 3
Skardal A, Devarasetty M, Forsythe S, Atala A, Soker S. A reductionist metastasis-on-a-chip platform for in vitro tumor progression modeling and drug screening. Biotechnol Bioeng. 2016;113:2020-32 pubmed publisher
  • western blot; rat; 1:1000; fig 3
Fang Z, He Q, Li Q, Chen X, Baral S, Jin H, et al. MicroRNA-150 regulates blood-brain barrier permeability via Tie-2 after permanent middle cerebral artery occlusion in rats. FASEB J. 2016;30:2097-107 pubmed publisher
  • immunocytochemistry; rat; 1:100; fig 1
Chojnacka K, Bilinska B, Mruk D. Interleukin 1alpha-induced disruption of the Sertoli cell cytoskeleton affects gap junctional communication. Cell Signal. 2016;28:469-480 pubmed publisher
  • western blot; mouse; 1:300; fig 5
Cai J, Liu W, Hao J, Chen M, Li G. Increased expression of dermatopontin and its implications for testicular dysfunction in mice. Mol Med Rep. 2016;13:2431-8 pubmed publisher
  • immunocytochemistry; mouse; 5 ug/ml; fig 2
Lazarevic I, Engelhardt B. Modeling immune functions of the mouse blood-cerebrospinal fluid barrier in vitro: primary rather than immortalized mouse choroid plexus epithelial cells are suited to study immune cell migration across this brain barrier. Fluids Barriers CNS. 2016;13:2 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 2.5 ug/ml
Gaide Chevronnay H, Janssens V, Van Der Smissen P, Rocca C, Liao X, Refetoff S, et al. Hematopoietic Stem Cells Transplantation Can Normalize Thyroid Function in a Cystinosis Mouse Model. Endocrinology. 2016;157:1363-71 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 2
Salomon J, Spahn S, Wang X, Füllekrug J, Bertrand C, Mall M. Generation and functional characterization of epithelial cells with stable expression of SLC26A9 Cl- channels. Am J Physiol Lung Cell Mol Physiol. 2016;310:L593-602 pubmed publisher
  • western blot; mouse; 1:100; tbl 1
Bertoldo M, Guibert E, Faure M, Guillou F, Ramé C, Nadal Desbarats L, et al. Specific deletion of AMP-activated protein kinase (α1AMPK) in mouse Sertoli cells modifies germ cell quality. Mol Cell Endocrinol. 2016;423:96-112 pubmed publisher
  • western blot; mouse; 1:300; fig 6
Liu Y, Su X, Hao J, Chen M, Liu W, Liao X, et al. Overexpression of PRL7D1 in Leydig Cells Causes Male Reproductive Dysfunction in Mice. Int J Mol Sci. 2016;17: pubmed publisher
  • western blot; rat; fig 8
Yang S, Krug S, Heitmann J, Hu L, Reinhold A, Sauer S, et al. Analgesic drug delivery via recombinant tissue plasminogen activator and microRNA-183-triggered opening of the blood-nerve barrier. Biomaterials. 2016;82:20-33 pubmed publisher
  • immunocytochemistry; human; fig 6
Gonçalves S, Rodrigues I, Padrão J, Silva J, Sencadas V, Lanceros Méndez S, et al. Acetylated bacterial cellulose coated with urinary bladder matrix as a substrate for retinal pigment epithelium. Colloids Surf B Biointerfaces. 2016;139:1-9 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:50; tbl 2
Li N, Mruk D, Mok K, Li M, Wong C, Lee W, et al. Connexin 43 reboots meiosis and reseals blood-testis barrier following toxicant-mediated aspermatogenesis and barrier disruption. FASEB J. 2016;30:1436-52 pubmed publisher
  • immunohistochemistry - paraffin section; dogs; 1:400; fig 1
Kim H, Cronin M, Ahrens K, Papastavros V, Santoro D, Marsella R. A comparative study of epidermal tight junction proteins in a dog model of atopic dermatitis. Vet Dermatol. 2016;27:40-e11 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 3
Heuser S, Hufbauer M, Marx B, Tok A, Majewski S, Pfister H, et al. The levels of epithelial anchor proteins β-catenin and zona occludens-1 are altered by E7 of human papillomaviruses 5 and 8. J Gen Virol. 2016;97:463-72 pubmed publisher
  • immunocytochemistry; mouse; fig 5e
Yoshie S, Imaizumi M, Nakamura R, Otsuki K, Ikeda M, Nomoto Y, et al. Generation of airway epithelial cells with native characteristics from mouse induced pluripotent stem cells. Cell Tissue Res. 2016;364:319-30 pubmed publisher
  • immunohistochemistry; human
Wardill H, Logan R, Bowen J, Van Sebille Y, Gibson R. Tight junction defects are seen in the buccal mucosa of patients receiving standard dose chemotherapy for cancer. Support Care Cancer. 2016;24:1779-88 pubmed publisher
  • immunocytochemistry; human
Kasper J, Hermanns M, Unger R, Kirkpatrick C. A responsive human triple-culture model of the air-blood barrier: incorporation of different macrophage phenotypes. J Tissue Eng Regen Med. 2017;11:1285-1297 pubmed publisher
  • western blot; human; 1:500
Islam S, Mokhtari R, Noman A, Uddin M, Rahman M, Azadi M, et al. Sonic hedgehog (Shh) signaling promotes tumorigenicity and stemness via activation of epithelial-to-mesenchymal transition (EMT) in bladder cancer. Mol Carcinog. 2016;55:537-51 pubmed publisher
Kusakabe R, Higuchi S, Tanaka M, Kadota M, Nishimura O, Kuratani S. Novel developmental bases for the evolution of hypobranchial muscles in vertebrates. BMC Biol. 2020;18:120 pubmed publisher
Duarte Lobo D, Nobre R, Oliveira Miranda C, Pereira D, Castelhano J, Sereno J, et al. The blood-brain barrier is disrupted in Machado-Joseph disease/spinocerebellar ataxia type 3: evidence from transgenic mice and human post-mortem samples. Acta Neuropathol Commun. 2020;8:152 pubmed publisher
Devraj G, Guérit S, Seele J, Spitzer D, Macas J, Khel M, et al. HIF-1α is involved in blood-brain barrier dysfunction and paracellular migration of bacteria in pneumococcal meningitis. Acta Neuropathol. 2020;140:183-208 pubmed publisher
Sreekumar P, Wang M, Spee C, Sadda S, Kannan R. Transporter-Mediated Mitochondrial GSH Depletion Leading to Mitochondrial Dysfunction and Rescue with αB Crystallin Peptide in RPE Cells. Antioxidants (Basel). 2020;9: pubmed publisher
Liu Y, Zhang Y, Li T, Han J, Wang Y. The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock. Nat Commun. 2020;11:589 pubmed publisher
Brydon E, Bronstein R, Buskin A, Lako M, Pierce E, Fernandez Godino R. AAV-Mediated Gene Augmentation Therapy Restores Critical Functions in Mutant PRPF31+/- iPSC-Derived RPE Cells. Mol Ther Methods Clin Dev. 2019;15:392-402 pubmed publisher
Mehdizadeh Gohari I, Li J, Navarro M, Uzal F, McClane B. Effects of Claudin-1 on the Action of Clostridium perfringens Enterotoxin in Caco-2 Cells. Toxins (Basel). 2019;11: pubmed publisher
Miranda J, Martín Tapia D, Valdespino Vazquez Y, Alarcón L, Espejel Nuñez A, Guzmán Huerta M, et al. Syncytiotrophoblast of Placentae from Women with Zika Virus Infection Has Altered Tight Junction Protein Expression and Increased Paracellular Permeability. Cells. 2019;8: pubmed publisher
Hurley B, Jugo R, Snow R, Samuels T, Yonker L, Mou H, et al. Pepsin Triggers Neutrophil Migration Across Acid Damaged Lung Epithelium. Sci Rep. 2019;9:13778 pubmed publisher
Wang Q, Deng Y, Huang L, Zeng W, Chen S, Lv B, et al. Hypertonic saline downregulates endothelial cell-derived VEGF expression and reduces blood-brain barrier permeability induced by cerebral ischaemia via the VEGFR2/eNOS pathway. Int J Mol Med. 2019;44:1078-1090 pubmed publisher
Castro Dias M, Coisne C, Baden P, Enzmann G, Garrett L, Becker L, et al. Claudin-12 is not required for blood-brain barrier tight junction function. Fluids Barriers CNS. 2019;16:30 pubmed publisher
Achberger K, Probst C, Haderspeck J, Bolz S, Rogal J, Chuchuy J, et al. Merging organoid and organ-on-a-chip technology to generate complex multi-layer tissue models in a human retina-on-a-chip platform. elife. 2019;8: pubmed publisher
Hsu K, Otsu W, Li Y, Wang H, Chen S, Tsang S, et al. CLIC4 regulates late endosomal trafficking and matrix degradation activity of MMP14 at focal adhesions in RPE cells. Sci Rep. 2019;9:12247 pubmed publisher
Wei H, Sundararaman A, Dickson E, Rennie Campbell L, Cross E, Heesom K, et al. Characterization of the polarized endothelial secretome. FASEB J. 2019;33:12277-12287 pubmed publisher
Jónsdóttir H, Marti S, Geerts D, Rodriguez R, Thiel V, Dijkman R. Establishment of Primary Transgenic Human Airway Epithelial Cell Cultures to Study Respiratory Virus-Host Interactions. Viruses. 2019;11: pubmed publisher
Wilson M, Reske J, Holladay J, Wilber G, Rhodes M, Koeman J, et al. ARID1A and PI3-kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion. Nat Commun. 2019;10:3554 pubmed publisher
Yang R, Hui Q, Jiang Q, Liu S, Zhang H, Wu J, et al. Effect of Manitoba-Grown Red-Osier Dogwood Extracts on Recovering Caco-2 Cells from H2O2-Induced Oxidative Damage. Antioxidants (Basel). 2019;8: pubmed publisher
Wu Y, Zhen W, Geng Y, Wang Z, Guo Y. Pretreatment with probiotic Enterococcus faecium NCIMB 11181 ameliorates necrotic enteritis-induced intestinal barrier injury in broiler chickens. Sci Rep. 2019;9:10256 pubmed publisher
Milenkovic A, Schmied D, Tanimoto N, Seeliger M, Sparrow J, Weber B. The Y227N mutation affects bestrophin-1 protein stability and impairs sperm function in a mouse model of Best vitelliform macular dystrophy. Biol Open. 2019;: pubmed publisher
Wen S, Shim R, Ho L, Wanrooy B, Srikhanta Y, Prame Kumar K, et al. Advanced age promotes colonic dysfunction and gut-derived lung infection after stroke. Aging Cell. 2019;18:e12980 pubmed publisher
Haspula D, Vallejos A, Moore T, Tomar N, Dash R, Hoffmann B. Influence of a Hyperglycemic Microenvironment on a Diabetic Versus Healthy Rat Vascular Endothelium Reveals Distinguishable Mechanistic and Phenotypic Responses. Front Physiol. 2019;10:558 pubmed publisher
Rosales M, Shu D, Iacovelli J, Saint Geniez M. Loss of PGC-1α in RPE induces mesenchymal transition and promotes retinal degeneration. Life Sci Alliance. 2019;2: pubmed publisher
Zhao Q, Zhang F, Yu Z, Guo S, Liu N, Jiang Y, et al. HDAC3 inhibition prevents blood-brain barrier permeability through Nrf2 activation in type 2 diabetes male mice. J Neuroinflammation. 2019;16:103 pubmed publisher
Nanjundappa R, Kong D, Shim K, Stearns T, Brody S, Loncarek J, et al. Regulation of cilia abundance in multiciliated cells. elife. 2019;8: pubmed publisher
Holwerda M, Kelly J, Laloli L, Stürmer I, Portmann J, Stalder H, et al. Determining the Replication Kinetics and Cellular Tropism of Influenza D Virus on Primary Well-Differentiated Human Airway Epithelial Cells. Viruses. 2019;11: pubmed publisher
Wang X, Zhang J, Li G, Sai N, Han J, Hou Z, et al. Vascular regeneration in adult mouse cochlea stimulated by VEGF-A165 and driven by NG2-derived cells ex vivo. Hear Res. 2019;377:179-188 pubmed publisher
Xu F, Shen G, Su Z, He Z, Yuan L. Glibenclamide ameliorates the disrupted blood-brain barrier in experimental intracerebral hemorrhage by inhibiting the activation of NLRP3 inflammasome. Brain Behav. 2019;9:e01254 pubmed publisher
Li L, Wu S, Yan M, Lian Q, Ge R, Cheng C. Regulation of blood-testis barrier dynamics by the mTORC1/rpS6 signaling complex: An in vitro study. Asian J Androl. 2019;21:365-375 pubmed publisher
Maerz L, Burkhalter M, Schilpp C, Wittekindt O, Frick M, Philipp M. Pharmacological cholesterol depletion disturbs ciliogenesis and ciliary function in developing zebrafish. Commun Biol. 2019;2:31 pubmed publisher
Haarmann A, Schuhmann M, Silwedel C, Monoranu C, Stoll G, Buttmann M. Human Brain Endothelial CXCR2 is Inflammation-Inducible and Mediates CXCL5- and CXCL8-Triggered Paraendothelial Barrier Breakdown. Int J Mol Sci. 2019;20: pubmed publisher
Martin J, Muccioli M, Herman K, Finnell R, Plageman T. Folic acid modifies the shape of epithelial cells during morphogenesis via a Folr1 and MLCK dependent mechanism. Biol Open. 2019;8: pubmed publisher
Cui T, Jiang L, Li T, Teng F, Feng G, Wang X, et al. Derivation of Mouse Haploid Trophoblast Stem Cells. Cell Rep. 2019;26:407-414.e5 pubmed publisher
He S, Guo Y, Zhao J, Xu X, Song J, Wang N, et al. Ferulic acid protects against heat stress-induced intestinal epithelial barrier dysfunction in IEC-6 cells via the PI3K/Akt-mediated Nrf2/HO-1 signaling pathway. Int J Hyperthermia. 2019;35:112-121 pubmed publisher
Kobayakawa Y, Masaki K, Yamasaki R, Shiraishi W, Hayashida S, Hayashi S, et al. Downregulation of Neuronal and Dendritic Connexin36-Made Electrical Synapses Without Glutamatergic Axon Terminals in Spinal Anterior Horn Cells From the Early Stage of Amyotrophic Lateral Sclerosis. Front Neurosci. 2018;12:894 pubmed publisher
Suryavanshi N, Furmston J, Ridley A. The STRIPAK complex components FAM40A and FAM40B regulate endothelial cell contractility via ROCKs. BMC Cell Biol. 2018;19:26 pubmed publisher
Marques M, Melo J, Cavadas B, Mendes N, Pereira L, Carneiro F, et al. Afadin Downregulation by Helicobacter pylori Induces Epithelial to Mesenchymal Transition in Gastric Cells. Front Microbiol. 2018;9:2712 pubmed publisher
Miller D, Bloxham R, Jiang M, Gori I, Saunders R, Das D, et al. The Dynamics of TGF-β Signaling Are Dictated by Receptor Trafficking via the ESCRT Machinery. Cell Rep. 2018;25:1841-1855.e5 pubmed publisher
Liu J, Huang C, Peng C, Xu F, Li Y, Yutaka Y, et al. Stromal fibroblast activation protein alpha promotes gastric cancer progression via epithelial-mesenchymal transition through Wnt/ β-catenin pathway. BMC Cancer. 2018;18:1099 pubmed publisher
Chen H, Lu R, Zhang Y, Sun J. Vitamin D Receptor Deletion Leads to the Destruction of Tight and Adherens Junctions in Lungs. Tissue Barriers. 2018;6:1-13 pubmed publisher
Song C, Kim N, Sohn S, Lee S, Nam R, Na H, et al. Effects of 17β-Estradiol on Colonic Permeability and Inflammation in an Azoxymethane/Dextran Sulfate Sodium-Induced Colitis Mouse Model. Gut Liver. 2018;12:682-693 pubmed publisher
Shukla P, Meena A, Rao V, Rao R, Balazs L, Rao R. Human Defensin-5 Blocks Ethanol and Colitis-Induced Dysbiosis, Tight Junction Disruption and Inflammation in Mouse Intestine. Sci Rep. 2018;8:16241 pubmed publisher
Hashi K, Imai C, Yahara K, Tahmina K, Hayashi T, Azuma T, et al. Evaluating the origin and virulence of a Helicobacter pylori cagA-positive strain isolated from a non-human primate. Sci Rep. 2018;8:15981 pubmed publisher
Falero Perez J, Song Y, Zhao Y, Teixeira L, Sorenson C, Sheibani N. Cyp1b1 expression impacts the angiogenic and inflammatory properties of liver sinusoidal endothelial cells. PLoS ONE. 2018;13:e0206756 pubmed publisher
Mosa M, Nicolle O, Maschalidi S, Sepulveda F, Bidaud Meynard A, Menche C, et al. Dynamic Formation of Microvillus Inclusions During Enterocyte Differentiation in Munc18-2-Deficient Intestinal Organoids. Cell Mol Gastroenterol Hepatol. 2018;6:477-493.e1 pubmed publisher
Mehta S, Tom C, Wang Y, Bresee C, Rushton D, Mathkar P, et al. Human Huntington's Disease iPSC-Derived Cortical Neurons Display Altered Transcriptomics, Morphology, and Maturation. Cell Rep. 2018;25:1081-1096.e6 pubmed publisher
Dong B, Vold S, Olvera Jaramillo C, Chang H. Functional redundancy of frizzled 3 and frizzled 6 in planar cell polarity control of mouse hair follicles. Development. 2018;145: pubmed publisher
Knouse K, Lopez K, Bachofner M, Amon A. Chromosome Segregation Fidelity in Epithelia Requires Tissue Architecture. Cell. 2018;175:200-211.e13 pubmed publisher
Vormann M, Gijzen L, Hutter S, Boot L, Nicolas A, van den Heuvel A, et al. Nephrotoxicity and Kidney Transport Assessment on 3D Perfused Proximal Tubules. AAPS J. 2018;20:90 pubmed publisher
Saxena M, Kalathur R, Neutzner M, Christofori G. PyMT-1099, a versatile murine cell model for EMT in breast cancer. Sci Rep. 2018;8:12123 pubmed publisher
Zhu H, Dai R, Zhou Y, Fu H, Meng Q. TLR2 Ligand Pam3CSK4 Regulates MMP-2/9 Expression by MAPK/NF-κB Signaling Pathways in Primary Brain Microvascular Endothelial Cells. Neurochem Res. 2018;43:1897-1904 pubmed publisher
Yang Y, Huang C, Lin X, Wu Y, Ouyang W, Tang L, et al. 0.005% Preservative-Free Latanoprost Induces Dry Eye-Like Ocular Surface Damage via Promotion of Inflammation in Mice. Invest Ophthalmol Vis Sci. 2018;59:3375-3384 pubmed publisher
Gril B, Paranjape A, Woditschka S, Hua E, Dolan E, Hanson J, et al. Reactive astrocytic S1P3 signaling modulates the blood-tumor barrier in brain metastases. Nat Commun. 2018;9:2705 pubmed publisher
Zhao M, Xiong X, Ren K, Xu B, Cheng M, Sahu C, et al. Deficiency in intestinal epithelial O-GlcNAcylation predisposes to gut inflammation. EMBO Mol Med. 2018;10: pubmed publisher
Brunse A, Abbaspour A, Sangild P. Brain Barrier Disruption and Region-Specific Neuronal Degeneration during Necrotizing Enterocolitis in Preterm Pigs. Dev Neurosci. 2018;40:198-208 pubmed publisher
Pollock L, Xie J, Bell B, Anand Apte B. Retinoic acid signaling is essential for maintenance of the blood-retinal barrier. FASEB J. 2018;32:5674-5684 pubmed publisher
Wang J, Lee E, Ji M, Park S. HDAC inhibitors, trichostatin A and valproic acid, increase E‑cadherin and vimentin expression but inhibit migration and invasion of cholangiocarcinoma cells. Oncol Rep. 2018;40:346-354 pubmed publisher
Muroyama A, Terwilliger M, Dong B, Suh H, Lechler T. Genetically induced microtubule disruption in the mouse intestine impairs intracellular organization and transport. Mol Biol Cell. 2018;29:1533-1541 pubmed publisher
Benhamouche Trouillet S, O Loughlin E, Liu C, Polacheck W, Fitamant J, McKee M, et al. Proliferation-independent role of NF2 (merlin) in limiting biliary morphogenesis. Development. 2018;145: pubmed publisher
Takahashi C, Miyatake K, Kusakabe M, Nishida E. The atypical mitogen-activated protein kinase ERK3 is essential for establishment of epithelial architecture. J Biol Chem. 2018;293:8342-8361 pubmed publisher
Toyama K, Spin J, Deng A, Huang T, Wei K, Wagenhäuser M, et al. MicroRNA-Mediated Therapy Modulating Blood-Brain Barrier Disruption Improves Vascular Cognitive Impairment. Arterioscler Thromb Vasc Biol. 2018;38:1392-1406 pubmed publisher
Poppe D, Doerr J, Schneider M, Wilkens R, Steinbeck J, Ladewig J, et al. Genome Editing in Neuroepithelial Stem Cells to Generate Human Neurons with High Adenosine-Releasing Capacity. Stem Cells Transl Med. 2018;7:477-486 pubmed publisher
Clayton A, Shao Q, Paauw N, Giambrone A, Granger J, Warrington J. Postpartum increases in cerebral edema and inflammation in response to placental ischemia during pregnancy. Brain Behav Immun. 2018;70:376-389 pubmed publisher
Demars K, McCrea A, Siwarski D, Sanz B, Yang C, Candelario Jalil E. Protective Effects of L-902,688, a Prostanoid EP4 Receptor Agonist, against Acute Blood-Brain Barrier Damage in Experimental Ischemic Stroke. Front Neurosci. 2018;12:89 pubmed publisher
Kim S, Zhang S, Werner M, Brotslaw E, Mitchell J, Altabbaa M, et al. CLAMP/Spef1 regulates planar cell polarity signaling and asymmetric microtubule accumulation in the Xenopus ciliated epithelia. J Cell Biol. 2018;217:1633-1641 pubmed publisher
Li S, Ning K, Zhou J, Guo Y, Zhang H, Zhu Y, et al. Sleep deprivation disrupts the lacrimal system and induces dry eye disease. Exp Mol Med. 2018;50:e451 pubmed publisher
Singh A, Sharma S, Pagarware K, Siraji R, Ansari I, Mandal A, et al. Enteropathogenic E. coli effectors EspF and Map independently disrupt tight junctions through distinct mechanisms involving transcriptional and post-transcriptional regulation. Sci Rep. 2018;8:3719 pubmed publisher
Ayehunie S, Landry T, Stevens Z, Armento A, Hayden P, Klausner M. Human Primary Cell-Based Organotypic Microtissues for Modeling Small Intestinal Drug Absorption. Pharm Res. 2018;35:72 pubmed publisher
Marie M, Bigot K, Angebault C, Barrau C, Gondouin P, Pagan D, et al. Light action spectrum on oxidative stress and mitochondrial damage in A2E-loaded retinal pigment epithelium cells. Cell Death Dis. 2018;9:287 pubmed publisher
Sakakibara S, Maruo T, Miyata M, Mizutani K, Takai Y. Requirement of the F-actin-binding activity of l-afadin for enhancing the formation of adherens and tight junctions. Genes Cells. 2018;23:185-199 pubmed publisher
Kanda Y, Yamasaki Y, Sasaki Yamaguchi Y, Ida Koga N, Kamisuki S, Sugawara F, et al. TRPA1-dependent reversible opening of tight junction by natural compounds with an α,β-unsaturated moiety and capsaicin. Sci Rep. 2018;8:2251 pubmed publisher
Mincheva M, Sandhowe Klaverkamp R, Wistuba J, Redmann K, Stukenborg J, Kliesch S, et al. Reassembly of adult human testicular cells: can testis cord-like structures be created in vitro?. Mol Hum Reprod. 2018;24:55-63 pubmed publisher
Boucherie C, Boutin C, Jossin Y, Schakman O, Goffinet A, Ris L, et al. Neural progenitor fate decision defects, cortical hypoplasia and behavioral impairment in Celsr1-deficient mice. Mol Psychiatry. 2018;23:723-734 pubmed publisher
Schnabolk G, Parsons N, Obert E, Annamalai B, Nasarre C, Tomlinson S, et al. Delivery of CR2-fH Using AAV Vector Therapy as Treatment Strategy in the Mouse Model of Choroidal Neovascularization. Mol Ther Methods Clin Dev. 2018;9:1-11 pubmed publisher
Zhou S, Gillilland M, Wu X, Leelasinjaroen P, Zhang G, Zhou H, et al. FODMAP diet modulates visceral nociception by lipopolysaccharide-mediated intestinal inflammation and barrier dysfunction. J Clin Invest. 2018;128:267-280 pubmed publisher
Van Sebille Y, Gibson R, Wardill H, Ball I, Keefe D, Bowen J. Dacomitinib-induced diarrhea: Targeting chloride secretion with crofelemer. Int J Cancer. 2018;142:369-380 pubmed publisher
Izawa Y, Gu Y, Osada T, Kanazawa M, Hawkins B, Koziol J, et al. β1-integrin-matrix interactions modulate cerebral microvessel endothelial cell tight junction expression and permeability. J Cereb Blood Flow Metab. 2018;38:641-658 pubmed publisher
Li S, Zhou J, Zhang L, Li J, Yu J, Ning K, et al. Ectodysplasin A regulates epithelial barrier function through sonic hedgehog signalling pathway. J Cell Mol Med. 2018;22:230-240 pubmed publisher
Yu J, Li C, Ding Q, Que J, Liu K, Wang H, et al. Netrin-1 Ameliorates Blood-Brain Barrier Impairment Secondary to Ischemic Stroke via the Activation of PI3K Pathway. Front Neurosci. 2017;11:700 pubmed publisher
Jaworska K, Huc T, Samborowska E, Dobrowolski L, Bielinska K, Gawlak M, et al. Hypertension in rats is associated with an increased permeability of the colon to TMA, a gut bacteria metabolite. PLoS ONE. 2017;12:e0189310 pubmed publisher
Li X, Zhang Y, Wang X, Jin C, Wang Y, Sun T, et al. Regulation of blood-testis barrier assembly in vivo by germ cells. FASEB J. 2017;: pubmed publisher
Wu D, Huang C, Jiao X, Ding Z, Zhang J, Chen F, et al. Olaquindox disrupts tight junction integrity and cytoskeleton architecture in mouse Sertoli cells. Oncotarget. 2017;8:88630-88644 pubmed publisher
Sahu S, Tiwari N, Pataskar A, Zhuang Y, Borisova M, Diken M, et al. FBXO32 promotes microenvironment underlying epithelial-mesenchymal transition via CtBP1 during tumour metastasis and brain development. Nat Commun. 2017;8:1523 pubmed publisher
Mahajan S, Thieme D, Czugala M, Kruse F, Fuchsluger T. Lamin Cleavage: A Reliable Marker for Studying Staurosporine-Induced Apoptosis in Corneal Tissue. Invest Ophthalmol Vis Sci. 2017;58:5802-5809 pubmed publisher
Penberthy K, Rival C, Shankman L, Raymond M, Zhang J, Perry J, et al. Context-dependent compensation among phosphatidylserine-recognition receptors. Sci Rep. 2017;7:14623 pubmed publisher
Hassell B, Goyal G, Lee E, Sontheimer Phelps A, Levy O, Chen C, et al. Human Organ Chip Models Recapitulate Orthotopic Lung Cancer Growth, Therapeutic Responses, and Tumor Dormancy In Vitro. Cell Rep. 2017;21:508-516 pubmed publisher
Bugeon S, de Chevigny A, Boutin C, Coré N, Wild S, Bosio A, et al. Direct and efficient transfection of mouse neural stem cells and mature neurons by in vivo mRNA electroporation. Development. 2017;144:3968-3977 pubmed publisher
Lopez Ramirez M, Fonseca G, Zeineddine H, Girard R, Moore T, Pham A, et al. Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations. J Exp Med. 2017;214:3331-3346 pubmed publisher
Fogarty N, McCarthy A, Snijders K, Powell B, Kubikova N, Blakeley P, et al. Genome editing reveals a role for OCT4 in human embryogenesis. Nature. 2017;550:67-73 pubmed publisher
Zhang L, Du S, Lu Y, Liu C, Wu H, Tian Z, et al. Puerarin transport across rat nasal epithelial cells and the influence of compatibility with peoniflorin and menthol. Drug Des Devel Ther. 2017;11:2581-2593 pubmed publisher
Hu Y, Yang B, Xu Y, Jiang L, Tsui C, Liang X. FK506 suppresses hypoxia‑induced inflammation and protects tight junction function via the CaN‑NFATc1 signaling pathway in retinal microvascular epithelial cells. Mol Med Rep. 2017;16:6974-6980 pubmed publisher
De Servi B, Ranzini F, Piqué N. Protective barrier properties of Rhinosectan® spray (containing xyloglucan) on an organotypic 3D airway tissue model (MucilAir): results of an in vitro study. Allergy Asthma Clin Immunol. 2017;13:37 pubmed publisher
Trietsch S, Naumovska E, Kurek D, Setyawati M, Vormann M, Wilschut K, et al. Membrane-free culture and real-time barrier integrity assessment of perfused intestinal epithelium tubes. Nat Commun. 2017;8:262 pubmed publisher
Kämpfer A, Urbán P, Gioria S, Kanase N, Stone V, Kinsner Ovaskainen A. Development of an in vitro co-culture model to mimic the human intestine in healthy and diseased state. Toxicol In Vitro. 2017;45:31-43 pubmed publisher
Chen J, Li Z, Zhang L, Ou S, Wang Y, He X, et al. Descemet's Membrane Supports Corneal Endothelial Cell Regeneration in Rabbits. Sci Rep. 2017;7:6983 pubmed publisher
Sauer R, Kirchner J, Yang S, Hu L, Leinders M, Sommer C, et al. Blood-spinal cord barrier breakdown and pericyte deficiency in peripheral neuropathy. Ann N Y Acad Sci. 2017;1405:71-88 pubmed publisher
Horng S, Therattil A, Moyon S, Gordon A, Kim K, Argaw A, et al. Astrocytic tight junctions control inflammatory CNS lesion pathogenesis. J Clin Invest. 2017;127:3136-3151 pubmed publisher
Bennis A, Jacobs J, Catsburg L, ten Brink J, Koster C, Schlingemann R, et al. Stem Cell Derived Retinal Pigment Epithelium: The Role of Pigmentation as Maturation Marker and Gene Expression Profile Comparison with Human Endogenous Retinal Pigment Epithelium. Stem Cell Rev. 2017;13:659-669 pubmed publisher
Lewis M, Merrifield C, Berger B, Cloarec O, Duncker S, Mercenier A, et al. Early intervention with Bifidobacterium lactis NCC2818 modulates the host-microbe interface independent of the sustained changes induced by the neonatal environment. Sci Rep. 2017;7:5310 pubmed publisher
Zhang J, Wang Y, Chen J, Zhang X, Dong J, Tsang L, et al. Defective CFTR leads to aberrant β-catenin activation and kidney fibrosis. Sci Rep. 2017;7:5233 pubmed publisher
Ly H, Verma N, Wu F, Liu M, Saatman K, Nelson P, et al. Brain microvascular injury and white matter disease provoked by diabetes-associated hyperamylinemia. Ann Neurol. 2017;82:208-222 pubmed publisher
Durgan J, Tseng Y, Hamann J, Domart M, Collinson L, Hall A, et al. Mitosis can drive cell cannibalism through entosis. elife. 2017;6: pubmed publisher
Wu J, Han W, Chen X, Guo W, Liu K, Wang R, et al. Matrix metalloproteinase-2 and -9 contribute to functional integrity and noise‑induced damage to the blood-labyrinth-barrier. Mol Med Rep. 2017;16:1731-1738 pubmed publisher
Vasileva E, Sluysmans S, Bochaton Piallat M, Citi S. Cell-specific diversity in the expression and organization of cytoplasmic plaque proteins of apical junctions. Ann N Y Acad Sci. 2017;1405:160-176 pubmed publisher
van Dijk I, Ferrando M, van der Wijk A, Hoebe R, Nazmi K, de Jonge W, et al. Human salivary peptide histatin-1 stimulates epithelial and endothelial cell adhesion and barrier function. FASEB J. 2017;31:3922-3933 pubmed publisher
Zaritsky A, Tseng Y, Rabadán M, Krishna S, Overholtzer M, Danuser G, et al. Diverse roles of guanine nucleotide exchange factors in regulating collective cell migration. J Cell Biol. 2017;216:1543-1556 pubmed publisher
Park D, Lee J, Kim J, Kim K, Hong S, Han S, et al. Plastic roles of pericytes in the blood-retinal barrier. Nat Commun. 2017;8:15296 pubmed publisher
Wolf M, Maltseva I, Clay S, Pan P, Gajjala A, Chan M. Effects of MMP12 on cell motility and inflammation during corneal epithelial repair. Exp Eye Res. 2017;160:11-20 pubmed publisher
Navandar M, Garding A, Sahu S, Pataskar A, Schick S, Tiwari V. ERK signalling modulates epigenome to drive epithelial to mesenchymal transition. Oncotarget. 2017;8:29269-29281 pubmed publisher
Shiotani H, Maruo T, Sakakibara S, Miyata M, Mandai K, Mochizuki H, et al. Aging-dependent expression of synapse-related proteins in the mouse brain. Genes Cells. 2017;22:472-484 pubmed publisher
Meng Y, Cai K, Moore R, Tao W, Tse J, Smith E, et al. Pten facilitates epiblast epithelial polarization and proamniotic lumen formation in early mouse embryos. Dev Dyn. 2017;246:517-530 pubmed publisher
Lenis T, Sarfare S, Jiang Z, Lloyd M, Bok D, Radu R. Complement modulation in the retinal pigment epithelium rescues photoreceptor degeneration in a mouse model of Stargardt disease. Proc Natl Acad Sci U S A. 2017;114:3987-3992 pubmed publisher
Xiao J, Yao J, Jia L, Lin C, Zacks D. Protective Effect of Met12, a Small Peptide Inhibitor of Fas, on the Retinal Pigment Epithelium and Photoreceptor After Sodium Iodate Injury. Invest Ophthalmol Vis Sci. 2017;58:1801-1810 pubmed publisher
Melo M, Moraes Borges R, Yan C. Par3 in chick lens placode development. Genesis. 2017;55: pubmed publisher
Burkhart A, Andresen T, Aigner A, Thomsen L, Moos T. Transfection of primary brain capillary endothelial cells for protein synthesis and secretion of recombinant erythropoietin: a strategy to enable protein delivery to the brain. Cell Mol Life Sci. 2017;74:2467-2485 pubmed publisher
Yu H, Xue Y, Wang P, Liu X, Ma J, Zheng J, et al. Knockdown of long non-coding RNA XIST increases blood-tumor barrier permeability and inhibits glioma angiogenesis by targeting miR-137. Oncogenesis. 2017;6:e303 pubmed publisher
Bruno J, Nicolas A, Pesenti S, Schwarz J, Simon J, Leonil J, et al. Variants of ?-casofensin, a bioactive milk peptide, differently modulate the intestinal barrier: In vivo and ex vivo studies in rats. J Dairy Sci. 2017;100:3360-3372 pubmed publisher
González Tarragó V, Elosegui Artola A, Bazellieres E, Oria R, Pérez González C, Roca Cusachs P. Binding of ZO-1 to ?5?1 integrins regulates the mechanical properties of ?5?1-fibronectin links. Mol Biol Cell. 2017;28:1847-1852 pubmed publisher
Pourabdolhossein F, Gil Perotin S, Garcia Belda P, Dauphin A, Mozafari S, Tepavcevic V, et al. Inflammatory demyelination induces ependymal modifications concomitant to activation of adult (SVZ) stem cell proliferation. Glia. 2017;65:756-772 pubmed publisher
Nighot P, Leung L, Ma T. Chloride channel ClC- 2 enhances intestinal epithelial tight junction barrier function via regulation of caveolin-1 and caveolar trafficking of occludin. Exp Cell Res. 2017;352:113-122 pubmed publisher
Obert E, Strauss R, Brandon C, Grek C, Ghatnekar G, GOURDIE R, et al. Targeting the tight junction protein, zonula occludens-1, with the connexin43 mimetic peptide, αCT1, reduces VEGF-dependent RPE pathophysiology. J Mol Med (Berl). 2017;95:535-552 pubmed publisher
Rolland Fourcade C, Denadai Souza A, Cirillo C, Lopez C, Jaramillo J, Desormeaux C, et al. Epithelial expression and function of trypsin-3 in irritable bowel syndrome. Gut. 2017;66:1767-1778 pubmed publisher
Mohaddes G, Abdolalizadeh J, Babri S, Hossienzadeh F. Ghrelin ameliorates blood-brain barrier disruption during systemic hypoxia. Exp Physiol. 2017;102:376-382 pubmed publisher
Baek A, Yoon S, Kim J, Baek Y, Park H, Lim D, et al. Autophagy and KRT8/keratin 8 protect degeneration of retinal pigment epithelium under oxidative stress. Autophagy. 2017;13:248-263 pubmed publisher
Kasper J, Hermanns M, Cavelius C, Kraegeloh A, Jung T, Danzebrink R, et al. The role of the intestinal microvasculature in inflammatory bowel disease: studies with a modified Caco-2 model including endothelial cells resembling the intestinal barrier in vitro. Int J Nanomedicine. 2016;11:6353-6364 pubmed
Reiling J, Bridle K, Gijbels M, Schaap F, Jaskowski L, Santrampurwala N, et al. Low-Dose Lipopolysaccharide Causes Biliary Injury by Blood Biliary Barrier Impairment in a Rat Hepatic Ischemia/Reperfusion Model. Liver Transpl. 2017;23:194-206 pubmed publisher
Gaddipati S, Rao P, Jerome A, Burugula B, Gerard N, Suvas S. Loss of Neurokinin-1 Receptor Alters Ocular Surface Homeostasis and Promotes an Early Development of Herpes Stromal Keratitis. J Immunol. 2016;197:4021-4033 pubmed
Baisantry A, Bhayana S, Wrede C, Hegermann J, Haller H, Melk A, et al. The impact of autophagy on the development of senescence in primary tubular epithelial cells. Cell Cycle. 2016;15:2973-2979 pubmed
Feinberg T, Rowe R, Saunders T, Weiss S. Functional roles of MMP14 and MMP15 in early postnatal mammary gland development. Development. 2016;143:3956-3968 pubmed
Jorgens D, Inman J, Wojcik M, Robertson C, Palsdottir H, Tsai W, et al. Deep nuclear invaginations are linked to cytoskeletal filaments - integrated bioimaging of epithelial cells in 3D culture. J Cell Sci. 2017;130:177-189 pubmed publisher
Maugeri G, D Amico A, Gagliano C, Saccone S, Federico C, Cavallaro S, et al. VIP Family Members Prevent Outer Blood Retinal Barrier Damage in a Model of Diabetic Macular Edema. J Cell Physiol. 2017;232:1079-1085 pubmed publisher
Brinkmann B, Steinbacher T, Hartmann C, Kummer D, Pajonczyk D, Mirzapourshafiyi F, et al. VE-cadherin interacts with cell polarity protein Pals1 to regulate vascular lumen formation. Mol Biol Cell. 2016;27:2811-21 pubmed publisher
Montorsi L, Guizzetti F, Alecci C, Caporali A, Martello A, Atene C, et al. Loss of ZFP36 expression in colorectal cancer correlates to wnt/ ß-catenin activity and enhances epithelial-to-mesenchymal transition through upregulation of ZEB1, SOX9 and MACC1. Oncotarget. 2016;7:59144-59157 pubmed publisher
Nair V, Franco L, Zacharia V, Khan H, Stamm C, YOU W, et al. Microfold Cells Actively Translocate Mycobacterium tuberculosis to Initiate Infection. Cell Rep. 2016;16:1253-1258 pubmed publisher
Maeta K, Edamatsu H, Nishihara K, Ikutomo J, Bilasy S, Kataoka T. Crucial Role of Rapgef2 and Rapgef6, a Family of Guanine Nucleotide Exchange Factors for Rap1 Small GTPase, in Formation of Apical Surface Adherens Junctions and Neural Progenitor Development in the Mouse Cerebral Cortex. Eneuro. 2016;3: pubmed publisher
Raman R, Damle I, Rote R, Banerjee S, Dingare C, Sonawane M. aPKC regulates apical localization of Lgl to restrict elongation of microridges in developing zebrafish epidermis. Nat Commun. 2016;7:11643 pubmed publisher
Alluri H, Wilson R, Anasooya Shaji C, Wiggins Dohlvik K, Patel S, Liu Y, et al. Melatonin Preserves Blood-Brain Barrier Integrity and Permeability via Matrix Metalloproteinase-9 Inhibition. PLoS ONE. 2016;11:e0154427 pubmed publisher
Lotz Jenne C, Lüthi U, Ackerknecht S, Lehembre F, Fink T, Stritt M, et al. A high-content EMT screen identifies multiple receptor tyrosine kinase inhibitors with activity on TGFβ receptor. Oncotarget. 2016;7:25983-6002 pubmed publisher
Chen H, Mruk D, Lee W, Cheng C. Planar Cell Polarity (PCP) Protein Vangl2 Regulates Ectoplasmic Specialization Dynamics via Its Effects on Actin Microfilaments in the Testes of Male Rats. Endocrinology. 2016;157:2140-59 pubmed publisher
Drolez A, Vandenhaute E, Julien S, Gosselet F, Burchell J, Cecchelli R, et al. Selection of a Relevant In Vitro Blood-Brain Barrier Model to Investigate Pro-Metastatic Features of Human Breast Cancer Cell Lines. PLoS ONE. 2016;11:e0151155 pubmed publisher
Sreekanthreddy P, Gromnicova R, Davies H, Phillips J, Romero I, Male D. A three-dimensional model of the human blood-brain barrier to analyse the transport of nanoparticles and astrocyte/endothelial interactions. F1000Res. 2015;4:1279 pubmed publisher
Raredon M, Ghaedi M, Calle E, Niklason L. A Rotating Bioreactor for Scalable Culture and Differentiation of Respiratory Epithelium. Cell Med. 2015;7:109-21 pubmed publisher
Frankowski J, Demars K, Ahmad A, Hawkins K, Yang C, Leclerc J, et al. Detrimental role of the EP1 prostanoid receptor in blood-brain barrier damage following experimental ischemic stroke. Sci Rep. 2015;5:17956 pubmed publisher
Heller J, Kwok J, Vecino E, Martin K, Fawcett J. A Method for the Isolation and Culture of Adult Rat Retinal Pigment Epithelial (RPE) Cells to Study Retinal Diseases. Front Cell Neurosci. 2015;9:449 pubmed publisher
Bergen A, Kaing S, ten Brink J, Gorgels T, Janssen S. Gene expression and functional annotation of human choroid plexus epithelium failure in Alzheimer's disease. BMC Genomics. 2015;16:956 pubmed publisher
Su L, Zhang Y, Cheng Y, Lee W, Ye K, Hu D. Slc15a1 is involved in the transport of synthetic F5-peptide into the seminiferous epithelium in adult rat testes. Sci Rep. 2015;5:16271 pubmed publisher
Huang L, Holtzinger A, Jagan I, BeGora M, Lohse I, Ngai N, et al. Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell- and patient-derived tumor organoids. Nat Med. 2015;21:1364-71 pubmed publisher
Bizet A, Becker Heck A, Ryan R, Weber K, Filhol E, Krug P, et al. Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization. Nat Commun. 2015;6:8666 pubmed publisher
Martínez Revollar G, Garay E, Martín Tapia D, Nava P, Huerta M, Lopez Bayghen E, et al. Heterogeneity between triple negative breast cancer cells due to differential activation of Wnt and PI3K/AKT pathways. Exp Cell Res. 2015;339:67-80 pubmed publisher
Dang Y, Wu W, Xu Y, Mu Y, Xu K, Wu H, et al. Effects of low-level laser irradiation on proliferation and functional protein expression in human RPE cells. Lasers Med Sci. 2015;30:2295-302 pubmed publisher
Pearson H, McGlinn E, Phesse T, Schlüter H, Srikumar A, Gödde N, et al. The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis. Mol Cancer. 2015;14:169 pubmed publisher
Priya R, Gomez G, Budnar S, Verma S, Cox H, Hamilton N, et al. Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions. Nat Cell Biol. 2015;17:1282-93 pubmed publisher
Zhao Y, Zhao L, Wang P, Miao Y, Liu Y, Wang Z, et al. Overexpression of miR-18a negatively regulates myocyte enhancer factor 2D to increase the permeability of the blood-tumor barrier via Krüppel-like factor 4-mediated downregulation of zonula occluden-1, claudin-5, and occludin. J Neurosci Res. 2015;93:1891-902 pubmed publisher
Shirato K, Ujike M, Kawase M, Matsuyama S. Identification of CCL2, RARRES2 and EFNB2 as host cell factors that influence the multistep replication of respiratory syncytial virus. Virus Res. 2015;210:213-26 pubmed publisher
Singh B, Bogatcheva G, Starchenko A, Sinnaeve J, Lapierre L, Williams J, et al. Induction of lateral lumens through disruption of a monoleucine-based basolateral-sorting motif in betacellulin. J Cell Sci. 2015;128:3444-55 pubmed publisher
Sivaraj K, Li R, Albarrán Juárez J, Wang S, Tischner D, Grimm M, et al. Endothelial Gαq/11 is required for VEGF-induced vascular permeability and angiogenesis. Cardiovasc Res. 2015;108:171-80 pubmed publisher
Liu W, Zhong Z, Cao L, Li H, Zhang T, Lin W. Paclitaxel-induced lung injury and its amelioration by parecoxib sodium. Sci Rep. 2015;5:12977 pubmed publisher
Burkhart A, Thomsen L, Thomsen M, Lichota J, Fazakas C, Krizbai I, et al. Transfection of brain capillary endothelial cells in primary culture with defined blood-brain barrier properties. Fluids Barriers CNS. 2015;12:19 pubmed publisher
Thomsen L, Burkhart A, Moos T. A Triple Culture Model of the Blood-Brain Barrier Using Porcine Brain Endothelial cells, Astrocytes and Pericytes. PLoS ONE. 2015;10:e0134765 pubmed publisher
Kim J, Ko A, Hyun H, Kang T. ETB receptor-mediated MMP-9 activation induces vasogenic edema via ZO-1 protein degradation following status epilepticus. Neuroscience. 2015;304:355-67 pubmed publisher
Sahu S, Garding A, Tiwari N, Thakurela S, Toedling J, Gebhard S, et al. JNK-dependent gene regulatory circuitry governs mesenchymal fate. EMBO J. 2015;34:2162-81 pubmed publisher
Chang C, Lin C, Lu C, Martel J, Ko Y, Ojcius D, et al. Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota. Nat Commun. 2015;6:7489 pubmed publisher
Ek C, D Angelo B, Lehner C, Nathanielsz P, Li C, Mallard C. Expression of tight junction proteins and transporters for xenobiotic metabolism at the blood-CSF barrier during development in the nonhuman primate (P. hamadryas). Reprod Toxicol. 2015;56:32-44 pubmed publisher
Cai H, Xue Y, Wang P, Wang Z, Li Z, Hu Y, et al. The long noncoding RNA TUG1 regulates blood-tumor barrier permeability by targeting miR-144. Oncotarget. 2015;6:19759-79 pubmed
Rode K, Sieme H, Richterich P, Brehm R. Characterization of the equine blood-testis barrier during tubular development in normal and cryptorchid stallions. Theriogenology. 2015;84:763-72 pubmed publisher
Li N, Mruk D, Wong C, Lee W, Han D, Cheng C. Actin-bundling protein plastin 3 is a regulator of ectoplasmic specialization dynamics during spermatogenesis in the rat testis. FASEB J. 2015;29:3788-805 pubmed publisher
Suárez Causado A, Caballero Díaz D, Bertrán E, Roncero C, Addante A, García Álvaro M, et al. HGF/c-Met signaling promotes liver progenitor cell migration and invasion by an epithelial-mesenchymal transition-independent, phosphatidyl inositol-3 kinase-dependent pathway in an in vitro model. Biochim Biophys Acta. 2015;1853:2453-63 pubmed publisher
Kim B, Hancock B, Bermudez A, Del Cid N, Reyes E, van Sorge N, et al. Bacterial induction of Snail1 contributes to blood-brain barrier disruption. J Clin Invest. 2015;125:2473-83 pubmed publisher
Son Y, Heo K, Bae M, Lee C, Cho W, Kim S, et al. Injury to the blood-testis barrier after low-dose-rate chronic radiation exposure in mice. Radiat Prot Dosimetry. 2015;167:316-20 pubmed publisher
Breznau E, Semack A, Higashi T, Miller A. MgcRacGAP restricts active RhoA at the cytokinetic furrow and both RhoA and Rac1 at cell-cell junctions in epithelial cells. Mol Biol Cell. 2015;26:2439-55 pubmed publisher
Ghatak S, Chan Y, Khanna S, Banerjee J, Weist J, Roy S, et al. Barrier Function of the Repaired Skin Is Disrupted Following Arrest of Dicer in Keratinocytes. Mol Ther. 2015;23:1201-1210 pubmed publisher
Giribaldi M, Muñoz A, Halvorsen K, Patel A, Rai P. MTH1 expression is required for effective transformation by oncogenic HRAS. Oncotarget. 2015;6:11519-29 pubmed
Charest J, Okamoto T, Kitano K, Yasuda A, Gilpin S, Mathisen D, et al. Design and validation of a clinical-scale bioreactor for long-term isolated lung culture. Biomaterials. 2015;52:79-87 pubmed publisher
Zhang J, Chen S, Hou Z, Cai J, Dong M, Shi X. Lipopolysaccharide-induced middle ear inflammation disrupts the cochlear intra-strial fluid-blood barrier through down-regulation of tight junction proteins. PLoS ONE. 2015;10:e0122572 pubmed publisher
Bazellières E, Conte V, Elosegui Artola A, Serra Picamal X, Bintanel Morcillo M, Roca Cusachs P, et al. Control of cell-cell forces and collective cell dynamics by the intercellular adhesome. Nat Cell Biol. 2015;17:409-20 pubmed publisher
Freeman J, Feng Y, Demehri F, Dempsey P, Teitelbaum D. TPN-associated intestinal epithelial cell atrophy is modulated by TLR4/EGF signaling pathways. FASEB J. 2015;29:2943-58 pubmed publisher
Melo E, Kasper J, Unger R, Farré R, Kirkpatrick C. Development of a Bronchial Wall Model: Triple Culture on a Decellularized Porcine Trachea. Tissue Eng Part C Methods. 2015;21:909-21 pubmed publisher
Skardal A, Devarasetty M, Rodman C, Atala A, Soker S. Liver-Tumor Hybrid Organoids for Modeling Tumor Growth and Drug Response In Vitro. Ann Biomed Eng. 2015;43:2361-73 pubmed publisher
Hue C, Cho F, Cao S, Dale Bass C, Meaney D, Morrison B. Dexamethasone potentiates in vitro blood-brain barrier recovery after primary blast injury by glucocorticoid receptor-mediated upregulation of ZO-1 tight junction protein. J Cereb Blood Flow Metab. 2015;35:1191-8 pubmed publisher
Walker M, Evock Clover C, Elsasser T, Connor E. Short communication: Glucagon-like peptide-2 and coccidiosis alter tight junction gene expression in the gastrointestinal tract of dairy calves. J Dairy Sci. 2015;98:3432-7 pubmed publisher
ErLin S, WenJie W, LiNing W, BingXin L, MingDe L, Yan S, et al. Musashi-1 maintains blood-testis barrier structure during spermatogenesis and regulates stress granule formation upon heat stress. Mol Biol Cell. 2015;26:1947-56 pubmed publisher
Wu J, Peng D, Zhang Y, Lu Z, Voehler M, Sanders C, et al. Biophysical characterization of interactions between the C-termini of peripheral nerve claudins and the PDZ₁ domain of zonula occludens. Biochem Biophys Res Commun. 2015;459:87-93 pubmed publisher
Licht T, Dor Wollman T, Ben Zvi A, Rothe G, Keshet E. Vessel maturation schedule determines vulnerability to neuronal injuries of prematurity. J Clin Invest. 2015;125:1319-28 pubmed publisher
Benoit B, Laugerette F, Plaisancié P, Géloën A, Bodennec J, Estienne M, et al. Increasing fat content from 20 to 45 wt% in a complex diet induces lower endotoxemia in parallel with an increased number of intestinal goblet cells in mice. Nutr Res. 2015;35:346-56 pubmed publisher
Narita K, Sasamoto S, Koizumi S, Okazaki S, Nakamura H, Inoue T, et al. TRPV4 regulates the integrity of the blood-cerebrospinal fluid barrier and modulates transepithelial protein transport. FASEB J. 2015;29:2247-59 pubmed publisher
Ohlemacher S, Iglesias C, Sridhar A, Gamm D, Meyer J. Generation of highly enriched populations of optic vesicle-like retinal cells from human pluripotent stem cells. Curr Protoc Stem Cell Biol. 2015;32:1H.8.1-20 pubmed publisher
Hauser P, Vangordon S, Seavey J, Sofinowski T, Ramadan M, Abdullah S, et al. Abnormalities in Expression of Structural, Barrier and Differentiation Related Proteins, and Chondroitin Sulfate in Feline and Human Interstitial Cystitis. J Urol. 2015;194:571-7 pubmed publisher
Ek C, D Angelo B, Baburamani A, Lehner C, Leverin A, Smith P, et al. Brain barrier properties and cerebral blood flow in neonatal mice exposed to cerebral hypoxia-ischemia. J Cereb Blood Flow Metab. 2015;35:818-27 pubmed publisher
Boatright J, Dalal N, Chrenek M, Gardner C, Ziesel A, Jiang Y, et al. Methodologies for analysis of patterning in the mouse RPE sheet. Mol Vis. 2015;21:40-60 pubmed
Suzuki T, Kono T, Bochimoto H, Hira Y, Watanabe T, Furukawa H. An injured tissue affects the opposite intact peritoneum during postoperative adhesion formation. Sci Rep. 2015;5:7668 pubmed publisher
Park D, Cerrone M, Morley G, Vasquez C, Fowler S, Liu N, et al. Genetically engineered SCN5A mutant pig hearts exhibit conduction defects and arrhythmias. J Clin Invest. 2015;125:403-12 pubmed publisher
Cai H, Liu W, Xue Y, Shang X, Liu J, Li Z, et al. Roundabout 4 regulates blood-tumor barrier permeability through the modulation of ZO-1, Occludin, and Claudin-5 expression. J Neuropathol Exp Neurol. 2015;74:25-37 pubmed publisher
Tang E, Mok K, Lee W, Cheng C. EB1 regulates tubulin and actin cytoskeletal networks at the sertoli cell blood-testis barrier in male rats: an in vitro study. Endocrinology. 2015;156:680-93 pubmed publisher
Kapodistria K, Tsilibary E, Politis P, Moustardas P, Charonis A, Kitsiou P. Nephrin, a transmembrane protein, is involved in pancreatic beta-cell survival signaling. Mol Cell Endocrinol. 2015;400:112-28 pubmed publisher
Kim K, Ossipova O, Sokol S. Neural crest specification by inhibition of the ROCK/Myosin II pathway. Stem Cells. 2015;33:674-85 pubmed publisher
Petridou N, Skourides P. FAK transduces extracellular forces that orient the mitotic spindle and control tissue morphogenesis. Nat Commun. 2014;5:5240 pubmed publisher
Casselbrant A, Elias E, Fändriks L, Wallenius V. Expression of tight-junction proteins in human proximal small intestinal mucosa before and after Roux-en-Y gastric bypass surgery. Surg Obes Relat Dis. 2015;11:45-53 pubmed publisher
García Hernández V, Flores Maldonado C, Rincon Heredia R, Verdejo Torres O, Bonilla Delgado J, Meneses Morales I, et al. EGF regulates claudin-2 and -4 expression through Src and STAT3 in MDCK cells. J Cell Physiol. 2015;230:105-15 pubmed publisher
Retana C, Sanchez E, Perez Lopez A, Cruz A, Lagunas J, Cruz C, et al. Alterations of intercellular junctions in peritoneal mesothelial cells from patients undergoing dialysis: effect of retinoic Acid. Perit Dial Int. 2015;35:275-87 pubmed publisher
Watanabe M, Kang Y, Davies L, Meghpara S, Lau K, Chung C, et al. BMP4 sufficiency to induce choroid plexus epithelial fate from embryonic stem cell-derived neuroepithelial progenitors. J Neurosci. 2012;32:15934-45 pubmed publisher
Rhett J, Jourdan J, Gourdie R. Connexin 43 connexon to gap junction transition is regulated by zonula occludens-1. Mol Biol Cell. 2011;22:1516-28 pubmed publisher
Otani T, Ichii T, Aono S, Takeichi M. Cdc42 GEF Tuba regulates the junctional configuration of simple epithelial cells. J Cell Biol. 2006;175:135-46 pubmed
Janda E, Lehmann K, Killisch I, Jechlinger M, Herzig M, Downward J, et al. Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways. J Cell Biol. 2002;156:299-313 pubmed
product information
Product Type :
Antibody
Product Name :
ZO-1 Polyclonal Antibody
Catalog # :
61-7300
Quantity :
100 µg
Price :
425 USD
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Canine, Guinea Pig, Human, Mouse, Rat
Applications :
ELISA: Assay Dependent, Immunocytochemistry: 5-10 µg/mL, Immunofluorescence: 5-10 µg/mL, Immunohistochemistry: 2-5 µg/mL, Immunoprecipitation: Assay Dependent, Western Blot: 0.5-2 µg/mL
Species :
Canine, Guinea Pig, Human, Mouse, Rat
Isotype :
IgG
Storage :
-20°C
Description :
ZO-1 forms complexes with either ZO-2 or ZO-3. In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction. ZO-1 expression is significantly reduced in many breast cancer lines. ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue. ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. ZO-1 may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for the ZO-1 gene. Diseases associated with ZO-1 dysfunction include Celiac Disease and Congenital Nephrotic Syndrome.
Immunogen :
A 69 kD fusion protein(1) corresponding to amino acids 463-1109 of human ZO-1 cDNA.(2) This sequence lies N-terminal to the 80 amino acid region (the alpha-motif) present in the a+-isoform but absent in the a- isoform due to alternative splicing.
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay Dependent, Immunocytochemistry: 5-10 µg/mL, Immunofluorescence: 5-10 µg/mL, Immunohistochemistry: 2-5 µg/mL, Immunoprecipitation: Assay Dependent, Western Blot: 0.5-2 µg/mL
Aliases :
DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); tight junction protein ZO-1; TJP1; zo1; ZO-1; zona occludens 1; zona occludens protein 1; zonula occludens 1; zonula occludens 1 protein; zonula occludens protein 1
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA