IL-2 Monoclonal Antibody (MQ1-17H12), PE-eFluor 610, eBioscience | Invitrogen 61-7029-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IL-2 Monoclonal Antibody (MQ1-17H12), PE-eFluor 610, eBioscience

catalog :

61-7029-42

quantity :

100 Tests

price :

US 447.00

clonality :

monoclonal

host :

rat

conjugate :

PE-eFluor 610

clone name :

MQ1-17H12

The same clone is also sold as:

Bio-Rad: MCA1553PE, MCA1553, MCA1553F, MCA1553A647, MCA1553A488
OriGene: SM2088P, SM2088R, SM2088F
BioLegend: 500363, 500354, 500348, 500359, 500306, 500353, 500314, 500350, 500325, 500307, 500345, 500309, 500333, 500324, 500321, 500331, 500341, 500356, 500346, 500338, 500319, 500322, 500337, 500305, 500362, 500349, 500355, 500361, 500327, 500343, 500339, 500315, 500342, 500351, 500326, 500310, 500352, 500304, 500302, 500320, 500332, 500357, 500311, 500360, 500344, 500328, 500347, 500301, 500334
Wuhan Fine Biotech Co.,Ltd.: PE-30056, FITC-30056, APC-30056
BD Biosciences: 560709, 554566, 554562, 561054, 560708, 554567, 564165, 559334, 560902, 554563, 551383, 560707

reactivity :

human

application :

flow cytometry

citations: 11

Reference
Xia B, Lin K, Wang X, Chen F, Zhou M, Li Y, et al. Nanobody-derived bispecific CAR-T cell therapy enhances the anti-tumor efficacy of T cell lymphoma treatment. Mol Ther Oncolytics. 2023;30:86-102 pubmed publisher
Jeong H, Kim S, Jung M, Noh J, Yoo J, Kim E, et al. Enhanced antibody responses in fully vaccinated individuals against pan-SARS-CoV-2 variants following Omicron breakthrough infection. Cell Rep Med. 2022;3:100764 pubmed publisher
Koerber N, Priller A, Yazici S, Bauer T, Cheng C, Mijočević H, et al. Dynamics of spike-and nucleocapsid specific immunity during long-term follow-up and vaccination of SARS-CoV-2 convalescents. Nat Commun. 2022;13:153 pubmed publisher
Ando M, Kondo T, Tomisato W, Ito M, Shichino S, Srirat T, et al. Rejuvenating Effector/Exhausted CAR T Cells to Stem Cell Memory-Like CAR T Cells By Resting Them in the Presence of CXCL12 and the NOTCH Ligand. Cancer Res Commun. 2021;1:41-55 pubmed publisher
Kathamuthu G, Kumar N, Moideen K, Menon P, Babu S. Decreased Frequencies of Gamma/Delta T Cells Expressing Th1/Th17 Cytokine, Cytotoxic, and Immune Markers in Latent Tuberculosis-Diabetes/Pre-Diabetes Comorbidity. Front Cell Infect Microbiol. 2021;11:756854 pubmed publisher
Alrubayyi A, Gea Mallorqu xed E, Touizer E, Hameiri Bowen D, Kopycinski J, Charlton B, et al. Characterization of humoral and SARS-CoV-2 specific T cell responses in people living with HIV. Nat Commun. 2021;12:5839 pubmed publisher
Wu B, Woo J, Vila P, Jew M, Leung J, Sun Z, et al. NKD2 mediates stimulation-dependent ORAI1 trafficking to augment Ca2+ entry in T cells. Cell Rep. 2021;36:109603 pubmed publisher
Asgari A, Lesyk G, Poitras E, Govindasamy N, Terry K, To R, et al. Platelets stimulate programmed death-ligand 1 expression by cancer cells: Inhibition by anti-platelet drugs. J Thromb Haemost. 2021;19:2862-2872 pubmed publisher
Preece R, Pavesi A, Gkazi S, Stegmann K, Georgiadis C, Tan Z, et al. CRISPR-Mediated Base Conversion Allows Discriminatory Depletion of Endogenous T Cell Receptors for Enhanced Synthetic Immunity. Mol Ther Methods Clin Dev. 2020;19:149-161 pubmed publisher
De Luca R, Kachel P, Kropivšek K, Snijder B, Manz M, Neri D. A novel dual-cytokine-antibody fusion protein for the treatment of CD38-positive malignancies. Protein Eng Des Sel. 2018;31:173-179 pubmed publisher
Carpier J, Zucchetti A, Bataille L, Dogniaux S, Shafaq Zadah M, Bardin S, et al. Rab6-dependent retrograde traffic of LAT controls immune synapse formation and T cell activation. J Exp Med. 2018;215:1245-1265 pubmed publisher

product information

Product Type :

Antibody

Product Name :

IL-2 Monoclonal Antibody (MQ1-17H12), PE-eFluor 610, eBioscience

Catalog # :

61-7029-42

Quantity :

100 Tests

Price :

US 447.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (0.125 ug)/test

Species :

Human

Clone :

MQ1-17H12

Isotype :

IgG2a, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.125 ug)/test

Aliases :

aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF