Phosphotyrosine Polyclonal Antibody | Invitrogen 61-5800 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phosphotyrosine Polyclonal Antibody

catalog :

61-5800

quantity :

100 ug

price :

US 451.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

application :

western blot, ELISA, immunoprecipitation

citations: 11

Reference
MacLean I, Varma A, Storey K. Purification and characterization of NADP-isocitrate dehydrogenase from skeletal muscle of Urocitellus richardsonii. Mol Cell Biochem. 2023;478:415-426 pubmed publisher
Yang Y, Yao M, Zeng J, Zheng D, Li Q, Ni Y, et al. FYN regulates cell adhesion at the blood-testis barrier and the apical ectoplasmic specialization via its effect on Arp3 in the mouse testis. Front Immunol. 2022;13:915274 pubmed publisher
Bakovic A, Bhalla N, Kortchak S, Sun C, Zhou W, Ahmed A, et al. Venezuelan Equine Encephalitis Virus nsP3 Phosphorylation Can Be Mediated by IKKβ Kinase Activity and Abrogation of Phosphorylation Inhibits Negative-Strand Synthesis. Viruses. 2020;12: pubmed publisher
Li K, Sun P, Wang Y, Gao T, Zheng D, Liu A, et al. Hsp90 interacts with Cdc37, is phosphorylated by PKA/PKC, and regulates Src phosphorylation in human sperm capacitation. Andrology. 2021;9:185-195 pubmed publisher
Wu J, Song D, Li Z, Guo B, Xiao Y, Liu W, et al. Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis. Cell Res. 2020;30:794-809 pubmed publisher
Arcones A, Cruces Sande M, Ramos P, Mayor F, Murga C. Sex Differences in High Fat Diet-Induced Metabolic Alterations Correlate with Changes in the Modulation of GRK2 Levels. Cells. 2019;8: pubmed publisher
Li B, Ferreira M, Huang M, Camargos L, Yu X, Teixeira R, et al. The receptor-like kinase NIK1 targets FLS2/BAK1 immune complex and inversely modulates antiviral and antibacterial immunity. Nat Commun. 2019;10:4996 pubmed publisher
Mattice A, MacLean I, Childers C, Storey K. -Characterization of pyruvate kinase from the anoxia tolerant turtle, Trachemys scripta elegans: a potential role for enzyme methylation during metabolic rate depression. Peerj. 2018;6:e4918 pubmed publisher
Dawson N, Storey K. Passive regeneration of glutathione: glutathione reductase regulation in the freeze-tolerant North American wood frog, Rana sylvatica. J Exp Biol. 2017;220:3162-3171 pubmed publisher
Dawson N, Katzenback B, Storey K. Free-radical first responders: the characterization of CuZnSOD and MnSOD regulation during freezing of the freeze-tolerant North American wood frog, Rana sylvatica. Biochim Biophys Acta. 2015;1850:97-106 pubmed publisher
Zhang X, Zhang Q, Tu J, Zhu Y, Yang F, Liu B, et al. Prosurvival NMDA 2A receptor signaling mediates postconditioning neuroprotection in the hippocampus. Hippocampus. 2015;25:286-96 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Phosphotyrosine Polyclonal Antibody

Catalog # :

61-5800

Quantity :

100 ug

Price :

US 451.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Chemical

Applications :

ELISA: 1:5,000-1:10,000, Immunoprecipitation: 2-5 ug, Western Blot: 1:1,000-1:2,000

Species :

Chemical

Isotype :

IgG

Storage :

-20 C

Description :

The role of tyrosine phosphorylation in transduction of the mitogenic signal from transmembrane receptors and in transformation by oncogene tyrosine kinases has been the subject of intense investigation for several years. While the phosphorylation of specific tyrosine residues has been shown to be a primary mechanism of signal transduction during normal mitogenesis, cell cycle progression and oncogenic transformation, its role in other areas such as differentiation and gap junction communication, is a matter of active and ongoing research. Antibodies that specifically recognize phosphorylated tyrosine residues have proved to be invaluable to the study of tyrosine -phosphorylated proteins and the biochemical pathways in which they function. The fluorescein (FITC) conjugate of clone PY20 anti-phosphotyrosine is especially useful for the detection of these P-Tyr proteins in immunohistochemical and immunocytochemical protocols in situations wherein the use of a secondary antibody would complicate detection of the protein(s) of interest.

Immunogen :

Affinity-purified native tyrosine phosphorylated proteins.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:5,000-1:10,000, Immunoprecipitation: 2-5 ug, Western Blot: 1:1,000-1:2,000

Aliases :

Phosphotyrosine; pTyr; pY