EOMES Monoclonal Antibody (WD1928), PE-eFluor 610, eBioscience | Invitrogen 61-4877-42 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

EOMES Monoclonal Antibody (WD1928), PE-eFluor 610, eBioscience

catalog :

61-4877-42

quantity :

100 Tests

price :

US 493.00

clonality :

monoclonal

host :

mouse

conjugate :

PE-eFluor 610

clone name :

WD1928

reactivity :

human, pigs

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 35

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 1:100; loading ...	Mathew D, Giles J, Baxter A, Greenplate A, Wu J, Alanio C, et al. Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions. bioRxiv. 2020;: pubmed publisher
	Gicobi J, Mao Z, DeFranco G, Hirdler J, Li Y, Vianzon V, et al. Salvage therapy expands highly cytotoxic and metabolically fit resilient CD8+ T cells via ME1 up-regulation. Sci Adv. 2023;9:eadi2414 pubmed publisher
	Wei H, Li Y, Guo Z, Ma X, Li Y, Wei X, et al. Comparison of dynamic changes in the peripheral CD8+ T cells function and differentiation in ESCC patients treated with radiotherapy combined with anti-PD-1 antibody or concurrent chemoradiotherapy. Front Immunol. 2022;13:1060695 pubmed publisher
	Wildner N, Walker A, Brauneck F, Ditt V, Peine S, Huber S, et al. Transcriptional Pattern Analysis of Virus-Specific CD8+ T Cells in Hepatitis C Infection: Increased Expression of TOX and Eomesodermin During and After Persistent Antigen Recognition. Front Immunol. 2022;13:886646 pubmed publisher
	Kourtis N, Wang Q, Wang B, Oswald E, Adler C, Cherravuru S, et al. A single-cell map of dynamic chromatin landscapes of immune cells in renal cell carcinoma. Nat Cancer. 2022;3:885-898 pubmed publisher
	McMurray J, von Borstel A, Taher T, Syrimi E, Taylor G, Sharif M, et al. Transcriptional profiling of human Vδ1 T cells reveals a pathogen-driven adaptive differentiation program. Cell Rep. 2022;39:110858 pubmed publisher
	Lutter L, Roosenboom B, Brand E, Ter Linde J, Oldenburg B, Van Lochem E, et al. Homeostatic Function and Inflammatory Activation of Ileal CD8+ Tissue-Resident T Cells Is Dependent on Mucosal Location. Cell Mol Gastroenterol Hepatol. 2021;12:1567-1581 pubmed publisher
	Sia W, Hey Y, Foo R, Wang L, Leeansyah E. Culture, expansion, and flow-cytometry-based functional analysis of pteropid bat MR1-restricted unconventional T cells. STAR Protoc. 2021;2:100487 pubmed publisher
	Pattekar A, Mayer L, Lau C, Liu C, Palko O, Bewtra M, et al. Norovirus-Specific CD8+ T Cell Responses in Human Blood and Tissues. Cell Mol Gastroenterol Hepatol. 2021;11:1267-1289 pubmed publisher
	Song M, Pebworth M, Yang X, Abnousi A, Fan C, Wen J, et al. Cell-type-specific 3D epigenomes in the developing human cortex. Nature. 2020;587:644-649 pubmed publisher
	Tao L, Farooq M, Gao Y, Zhang L, Niu C, Ajmal I, et al. CD19-CAR-T Cells Bearing a KIR/PD-1-Based Inhibitory CAR Eradicate CD19+HLA-C1- Malignant B Cells While Sparing CD19+HLA-C1+ Healthy B Cells. Cancers (Basel). 2020;12: pubmed publisher
	Bhattacharya P, Ellegård R, Khalid M, Svanberg C, Govender M, Keita A, et al. Complement opsonization of HIV affects primary infection of human colorectal mucosa and subsequent activation of T cells. elife. 2020;9: pubmed publisher
	Papagno L, Kuse N, Lissina A, Gostick E, Price D, Appay V, et al. The TLR9 ligand CpG ODN 2006 is a poor adjuvant for the induction of de novo CD8+ T-cell responses in vitro. Sci Rep. 2020;10:11620 pubmed publisher
	Bennstein S, Weinhold S, Manser A, Scherenschlich N, Noll A, Raba K, et al. Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR+NKG2A- NK cells. elife. 2020;9: pubmed publisher
	Wragg K, Tan H, Kristensen A, Nguyen Robertson C, Kelleher A, Parsons M, et al. High CD26 and Low CD94 Expression Identifies an IL-23 Responsive Vδ2+ T Cell Subset with a MAIT Cell-like Transcriptional Profile. Cell Rep. 2020;31:107773 pubmed publisher
	Beltra J, Manne S, Abdel Hakeem M, Kurachi M, Giles J, Chen Z, et al. Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms. Immunity. 2020;52:825-841.e8 pubmed publisher
	Yoshida T, Ichikawa J, Giuroiu I, Laino A, Hao Y, Krogsgaard M, et al. C reactive protein impairs adaptive immunity in immune cells of patients with melanoma. J Immunother Cancer. 2020;8: pubmed publisher
	Katsuyama E, Suárez Fueyo A, Bradley S, Mizui M, Marin A, Mulki L, et al. The CD38/NAD/SIRTUIN1/EZH2 Axis Mitigates Cytotoxic CD8 T Cell Function and Identifies Patients with SLE Prone to Infections. Cell Rep. 2020;30:112-123.e4 pubmed publisher
	Cuff A, Sillito F, Dertschnig S, Hall A, Luong T, Chakraverty R, et al. The Obese Liver Environment Mediates Conversion of NK Cells to a Less Cytotoxic ILC1-Like Phenotype. Front Immunol. 2019;10:2180 pubmed publisher
	Marquardt N, Kekäläinen E, Chen P, Lourda M, Wilson J, Scharenberg M, et al. Unique transcriptional and protein-expression signature in human lung tissue-resident NK cells. Nat Commun. 2019;10:3841 pubmed publisher
	Sagebiel A, Steinert F, Lunemann S, Korner C, Schreurs R, Altfeld M, et al. Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine. Nat Commun. 2019;10:975 pubmed publisher
	Sponaas A, Yang R, Rustad E, Standal T, Thoresen A, Dao Vo C, et al. PD1 is expressed on exhausted T cells as well as virus specific memory CD8+ T cells in the bone marrow of myeloma patients. Oncotarget. 2018;9:32024-32035 pubmed publisher
	Kiniry B, Li S, Ganesh A, Hunt P, Somsouk M, Skinner P, et al. Detection of HIV-1-specific gastrointestinal tissue resident CD8+ T-cells in chronic infection. Mucosal Immunol. 2017;: pubmed publisher
	Collins A, Rothman N, Liu K, Reiner S. Eomesodermin and T-bet mark developmentally distinct human natural killer cells. JCI Insight. 2017;2:e90063 pubmed publisher
	Kiniry B, Ganesh A, Critchfield J, Hunt P, Hecht F, Somsouk M, et al. Predominance of weakly cytotoxic, T-betLowEomesNeg CD8+ T-cells in human gastrointestinal mucosa: implications for HIV infection. Mucosal Immunol. 2017;10:1008-1020 pubmed publisher
	Cuff A, Robertson F, Stegmann K, Pallett L, Maini M, Davidson B, et al. Eomeshi NK Cells in Human Liver Are Long-Lived and Do Not Recirculate but Can Be Replenished from the Circulation. J Immunol. 2016;197:4283-4291 pubmed
	Soh K, Tario J, Colligan S, Maguire O, Pan D, Minderman H, et al. Simultaneous, Single-Cell Measurement of Messenger RNA, Cell Surface Proteins, and Intracellular Proteins. Curr Protoc Cytom. 2016;75:7.45.1-7.45.33 pubmed publisher
	Narayanan S, Silva R, Peruzzi G, Alvarez Y, Simhadri V, DeBell K, et al. Human Th1 cells that express CD300a are polyfunctional and after stimulation up-regulate the T-box transcription factor eomesodermin. PLoS ONE. 2010;5:e10636 pubmed publisher
	Intlekofer A, Banerjee A, Takemoto N, Gordon S, Dejong C, Shin H, et al. Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin. Science. 2008;321:408-11 pubmed publisher
	Intlekofer A, Takemoto N, Wherry E, Longworth S, Northrup J, Palanivel V, et al. Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin. Nat Immunol. 2005;6:1236-44 pubmed
	Pearce E, Mullen A, Martins G, Krawczyk C, Hutchins A, Zediak V, et al. Control of effector CD8+ T cell function by the transcription factor Eomesodermin. Science. 2003;302:1041-3 pubmed
	Russ A, Wattler S, Colledge W, Aparicio S, Carlton M, Pearce J, et al. Eomesodermin is required for mouse trophoblast development and mesoderm formation. Nature. 2000;404:95-9 pubmed
	Hancock S, Agulnik S, Silver L, Papaioannou V. Mapping and expression analysis of the mouse ortholog of Xenopus Eomesodermin. Mech Dev. 1999;81:205-8 pubmed
	Ciruna B, Rossant J. Expression of the T-box gene Eomesodermin during early mouse development. Mech Dev. 1999;81:199-203 pubmed
	Ryan K, Garrett N, Mitchell A, Gurdon J. Eomesodermin, a key early gene in Xenopus mesoderm differentiation. Cell. 1996;87:989-1000 pubmed

product information

Product Type :

Antibody

Product Name :

EOMES Monoclonal Antibody (WD1928), PE-eFluor 610, eBioscience

Catalog # :

61-4877-42

Quantity :

100 Tests

Price :

US 493.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human, Porcine

Applications :

Flow Cytometry: 5 uL (0.125 ug)/test

Species :

Human, Porcine

Clone :

WD1928

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

TBR2 is a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similiar protein disrupted in mice is shown to be essential during trophoblast development and gastrulation. TBR2 plays a role in brain development and is required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.125 ug)/test

Aliases :

C77258; EOMES; eomesodermin; eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; T-box transcription factor; TBR2; TBR-2; T-brain-2

more info or order :

Invitrogen product webpage