CD63 Monoclonal Antibody (H5C6), PE-eFluor 610, eBioscience | Invitrogen 61-0639-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD63 Monoclonal Antibody (H5C6), PE-eFluor 610, eBioscience

catalog :

61-0639-42

quantity :

100 Tests

price :

US 418.00

clonality :

monoclonal

host :

mouse

conjugate :

PE-eFluor 610

clone name :

H5C6

The same clone is also sold as:

Novus Biologicals: NBP2-80654, NBP2-42225
BioLegend: 353038, 353009, 353008, 353048, 353051, 353025, 353005, 353006, 353045, 353033, 353047, 353049, 353037, 353003, 353043, 353004, 353018, 353023, 353054, 353015, 353031, 353040, 353016, 353029, 353011, 353056, 353046, 353017, 353027, 353039, 353030, 353044, 353020, 353021, 353041, 353042, 353028, 353026, 353035, 353055, 353012, 353034, 353010, 353024, 353022, 353019, 353032, 353007, 353053
Developmental Studies Hybridoma Bank: H5C6
BD Biosciences: 557305, 557288, 561924, 556019, 556020, 550759, 561925, 561984

reactivity :

human

application :

flow cytometry

citations: 6

Reference
Lu G, Su X, Wang L, Leung C, Zhou J, Xiong Z, et al. Neuroprotective Effects of Human-Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cell Extracellular Vesicles in Ischemic Stroke Models. Biomedicines. 2023;11: pubmed publisher
Sunartvanichkul T, Arayapisit T, Sangkhamanee S, Chaweewannakorn C, Iwasaki K, Klaihmon P, et al. Stem cell-derived exosomes from human exfoliated deciduous teeth promote angiogenesis in hyperglycemic-induced human umbilical vein endothelial cells. J Appl Oral Sci. 2023;31:e20220427 pubmed publisher
Zhao G, Ding L, Yu H, Wang W, Wang H, Hu Y, et al. M2-like tumor-associated macrophages transmit exosomal miR-27b-3p and maintain glioblastoma stem-like cell properties. Cell Death Discov. 2022;8:350 pubmed publisher
Xia W, Lu Z, Chen W, Zhou J, Zhao Y. Excess fatty acids induce pancreatic acinar cell pyroptosis through macrophage M1 polarization. BMC Gastroenterol. 2022;22:72 pubmed publisher
Dellett M, Brown E, Guduric Fuchs J, O Connor A, Stitt A, Medina R, et al. MicroRNA-containing extracellular vesicles released from endothelial colony-forming cells modulate angiogenesis during ischaemic retinopathy. J Cell Mol Med. 2017;21:3405-3419 pubmed publisher
Sun H, Yao W, Tang Y, Zhuang W, Wu D, Huang S, et al. Urinary exosomes as a novel biomarker for evaluation of α-lipoic acid's protective effect in early diabetic nephropathy. J Clin Lab Anal. 2017;31: pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD63 Monoclonal Antibody (H5C6), PE-eFluor 610, eBioscience

Catalog # :

61-0639-42

Quantity :

100 Tests

Price :

US 418.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (1.0 ug)/test

Species :

Human

Clone :

H5C6

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CD63 (LAMP-3, lysosome-associated membrane protein-3), a glycoprotein of tetraspanin family, is present in late endosomes, lysosomes and secretory vesicles of various cell types. CD63 is also present in the plasma membrane, usually following cell activation. Hence, CD63 has become a widely used basophil activation marker. In mast cells, however, CD63 exposition does not need their activation. CD63 interacts with integrins and affects phagocytosis and cell migration, it is also involved in H/K-ATPase trafficking regulation of ROMK1 channels. CD63 also serves as a T-cell costimulation molecule. Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas. CD63 is expressed on activated platelets, and is a lysosomal membrane glycoprotein that is translocated to plasma membrane after platelet activation. CD63 is also present in monocytes and macrophages and is weakly expressed on granulocytes, B, and T cells. CD63 is identical to the melanoma-associated antigen which is ME491 and to the platelet antigen PTLGP40. Diseases associated with CD63 dysfunction include melanoma and Hermansky-Pudlak Syndrome.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (1.0 ug)/test

Aliases :

C75951; CD 63; Cd63; CD63 antigen; CD63 antigen (melanoma 1 antigen); Cd63 molecule; CD63 protein; granulophysin; LAMP-3; Lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3; mast cell antigen AD1; ME491; melanoma 1 antigen; melanoma-associated antigen ME491; melanoma-associated antigen MLA1; MLA1; Ocular melanoma-associated antigen; OMA81H; Tetraspanin-30; TSPAN30; tspan-30