This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD38 Monoclonal Antibody (HIT2), PE-eFluor 610, eBioscience
catalog :
61-0389-42
quantity :
100 Tests
price :
US 377.00
clonality :
monoclonal
host :
mouse
conjugate :
PE-eFluor 610
clone name :
HIT2

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
citations: 14
Reference
Consonni F, Durante B, Manfredi M, Bleve A, Pandolfo C, Garlatti V, et al. Immunometabolic interference between cancer and COVID-19. Front Immunol. 2023;14:1168455 pubmed publisher
Yue Y, Cao Y, Mao X, Wang F, Fan P, Qian L, et al. Novel myeloma patient-derived xenograft models unveil the potency of anlotinib to overcome bortezomib resistance. Front Oncol. 2022;12:894279 pubmed publisher
Lee J, Fra Bido S, Burton A, Innocentin S, Hill D, Linterman M. B cell-intrinsic changes with age do not impact antibody-secreting cell formation but delay B cell participation in the germinal centre reaction. Aging Cell. 2022;21:e13692 pubmed publisher
Burkard T, Dreis C, Herrero San Juan M, Huhn M, Weigert A, Pfeilschifter J, et al. Enhanced CXCR4 Expression of Human CD8Low T Lymphocytes Is Driven by S1P4. Front Immunol. 2021;12:668884 pubmed publisher
Singh Y, Trautwein C, Fendel R, Krickeberg N, Berezhnoy G, Bissinger R, et al. SARS-CoV-2 infection paralyzes cytotoxic and metabolic functions of the immune cells. Heliyon. 2021;7:e07147 pubmed publisher
Akidil E, Albanese M, Buschle A, Ruhle A, Pich D, Keppler O, et al. Highly efficient CRISPR-Cas9-mediated gene knockout in primary human B cells for functional genetic studies of Epstein-Barr virus infection. PLoS Pathog. 2021;17:e1009117 pubmed publisher
Kim Y, Kim Y, Kumar A, Kim C, Toth Z, Cho N, et al. Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen dysregulates expression of MCL-1 by targeting FBW7. PLoS Pathog. 2021;17:e1009179 pubmed publisher
Wiseman D, Baker S, Dongre A, Gurashi K, Storer J, Somervaille T, et al. Chronic myelomonocytic leukaemia stem cell transcriptomes anticipate disease morphology and outcome. EBioMedicine. 2020;58:102904 pubmed publisher
Zumaquero E, Stone S, Scharer C, Jenks S, Nellore A, Mousseau B, et al. IFNγ induces epigenetic programming of human T-bethi B cells and promotes TLR7/8 and IL-21 induced differentiation. elife. 2019;8: pubmed publisher
Kong F, Feng B, Zhang H, Rao H, Wang J, Cong X, et al. Abnormal phenotypic features of IgM+B cell subsets in patients with chronic hepatitis C virus infection. Exp Ther Med. 2017;14:1846-1852 pubmed publisher
Douam F, Hrebikova G, Albrecht Y, Sellau J, Sharon Y, Ding Q, et al. Single-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome. Nat Commun. 2017;8:14781 pubmed publisher
Fernandez I, Ooi T, Roy K. Generation of functional, antigen-specific CD8+ human T cells from cord blood stem cells using exogenous Notch and tetramer-TCR signaling. Stem Cells. 2014;32:93-104 pubmed publisher
Radomska H, Alberich Jorda M, Will B, Gonzalez D, Delwel R, Tenen D. Targeting CDK1 promotes FLT3-activated acute myeloid leukemia differentiation through C/EBP?. J Clin Invest. 2012;122:2955-66 pubmed publisher
Horenstein A, Stockinger H, Imhof B, Malavasi F. CD38 binding to human myeloid cells is mediated by mouse and human CD31. Biochem J. 1998;330 ( Pt 3):1129-35 pubmed
product information
Product Type :
Antibody
Product Name :
CD38 Monoclonal Antibody (HIT2), PE-eFluor 610, eBioscience
Catalog # :
61-0389-42
Quantity :
100 Tests
Price :
US 377.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 5 uL (0.125 ug)/test
Species :
Human
Clone :
HIT2
Isotype :
IgG1, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. CD38 functions as a multi-catalytic ectoenzyme serving as ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase and possibly NAD+ glycohydrolase or as a cell surface receptor. Antibodies to CD38 are useful in subtyping of lymphomas and leukemias, detection of plasma cells (i.e. identification of myelomas), and as a marker for activated B and T cells. CD38 participates in cell adhesion, signal transduction and calcium signaling. Further, CD38 is expressed at high levels in the pancreas, liver, kidney, malignant lymphoma and neuroblastoma. Diseases associated with CD38 dysfunction include chronic lymphocytic leukemia and Richter's Syndrome.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 uL (0.125 ug)/test
Aliases :
2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-cyclic-ADP-ribose transferase; ADPRC 1; ADPRC1; ADP-ribosyl cyclase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; Cd38; CD38 antigen; CD38 antigen (ADP-ribosyl cyclase / cyclic ADP-ribose hydrolase); CD38 antigen (p45); CD38 antigen p45; CD38 molecule; CD38H; Cd38-rs1; cluster of differentiation 38; cyclic ADP-ribose hydrolase 1; ecto-nicotinamide adenine dinucleotide glycohydrolase; I-19; NAD(+) nucleosidase; NAD+ nucleosidase; NIM-R5 antigen; T10
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA