product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Ly-6A/E (Sca-1) Monoclonal Antibody (D7), Alexa Fluor 700, eBioscience
catalog :
56-5981-82
quantity :
100 ug
price :
US 381.00
clonality :
monoclonal
host :
rat
conjugate :
AF700
clone name :
D7
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 126
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 1f
Zhou S, Zhang W, Cai G, Ding Y, Wei C, Li S, et al. Myofiber necroptosis promotes muscle stem cell proliferation via releasing Tenascin-C during regeneration. Cell Res. 2020;30:1063-1077 pubmed publisher
  • flow cytometry; mouse; 1:50; loading ...; fig 7a
Ghanem L, Kromer A, Silverman I, Ji X, Gazzara M, Nguyen N, et al. Poly(C)-Binding Protein Pcbp2 Enables Differentiation of Definitive Erythropoiesis by Directing Functional Splicing of the Runx1 Transcript. Mol Cell Biol. 2018;38: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1b
Delong J, Hall A, Konradt C, Coppock G, Park J, Harms Pritchard G, et al. Cytokine- and TCR-Mediated Regulation of T Cell Expression of Ly6C and Sca-1. J Immunol. 2018;200:1761-1770 pubmed publisher
  • flow cytometry; mouse; fig 2
Driskell R, Lichtenberger B, Hoste E, Kretzschmar K, Simons B, Charalambous M, et al. Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013;504:277-281 pubmed publisher
  • flow cytometry; mouse
Kim H, Lee H, Chang Y, Pichavant M, Shore S, Fitzgerald K, et al. Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity. Nat Med. 2014;20:54-61 pubmed publisher
  • flow cytometry; mouse
Satpathy A, Briseño C, Lee J, Ng D, Manieri N, Kc W, et al. Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens. Nat Immunol. 2013;14:937-48 pubmed publisher
Chen F, Chen Z, Wu H, Chen X, Zhan P, Wei Z, et al. Mesenchymal Stem Cell-Derived Exosomes Attenuate Murine Cytomegalovirus-Infected Pneumonia via NF-κB/NLRP3 Signaling Pathway. Viruses. 2024;16: pubmed publisher
Griffin K, Thorpe S, Sebastian A, Hum N, Coonan T, Sagheb I, et al. Engineered bone marrow as a clinically relevant ex vivo model for primary bone cancer research and drug screening. Proc Natl Acad Sci U S A. 2023;120:e2302101120 pubmed publisher
Li N, Wang Y, Wang A, Zhang J, Jia C, Yu C, et al. STS1 and STS2 Phosphatase Inhibitor Baicalein Enhances the Expansion of Hematopoietic and Progenitor Stem Cells and Alleviates 5-Fluorouracil-Induced Myelosuppression. Int J Mol Sci. 2023;24: pubmed publisher
Mitchell C, Verovskaya E, Calero Nieto F, Olson O, Swann J, Wang X, et al. Stromal niche inflammation mediated by IL-1 signalling is a targetable driver of haematopoietic ageing. Nat Cell Biol. 2023;25:30-41 pubmed publisher
Ramadan R, Wouters V, van Neerven S, de Groot N, Garcia T, Muncan V, et al. The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut. Biol Open. 2022;11: pubmed publisher
Vasquez E, Nasreddin N, Valbuena G, Mulholland E, Belnoue Davis H, Eggington H, et al. Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia. Cell Stem Cell. 2022;29:1213-1228.e8 pubmed publisher
Kanazawa S, Okada H, Riu D, Mabuchi Y, Akazawa C, Iwata J, et al. Hematopoietic-Mesenchymal Signals Regulate the Properties of Mesenchymal Stem Cells. Int J Mol Sci. 2022;23: pubmed publisher
Hamid T, Xu Y, Ismahil M, Rokosh G, Jinno M, Zhou G, et al. Cardiac Mesenchymal Stem Cells Promote Fibrosis and Remodeling in Heart Failure: Role of PDGF Signaling. JACC Basic Transl Sci. 2022;7:465-483 pubmed publisher
Frech S, Forsthuber A, Korosec A, Lipp K, Kozumov V, Lichtenberger B. Hedgehog Signaling in Papillary Fibroblasts Is Essential for Hair Follicle Regeneration during Wound Healing. J Invest Dermatol. 2021;: pubmed publisher
Soukup A, Matson D, Liu P, Johnson K, Bresnick E. Conditionally pathogenic genetic variants of a hematopoietic disease-suppressing enhancer. Sci Adv. 2021;7:eabk3521 pubmed publisher
Roy A, Tomaz da Silva M, Bhat R, Bohnert K, Iwawaki T, Kumar A. The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism. elife. 2021;10: pubmed publisher
Ahamad N, Sun Y, Nascimento Da Conceicao V, Xavier Paul Ezhilan C, Natarajan M, Singh B. Differential activation of Ca2+ influx channels modulate stem cell potency, their proliferation/viability and tissue regeneration. NPJ Regen Med. 2021;6:67 pubmed publisher
Kretzschmar K, Boonekamp K, Bleijs M, Asra P, Koomen M, Chuva de Sousa Lopes S, et al. Troy/Tnfrsf19 marks epidermal cells that govern interfollicular epidermal renewal and cornification. Stem Cell Reports. 2021;16:2379-2394 pubmed publisher
Ambrosi T, Sinha R, Steininger H, Hoover M, Murphy M, Koepke L, et al. Distinct skeletal stem cell types orchestrate long bone skeletogenesis. elife. 2021;10: pubmed publisher
Hu Y, Li X, Zhi X, Cong W, Huang B, Chen H, et al. RANKL from bone marrow adipose lineage cells promotes osteoclast formation and bone loss. EMBO Rep. 2021;22:e52481 pubmed publisher
Wang H, Huang Y, Yu M, Yu Y, Li S, Wang H, et al. Muscle regeneration controlled by a designated DNA dioxygenase. Cell Death Dis. 2021;12:535 pubmed publisher
Wei Q, Pinho S, Dong S, Pierce H, Li H, Nakahara F, et al. MAEA is an E3 ubiquitin ligase promoting autophagy and maintenance of haematopoietic stem cells. Nat Commun. 2021;12:2522 pubmed publisher
Xu W, Ni C, Wang Y, Zheng G, Zhang J, Xu Y. Age-related trabecular bone loss is associated with a decline in serum Galectin-1 level. BMC Musculoskelet Disord. 2021;22:394 pubmed publisher
Proietti D, Giordani L, De Bardi M, D Ercole C, Lozanoska Ochser B, Amadio S, et al. Activation of skeletal muscle-resident glial cells upon nerve injury. JCI Insight. 2021;6: pubmed publisher
Matthews B, Novak S, Sbrana F, Funnell J, Cao Y, Buckels E, et al. Heterogeneity of murine periosteum progenitors involved in fracture healing. elife. 2021;10: pubmed publisher
Sávio Silva C, Soinski Sousa P, Simplício Filho A, Bastos R, Beyerstedt S, Rangel E. Therapeutic Potential of Mesenchymal Stem Cells in a Pre-Clinical Model of Diabetic Kidney Disease and Obesity. Int J Mol Sci. 2021;22: pubmed publisher
Montecino Rodriguez E, Dorshkind K. Use of Busulfan to Condition Mice for Bone Marrow Transplantation. STAR Protoc. 2020;1:100159 pubmed publisher
Gao X, Zhang D, Xu C, Li H, Caron K, Frenette P. Nociceptive nerves regulate haematopoietic stem cell mobilization. Nature. 2021;589:591-596 pubmed publisher
Liu J, Qiu X, Lv Y, Zheng C, Dong Y, Dou G, et al. Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages. Stem Cell Res Ther. 2020;11:507 pubmed publisher
Jiang Y, Xu Z, Ma N, Yin L, Hao C, Li J. Effects of signaling pathway inhibitors on hematopoietic stem cells. Mol Med Rep. 2021;23: pubmed publisher
Deng C, Hu C, Ling S, Zhao N, Bao L, Zhou F, et al. Photoreceptor protection by mesenchymal stem cell transplantation identifies exosomal MiR-21 as a therapeutic for retinal degeneration. Cell Death Differ. 2021;28:1041-1061 pubmed publisher
Geng A, Wu T, Cai C, Song W, Wang J, Yu Q, et al. A novel function of R-spondin1 in regulating estrogen receptor expression independent of Wnt/β-catenin signaling. elife. 2020;9: pubmed publisher
Velletri T, Huang Y, Wang Y, Li Q, Hu M, Xie N, et al. Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerin. Cell Death Differ. 2021;28:156-169 pubmed publisher
Wilkes M, Siva K, Chen J, Varetti G, Youn M, Chae H, et al. Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase. Nat Commun. 2020;11:3344 pubmed publisher
Patra D, Kim J, Zhang Q, Tycksen E, Sandell L. Site-1 protease ablation in the osterix-lineage in mice results in bone marrow neutrophilia and hematopoietic stem cell alterations. Biol Open. 2020;9: pubmed publisher
Jiang M, Ye J, Wang X, Li N, Wang Y, Shi Y. Phosphatase SHP1 impedes mesenchymal stromal cell immunosuppressive capacity modulated by JAK1/STAT3 and P38 signals. Cell Biosci. 2020;10:65 pubmed publisher
Kroeger C, Roesler R, Wiese S, Hainzl A, Gatzka M. Interaction of Deubiquitinase 2A-DUB/MYSM1 with DNA Repair and Replication Factors. Int J Mol Sci. 2020;21: pubmed publisher
Wei Q, Nakahara F, Asada N, Zhang D, Gao X, Xu C, et al. Snai2 Maintains Bone Marrow Niche Cells by Repressing Osteopontin Expression. Dev Cell. 2020;53:503-513.e5 pubmed publisher
Wang L, Fan J, Han L, Qi H, Wang Y, Wang H, et al. The micropeptide LEMP plays an evolutionarily conserved role in myogenesis. Cell Death Dis. 2020;11:357 pubmed publisher
Zheng Y, Wang N, Wang S, Yang B, Situ H, Zhong L, et al. XIAOPI formula inhibits the pre-metastatic niche formation in breast cancer via suppressing TAMs/CXCL1 signaling. Cell Commun Signal. 2020;18:48 pubmed publisher
Davis F, denDekker A, Kimball A, Joshi A, El Azzouny M, Wolf S, et al. Epigenetic Regulation of TLR4 in Diabetic Macrophages Modulates Immunometabolism and Wound Repair. J Immunol. 2020;204:2503-2513 pubmed publisher
Houri K, Mori T, Onodera Y, Tsujimoto T, Takehara T, Nakao S, et al. miR-142 induces accumulation of reactive oxygen species (ROS) by inhibiting pexophagy in aged bone marrow mesenchymal stem cells. Sci Rep. 2020;10:3735 pubmed publisher
Hou M, Han J, Li G, Kwon M, Jiang J, Emani S, et al. Multipotency of mouse trophoblast stem cells. Stem Cell Res Ther. 2020;11:55 pubmed publisher
Hidalgo San Jose L, Sunshine M, Dillingham C, Chua B, Krutá M, Hong Y, et al. Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal. Cell Rep. 2020;30:69-80.e6 pubmed publisher
Naipauer J, Rosario S, Gupta S, Premer C, Méndez Solís O, Schlesinger M, et al. PDGFRA defines the mesenchymal stem cell Kaposi's sarcoma progenitors by enabling KSHV oncogenesis in an angiogenic environment. PLoS Pathog. 2019;15:e1008221 pubmed publisher
Wang J, Wang D, Chu K, Li W, Zeng Y. Procr-expressing progenitor cells are responsible for murine ovulatory rupture repair of ovarian surface epithelium. Nat Commun. 2019;10:4966 pubmed publisher
Madaro L, Torcinaro A, De Bardi M, Contino F, Pelizzola M, Diaferia G, et al. Macrophages fine tune satellite cell fate in dystrophic skeletal muscle of mdx mice. PLoS Genet. 2019;15:e1008408 pubmed publisher
Onodera Y, Teramura T, Takehara T, Fukuda K. Transforming Growth Factor β-Activated Kinase 1 Regulates Mesenchymal Stem Cell Proliferation Through Stabilization of Yap1/Taz Proteins. Stem Cells. 2019;37:1595-1605 pubmed publisher
Morganti C, Bonora M, Ito K. Improving the Accuracy of Flow Cytometric Assessment of Mitochondrial Membrane Potential in Hematopoietic Stem and Progenitor Cells Through the Inhibition of Efflux Pumps. J Vis Exp. 2019;: pubmed publisher
Durham E, Howie R, Larson N, LaRue A, Cray J. Pharmacological exposures may precipitate craniosynostosis through targeted stem cell depletion. Stem Cell Res. 2019;40:101528 pubmed publisher
van de Vlekkert D, Demmers J, Nguyen X, Campos Y, Machado E, Annunziata I, et al. Excessive exosome release is the pathogenic pathway linking a lysosomal deficiency to generalized fibrosis. Sci Adv. 2019;5:eaav3270 pubmed publisher
Kobayashi H, Morikawa T, Okinaga A, Hamano F, Hashidate Yoshida T, Watanuki S, et al. Environmental Optimization Enables Maintenance of Quiescent Hematopoietic Stem Cells Ex Vivo. Cell Rep. 2019;28:145-158.e9 pubmed publisher
Huang J, Zhao L, Fan Y, Liao L, Ma P, Xiao G, et al. The microRNAs miR-204 and miR-211 maintain joint homeostasis and protect against osteoarthritis progression. Nat Commun. 2019;10:2876 pubmed publisher
Boonekamp K, Kretzschmar K, Wiener D, Asra P, Derakhshan S, Puschhof J, et al. Long-term expansion and differentiation of adult murine epidermal stem cells in 3D organoid cultures. Proc Natl Acad Sci U S A. 2019;: pubmed publisher
Li J, Ayoub A, Xiu Y, Yin X, Sanders J, Mesfin A, et al. TGFβ-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis. Nat Commun. 2019;10:2795 pubmed publisher
Lasso P, Llano Murcia M, Sandoval T, Urueña C, Barreto A, Fiorentino S. Breast Tumor Cells Highly Resistant to Drugs Are Controlled Only by the Immune Response Induced in an Immunocompetent Mouse Model. Integr Cancer Ther. 2019;18:1534735419848047 pubmed publisher
Xu W, Cherrier D, Chea S, Vosshenrich C, Serafini N, Petit M, et al. An Id2RFP-Reporter Mouse Redefines Innate Lymphoid Cell Precursor Potentials. Immunity. 2019;50:1054-1068.e3 pubmed publisher
Balzano M, De Grandis M, Vu Manh T, Chasson L, Bardin F, Farina A, et al. Nidogen-1 Contributes to the Interaction Network Involved in Pro-B Cell Retention in the Peri-sinusoidal Hematopoietic Stem Cell Niche. Cell Rep. 2019;26:3257-3271.e8 pubmed publisher
Moretti F, Klapproth S, Ruppert R, Margraf A, Weber J, Pick R, et al. Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus. elife. 2018;7: pubmed publisher
Schubert R, Sann J, Frueh J, Ullrich E, Geiger H, Baer P. Tracking of Adipose-Derived Mesenchymal Stromal/Stem Cells in a Model of Cisplatin-Induced Acute Kidney Injury: Comparison of Bioluminescence Imaging versus qRT-PCR. Int J Mol Sci. 2018;19: pubmed publisher
Bayindir Buchhalter I, Wolff G, Lerch S, Sijmonsma T, Schuster M, Gronych J, et al. Cited4 is a sex-biased mediator of the antidiabetic glitazone response in adipocyte progenitors. EMBO Mol Med. 2018;10: pubmed publisher
Lee D, Taniguchi N, Sato K, Choijookhuu N, Hishikawa Y, Kataoka H, et al. HMGB2 is a novel adipogenic factor that regulates ectopic fat infiltration in skeletal muscles. Sci Rep. 2018;8:9601 pubmed publisher
Xu C, Gao X, Wei Q, Nakahara F, Zimmerman S, Mar J, et al. Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow. Nat Commun. 2018;9:2449 pubmed publisher
Schmidt K, Zhang Q, Tasdogan A, Petzold A, Dahl A, Arneth B, et al. The H3K4 methyltransferase Setd1b is essential for hematopoietic stem and progenitor cell homeostasis in mice. elife. 2018;7: pubmed publisher
Ge J, Burnier L, Adamopoulou M, Kwa M, Schaks M, Rottner K, et al. RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells. J Biol Chem. 2018;293:9358-9369 pubmed publisher
Yamamoto R, Wilkinson A, Ooehara J, Lan X, Lai C, Nakauchi Y, et al. Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment. Cell Stem Cell. 2018;22:600-607.e4 pubmed publisher
Philippeos C, Telerman S, Oulès B, Pisco A, Shaw T, Elgueta R, et al. Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations. J Invest Dermatol. 2018;138:811-825 pubmed publisher
Reismann D, Stefanowski J, Gunther R, Rakhymzhan A, Matthys R, Nützi R, et al. Longitudinal intravital imaging of the femoral bone marrow reveals plasticity within marrow vasculature. Nat Commun. 2017;8:2153 pubmed publisher
Mehta C, Johnson K, Gao X, Ong I, Katsumura K, McIver S, et al. Integrating Enhancer Mechanisms to Establish a Hierarchical Blood Development Program. Cell Rep. 2017;20:2966-2979 pubmed publisher
Chaudhary J, Rath P. Microgrooved-surface topography enhances cellular division and proliferation of mouse bone marrow-derived mesenchymal stem cells. PLoS ONE. 2017;12:e0182128 pubmed publisher
Gao S, Zheng G, Wang L, Liang Y, Zhang S, Lao X, et al. Zoledronate suppressed angiogenesis and osteogenesis by inhibiting osteoclasts formation and secretion of PDGF-BB. PLoS ONE. 2017;12:e0179248 pubmed publisher
Ambrosi T, Scialdone A, Graja A, Gohlke S, Jank A, Bocian C, et al. Adipocyte Accumulation in the Bone Marrow during Obesity and Aging Impairs Stem Cell-Based Hematopoietic and Bone Regeneration. Cell Stem Cell. 2017;20:771-784.e6 pubmed publisher
Li H, Liu P, Xu S, Li Y, Dekker J, Li B, et al. FOXP1 controls mesenchymal stem cell commitment and senescence during skeletal aging. J Clin Invest. 2017;127:1241-1253 pubmed publisher
Géraud C, Koch P, Zierow J, Klapproth K, Busch K, Olsavszky V, et al. GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis. J Clin Invest. 2017;127:1099-1114 pubmed publisher
Cabañero D, Irie T, Celorrio M, Trousdale C, Owens D, Virley D, et al. Identification of an epidermal keratinocyte AMPA glutamate receptor involved in dermatopathies associated with sensory abnormalities. Pain Rep. 2016;1: pubmed publisher
Tao L, Xiang D, Xie Y, Bronson R, Li Z. Induced p53 loss in mouse luminal cells causes clonal expansion and development of mammary tumours. Nat Commun. 2017;8:14431 pubmed publisher
Shirai C, White B, Tripathi M, Tapia R, Ley J, Ndonwi M, et al. Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome. Nat Commun. 2017;8:14060 pubmed publisher
Ryu D, Lim J, Lee S, Park G, Min C. Induction of Indoleamine 2,3-dioxygenase by Pre-treatment with Poly(I:C) May Enhance the Efficacy of MSC Treatment in DSS-induced Colitis. Immune Netw. 2016;16:358-365 pubmed publisher
Hahm E, Wei C, Fernandez I, Li J, Tardi N, Tracy M, et al. Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease. Nat Med. 2017;23:100-106 pubmed publisher
Weng L, Hu X, Kumar B, García M, Todorov I, Jung X, et al. Identification of a CD133-CD55- population functions as a fetal common skeletal progenitor. Sci Rep. 2016;6:38632 pubmed publisher
Davies O, Grover L, Lewis M, Liu Y. PDGF is a potent initiator of bone formation in a tissue engineered model of pathological ossification. J Tissue Eng Regen Med. 2018;12:e355-e367 pubmed publisher
Damgaard R, Walker J, Marco Casanova P, Morgan N, Titheradge H, Elliott P, et al. The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity. Cell. 2016;166:1215-1230.e20 pubmed publisher
Mastrogiannaki M, Lichtenberger B, Reimer A, Collins C, Driskell R, Watt F. β-Catenin Stabilization in Skin Fibroblasts Causes Fibrotic Lesions by Preventing Adipocyte Differentiation of the Reticular Dermis. J Invest Dermatol. 2016;136:1130-1142 pubmed publisher
Pinto A, Ilinykh A, Ivey M, Kuwabara J, D Antoni M, Debuque R, et al. Revisiting Cardiac Cellular Composition. Circ Res. 2016;118:400-9 pubmed publisher
Johnson K, Kong G, Gao X, Chang Y, Hewitt K, Sanalkumar R, et al. Cis-regulatory mechanisms governing stem and progenitor cell transitions. Sci Adv. 2015;1:e1500503 pubmed publisher
Kraut B, Maier H, Kókai E, Fiedler K, Boettger T, Illing A, et al. Cardiac-Specific Activation of IKK2 Leads to Defects in Heart Development and Embryonic Lethality. PLoS ONE. 2015;10:e0141591 pubmed publisher
Hettmer S, Lin M, Tchessalova D, Tortorici S, Castiglioni A, Desai T, et al. Hedgehog-driven myogenic tumors recapitulate skeletal muscle cellular heterogeneity. Exp Cell Res. 2016;340:43-52 pubmed publisher
Tuorto F, Herbst F, Alerasool N, Bender S, Popp O, Federico G, et al. The tRNA methyltransferase Dnmt2 is required for accurate polypeptide synthesis during haematopoiesis. EMBO J. 2015;34:2350-62 pubmed publisher
Shankman L, Gomez D, Cherepanova O, Salmon M, Alencar G, Haskins R, et al. KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis. Nat Med. 2015;21:628-37 pubmed publisher
Vahdat S, Mousavi S, Omrani G, Gholampour M, Sotoodehnejadnematalahi F, Ghazizadeh Z, et al. Cellular and molecular characterization of human cardiac stem cells reveals key features essential for their function and safety. Stem Cells Dev. 2015;24:1390-404 pubmed publisher
Jeffery E, Church C, Holtrup B, Colman L, Rodeheffer M. Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity. Nat Cell Biol. 2015;17:376-85 pubmed publisher
Danielson L, Reavie L, Coussens M, Davalos V, Castillo Martin M, Guijarro M, et al. Limited miR-17-92 overexpression drives hematologic malignancies. Leuk Res. 2015;39:335-41 pubmed publisher
Samant M, Jackson C, Felix C, Jones A, Goodrich D, Foster B, et al. Multi-Drug Resistance ABC Transporter Inhibition Enhances Murine Ventral Prostate Stem/Progenitor Cell Differentiation. Stem Cells Dev. 2015;24:1236-51 pubmed publisher
Kimura Y, Komaki M, Iwasaki K, Sata M, Izumi Y, Morita I. Recruitment of bone marrow-derived cells to periodontal tissue defects. Front Cell Dev Biol. 2014;2:19 pubmed publisher
Boomsma R, Geenen D. Evidence for Transfer of Membranes from Mesenchymal Stem Cells to HL-1 Cardiac Cells. Stem Cells Int. 2014;2014:653734 pubmed publisher
Xia P, Wang S, Huang G, Zhu P, Li M, Ye B, et al. WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner. J Exp Med. 2014;211:2119-34 pubmed publisher
Xiao G, Liu I, Cheng C, Chang C, Lee Y, Cheng W, et al. Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy. PLoS ONE. 2014;9:e106538 pubmed publisher
Chu D, Mohammed Ali Z, Jiménez Saiz R, Walker T, Goncharova S, Llop Guevara A, et al. T helper cell IL-4 drives intestinal Th2 priming to oral peanut antigen, under the control of OX40L and independent of innate-like lymphocytes. Mucosal Immunol. 2014;7:1395-404 pubmed publisher
Donati G, Proserpio V, Lichtenberger B, Natsuga K, Sinclair R, Fujiwara H, et al. Epidermal Wnt/β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors. Proc Natl Acad Sci U S A. 2014;111:E1501-9 pubmed publisher
Furtado M, Costa M, Pranoto E, Salimova E, Pinto A, Lam N, et al. Cardiogenic genes expressed in cardiac fibroblasts contribute to heart development and repair. Circ Res. 2014;114:1422-34 pubmed publisher
Cheng C, Lee Y, Lin S, HuangFu W, Liu I. Cell-autonomous heparanase modulates self-renewal and migration in bone marrow-derived mesenchymal stem cells. J Biomed Sci. 2014;21:21 pubmed publisher
Wu T, Chou Y, Chiu P, Tang M, Hu C, Yeh M. Validation of the effects of TGF-?1 on tumor recurrence and prognosis through tumor retrieval and cell mechanical properties. Cancer Cell Int. 2014;14:20 pubmed publisher
Hong S, Alapure B, Lu Y, Tian H, Wang Q. Immunohistological localization of endogenous unlabeled stem cells in wounded skin. J Histochem Cytochem. 2014;62:276-85 pubmed publisher
Huang C, Tang M, Yehling E, Zhang X. Overexpressing sonic hedgehog peptide restores periosteal bone formation in a murine bone allograft transplantation model. Mol Ther. 2014;22:430-439 pubmed publisher
Carofino B, Ayanga B, Justice M. A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL). Dis Model Mech. 2013;6:1494-506 pubmed publisher
Park S, Wamsley H, Bae K, Hu Z, Li X, Choe S, et al. Conditional deletion of Jak2 reveals an essential role in hematopoiesis throughout mouse ontogeny: implications for Jak2 inhibition in humans. PLoS ONE. 2013;8:e59675 pubmed publisher
Johnson K, Hsu A, Ryu M, Wang J, Gao X, Boyer M, et al. Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity. J Clin Invest. 2012;122:3692-704 pubmed publisher
Grajales L, García J, Geenen D. Induction of cardiac myogenic lineage development differs between mesenchymal and satellite cells and is accelerated by bone morphogenetic protein-4. J Mol Cell Cardiol. 2012;53:382-91 pubmed publisher
Xu K, Usary J, Kousis P, Prat A, Wang D, Adams J, et al. Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer. Cancer Cell. 2012;21:626-41 pubmed publisher
Satpathy A, Kc W, Albring J, Edelson B, Kretzer N, Bhattacharya D, et al. Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages. J Exp Med. 2012;209:1135-52 pubmed publisher
Gu P, Min J, Wang Y, Huang C, Peng T, Chai W, et al. CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion. EMBO J. 2012;31:2309-21 pubmed publisher
Klimmeck D, Hansson J, Raffel S, Vakhrushev S, Trumpp A, Krijgsveld J. Proteomic cornerstones of hematopoietic stem cell differentiation: distinct signatures of multipotent progenitors and myeloid committed cells. Mol Cell Proteomics. 2012;11:286-302 pubmed publisher
Purtha W, Swiecki M, Colonna M, Diamond M, Bhattacharya D. Spontaneous mutation of the Dock2 gene in Irf5-/- mice complicates interpretation of type I interferon production and antibody responses. Proc Natl Acad Sci U S A. 2012;109:E898-904 pubmed publisher
Hu T, Ghazaryan S, Sy C, Wiedmeyer C, Chang V, Wu L. Concomitant inactivation of Rb and E2f8 in hematopoietic stem cells synergizes to induce severe anemia. Blood. 2012;119:4532-42 pubmed publisher
Yan A, Avraham T, Zampell J, Haviv Y, Weitman E, Mehrara B. Adipose-derived stem cells promote lymphangiogenesis in response to VEGF-C stimulation or TGF-?1 inhibition. Future Oncol. 2011;7:1457-73 pubmed publisher
Wang Y, Shen M, Chang S. Essential roles for Pot1b in HSC self-renewal and survival. Blood. 2011;118:6068-77 pubmed publisher
Chang Y, Kim H, Albacker L, Baumgarth N, McKenzie A, Smith D, et al. Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity. Nat Immunol. 2011;12:631-8 pubmed publisher
Heinonen K, Vanegas J, Lew D, Krosl J, Perreault C. Wnt4 enhances murine hematopoietic progenitor cell expansion through a planar cell polarity-like pathway. PLoS ONE. 2011;6:e19279 pubmed publisher
Bhullar J, Sollars V. YBX1 expression and function in early hematopoiesis and leukemic cells. Immunogenetics. 2011;63:337-50 pubmed publisher
Qiu Q, Hernandez J, Dean A, Rao P, Darlington G. CD24-positive cells from normal adult mouse liver are hepatocyte progenitor cells. Stem Cells Dev. 2011;20:2177-88 pubmed publisher
Varney M, Buchanan J, Dementieva Y, Hardman W, Sollars V. A high omega-3 fatty acid diet has different effects on early and late stage myeloid progenitors. Lipids. 2011;46:47-57 pubmed publisher
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product information
Product Type :
Antibody
Product Name :
Ly-6A/E (Sca-1) Monoclonal Antibody (D7), Alexa Fluor 700, eBioscience
Catalog # :
56-5981-82
Quantity :
100 ug
Price :
US 381.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.5 ug/test
Species :
Mouse
Clone :
D7
Isotype :
IgG2a, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
Stem Cell Antigen-1 (Sca-1) is a member of the lymphocyte antigen 6 (Ly-6) family. It is expressed on multipotent hematopoietic stem cells (HSC) and is used as a marker of HSC in mice. Sca-1 is used in combination with lineage depletion antibodies to identify murine HSC. Sca-1 can be found in fetal liver, adult bone marrow, and adult peripheral blood and spleen. Sca-1 may be involved in the regulation of B and T cell activation.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 ug/test
Aliases :
9804; locus A/E; Locus AE; Ly6; Ly67; Ly6a; Ly-6A.2; Ly-6A.2/Ly-6E.1; Ly6A/E; Ly-6A/E; ly6a-e; Ly6e; Ly-6E; Ly-6E.1; lymphocyte antigen 6 complex; lymphocyte antigen 6 complex, locus A; lymphocyte antigen 6 complex, locus E; lymphocyte antigen 6A-2/6E-1; Lymphocyte antigen 6E; RIG-E; Sca1; Sca-1; Sca-2; stem cell antigen 1; Stem cell antigen 2; TAP; T-cell-activating protein; thymic shared antigen 1; Tsa1; TSA-1
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA