CD304 (Neuropilin-1) Monoclonal Antibody (TNKUSOHA), Alexa Fluor 700, eBioscience | Invitrogen 56-3049-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD304 (Neuropilin-1) Monoclonal Antibody (TNKUSOHA), Alexa Fluor 700, eBioscience

catalog :

56-3049-42

quantity :

100 Tests

price :

US 447.00

clonality :

monoclonal

host :

mouse

conjugate :

AF700

clone name :

TNKUSOHA

reactivity :

human

application :

flow cytometry

citations: 4

Reference
Solly F, Angelot F, Garand R, Ferrand C, Seilles E, Schillinger F, et al. CD304 is preferentially expressed on a subset of B-lineage acute lymphoblastic leukemia and represents a novel marker for minimal residual disease detection by flow cytometry. Cytometry A. 2012;81:17-24 pubmed publisher
Mittag D, Proietto A, Loudovaris T, Mannering S, Vremec D, Shortman K, et al. Human dendritic cell subsets from spleen and blood are similar in phenotype and function but modified by donor health status. J Immunol. 2011;186:6207-17 pubmed publisher
Kassianos A, Jongbloed S, Hart D, Radford K. Isolation of human blood DC subtypes. Methods Mol Biol. 2010;595:45-54 pubmed publisher
Sarris M, Andersen K, Randow F, Mayr L, Betz A. Neuropilin-1 expression on regulatory T cells enhances their interactions with dendritic cells during antigen recognition. Immunity. 2008;28:402-13 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD304 (Neuropilin-1) Monoclonal Antibody (TNKUSOHA), Alexa Fluor 700, eBioscience

Catalog # :

56-3049-42

Quantity :

100 Tests

Price :

US 447.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (0.125 ug)/test

Species :

Human

Clone :

TNKUSOHA

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

Neuropilin 1 is a 923 amino acid containing membrane bound coreceptor to a tyrosine kinase receptor belonging to the neuropilin family with two CUB domains, two F5/8 type C domains and a MAM domain. Neuropilin 1 forms a heterodimer with NRP2 (Neuropilin 2) and is known to bind to plexin (PLXNB1) to form semaphorin receptors. Expressed mostly in the nervous system this receptor is implicated in a wide range of functions including in the development of the cardiovascular system, angiogenesis, repulsive axon guidance, formation of certain neuronal circuits, cell survival, control of neuronal migration and organogenesis outside the nervous system. This semaphorin receptor functions as receptors for both the semaphorins and vascular endothelial growth factor and is also a regulator of VEGF-induced angiogenesis. Neuropilin 1 may be involved in aggressive advanced prostate carcinoma and in the progression of breast cancer.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.125 ug)/test

Aliases :

A5 protein; BDCA4; C530029I03; CD304; Neuropilin; neuropilin 1; Neuropilin1; neuropilin-1; Neuropilin-1 precursor (A5 protein); NP1; NP-1; Npn1; NPN-1; NRP; NRP 1; Nrp1; sNRP 1; sNRP1; soluble NRP 1; soluble NRP1; transmembrane receptor; vascular endothelial cell growth factor 165 receptor; VEGF165R