product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD7 Monoclonal Antibody (eBio124-1D1 (124-1D1)), Alexa Fluor 700, eBioscience™
catalog :
56-0079-42
quantity :
100 Tests
price :
292 USD
clonality :
monoclonal
host :
mouse
conjugate :
AF700
clone name :
eBio124-1D1 (124-1D1)
reactivity :
human
application :
flow cytometry
more info or order :
Invitrogen product webpage
citations: 7
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig s1
Voigt J, Malone D, Dias J, Leeansyah E, Björkström N, Ljunggren H, et al. Proteome analysis of human CD56neg NK cells reveals a homogeneous phenotype surprisingly similar to CD56dim NK cells. Eur J Immunol. 2018;48:1456-1469 pubmed publisher
Fali T, Fabre Mersseman V, Yamamoto T, Bayard C, Papagno L, Fastenackels S, et al. Elderly human hematopoietic progenitor cells express cellular senescence markers and are more susceptible to pyroptosis. JCI Insight. 2018;3: pubmed publisher
Li Y, Brauer P, Singh J, Xhiku S, Yoganathan K, Zuniga Pflucker J, et al. Targeted Disruption of TCF12 Reveals HEB as Essential in Human Mesodermal Specification and Hematopoiesis. Stem Cell Reports. 2017;9:779-795 pubmed publisher
York V, Milush J. Ex vivo Human Natural Killer (NK) Cell Stimulation and Intracellular IFN? and CD107a Cytokine Staining. Bio Protoc. 2015;5: pubmed
Lyman S, Escobar S, Rousseau A, Armstrong A, Fanslow W. Identification of CD7 as a cognate of the human K12 (SECTM1) protein. J Biol Chem. 2000;275:3431-7 pubmed
Sato A, Balamuth F, Ugen K, Williams W, Weiner D. Identification of CD7 glycoprotein as an accessory molecule in HIV-1-mediated syncytium formation and cellfree infection. J Immunol. 1994;152:5142-52 pubmed
Aruffo A, Seed B. Molecular cloning of two CD7 (T-cell leukemia antigen) cDNAs by a COS cell expression system. EMBO J. 1987;6:3313-6 pubmed
product information
Product Type :
Antibody
Product Name :
CD7 Monoclonal Antibody (eBio124-1D1 (124-1D1)), Alexa Fluor 700, eBioscience™
Catalog # :
56-0079-42
Quantity :
100 Tests
Price :
292 USD
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 5 µL (0.5 µg)/test
Species :
Human
Clone :
eBio124-1D1 (124-1D1)
Isotype :
IgG1, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
CD7 (gp40, Leu9) is a 40 kDa member of the immunoglobulin gene superfamily. CD7 contains N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxy-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. Further, CD7 is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation. Expression of CD7 is an important marker used in leukemia diagnostics.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 µL (0.5 µg)/test
Aliases :
Cd7; CD7 antigen; CD7 antigen (p41); Cd7 molecule; GP40; LEU-9; p41 protein; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen Leu-9; Tp40; TP41
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA