Snail1 Monoclonal Antibody (20C8), Alexa Fluor 488, eBioscience | Invitrogen 53-9859-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Snail1 Monoclonal Antibody (20C8), Alexa Fluor 488, eBioscience

catalog :

53-9859-82

quantity :

100 ug

price :

US 471.00

clonality :

monoclonal

host :

mouse

conjugate :

AF488

clone name :

20C8

The same clone is also sold as:

Novus Biologicals: NBP2-50300

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 8

Reference
Mitra D, Saha D, Das G, Mukherjee R, Banerjee S, Alam N, et al. Lupeol synergizes with 5-fluorouracil to combat c-MET/EphA2 mediated chemoresistance in triple negative breast cancer. iScience. 2023;26:108395 pubmed publisher
Daley R, Maddipatla V, Ghosh S, Chowdhury O, Hose S, Zigler J, et al. Aberrant Akt2 signaling in the RPE may contribute to retinal fibrosis process in diabetic retinopathy. Cell Death Discov. 2023;9:243 pubmed publisher
Guo F, Ma J, Li C, Liu S, Wu W, Li C, et al. PRR15 deficiency facilitates malignant progression by mediating PI3K/Akt signaling and predicts clinical prognosis in triple-negative rather than non-triple-negative breast cancer. Cell Death Dis. 2023;14:272 pubmed publisher
Fan M, Yang K, Wang X, Chen L, Gill P, Ha T, et al. Lactate promotes endothelial-to-mesenchymal transition via Snail1 lactylation after myocardial infarction. Sci Adv. 2023;9:eadc9465 pubmed publisher
He Z, Lei S, Liang F, Tan L, Zhang W, Xie L, et al. Low-Dose Albendazole Inhibits Epithelial-Mesenchymal Transition of Melanoma Cells by Enhancing Phosphorylated GSK-3β/Tyr216 Accumulation. J Oncol. 2021;2021:4475192 pubmed publisher
Fu S, Lai M, Zheng Y, Sun Y, Qiu J, Gui F, et al. MiR-195 inhibits the ubiquitination and degradation of YY1 by Smurf2, and induces EMT and cell permeability of retinal pigment epithelial cells. Cell Death Dis. 2021;12:708 pubmed publisher
Guo X, Zhu R, Luo A, Zhou H, Ding F, Yang H, et al. EIF3H promotes aggressiveness of esophageal squamous cell carcinoma by modulating Snail stability. J Exp Clin Cancer Res. 2020;39:175 pubmed publisher
Dai B, Yang Z, Deng P, Chen Y, He Z, Yang X, et al. HOXC10 promotes migration and invasion via the WNT-EMT signaling pathway in oral squamous cell carcinoma. J Cancer. 2019;10:4540-4551 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Snail1 Monoclonal Antibody (20C8), Alexa Fluor 488, eBioscience

Catalog # :

53-9859-82

Quantity :

100 ug

Price :

US 471.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-Dependent, Flow Cytometry: Assay-Dependent, Immunocytochemistry: 20 ug/mL, Immunohistochemistry (Paraffin): 20 ug/mL, Western Blot: Assay-Dependent

Species :

Human

Clone :

20C8

Isotype :

IgG2a, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

Zinc finger protein SNAI1 (SNAIL)is a zinc finger transcriptional repressor which down regulates the expression of the ectodermal gene within the mesoderm and functions to form the mesoderm and neural crest. It is reported that SNAI1 acts as an important factor of tumor invasion as evidenced by its role in E-cadherin down-regulation and induction of epithelial-mesenchymal transition (EMT). In human breast cancer, the expression of SNAI1 and/or the homologous SNAI2 (Slug) has been associated with E-cadherin repression, local or distant metastasis, tumor recurrence, or poor prognosis in different tumor series. It is also reported that Snail 1 protein in the stromamay be anew putative prognosis marker for colon tumors.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-Dependent, Flow Cytometry: Assay-Dependent, Immunocytochemistry: 20 ug/mL, Immunohistochemistry (Paraffin): 20 ug/mL, Western Blot: Assay-Dependent

Aliases :

AI194338; dJ710H13.1; Protein sna; protein snail homolog 1; SLUGH2; SNA; Sna protein; Sna1; SNAH; snai; SNAI1; Snail; snail 1; snail 1 homolog; snail 1 zinc finger protein; snail 1, zinc finger protein; snail family transcriptional repressor 1; snail family zinc finger 1; snail homolog 1; Snail1; Zinc finger protein SNAI1