Nestin Monoclonal Antibody (10C2), Alexa Fluor™ 488, eBioscience | Invitrogen 53-9843-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Nestin Monoclonal Antibody (10C2), Alexa Fluor™ 488, eBioscience

catalog :

53-9843-82

quantity :

100 µg

price :

US 430.00

clonality :

monoclonal

host :

mouse

conjugate :

AF488

clone name :

10C2

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, flow cytometry

more info or order :

Invitrogen product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig s3	Okumura T, Horie Y, Lai C, Lin H, Shoda H, Natsumoto B, et al. Robust and highly efficient hiPSC generation from patient non-mobilized peripheral blood-derived CD34+ cells using the auto-erasable Sendai virus vector. Stem Cell Res Ther. 2019;10:185 pubmed publisher
	Christopher G, Noort R, Esseltine J. Connexin 43 Gene Ablation Does Not Alter Human Pluripotent Stem Cell Germ Lineage Specification. Biomolecules. 2021;12: pubmed publisher
	Otto L, Rahn S, Daunke T, Walter F, Winter E, M xf6 ller J, et al. Initiation of Pancreatic Cancer: The Interplay of Hyperglycemia and Macrophages Promotes the Acquisition of Malignancy-Associated Properties in Pancreatic Ductal Epithelial Cells. Int J Mol Sci. 2021;22: pubmed publisher
	Noort R, Christopher G, Esseltine J. Pannexin 1 Influences Lineage Specification of Human iPSCs. Front Cell Dev Biol. 2021;9:659397 pubmed publisher
	Qiao H, Guo M, Shang J, Zhao W, Wang Z, Liu N, et al. Herpes simplex virus type 1 infection leads to neurodevelopmental disorder-associated neuropathological changes. PLoS Pathog. 2020;16:e1008899 pubmed publisher
	Siney E, Holden A, Casselden E, Bulstrode H, Thomas G, Willaime Morawek S. Metalloproteinases ADAM10 and ADAM17 Mediate Migration and Differentiation in Glioblastoma Sphere-Forming Cells. Mol Neurobiol. 2017;54:3893-3905 pubmed publisher
	Bhanu N, Sidoli S, Garcia B. Histone modification profiling reveals differential signatures associated with human embryonic stem cell self-renewal and differentiation. Proteomics. 2016;16:448-58 pubmed publisher
	Abe S, Yamaguchi S, Sato Y, Harada K. Sphere-Derived Multipotent Progenitor Cells Obtained From Human Oral Mucosa Are Enriched in Neural Crest Cells. Stem Cells Transl Med. 2016;5:117-28 pubmed publisher
	Mullins C, Schneider B, Stockhammer F, Krohn M, Classen C, Linnebacher M. Establishment and characterization of primary glioblastoma cell lines from fresh and frozen material: a detailed comparison. PLoS ONE. 2013;8:e71070 pubmed publisher
	Buck J, Garde S, Kohl C, Knaup Gregori P. Towards a comprehensive electronic patient record to support an innovative individual care concept for premature infants using the openEHR approach. Int J Med Inform. 2009;78:521-31 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Nestin Monoclonal Antibody (10C2), Alexa Fluor™ 488, eBioscience

Catalog # :

53-9843-82

Quantity :

100 µg

Price :

US 430.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: Assay-Dependent, Immunocytochemistry: 10 µg/mL, Immunohistochemistry: Assay-Dependent

Species :

Human

Clone :

10C2

Isotype :

IgG1

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

Nestin is a Class VI intermediate filament abundantly produced in the developing central nervous system (CNS) and in early embryonic neuroepithelial stem cells. Nestin has been widely used as a predominant marker for stem/progenitor cells, glioma cells, and tumor endothelial cells. Also, Nestin is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumors. Highly specific antibodies to human Nestin can aid in characterizing progenitor cells differentiating into distinct lineages, in enhancing the therapeutic potential of human neural stem/progenitor cells in the treatment of CNS diseases or injury, and in identifying neuroepithelial tumor cells. Nestin expression has been observed in pancreatic hematopoietic stem cell populations, and is considered a novel angiogenesis marker of proliferating endothelial cells in colorectal cancer tissue.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-Dependent, Immunocytochemistry: 10 µg/mL, Immunohistochemistry: Assay-Dependent

Aliases :

AA166324; C78523; ESTM46; FLJ21841; intermediate filament protein; Nbla00170; Nes; Nestin

more info or order :

Invitrogen product webpage