PLZF Monoclonal Antibody (Mags.21F7), Alexa Fluor™ 488, eBioscience | Invitrogen 53-9320-80 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PLZF Monoclonal Antibody (Mags.21F7), Alexa Fluor™ 488, eBioscience

catalog :

53-9320-80

quantity :

25 µg

price :

US 165.00

clonality :

monoclonal

host :

mouse

conjugate :

AF488

clone name :

Mags.21F7

reactivity :

human, mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 18

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; 1:100; fig 3b	Alpaugh W, Voigt A, Dardari R, Su L, Al Khatib I, Shin W, et al. Loss of Ubiquitin Carboxy-Terminal Hydrolase L1 Impairs Long-Term Differentiation Competence and Metabolic Regulation in Murine Spermatogonial Stem Cells. Cells. 2021;10: pubmed publisher
	Kumar A, Yarosz E, Andren A, Zhang L, Lyssiotis C, Chang C. NKT cells adopt a glutamine-addicted phenotype to regulate their homeostasis and function. Cell Rep. 2022;41:111516 pubmed publisher
	Harsha Krovi S, Zhang J, Michaels Foster M, Brunetti T, Loh L, Scott Browne J, et al. Thymic iNKT single cell analyses unmask the common developmental program of mouse innate T cells. Nat Commun. 2020;11:6238 pubmed publisher
	Lei J, Yan W, Luo C, Guo Y, Zhang Y, Wang X, et al. Cytotoxicity of nonylphenol on spermatogonial stem cells via phosphatidylinositol-3-kinase/protein kinase B/mammalian target of rapamycin pathway. World J Stem Cells. 2020;12:500-513 pubmed publisher
	LUCAS B, White A, Cosway E, Parnell S, James K, Jones N, et al. Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells. Nat Commun. 2020;11:2198 pubmed publisher
	Clancy Thompson E, Chen G, LaMarche N, Ali L, Jeong H, Crowley S, et al. Transnuclear mice reveal Peyer's patch iNKT cells that regulate B-cell class switching to IgG1. EMBO J. 2019;38:e101260 pubmed publisher
	Pyaram K, Kumar A, Kim Y, Noel S, Reddy S, Rabb H, et al. Keap1-Nrf2 System Plays an Important Role in Invariant Natural Killer T Cell Development and Homeostasis. Cell Rep. 2019;27:699-707.e4 pubmed publisher
	Govindarajan S, Gaublomme D, Van der Cruyssen R, Verheugen E, Van Gassen S, Saeys Y, et al. Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine kinase IRE1alpha. Nat Commun. 2018;9:5340 pubmed publisher
	Eslahi N, Shakeri Zadeh A, Ashtari K, Pirhajati Mahabadi V, Tohidi Moghadam T, Shabani R, et al. In Vitro Cytotoxicity of Folate-Silica-Gold Nanorods on Mouse Acute Lymphoblastic Leukemia and Spermatogonial Cells. Cell J. 2019;21:14-26 pubmed publisher
	Clancy Thompson E, Chen G, Tyler P, Servos M, Barisa M, Brennan P, et al. Monoclonal Invariant NKT (iNKT) Cell Mice Reveal a Role for Both Tissue of Origin and the TCR in Development of iNKT Functional Subsets. J Immunol. 2017;199:159-171 pubmed publisher
	Hobbs R, La H, MÃ¤kelÃ¤ J, Kobayashi T, Noda T, Pandolfi P. Distinct germline progenitor subsets defined through Tsc2-mTORC1 signaling. EMBO Rep. 2015;16:467-80 pubmed publisher
	Lee Y, Holzapfel K, Zhu J, Jameson S, Hogquist K. Steady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells. Nat Immunol. 2013;14:1146-54 pubmed publisher
	Eidson M, Wahlstrom J, Beaulieu A, Zaidi B, Carsons S, Crow P, et al. Altered development of NKT cells, ?? T cells, CD8 T cells and NK cells in a PLZF deficient patient. PLoS ONE. 2011;6:e24441 pubmed publisher
	Kovalovsky D, ALONZO E, Uche O, Eidson M, Nichols K, Sant Angelo D. PLZF induces the spontaneous acquisition of memory/effector functions in T cells independently of NKT cell-related signals. J Immunol. 2010;184:6746-55 pubmed publisher
	ALONZO E, Gottschalk R, Das J, Egawa T, Hobbs R, Pandolfi P, et al. Development of promyelocytic zinc finger and ThPOK-expressing innate gamma delta T cells is controlled by strength of TCR signaling and Id3. J Immunol. 2010;184:1268-79 pubmed publisher
	Lee Y, Jeon Y, Kang B, Chung D, Park C, Shin H, et al. Generation of PLZF+ CD4+ T cells via MHC class II-dependent thymocyte-thymocyte interaction is a physiological process in humans. J Exp Med. 2010;207:237-46 pubmed publisher
	Savage A, Constantinides M, Han J, Picard D, Martin E, Li B, et al. The transcription factor PLZF directs the effector program of the NKT cell lineage. Immunity. 2008;29:391-403 pubmed publisher
	Martin P, Delmotte M, Formstecher P, Lefebvre P. PLZF is a negative regulator of retinoic acid receptor transcriptional activity. Nucl Recept. 2003;1:6 pubmed

product information

Product Type :

Antibody

Product Name :

PLZF Monoclonal Antibody (Mags.21F7), Alexa Fluor™ 488, eBioscience

Catalog # :

53-9320-80

Quantity :

25 µg

Price :

US 165.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Flow Cytometry: 1 µg/test

Species :

Human, Mouse

Clone :

Mags.21F7

Isotype :

IgG1, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 µg/test

Aliases :

AI467657; Green's luxoid; lu; luxoid; Lx; PLZF; Polydactyly-luxate syndrome; promyelocytic leukaemia zinc finger; promyelocytic leukemia zinc finger; Promyelocytic leukemia zinc finger protein; ZBTB16; Zfp145; zinc finger and BTB domain containing 16; zinc finger and BTB domain containing 16 protein; zinc finger and BTB domain-containing protein 16; Zinc finger protein 145; zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia); zinc finger protein PLZF; ZNF145

more info or order :

Invitrogen product webpage