CD205 Monoclonal Antibody (205yekta), Alexa Fluor 488, eBioscience | Invitrogen 53-2051-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD205 Monoclonal Antibody (205yekta), Alexa Fluor 488, eBioscience

catalog :

53-2051-82

quantity :

100 ug

price :

US 349.00

clonality :

monoclonal

host :

rat

conjugate :

AF488

clone name :

205yekta

reactivity :

mouse

application :

flow cytometry

citations: 12

Reference
Lee A, Scott M, Wimmers F, Arunachalam P, Luo W, Fox C, et al. A molecular atlas of innate immunity to adjuvanted and live attenuated vaccines, in mice. Nat Commun. 2022;13:549 pubmed publisher
LUCAS B, White A, Parnell S, Henley P, Jenkinson W, Anderson G. Progressive Changes in CXCR4 Expression That Define Thymocyte Positive Selection Are Dispensable For Both Innate and Conventional αβT-cell Development. Sci Rep. 2017;7:5068 pubmed publisher
Lee S, Carrero J, Uppaluri R, White J, Archambault J, Lai K, et al. Identifying the initiating events of anti-Listeria responses using mice with conditional loss of IFN-? receptor subunit 1 (IFNGR1). J Immunol. 2013;191:4223-34 pubmed publisher
Baik S, Jenkinson E, Lane P, Anderson G, Jenkinson W. Generation of both cortical and Aire(+) medullary thymic epithelial compartments from CD205(+) progenitors. Eur J Immunol. 2013;43:589-94 pubmed publisher
Fuertes Marraco S, Grosjean F, Duval A, Rosa M, Lavanchy C, Ashok D, et al. Novel murine dendritic cell lines: a powerful auxiliary tool for dendritic cell research. Front Immunol. 2012;3:331 pubmed publisher
Park C, Rodriguez A, Steinman R. PE-Cy5.5 conjugates bind to the cells expressing mouse DEC205/CD205. J Immunol Methods. 2012;384:184-90 pubmed publisher
Kar U, Srivastava M, Andersson A, Baratelli F, Huang M, Kickhoefer V, et al. Novel CCL21-vault nanocapsule intratumoral delivery inhibits lung cancer growth. PLoS ONE. 2011;6:e18758 pubmed publisher
Ch en I, Tsau J, Molkentin J, Komatsu M, Hedrick S. Mechanisms of necroptosis in T cells. J Exp Med. 2011;208:633-41 pubmed publisher
Bonifaz L, Bonnyay D, Charalambous A, Darguste D, Fujii S, Soares H, et al. In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination. J Exp Med. 2004;199:815-24 pubmed
Witmer Pack M, Swiggard W, Mirza A, Inaba K, Steinman R. Tissue distribution of the DEC-205 protein that is detected by the monoclonal antibody NLDC-145. II. Expression in situ in lymphoid and nonlymphoid tissues. Cell Immunol. 1995;163:157-62 pubmed
Inaba K, Swiggard W, Inaba M, Meltzer J, Mirza A, Sasagawa T, et al. Tissue distribution of the DEC-205 protein that is detected by the monoclonal antibody NLDC-145. I. Expression on dendritic cells and other subsets of mouse leukocytes. Cell Immunol. 1995;163:148-56 pubmed
Swiggard W, Mirza A, Nussenzweig M, Steinman R. DEC-205, a 205-kDa protein abundant on mouse dendritic cells and thymic epithelium that is detected by the monoclonal antibody NLDC-145: purification, characterization, and N-terminal amino acid sequence. Cell Immunol. 1995;165:302-11 pubmed

product information

Product Type :

Antibody

Product Name :

CD205 Monoclonal Antibody (205yekta), Alexa Fluor 488, eBioscience

Catalog # :

53-2051-82

Quantity :

100 ug

Price :

US 349.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.25 ug/test

Species :

Mouse

Clone :

205yekta

Isotype :

IgG2a, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region. Further, CD205 also prompts the reduced proliferation of B lymphocytes. Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 ug/test

Aliases :

CA-IX; CD205; CLEC13B; C-type lectin domain family 13 member B; DCL-1 fusion; DEC205; DEC-205; DEC-205/CD205 protein; gp200; gp200-MR6; group VI C-type animal lectin; LY75; ly-75; Lymphocyte antigen 75; membrane antigen MN; P54/58N; pMW1; RGD1565962; RP23-10L17.4