GFAP Monoclonal Antibody (2.2B10), Alexa Fluor 647, eBioscience | Invitrogen 51-9792-82 product information

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product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GFAP Monoclonal Antibody (2.2B10), Alexa Fluor 647, eBioscience

catalog :

51-9792-82

quantity :

100 ug

price :

US 436.00

clonality :

monoclonal

host :

rat

conjugate :

AF647

clone name :

2.2B10

reactivity :

human, mouse, rat, bovine

application :

immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

citations: 4

Reference
Glaubitz J, Wilden A, Golchert J, Homuth G, V xf6 lker U, Br xf6 ker B, et al. In mouse chronic pancreatitis CD25+FOXP3+ regulatory T cells control pancreatic fibrosis by suppression of the type 2 immune response. Nat Commun. 2022;13:4502 pubmed publisher
Takahashi F, Zhang C, Hohjoh H, Raveney B, Yamamura T, Hayashi N, et al. Immune-mediated neurodegenerative trait provoked by multimodal derepression of long-interspersed nuclear element-1. iScience. 2022;25:104278 pubmed publisher
Bessières B, Cruz E, Alberini C. Metabolomic profiling reveals a differential role for hippocampal glutathione reductase in infantile memory formation. elife. 2021;10: pubmed publisher
Granatiero V, Sayles N, Savino A, Konràd C, Kharas M, Kawamata H, et al. Modulation of the IGF1R-MTOR pathway attenuates motor neuron toxicity of human ALS SOD1G93A astrocytes. Autophagy. 2021;17:4029-4042 pubmed publisher

product information

Product Type :

Antibody

Product Name :

GFAP Monoclonal Antibody (2.2B10), Alexa Fluor 647, eBioscience

Catalog # :

51-9792-82

Quantity :

100 ug

Price :

US 436.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Bovine, Human, Mouse, Rat

Applications :

Flow Cytometry: 0.5 ug/test, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): Assay-dependent

Species :

Bovine, Human, Mouse, Rat

Clone :

2.2B10

Isotype :

IgG2a, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

GFAP (Glial fibrillary acidic protein) is a member of the class III intermediate filament protein family. GFAP is heavily and specifically expressed in astrocytes and certain astroglia of the central nervous system, in satellite cells of peripheral ganglia, and in non-myelinating Schwann cells of peripheral nerves. In addition, neural stem cells strongly express GFAP. Antibodies to GFAP are very useful as markers of astrocytic cells. In addition, many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. GFAP is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing of the GFAP gene results in multiple transcript variants encoding distinct isoforms.

Immunogen :

Enriched bovine glial filaments

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 ug/test, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): Assay-dependent

Aliases :

6330404F12Rik; 65 kDa glutamic acid decarboxylase; AI836096; ALXDRD; Astrocyte or Intermediate Filament Protein; cb345; class III intermediate filament protein; etID36982.3; FLJ45472; GAD(65); Gad2; Gad-2; GAD65; GAD-65; GFAP; GFAP epsilon; gfap protein; gfapl; glial fibrillary acidic protein; Glial Fibrillary Acidic Protein (GFAP); glial fibrillary acidic protein alpha; glutamate decarboxylase 2; Glutamate decarboxylase 65 kDa isoform; glutamic acid decarboxylase 2; I79_011607; intermediate filament; intermediate filament protein; intermediate filament protein; GFAP; Unknown (protein for MGC:139638); wu:fb34h11; wu:fk42c12; xx:af506734; zgc:110485; zGFAP; intermediate filament protein; zrf-1 antigen