Connexin 36 Polyclonal Antibody | Invitrogen 51-6300 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Connexin 36 Polyclonal Antibody

catalog :

51-6300

quantity :

100 µg

price :

US 375.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunoprecipitation, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:500; fig s8 western blot; mouse; 1:250; fig 6	Yao X, Wang M, He X, He F, Zhang S, Lu W, et al. Electrical coupling regulates layer 1 interneuron microcircuit formation in the neocortex. Nat Commun. 2016;7:12229 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:500	Bolte P, Herrling R, Dorgau B, Schultz K, Feigenspan A, Weiler R, et al. Expression and Localization of Connexins in the Outer Retina of the Mouse. J Mol Neurosci. 2016;58:178-92 pubmed publisher
	Lynn B, Li X, Hormuzdi S, Griffiths E, McGlade C, Nagy J. E3 ubiquitin ligases LNX1 and LNX2 localize at neuronal gap junctions formed by connexin36 in rodent brain and molecularly interact with connexin36. Eur J Neurosci. 2018;48:3062-3081 pubmed publisher
	Li J, Zhang S, Liu X, Han D, Xu J, Ma Y. Neuroprotective effects of leonurine against oxygen-glucose deprivation by targeting Cx36/CaMKII in PC12 cells. PLoS ONE. 2018;13:e0200705 pubmed publisher
	Tetenborg S, Yadav S, Hormuzdi S, Monyer H, Janssen Bienhold U, Dedek K. Differential Distribution of Retinal Ca2+/Calmodulin-Dependent Kinase II (CaMKII) Isoforms Indicates CaMKII-β and -δ as Specific Elements of Electrical Synapses Made of Connexin36 (Cx36). Front Mol Neurosci. 2017;10:425 pubmed publisher
	Liu L, Li C, Lu Y, Zong X, Luo C, Sun J, et al. Baclofen mediates neuroprotection on hippocampal CA1 pyramidal cells through the regulation of autophagy under chronic cerebral hypoperfusion. Sci Rep. 2015;5:14474 pubmed publisher
	Rubio M, Nagy J. Connexin36 expression in major centers of the auditory system in the CNS of mouse and rat: Evidence for neurons forming purely electrical synapses and morphologically mixed synapses. Neuroscience. 2015;303:604-29 pubmed publisher
	Fontes J, Ramsey J, Polk J, Koop A, Denisova J, Belousov A. Death of Neurons following Injury Requires Conductive Neuronal Gap Junction Channels but Not a Specific Connexin. PLoS ONE. 2015;10:e0125395 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Connexin 36 Polyclonal Antibody

Catalog # :

51-6300

Quantity :

100 µg

Price :

US 375.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: 0.1-1.0 µg/mL, Immunoprecipitation: 2-3 µg, Western Blot: 1.0 µg/mL

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20°C

Description :

Connexin-36 (CX36), is a member of the connexin gene family that is expressed predominantly in mammalian neurons. Connexins associate in groups of 6 and are organized radially around a central pore to form connexons. Each gap junction intercellular channel is formed by the conjunction of 2 connexons. Mutations in connexin-encoding genes can lead to functional and developmental abnormalities.

Immunogen :

Peptide corresponding to a sequence from the C-terminus of rat and mouse Connexin 36 (Cx36). This sequence differs from the human Cx36 protein by a single amino acid

Format :

Liquid

Applications w/Dilutions :

ELISA: 0.1-1.0 µg/mL, Immunoprecipitation: 2-3 µg, Western Blot: 1.0 µg/mL

Aliases :

connexin 36; connexin36; connexin-36; cx36; Gap junction alpha-9 protein; gap junction delta-2 protein; gap junction membrane channel protein alpha 9; gap junction protein delta 2; gap junction protein, alpha 9; gap junction protein, delta 2; gap junction protein, delta 2, 36kDa; GJA10; Gja9; GJD2

more info or order :

Invitrogen product webpage