Synapsin 1 Polyclonal Antibody | Invitrogen 51-5200 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Synapsin 1 Polyclonal Antibody

catalog :

51-5200

quantity :

10 ug

price :

US 434.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; rat; 1:1000; fig 1	Mahn M, Prigge M, Ron S, Levy R, Yizhar O. Biophysical constraints of optogenetic inhibition at presynaptic terminals. Nat Neurosci. 2016;19:554-6 pubmed publisher
western blot; human	Osborne C, West E, Nolan W, McHale Owen H, Williams A, Bate C. Glimepiride protects neurons against amyloid-Î²-induced synapse damage. Neuropharmacology. 2016;101:225-36 pubmed publisher
	Cho H, Yoo T, Moon H, Kang H, Yang Y, Kang M, et al. Adnp-mutant mice with cognitive inflexibility, CaMKIIα hyperactivity, and synaptic plasticity deficits. Mol Psychiatry. 2023;28:3548-3562 pubmed publisher
	Bassi J, Connelly A, Butler A, Liu Y, Ghanbari A, Farmer D, et al. Analysis of the distribution of vagal afferent projections from different peripheral organs to the nucleus of the solitary tract in rats. J Comp Neurol. 2022;530:3072-3103 pubmed publisher
	Gannon M, Wang B, Stringfellow S, Quintin S, Mendoza I, Srikantha T, et al. 14-3-3θ Does Not Protect against Behavioral or Pathological Deficits in Alzheimer's Disease Mouse Models. Eneuro. 2022;9: pubmed publisher
	Evans A, Park H, Saw N, Singhal K, Ogawa G, Leib R, et al. Age-related neuroinflammation and pathology in the locus coeruleus and hippocampus: beta-adrenergic antagonists exacerbate impairment of learning and memory in aged mice. Neurobiol Aging. 2021;106:241-256 pubmed publisher
	Yang N, Zhang Y, Wang J, Chen C, Song Y, Liang J, et al. Effects of Dexamethasone on Remodeling of the Hippocampal Synaptic Filamentous Actin Cytoskeleton in a Model of Pilocarpine-induced Status Epilepticus. Int J Med Sci. 2020;17:1683-1691 pubmed publisher
	Shi Y, Zhang L, Gao X, Zhang J, Ben Abou M, Liang G, et al. Intranasal Dantrolene as a Disease-Modifying Drug in Alzheimer 5XFAD Mice. J Alzheimers Dis. 2020;76:1375-1389 pubmed publisher
	Chau M, Deveau T, Song M, Wei Z, Gu X, Yu S, et al. Transplantation of iPS cell-derived neural progenitors overexpressing SDF-1? increases regeneration and functional recovery after ischemic stroke. Oncotarget. 2017;8:97537-97553 pubmed publisher
	Xiong T, Liu J, Dai G, Hou Y, Tan B, Zhang Y, et al. The progressive changes of filamentous actin cytoskeleton in the hippocampal neurons after pilocarpine-induced status epilepticus. Epilepsy Res. 2015;118:55-67 pubmed publisher
	Bate C, Williams A. cAMP-Inhibits Cytoplasmic Phospholipase Aâ‚‚ and Protects Neurons against Amyloid-Î²-Induced Synapse Damage. Biology (Basel). 2015;4:591-606 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Synapsin 1 Polyclonal Antibody

Catalog # :

51-5200

Quantity :

10 ug

Price :

US 434.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Bovine, Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:2,000, Immunohistochemistry: 1:2,000, Immunoprecipitation: 1 ug/200 ug rat brain lysate, Western Blot: 1:1,000

Species :

Bovine, Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

SYN1 (synapsin 1) is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins that associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains and are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. Synapsin 1 plays a role in regulation of axonogenesis and synaptogenesis. It serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Immunogen :

Purified bovine brain Synapsin 1

Format :

Lyophilized

Applications w/Dilutions :

Immunocytochemistry: 1:2,000, Immunohistochemistry: 1:2,000, Immunoprecipitation: 1 ug/200 ug rat brain lysate, Western Blot: 1:1,000

Aliases :

Brain protein 4.1; SYN1; Syn-1; SYN1a; SYN1b; Syn1-S; synapsin 1; synapsin I; synapsin Ia; synapsin Ib; synapsin-1; SYNI; truncated synapsin 1-S

more info or order :

Invitrogen product webpage