This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
HDAC2 Polyclonal Antibody
catalog :
51-5100
quantity :
100 ug
price :
US 520.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 11
Reference
Farini A, Tripodi L, Villa C, Strati F, Facoetti A, Baselli G, et al. Microbiota dysbiosis influences immune system and muscle pathophysiology of dystrophin-deficient mice. EMBO Mol Med. 2023;15:e16244 pubmed publisher
Zhu X, LeBoeuf M, Liu F, Grachtchouk M, Seykora J, Morrisey E, et al. HDAC1/2 Control Proliferation and Survival in Adult Epidermis and Pre‒Basal Cell Carcinoma through p16 and p53. J Invest Dermatol. 2022;142:77-87.e10 pubmed publisher
Lüdtke T, Wojahn I, Kleppa M, Schierstaedt J, Christoffels V, Künzler P, et al. Combined genomic and proteomic approaches reveal DNA binding sites and interaction partners of TBX2 in the developing lung. Respir Res. 2021;22:85 pubmed publisher
Tsugawa H, Kato C, Mori H, Matsuzaki J, Kameyama K, Saya H, et al. Cancer Stem-Cell Marker CD44v9-Positive Cells Arise From Helicobacter pylori-Infected CAPZA1-Overexpressing Cells. Cell Mol Gastroenterol Hepatol. 2019;: pubmed publisher
Yoon S, Kook T, Min H, Kwon D, Cho Y, Kim M, et al. PP2A negatively regulates the hypertrophic response by dephosphorylating HDAC2 S394 in the heart. Exp Mol Med. 2018;50:83 pubmed publisher
Shin H, Kapoor V, Kim G, Li P, Kim H, Suresh M, et al. Transient expression of ZBTB32 in anti-viral CD8+ T cells limits the magnitude of the effector response and the generation of memory. PLoS Pathog. 2017;13:e1006544 pubmed publisher
Kim T, Kang B, Jang H, Kwak S, Shin J, Kim H, et al. Ctbp2 Modulates NuRD-Mediated Deacetylation of H3K27 and Facilitates PRC2-Mediated H3K27me3 in Active Embryonic Stem Cell Genes During Exit from Pluripotency. Stem Cells. 2015;33:2442-55 pubmed publisher
Mani S, Kern C, Kimbrough D, Addy B, Kasiganesan H, Rivers W, et al. Inhibition of class I histone deacetylase activity represses matrix metalloproteinase-2 and -9 expression and preserves LV function postmyocardial infarction. Am J Physiol Heart Circ Physiol. 2015;308:H1391-401 pubmed publisher
Pinz S, Unser S, Buob D, Fischer P, Jobst B, Rascle A. Deacetylase inhibitors repress STAT5-mediated transcription by interfering with bromodomain and extra-terminal (BET) protein function. Nucleic Acids Res. 2015;43:3524-45 pubmed publisher
Harada A, Mallappa C, Okada S, Butler J, Baker S, Lawrence J, et al. Spatial re-organization of myogenic regulatory sequences temporally controls gene expression. Nucleic Acids Res. 2015;43:2008-21 pubmed publisher
Cho O, Mallappa C, Hernández Hernández J, Rivera Pérez J, Imbalzano A. Contrasting roles for MyoD in organizing myogenic promoter structures during embryonic skeletal muscle development. Dev Dyn. 2015;244:43-55 pubmed publisher
product information
Product Type :
Antibody
Product Name :
HDAC2 Polyclonal Antibody
Catalog # :
51-5100
Quantity :
100 ug
Price :
US 520.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
ChIP Assay: Assay-dependent, ELISA: 0.1-1.0 ug/mL, Immunocytochemistry: 5 ug/mL, Immunohistochemistry (Paraffin): 1:20, Immunoprecipitation: 5 ug, Western Blot: 1-3 ug/mL
Species :
Human, Mouse
Isotype :
IgG
Storage :
-20 C
Description :
HDAC2 belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.
Immunogen :
A synthetic 11 amino acid peptide derived from the C-terminus of the mouse HDAC2 protein.
Format :
Liquid
Applications w/Dilutions :
ChIP Assay: Assay-dependent, ELISA: 0.1-1.0 ug/mL, Immunocytochemistry: 5 ug/mL, Immunohistochemistry (Paraffin): 1:20, Immunoprecipitation: 5 ug, Western Blot: 1-3 ug/mL
Aliases :
D10Wsu179e; HD2; hdac 2; Hdac2; hdac-2; Histone deacetylase 2; histone deacetylase 2-like protein; histone deacetylase-2; I79_010219; mRPD3; RPD3; transcriptional regulator homolog RPD3; YAF1; YY1 transcription factor-binding protein; YY1-associated factor 1; Yy1bp
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA