SMAD3 Polyclonal Antibody | Invitrogen 51-1500 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SMAD3 Polyclonal Antibody

catalog :

51-1500

quantity :

100 µg

price :

425 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

more info or order :

Invitrogen product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse; 1:250; loading ...; fig 4a western blot; mouse; loading ...; fig 4b	Chowdhury A, Hasselbach L, Echtermeyer F, Jyotsana N, Theilmeier G, Herzog C. Fibulin-6 regulates pro-fibrotic TGF-β responses in neonatal mouse ventricular cardiac fibroblasts. Sci Rep. 2017;7:42725 pubmed publisher
western blot; rat; 1:1000; loading ...; fig 7b	Zhu Y, Takayama T, Wang B, Kent A, Zhang M, Binder B, et al. Restenosis Inhibition and Re-differentiation of TGFβ/Smad3-activated Smooth Muscle Cells by Resveratrol. Sci Rep. 2017;7:41916 pubmed publisher
western blot; human; loading ...; fig 3f	Lefort K, Ostano P, Mello Grand M, Calpini V, Scatolini M, Farsetti A, et al. Dual tumor suppressing and promoting function of Notch1 signaling in human prostate cancer. Oncotarget. 2016;7:48011-48026 pubmed publisher
	Devocelle A, Lecru L, Francois H, Desterke C, Gallerne C, Eid P, et al. Inhibition of TGF-β1 Signaling by IL-15: A Novel Role for IL-15 in the Control of Renal Epithelial-Mesenchymal Transition: IL-15 Counteracts TGF-β1-Induced EMT in Renal Fibrosis. Int J Cell Biol. 2019;2019:9151394 pubmed publisher
	Oh S, Shin S, Song H, Grande J, Janknecht R. Relationship between ETS Transcription Factor ETV1 and TGF-β-regulated SMAD Proteins in Prostate Cancer. Sci Rep. 2019;9:8186 pubmed publisher
	Xu H, Li F. miR‑127 aggravates myocardial failure by promoting the TGF‑β1/Smad3 signaling. Mol Med Rep. 2018;18:4839-4846 pubmed publisher
	Albers R, Selesniemi K, Natale D, Brown T. TGF-β induces Smad2 Phosphorylation, ARE Induction, and Trophoblast Differentiation. Int J Stem Cells. 2018;11:111-120 pubmed publisher
	Feng M, Tang P, Huang X, Sun S, You Y, Xiao J, et al. TGF-β Mediates Renal Fibrosis via the Smad3-Erbb4-IR Long Noncoding RNA Axis. Mol Ther. 2018;26:148-161 pubmed publisher
	Sakr S, Abdulfatah E, Thomas S, Al Wahab Z, Beydoun R, Morris R, et al. Granulosa Cell Tumors: Novel Predictors of Recurrence in Early-stage Patients. Int J Gynecol Pathol. 2017;36:240-252 pubmed publisher

product information

Product Type :

Antibody

Product Name :

SMAD3 Polyclonal Antibody

Catalog # :

51-1500

Quantity :

100 µg

Price :

425 USD

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

ChIP assay: 2 µg/10^6 cells, ELISA: 0.1-1.0 µg/mL, Immunocytochemistry: 1:100-1:500, Immunofluorescence: 1:100-1:500, Immunohistochemistry: 1.0 µg/mL, Western Blot: 1-3 µg/mL

Species :

Human

Isotype :

IgG

Storage :

-20°C

Description :

SMAD3 belongs to the SMAD family of proteins. They are similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

Immunogen :

A 20 amino acid synthetic peptide derived from a central portion of the linker domain of human Smad3

Format :

Liquid

Applications w/Dilutions :

ChIP assay: 2 µg/10^6 cells, ELISA: 0.1-1.0 µg/mL, Immunocytochemistry: 1:100-1:500, Immunofluorescence: 1:100-1:500, Immunohistochemistry: 1.0 µg/mL, Western Blot: 1-3 µg/mL

Aliases :

AU022421; DKFZp586N0721; DKFZp686J10186; hMAD-3; hSMAD3; HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MAD (mothers against decapentaplegic, Drosophila) homolog 3; MAD homolog 3; MAD homolog 3a; mad homolog JV15-2; mad protein homolog; MAD, mothers against decapentaplegic homolog 3; mad3; MAD-3; madh3; madh3a; madh3-A; MGC60396; mMad3; mothers against decapentaplegic homolog 3; mothers against DPP homolog 3; SMA- and MAD-related protein 3; SMAD; Smad 3; SMAD family member 3; SMAD family member 3 L homeolog; SMAD family member 3a; SMAD, mothers against DPP homolog 3; Smad3; smad3.L; smad3a; TGF beta response effector Smad3; TGF-beta response effector Smad3; transcription factor; transcription factor Smad3; wu:fa99e03; XELAEV_18018454mg; XenMLP; Xmad3; XSmad3

more info or order :

Invitrogen product webpage