NFkB p65 Polyclonal Antibody | Invitrogen 51-0500 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

NFkB p65 Polyclonal Antibody

catalog :

51-0500

quantity :

100 µg

price :

425 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; rat; 1:250	Yapislar H, Taşkın E, Ozdas S, Akin D, Sonmez E. Counteraction of Apoptotic and Inflammatory Effects of Adriamycin in the Liver Cell Culture by Clinopitolite. Biol Trace Elem Res. 2016;170:373-81 pubmed publisher
	Fauzia E, Barbhuyan T, Shrivastava A, Kumar M, Garg P, Khan M, et al. Chick Embryo: A Preclinical Model for Understanding Ischemia-Reperfusion Mechanism. Front Pharmacol. 2018;9:1034 pubmed publisher
	Paredes J, Ji P, Lacomb J, Shroyer K, Martello L, Williams J. Establishment of three novel cell lines derived from African American patients with colorectal carcinoma: A unique tool for assessing racial health disparity. Int J Oncol. 2018;53:1516-1528 pubmed publisher

product information

Product Type :

Antibody

Product Name :

NFkB p65 Polyclonal Antibody

Catalog # :

51-0500

Quantity :

100 µg

Price :

425 USD

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Non-human primate

Applications :

ChIP assay: 5 µg, ELISA: 0.1-1.0 µg/mL, Immunocytochemistry: 1:100-1:500, Immunofluorescence: 1:100-1:500, Immunohistochemistry: 0.5-2 µg/mL, Western Blot: 1-3 µg/mL

Species :

Human, Mouse, Non-human primate

Isotype :

IgG

Storage :

-20°C

Description :

Nuclear factor kB p65 (NF-kB p65) is encoded by the RELA gene and is present on chromosome 11 in humans. NF-kB P65 is also known as RelA (v-rel avian reticuloendotheliosis viral oncogene homolog A) and belongs to the Rel family of proteins. It is one of the two subunits of NF-kB (Nuclear factor kappa-light-chain-enhancer of activated B cells) that heterodimerizes with the other subunits p50 or p52. However, binding of TNF alpha to its cognate receptor phosphorylates IKK which in turn phosphorylates I kB allowing proteasomal degradation of I kB. Phosphorylation of p65 at Ser 536 located in the carboxy-terminal transactivation domains (TAD) leads to nuclear localization of the transcriptionally active complex and NF-kB mediated transactivation of several downstream genes. It specifically plays a key role in transcription of immunoglobulin k (kappa) gene in mature B-lymphoid cells.

Immunogen :

A recombinant protein derived from the carboxyl terminal portion of the human NF-kappa-beta protein

Format :

Liquid

Applications w/Dilutions :

ChIP assay: 5 µg, ELISA: 0.1-1.0 µg/mL, Immunocytochemistry: 1:100-1:500, Immunofluorescence: 1:100-1:500, Immunohistochemistry: 0.5-2 µg/mL, Western Blot: 1-3 µg/mL

Aliases :

avian reticuloendotheliosis viral (v-rel) oncogene homolog A; EBP-1; I79_021812; MGC131774; NF KB; NFkappaB p65; nf-kappa-b p65; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NF-kappaB transcription factor p65 subunit; NFkB; NF-kB p65 subunit; nfkb rela; NFKB1; nfkb3; NFkB-p50; nuclear factor; nuclear factor kappa b; nuclear factor kappa B subunit p65; nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; p65 NF kappaB; p65 NF-kappa B; p65 NFkB; P65 transcription factor; putative transcription factor p65 homolog; REL A; rel1; rela; RELA proto-oncogene, NF-kB subunit; rela.L; rela-a; transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel avian reticuloendotheliosis viral oncogene homolog A L homeolog; v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65; XELAEV_18022301mg; Xrel1; xrela

more info or order :

Invitrogen product webpage