DLL4 (soluble) Polyclonal Antibody, PeproTech | Invitrogen 500-P279-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

DLL4 (soluble) Polyclonal Antibody, PeproTech

catalog :

500-P279-100UG

quantity :

100 ug

price :

US 304.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA

product information

Product Type :

Antibody

Product Name :

DLL4 (soluble) Polyclonal Antibody, PeproTech

Catalog # :

500-P279-100UG

Quantity :

100 ug

Price :

US 304.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

ELISA: 0.5-2.0 ug/mL, Western Blot: 0.1-0.2 ug/mL

Species :

Human

Storage :

-20 C

Description :

Delta-like ligand 4 (DLL4), also know as Delta-4, is a homologue of the Drosophila delta protein, and functions as a transmembrane bound ligand to the notch receptor Notch1. DLL4 is expressed in the vasculature and plays a critical role in vascular development. It is induced by vascular endothelial growth factor (VEGF), as a negative feedback regulator to regulate angiogenic sprouting and promote the formulation of a differentiated vascular network. DLL4 has been found to be strongly expressed in tumor vessels of clear-cell renal tumors and bladder cancer, and inhibition of DLL4 results in increased vascular proliferation but defective maturation. This in turn leads to a decrease in tumor growth, with no apparent toxicity.

Immunogen :

HEK293 cells-derived Recombinant Human sDLL-4

Format :

Lyophilized

Applications w/Dilutions :

ELISA: 0.5-2.0 ug/mL, Western Blot: 0.1-0.2 ug/mL

Aliases :

AOS6; delta 4; delta ligand 4; delta like canonical Notch ligand 4; Delta4; delta-like 4 (Drosophila); delta-like 4 homolog; delta-like 4 protein; delta-like protein 4; DLL4; Drosophila Delta homolog 4; hdelta2; MGC126344; notch ligand delta-2; notch ligand DLL4; UNQ1895/PRO4341