TSLP Polyclonal Antibody, PeproTech | Invitrogen 500-P258-1MG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TSLP Polyclonal Antibody, PeproTech

catalog :

500-P258-1MG

quantity :

1 mg

price :

US 2070.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA

citations: 1

Reference
Hedl M, Sun R, Huang C, Abraham C. STAT3 and STAT5 Signaling Thresholds Determine Distinct Regulation for Innate Receptor-Induced Inflammatory Cytokines, and STAT3/STAT5 Disease Variants Modulate These Outcomes. J Immunol. 2019;203:3325-3338 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TSLP Polyclonal Antibody, PeproTech

Catalog # :

500-P258-1MG

Quantity :

1 mg

Price :

US 2070.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

ELISA: 0.5-2.0 ug/mL, Western Blot: 0.1-0.2 ug/mL

Species :

Human

Storage :

-20 C

Description :

TSLP is a 159 amino acid four helix-bundle hemopoietic cytokine that signals through a heterodimeric receptor complex consisting of the human TSLP receptor and the IL-7R alpha-chain. It impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes, enhances the maturation of CD11c (+) dendritic cells, naive CD4 (+), and CD8 (+) T cells into proallergic effectors, and primes dendritic cells to produce large amounts of IL-12 after CD40 ligand stimulation. TSLP influences the regulation of the positive selection of regulatory T cells and maintenance of peripheral CD4 (+) T cell homeostasis. It induces allergic inflammation by directly activating mast cells and may be involved in the pathophysiology of inflammatory arthritis. It is expressed in heart, liver and prostate.

Immunogen :

E.coli-derived Recombinant Human TSLP

Format :

Lyophilized

Applications w/Dilutions :

ELISA: 0.5-2.0 ug/mL, Western Blot: 0.1-0.2 ug/mL

Aliases :

Thymic stroma-derived lymphopoietin; thymic stromal lymphopoietin; TSLP