beta-2 Defensin Polyclonal Antibody, PeproTech | Invitrogen 500-P161G-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

beta-2 Defensin Polyclonal Antibody, PeproTech

catalog :

500-P161G-100UG

quantity :

100 ug

price :

US 304.00

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA

citations: 2

Reference
Zhang L, Ghosh S, Basavarajappa S, Chen Y, Shrestha P, Penfield J, et al. HBD-2 binds SARS-CoV-2 RBD and blocks viral entry: Strategy to combat COVID-19. iScience. 2022;25:103856 pubmed publisher
Stanton A, Mowbray C, Lanz M, Brown K, Hilton P, Tyson Capper A, et al. Topical Estrogen Treatment Augments the Vaginal Response to Escherichia coli Flagellin. Sci Rep. 2020;10:8473 pubmed publisher

product information

Product Type :

Antibody

Product Name :

beta-2 Defensin Polyclonal Antibody, PeproTech

Catalog # :

500-P161G-100UG

Quantity :

100 ug

Price :

US 304.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Goat

Reactivity :

Human

Applications :

ELISA: 0.5-2.0 ug/mL, Western Blot: 0.1-0.2 ug/mL

Species :

Human

Storage :

-20 C

Description :

Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The alpha-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, six human beta-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds.

Immunogen :

E.coli-derived Recombinant Human BD-2

Format :

Lyophilized

Applications w/Dilutions :

ELISA: 0.5-2.0 ug/mL, Western Blot: 0.1-0.2 ug/mL

Aliases :

BD-2; beta defensin 2; beta defensin-2; Beta-defensin 2; Beta-defensin 4A; DEFB102; DEFB2; DEFB-2; DEFB4; DEFB4A; DEFB4B; Defensin beta 2; defensin beta 4A; Defensin beta2; defensin, beta 2; defensin, beta 4; defensin, beta 4A; Defensin-beta2; HBD-2; SAP1; Skin-antimicrobial peptide 1