RUNX3 Monoclonal Antibody (R3-5G4), eFluor 660, eBioscience | Invitrogen 50-9817-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RUNX3 Monoclonal Antibody (R3-5G4), eFluor 660, eBioscience

catalog :

50-9817-82

quantity :

100 µg

price :

US 398

clonality :

monoclonal

host :

mouse

conjugate :

efluor 660

clone name :

R3-5G4

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 2

Reference
Lin J, Izar B, Wang S, Yapp C, Mei S, Shah P, et al. Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes. elife. 2018;7: pubmed publisher
Hu T, Wang H, Simmons A, Bajana S, Zhao Y, Kovats S, et al. Increased level of E protein activity during invariant NKT development promotes differentiation of invariant NKT2 and invariant NKT17 subsets. J Immunol. 2013;191:5065-73 pubmed publisher

product information

Product Type :

Antibody

Product Name :

RUNX3 Monoclonal Antibody (R3-5G4), eFluor 660, eBioscience

Catalog # :

50-9817-82

Quantity :

100 µg

Price :

US 398

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Immunocytochemistry: 10 µg/mL, Immunohistochemistry (Paraffin): 10 µg/mL

Species :

Human

Clone :

R3-5G4

Isotype :

IgG1, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 10 µg/mL, Immunohistochemistry (Paraffin): 10 µg/mL

Aliases :

Acute myeloid leukemia 2 protein; acute myeloid leukemia gene 2; AML2; CBFA3; CBF-alpha 3; CBF-alpha-3; core binding factor alpha 3; core-binding factor subunit alpha-3; core-binding factor, runt domain, alpha subunit 3; oncogene AML-2; PEA2 alpha C; PEA2-alpha C; PEBP2 alpha C; PEBP2A3; PEBP2aC; PEBP2-alpha C; polyomavirus enhancer-binding protein 2 alpha C subunit; runt domain, alpha subunit 3; Runt related transcription factor 3; runt-related transcription factor 3; RUNX3; SL3/AKV core-binding factor alpha C subunit; SL3-3 enhancer factor 1 alpha C subunit; transcription factor AML2; transcription factor AML2/CBFA3