Granzyme M Monoclonal Antibody (4B2G4), eFluor 660, eBioscience | Invitrogen 50-9774-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Granzyme M Monoclonal Antibody (4B2G4), eFluor 660, eBioscience

catalog :

50-9774-42

quantity :

100 Tests

price :

US 472.00

clonality :

monoclonal

host :

mouse

conjugate :

efluor 660

clone name :

4B2G4

reactivity :

human

application :

flow cytometry

citations: 6

Reference
Nguyen T, Rowntree L, Petersen J, Chua B, Hensen L, Kedzierski L, et al. CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope display high naive precursor frequency and TCR promiscuity. Immunity. 2021;54:1066-1082.e5 pubmed publisher
Sant S, Jenkins M, Dash P, Watson K, Wang Z, Pizzolla A, et al. Human γδ T-cell receptor repertoire is shaped by influenza viruses, age and tissue compartmentalisation. Clin Transl Immunology. 2019;8:e1079 pubmed publisher
Clayton K, Collins D, Lengieza J, Ghebremichael M, Dotiwala F, Lieberman J, et al. Resistance of HIV-infected macrophages to CD8+ T lymphocyte-mediated killing drives activation of the immune system. Nat Immunol. 2018;19:475-486 pubmed publisher
Van Domselaar R, de Poot S, Remmerswaal E, Lai K, Ten Berge I, Bovenschen N. Granzyme M targets host cell hnRNP K that is essential for human cytomegalovirus replication. Cell Death Differ. 2013;20:419-29 pubmed publisher
de Poot S, Westgeest M, Hostetter D, Van Damme P, Plasman K, Demeyer K, et al. Human and mouse granzyme M display divergent and species-specific substrate specificities. Biochem J. 2011;437:431-42 pubmed publisher
Anthony D, Andrews D, Chow M, Watt S, House C, Akira S, et al. A role for granzyme M in TLR4-driven inflammation and endotoxicosis. J Immunol. 2010;185:1794-803 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Granzyme M Monoclonal Antibody (4B2G4), eFluor 660, eBioscience

Catalog # :

50-9774-42

Quantity :

100 Tests

Price :

US 472.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (0.125 ug)/test

Species :

Human

Clone :

4B2G4

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha- tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.125 ug)/test

Aliases :

granzyme M; granzyme M (lymphocyte met-ase 1); GZMM; Hu-Met-1; Lmet1; lymphoctye Met-ase 1; lymphocyte met-ase 1; MET1; Met-1 serine protease; Met-ase; MMET-1; natural killer cell granular protease; RNK-Met-1