TIGIT Monoclonal Antibody (GIGD7), eFluor™ 660, eBioscience | Invitrogen 50-9501-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TIGIT Monoclonal Antibody (GIGD7), eFluor™ 660, eBioscience

catalog :

50-9501-82

quantity :

100 µg

price :

US 421

clonality :

monoclonal

host :

rat

conjugate :

efluor 660

clone name :

GIGD7

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; fig 3	Thiault N, Darrigues J, Adoue V, Gros M, Binet B, Pérals C, et al. Peripheral regulatory T lymphocytes recirculating to the thymus suppress the development of their precursors. Nat Immunol. 2015;16:628-34 pubmed publisher
	Chen X, MacNabb B, Flood B, Blazar B, Kline J. Divergent fates of antigen-specific CD8+ T cell clones in mice with acute leukemia. Cell Rep. 2021;37:109991 pubmed publisher
	Vasanthakumar A, Chisanga D, Blume J, Gloury R, Britt K, Henstridge D, et al. Sex-specific adipose tissue imprinting of regulatory T cells. Nature. 2020;579:581-585 pubmed publisher
	Sidwell T, Liao Y, Garnham A, Vasanthakumar A, Gloury R, Blume J, et al. Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis. Nat Commun. 2020;11:252 pubmed publisher
	Di Marco Barros R, Roberts N, Dart R, Vantourout P, Jandke A, Nussbaumer O, et al. Epithelia Use Butyrophilin-like Molecules to Shape Organ-Specific Î³Î´ T Cell Compartments. Cell. 2016;167:203-218.e17 pubmed publisher
	Ferguson B, Liu R, Rolle C, Tan Y, Krasnoperov V, Kanteti R, et al. The EphB4 receptor tyrosine kinase promotes lung cancer growth: a potential novel therapeutic target. PLoS ONE. 2013;8:e67668 pubmed publisher
	Koyama M, Kuns R, Olver S, Lineburg K, Lor M, Teal B, et al. Promoting regulation via the inhibition of DNAM-1 after transplantation. Blood. 2013;121:3511-20 pubmed publisher
	Stanietsky N, Simic H, Arapovic J, Toporik A, Levy O, Novik A, et al. The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity. Proc Natl Acad Sci U S A. 2009;106:17858-63 pubmed publisher
	Seth S, Ravens I, Kremmer E, Maier M, Hadis U, Hardtke S, et al. Abundance of follicular helper T cells in Peyer's patches is modulated by CD155. Eur J Immunol. 2009;39:3160-70 pubmed publisher
	Boles K, Vermi W, Facchetti F, Fuchs A, Wilson T, Diacovo T, et al. A novel molecular interaction for the adhesion of follicular CD4 T cells to follicular DC. Eur J Immunol. 2009;39:695-703 pubmed publisher
	Yu X, Harden K, Gonzalez L, Francesco M, Chiang E, Irving B, et al. The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells. Nat Immunol. 2009;10:48-57 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TIGIT Monoclonal Antibody (GIGD7), eFluor™ 660, eBioscience

Catalog # :

50-9501-82

Quantity :

100 µg

Price :

US 421

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 1 µg/test

Species :

Mouse

Clone :

GIGD7

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.

Immunogen :

mTIGIT-Fc treated with 4% PFA

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 µg/test

Aliases :

ENSMUSG00000071552; T cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; TIGIT; V-set and immunoglobulin domain containing 9; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain containing 3; V-set and transmembrane domain-containing protein 3; VSIG9; VSTM3; Washington University cell adhesion molecule; WUCAM

more info or order :

Invitrogen product webpage