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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Granzyme K Monoclonal Antibody (G3H69), eFluor 660, eBioscience™
catalog :
50-8897-42
quantity :
100 Tests
price :
US 309.00
clonality :
monoclonal
host :
mouse
conjugate :
efluor 660
clone name :
G3H69
reactivity :
human
application :
flow cytometry
more info or order :
Invitrogen product webpage
citations: 3
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 4a
Srivastava R, Khan A, Garg S, Syed S, Furness J, Vahed H, et al. Human Asymptomatic Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP13/14 (UL47) Preferentially Recall Polyfunctional Effector Memory CD44high CD62Llow CD8+ TEM Cells and Protect Humanized HLA-A*02:01 Transgenic Mice against Ocula. J Virol. 2017;91: pubmed publisher
Bovenschen N, Quadir R, van den Berg A, Brenkman A, Vandenberghe I, Devreese B, et al. Granzyme K displays highly restricted substrate specificity that only partially overlaps with granzyme A. J Biol Chem. 2009;284:3504-12 pubmed publisher
Shresta S, Goda P, Wesselschmidt R, Ley T. Residual cytotoxicity and granzyme K expression in granzyme A-deficient cytotoxic lymphocytes. J Biol Chem. 1997;272:20236-44 pubmed
product information
Product Type :
Antibody
Product Name :
Granzyme K Monoclonal Antibody (G3H69), eFluor 660, eBioscience™
Catalog # :
50-8897-42
Quantity :
100 Tests
Price :
US 309.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 5 µL (0.03 µg)/test
Species :
Human
Clone :
G3H69
Isotype :
IgG2a, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
Granzyme K (GrK) belongs to a family of trypsin-like serine proteases localised in the cytotoxic granules of activated T cells and NK cells. It encodes a 28 kDa serine protease whose gene is located on chromosome 5q11-12 close to the granzyme A-encoding gene. Like granzyme A, it has a trypsin-like specifity cleaving at the basic residues arginine and lysine. Granzyme K triggers rapid cell death independently of caspase activation with single-stranded DNA nicks and is primarily expressed in thymus, lung, spleen and peripheral blood leukocytes.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 µL (0.03 µg)/test
Aliases :
Fragmentin-3; granzyme 3; granzyme K; granzyme K (granzyme 3; tryptase II); granzyme K (serine protease, granzyme 3; tryptase II); granzyme-3; GrK; GZMK; NK-Tryp-2; NK-tryptase-2; RNK-Tryp-2; TRYP2; tryptase II
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA