IL-4 Monoclonal Antibody (OX81), eFluor 660, eBioscience™ | Invitrogen 50-7045-80 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IL-4 Monoclonal Antibody (OX81), eFluor 660, eBioscience™

catalog :

50-7045-80

quantity :

25µg

price :

US 119

clonality :

monoclonal

host :

mouse

conjugate :

efluor 660

clone name :

OX81

reactivity :

rat

application :

flow cytometry

citations: 4

Reference
Hilliard L, Colafella K, Bulmer L, Puelles V, Singh R, Ow C, et al. Chronic recurrent dehydration associated with periodic water intake exacerbates hypertension and promotes renal damage in male spontaneously hypertensive rats. Sci Rep. 2016;6:33855 pubmed publisher
Chakir H, Wang H, Lefebvre D, Webb J, Scott F. T-bet/GATA-3 ratio as a measure of the Th1/Th2 cytokine profile in mixed cell populations: predominant role of GATA-3. J Immunol Methods. 2003;278:157-69 pubmed
Caraher E, Parenteau M, Gruber H, Scott F. Flow cytometric analysis of intracellular IFN-gamma, IL-4 and IL-10 in CD3(+)4(+) T-cells from rat spleen. J Immunol Methods. 2000;244:29-40 pubmed
Ramirez F, Fowell D, Puklavec M, Simmonds S, Mason D. Glucocorticoids promote a TH2 cytokine response by CD4+ T cells in vitro. J Immunol. 1996;156:2406-12 pubmed

product information

Product Type :

Antibody

Product Name :

IL-4 Monoclonal Antibody (OX81), eFluor 660, eBioscience™

Catalog # :

50-7045-80

Quantity :

25µg

Price :

US 119

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Rat

Applications :

Flow Cytometry: 0.5 µg/test

Species :

Rat

Clone :

OX81

Isotype :

IgG1, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 µg/test

Aliases :

Interleukin-4, BSF1, IL-4, Lymphocyte stimulatory factor 1, MGC79402