product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
GL7 Monoclonal Antibody (GL-7 (GL7)), eFluor™ 660, eBioscience
catalog :
50-5902-82
quantity :
100 µg
price :
US 311
clonality :
monoclonal
host :
rat
conjugate :
efluor 660
clone name :
GL-7 (GL7)
reactivity :
human, mouse
application :
flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 42
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 1e
Raso F, Sagadiev S, Du S, Gage E, Arkatkar T, Metzler G, et al. αv Integrins regulate germinal center B cell responses through noncanonical autophagy. J Clin Invest. 2018;128:4163-4178 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; fig 3g
Bemark M, Hazanov H, Strömberg A, Komban R, Holmqvist J, Köster S, et al. Limited clonal relatedness between gut IgA plasma cells and memory B cells after oral immunization. Nat Commun. 2016;7:12698 pubmed publisher
Hidalgo Villeda F, Million M, Defoort C, Vannier T, Svilar L, Lagier M, et al. Prolonged dysbiosis and altered immunity under nutritional intervention in a physiological mouse model of severe acute malnutrition. iScience. 2023;26:106910 pubmed publisher
H xe4 ggl xf6 f T, Cipolla M, Loewe M, Chen S, Mesin L, Hartweger H, et al. Continuous germinal center invasion contributes to the diversity of the immune response. Cell. 2023;186:147-161.e15 pubmed publisher
Omer Javed A, Pedrazzani G, Albano L, Ghaus S, Latroche C, Manzi M, et al. Mobilization-based chemotherapy-free engraftment of gene-edited human hematopoietic stem cells. Cell. 2022;185:2248-2264.e21 pubmed publisher
Xing Y, Guo W, Wu M, Xie J, Huang D, Hu P, et al. An orally available small molecule BCL6 inhibitor effectively suppresses diffuse large B cell lymphoma cells growth in vitro and in vivo. Cancer Lett. 2022;529:100-111 pubmed publisher
Viant C, Escolano A, Chen S, Nussenzweig M. Sequencing, cloning, and antigen binding analysis of monoclonal antibodies isolated from single mouse B cells. STAR Protoc. 2021;2:100389 pubmed publisher
Juillard F, de Miranda M, Li S, Franco A, Seixas A, Liu B, et al. KSHV LANA acetylation-selective acidic domain reader sequence mediates virus persistence. Proc Natl Acad Sci U S A. 2020;117:22443-22451 pubmed publisher
Rosser E, Piper C, Matei D, Blair P, Rendeiro A, Orford M, et al. Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells. Cell Metab. 2020;31:837-851.e10 pubmed publisher
Schmitt M, Lutz J, Haase P, B xf6 sl M, Wienands J, Engels N, et al. The B-cell antigen receptor of IgE-switched plasma cells regulates memory IgE responses. J Allergy Clin Immunol. 2020;146:642-651.e5 pubmed publisher
Kimura S, Nakamura Y, Kobayashi N, Shiroguchi K, Kawakami E, Mutoh M, et al. Osteoprotegerin-dependent M cell self-regulation balances gut infection and immunity. Nat Commun. 2020;11:234 pubmed publisher
Komban R, Strömberg A, Biram A, Cervin J, Lebrero Fernández C, Mabbott N, et al. Activated Peyer's patch B cells sample antigen directly from M cells in the subepithelial dome. Nat Commun. 2019;10:2423 pubmed publisher
Pires de Miranda M, Quendera A, McVey C, Kaye K, Simas J. In Vivo Persistence of Chimeric Virus after Substitution of the Kaposi's Sarcoma-Associated Herpesvirus LANA DNA Binding Domain with That of Murid Herpesvirus 4. J Virol. 2018;92: pubmed publisher
Kenderes K, Levack R, Papillion A, Cabrera Martinez B, Dishaw L, Winslow G. T-Bet+ IgM Memory Cells Generate Multi-lineage Effector B Cells. Cell Rep. 2018;24:824-837.e3 pubmed publisher
Zhang C, Wang C, Jiang M, Gu C, Xiao J, Chen X, et al. Act1 is a negative regulator in T and B cells via direct inhibition of STAT3. Nat Commun. 2018;9:2745 pubmed publisher
Barwick B, Scharer C, Martinez R, Price M, Wein A, Haines R, et al. B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation. Nat Commun. 2018;9:1900 pubmed publisher
Liu J, Huang X, Hao S, Wang Y, Liu M, Xu J, et al. Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus. Nat Commun. 2018;9:1136 pubmed publisher
Guo M, Price M, Patterson D, Barwick B, Haines R, Kania A, et al. EZH2 Represses the B Cell Transcriptional Program and Regulates Antibody-Secreting Cell Metabolism and Antibody Production. J Immunol. 2018;200:1039-1052 pubmed publisher
Wang X, Zhang Y, Wang Z, Liu X, Zhu G, Han G, et al. Anti?IL?39 (IL?23p19/Ebi3) polyclonal antibodies ameliorate autoimmune symptoms in lupus?like mice. Mol Med Rep. 2017;: pubmed publisher
Deng R, Hurtz C, Song Q, Yue C, Xiao G, Yu H, et al. Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease. Nat Commun. 2017;8:978 pubmed publisher
Sun J, Holmgren J, Larena M, Terrinoni M, Fang Y, Bresnick A, et al. Deficiency in Calcium-Binding Protein S100A4 Impairs the Adjuvant Action of Cholera Toxin. Front Immunol. 2017;8:1119 pubmed publisher
Westerterp M, Gautier E, Ganda A, Molusky M, Wang W, Fotakis P, et al. Cholesterol Accumulation in Dendritic Cells Links the Inflammasome to Acquired Immunity. Cell Metab. 2017;25:1294-1304.e6 pubmed publisher
Schmitt M, Sitte S, Voehringer D. CD4 T Helper Cells Instruct Lymphopenia-Induced Memory-Like CD8 T Cells for Control of Acute LCMV Infection. Front Immunol. 2016;7:622 pubmed publisher
Hilpert C, Sitte S, Matthies A, Voehringer D. Dendritic Cells Are Dispensable for T Cell Priming and Control of Acute Lymphocytic Choriomeningitis Virus Infection. J Immunol. 2016;197:2780-6 pubmed publisher
Andersson S, Eneljung T, Tengvall S, Jirholt P, Stern A, Henningsson L, et al. Collagen epitope expression on B cells is sufficient to confer tolerance to collagen-induced arthritis. Arthritis Res Ther. 2016;18:140 pubmed publisher
Wöhner M, Tagoh H, Bilic I, Jaritz M, Poliakova D, Fischer M, et al. Molecular functions of the transcription factors E2A and E2-2 in controlling germinal center B cell and plasma cell development. J Exp Med. 2016;213:1201-21 pubmed publisher
de Valle E, Grigoriadis G, O Reilly L, Willis S, Maxwell M, Corcoran L, et al. NF?B1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells. J Exp Med. 2016;213:621-41 pubmed publisher
Matar C, Anthony N, O Flaherty B, Jacobs N, Priyamvada L, Engwerda C, et al. Gammaherpesvirus Co-infection with Malaria Suppresses Anti-parasitic Humoral Immunity. PLoS Pathog. 2015;11:e1004858 pubmed publisher
Collins C, Speck S. Interleukin 21 signaling in B cells is required for efficient establishment of murine gammaherpesvirus latency. PLoS Pathog. 2015;11:e1004831 pubmed publisher
Funakoshi S, Shimizu T, Numata O, Ato M, Melchers F, Ohnishi K. BILL-cadherin/cadherin-17 contributes to the survival of memory B cells. PLoS ONE. 2015;10:e0117566 pubmed publisher
Senejani A, Liu Y, Kidane D, Maher S, Zeiss C, Park H, et al. Mutation of POLB causes lupus in mice. Cell Rep. 2014;6:1-8 pubmed publisher
Hua Z, Gross A, Lamagna C, Ramos Hernández N, Scapini P, Ji M, et al. Requirement for MyD88 signaling in B cells and dendritic cells for germinal center anti-nuclear antibody production in Lyn-deficient mice. J Immunol. 2014;192:875-85 pubmed publisher
Panda S, Zhang J, Tan N, Ho B, Ding J. Natural IgG antibodies provide innate protection against ficolin-opsonized bacteria. EMBO J. 2013;32:2905-19 pubmed publisher
Block K, Huang H. The cellular source and target of IL-21 in K/BxN autoimmune arthritis. J Immunol. 2013;191:2948-55 pubmed publisher
Detre C, Yigit B, Keszei M, Castro W, Magelky E, Terhorst C. SAP modulates B cell functions in a genetic background-dependent manner. Immunol Lett. 2013;153:15-21 pubmed publisher
Freire T, Zhang X, Deriaud E, Ganneau C, Vichier Guerre S, Azria E, et al. Glycosidic Tn-based vaccines targeting dermal dendritic cells favor germinal center B-cell development and potent antibody response in the absence of adjuvant. Blood. 2010;116:3526-36 pubmed publisher
Liu Y, Zhang W. Identification of a new transmembrane adaptor protein that constitutively binds Grb2 in B cells. J Leukoc Biol. 2008;84:842-51 pubmed publisher
DiLillo D, Hamaguchi Y, Ueda Y, Yang K, Uchida J, Haas K, et al. Maintenance of long-lived plasma cells and serological memory despite mature and memory B cell depletion during CD20 immunotherapy in mice. J Immunol. 2008;180:361-71 pubmed
El Shikh M, El Sayed R, Wu Y, Szakal A, Tew J. TLR4 on follicular dendritic cells: an activation pathway that promotes accessory activity. J Immunol. 2007;179:4444-50 pubmed
Kimura N, Ohmori K, Miyazaki K, Izawa M, Matsuzaki Y, Yasuda Y, et al. Human B-lymphocytes express alpha2-6-sialylated 6-sulfo-N-acetyllactosamine serving as a preferred ligand for CD22/Siglec-2. J Biol Chem. 2007;282:32200-7 pubmed
Meier D, Bornmann C, Chappaz S, Schmutz S, Otten L, Ceredig R, et al. Ectopic lymphoid-organ development occurs through interleukin 7-mediated enhanced survival of lymphoid-tissue-inducer cells. Immunity. 2007;26:643-54 pubmed
Genton C, Wang Y, Izui S, Malissen B, Delsol G, Fournié G, et al. The Th2 lymphoproliferation developing in LatY136F mutant mice triggers polyclonal B cell activation and systemic autoimmunity. J Immunol. 2006;177:2285-93 pubmed
product information
Product Type :
Antibody
Product Name :
GL7 Monoclonal Antibody (GL-7 (GL7)), eFluor™ 660, eBioscience
Catalog # :
50-5902-82
Quantity :
100 µg
Price :
US 311
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Human, Mouse
Applications :
Flow Cytometry: 0.25 µg/test
Species :
Human, Mouse
Clone :
GL-7 (GL7)
Isotype :
IgM
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
GL7 is a cell-surface protein found on T and B lymphocytes activated in vitro, on bone marrow pre-B-II cells, germinal center B cells, and also human B cell lines Ramos and Daudi. There is strain variability with respect to antigen distribution on thymocytes and Con A-activated spleen cells, with expression in BALB/c greater than that in C57BL/6. GL7 is commonly used as a marker for mouse germinal center B cells. The epitope of GL7 has been identified as a sialic acid glycan moiety called Neu5Ac. This moiety is recognized by CD22.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.25 µg/test
Aliases :
GL7 antigen; Ly77; Ly-77
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA