TCR V delta 4 Monoclonal Antibody (GL2), eFluor™ 660, eBioscience | Invitrogen 50-5702-80 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TCR V delta 4 Monoclonal Antibody (GL2), eFluor™ 660, eBioscience

catalog :

50-5702-80

quantity :

25 µg

price :

US 309.00

clonality :

monoclonal

host :

hamsters

conjugate :

efluor 660

clone name :

GL2

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 3c	Lebrero Fernández C, Bas Forsberg A. The ontogeny of Butyrophilin-like (Btnl) 1 and Btnl6 in murine small intestine. Sci Rep. 2016;6:31524 pubmed publisher
	Lebrero FernÃ¡ndez C, BergstrÃ¶m J, Pelaseyed T, Bas Forsberg A. Murine Butyrophilin-Like 1 and Btnl6 Form Heteromeric Complexes in Small Intestinal Epithelial Cells and Promote Proliferation of Local T Lymphocytes. Front Immunol. 2016;7:1 pubmed publisher
	Havran W, Jameson J. Epidermal T cells and wound healing. J Immunol. 2010;184:5423-8 pubmed publisher
	Boismenu R, Havran W. Modulation of epithelial cell growth by intraepithelial gamma delta T cells. Science. 1994;266:1253-5 pubmed
	Goodman T, Lefrancois L. Intraepithelial lymphocytes. Anatomical site, not T cell receptor form, dictates phenotype and function. J Exp Med. 1989;170:1569-81 pubmed

product information

Product Type :

Antibody

Product Name :

TCR V delta 4 Monoclonal Antibody (GL2), eFluor™ 660, eBioscience

Catalog # :

50-5702-80

Quantity :

25 µg

Price :

US 309.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Armenian Hamster

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.06 µg/test

Species :

Mouse

Clone :

GL2

Isotype :

IgG

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors. Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome. Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). The autoantibodies block TH1-mediated inflammatory autodestructive reactions and are believed to be a method by which the immune system compensates for disease. Most human T cells express the TCR alpha-beta and either CD4 or CD8 molecule (single positive, SP). A small number of T cells lack both CD4 and CD8 (double negative, DN). Increased percentages of alpha-beta DN T cells have been identified in some autoimmune and immunodeficiency disorders. Gamma-delta T cells are primarily found within the epithelium. They show less TCR diversity and recognize antigens differently than alpha-beta T cells. Subsets of gamma-delta T cells have shown antitumor and immunoregulatory activity.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.06 µg/test

Aliases :

TCR V delta4; TCRV delta 4; TCRV delta4; Vd4; Vdelta4

more info or order :

Invitrogen product webpage