product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
EOMES Monoclonal Antibody (Dan11mag), eFluor™ 660, eBioscience
catalog :
50-4875-82
quantity :
100 µg
price :
US 309.00
clonality :
monoclonal
host :
rat
conjugate :
efluor 660
clone name :
Dan11mag
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 38
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 4e
Bonilla W, Kirchhammer N, Marx A, Kallert S, Krzyzaniak M, Lu M, et al. Heterologous arenavirus vector prime-boost overrules self-tolerance for efficient tumor-specific CD8 T cell attack. Cell Rep Med. 2021;2:100209 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s4f
Benci J, Johnson L, Choa R, Xu Y, Qiu J, Zhou Z, et al. Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade. Cell. 2019;178:933-948.e14 pubmed publisher
Wiede F, Lu K, Du X, Zeissig M, Xu R, Goh P, et al. PTP1B Is an Intracellular Checkpoint that Limits T-cell and CAR T-cell Antitumor Immunity. Cancer Discov. 2022;12:752-773 pubmed publisher
Aschman T, Schaffer S, Biniaris Georgallis S, Triantafyllopoulou A, Staeheli P, Voll R. Interferon Lambda Regulates Cellular and Humoral Immunity in Pristane-Induced Lupus. Int J Mol Sci. 2021;22: pubmed publisher
Feizi N, Focaccetti C, Pacella I, Tucci G, Rossi A, Costanza M, et al. CD8+ T cells specific for cryptic apoptosis-associated epitopes exacerbate experimental autoimmune encephalomyelitis. Cell Death Dis. 2021;12:1026 pubmed publisher
Rashidieh B, Shohayeb B, Bain A, Fortuna P, Sinha D, Burgess A, et al. Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesis. PLoS Genet. 2021;17:e1009334 pubmed publisher
Klarquist J, Cross E, Thompson S, Willett B, Aldridge D, Caffrey Carr A, et al. B cells promote CD8 T cell primary and memory responses to subunit vaccines. Cell Rep. 2021;36:109591 pubmed publisher
Khuu M, Nallamothu T, Castro Rivera C, Arias Cavieres A, Szujewski C, Garcia Iii A. Stage-dependent effects of intermittent hypoxia influence the outcome of hippocampal adult neurogenesis. Sci Rep. 2021;11:6005 pubmed publisher
Braun S, Petrova R, Tang J, Krokhotin A, Miller E, Tang Y, et al. BAF subunit switching regulates chromatin accessibility to control cell cycle exit in the developing mammalian cortex. Genes Dev. 2021;35:335-353 pubmed publisher
Hu H, Song Z, Song G, Li S, Tu H, Wu M, et al. LPA signaling acts as a cell-extrinsic mechanism to initiate cilia disassembly and promote neurogenesis. Nat Commun. 2021;12:662 pubmed publisher
Wang H, Xiao Y, Su L, Cui N, Liu D. mTOR Modulates CD8+ T Cell Differentiation in Mice with Invasive Pulmonary Aspergillosis. Open Life Sci. 2018;13:129-136 pubmed publisher
Cole T, Chang Y, Dao K, Daza R, Hevner R, Costa L. Developmental exposure to diesel exhaust upregulates transcription factor expression, decreases hippocampal neurogenesis, and alters cortical lamina organization: relevance to neurodevelopmental disorders. J Neurodev Disord. 2020;12:41 pubmed publisher
Shohayeb B, Ho U, Hassan H, Piper M, Ng D. The Spindle-Associated Microcephaly Protein, WDR62, Is Required for Neurogenesis and Development of the Hippocampus. Front Cell Dev Biol. 2020;8:549353 pubmed publisher
Marinaik C, Kingstad Bakke B, Lee W, Hatta M, Sonsalla M, Larsen A, et al. Programming Multifaceted Pulmonary T Cell Immunity by Combination Adjuvants. Cell Rep Med. 2020;1:100095 pubmed publisher
Oda S, Anderson K, Ravikumar P, Bonson P, Garcia N, Jenkins C, et al. A Fas-4-1BB fusion protein converts a death to a pro-survival signal and enhances T cell therapy. J Exp Med. 2020;217: pubmed publisher
Shao W, Yang J, He M, Yu X, Lee C, Yang Z, et al. Centrosome anchoring regulates progenitor properties and cortical formation. Nature. 2020;580:106-112 pubmed publisher
Nelson B, Hodge R, Daza R, Tripathi P, Arnold S, Millen K, et al. Intermediate progenitors support migration of neural stem cells into dentate gyrus outer neurogenic niches. elife. 2020;9: pubmed publisher
Fregeac J, Moriceau S, Poli A, Nguyen L, Oury F, Colleaux L. Loss of the neurodevelopmental disease-associated gene miR-146a impairs neural progenitor differentiation and causes learning and memory deficits. Mol Autism. 2020;11:22 pubmed publisher
Panagiotakos G, Haveles C, Arjun A, Petrova R, Rana A, Portmann T, et al. Aberrant calcium channel splicing drives defects in cortical differentiation in Timothy syndrome. elife. 2019;8: pubmed publisher
S nchez Guardado L, Lois C. Lineage does not regulate the sensory synaptic input of projection neurons in the mouse olfactory bulb. elife. 2019;8: pubmed publisher
Istaces N, Splittgerber M, Lima Silva V, Nguyen M, Thomas S, Le A, et al. EOMES interacts with RUNX3 and BRG1 to promote innate memory cell formation through epigenetic reprogramming. Nat Commun. 2019;10:3306 pubmed publisher
Ponzetta A, Carriero R, Carnevale S, Barbagallo M, Molgora M, Perucchini C, et al. Neutrophils Driving Unconventional T Cells Mediate Resistance against Murine Sarcomas and Selected Human Tumors. Cell. 2019;178:346-360.e24 pubmed publisher
Roy A, Murphy R, Deng M, MacDonald J, Bammler T, Aldinger K, et al. PI3K-Yap activity drives cortical gyrification and hydrocephalus in mice. elife. 2019;8: pubmed publisher
Xu W, Cherrier D, Chea S, Vosshenrich C, Serafini N, Petit M, et al. An Id2RFP-Reporter Mouse Redefines Innate Lymphoid Cell Precursor Potentials. Immunity. 2019;50:1054-1068.e3 pubmed publisher
Rolot M, Dougall A, Chetty A, Javaux J, Chen T, Xiao X, et al. Helminth-induced IL-4 expands bystander memory CD8+ T cells for early control of viral infection. Nat Commun. 2018;9:4516 pubmed publisher
Wang H, Li J, Han Q, Yang F, Xiao Y, Xiao M, et al. IL-12 Influence mTOR to Modulate CD8+ T Cells Differentiation through T-bet and Eomesodermin in Response to Invasive Pulmonary Aspergillosis. Int J Med Sci. 2017;14:977-983 pubmed publisher
Haushalter C, Schuhbaur B, Dolle P, Rhinn M. Meningeal retinoic acid contributes to neocortical lamination and radial migration during mouse brain development. Biol Open. 2017;6:148-160 pubmed publisher
Benci J, Xu B, Qiu Y, Wu T, Dada H, Twyman Saint Victor C, et al. Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade. Cell. 2016;167:1540-1554.e12 pubmed publisher
Dendrou C, Cortes A, Shipman L, Evans H, Attfield K, Jostins L, et al. Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity. Sci Transl Med. 2016;8:363ra149 pubmed
Fame R, MacDonald J, Dunwoodie S, Takahashi E, Macklis J. Cited2 Regulates Neocortical Layer II/III Generation and Somatosensory Callosal Projection Neuron Development and Connectivity. J Neurosci. 2016;36:6403-19 pubmed publisher
Takeo Y, Kurabayashi N, Nguyen M, Sanada K. The G protein-coupled receptor GPR157 regulates neuronal differentiation of radial glial progenitors through the Gq-IP3 pathway. Sci Rep. 2016;6:25180 pubmed publisher
Lin C, Erkek S, Tong Y, Yin L, Federation A, Zapatka M, et al. Active medulloblastoma enhancers reveal subgroup-specific cellular origins. Nature. 2016;530:57-62 pubmed publisher
Ngiow S, Young A, Jacquelot N, Yamazaki T, Enot D, Zitvogel L, et al. A Threshold Level of Intratumor CD8+ T-cell PD1 Expression Dictates Therapeutic Response to Anti-PD1. Cancer Res. 2015;75:3800-11 pubmed publisher
Martinet V, Tonon S, Torres D, Azouz A, Nguyen M, Kohler A, et al. Type I interferons regulate eomesodermin expression and the development of unconventional memory CD8(+) T cells. Nat Commun. 2015;6:7089 pubmed publisher
Mizuguchi R, Naritsuka H, Mori K, Mao C, Klein W, Yoshihara Y. Tbr2 deficiency in mitral and tufted cells disrupts excitatory-inhibitory balance of neural circuitry in the mouse olfactory bulb. J Neurosci. 2012;32:8831-44 pubmed publisher
Qui H, Hagymasi A, Bandyopadhyay S, St Rose M, Ramanarasimhaiah R, Menoret A, et al. CD134 plus CD137 dual costimulation induces Eomesodermin in CD4 T cells to program cytotoxic Th1 differentiation. J Immunol. 2011;187:3555-64 pubmed publisher
Weinreich M, Odumade O, Jameson S, Hogquist K. T cells expressing the transcription factor PLZF regulate the development of memory-like CD8+ T cells. Nat Immunol. 2010;11:709-16 pubmed publisher
Marshall H, Prince A, Berg L, Welsh R. IFN-alpha beta and self-MHC divert CD8 T cells into a distinct differentiation pathway characterized by rapid acquisition of effector functions. J Immunol. 2010;185:1419-28 pubmed publisher
product information
Product Type :
Antibody
Product Name :
EOMES Monoclonal Antibody (Dan11mag), eFluor™ 660, eBioscience
Catalog # :
50-4875-82
Quantity :
100 µg
Price :
US 309.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.25 µg/test
Species :
Mouse
Clone :
Dan11mag
Isotype :
IgG2a, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
TBR2 is a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similiar protein disrupted in mice is shown to be essential during trophoblast development and gastrulation. TBR2 plays a role in brain development and is required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.25 µg/test
Aliases :
C77258; EOMES; eomesodermin; eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; T-box transcription factor; TBR2; TBR-2; T-brain-2
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA