This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
F4/80 Monoclonal Antibody (BM8), eFluor 660, eBioscience™
catalog :
50-4801-80
quantity :
25µg
price :
US 126
clonality :
monoclonal
host :
rat
conjugate :
efluor 660
clone name :
BM8
reactivity :
mouse
application :
flow cytometry
citations: 166
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; fig 3
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Beneke V, Küster F, Neehus A, Hesse C, Lopez Rodriguez E, Haake K, et al. An immune cell spray (ICS) formulation allows for the delivery of functional monocyte/macrophages. Sci Rep. 2018;8:16281 pubmed publisher
Waterborg C, Koenders M, van Lent P, van der Kraan P, van de Loo F. Tyro3/Axl/Mertk-deficient mice develop bone marrow edema which is an early pathological marker in rheumatoid arthritis. PLoS ONE. 2018;13:e0205902 pubmed publisher
Kim H, Tan Y, Ma W, Merkurjev D, Destici E, Ma Q, et al. Pluripotency factors functionally premark cell-type-restricted enhancers in ES cells. Nature. 2018;556:510-514 pubmed publisher
Lee C, Lee W, Cho S, Park S. Characterization of Multiple Cytokine Combinations and TGF-? on Differentiation and Functions of Myeloid-Derived Suppressor Cells. Int J Mol Sci. 2018;19: pubmed publisher
Li Z, Gothard E, Coles M, Ambler C. Quantitative Methods for Measuring Repair Rates and Innate-Immune Cell Responses in Wounded Mouse Skin. Front Immunol. 2018;9:347 pubmed publisher
Barnette D, Cahill T, Gunadasa Rohling M, Carr C, Freeman M, Riley P. iRhom2-mediated proinflammatory signalling regulates heart repair following myocardial infarction. JCI Insight. 2018;3: pubmed publisher
Mogami H, Kishore A, Word R. Collagen Type 1 Accelerates Healing of Ruptured Fetal Membranes. Sci Rep. 2018;8:696 pubmed publisher
Bandla H, Dasgupta D, Mauer A, Nozickova B, Kumar S, Hirsova P, et al. Deletion of endoplasmic reticulum stress-responsive co-chaperone p58IPK protects mice from diet-induced steatohepatitis. Hepatol Res. 2018;48:479-494 pubmed publisher
Nguyen Thanh T, Kim D, Lee S, Kim W, Park S, Kang K. Inhibition of histone deacetylase 1 ameliorates renal tubulointerstitial fibrosis via modulation of inflammation and extracellular matrix gene transcription in mice. Int J Mol Med. 2018;41:95-106 pubmed publisher
Chang C, Lu C, Lin C, Martel J, Ko Y, Ojcius D, et al. Antrodia cinnamomea reduces obesity and modulates the gut microbiota in high-fat diet-fed mice. Int J Obes (Lond). 2018;42:231-243 pubmed publisher
Bai W, Li C, Zhang C, Xu L, Zeng Q, Hu B, et al. Prolonged Deleterious Influences of Chemotherapeutic Agent CPT-11 on Resident Peritoneal Macrophages and B1 Cells. Front Immunol. 2017;8:1919 pubmed publisher
von Klitzing E, Ekmekciu I, Bereswill S, Heimesaat M. Intestinal and Systemic Immune Responses upon Multi-drug Resistant Pseudomonas aeruginosa Colonization of Mice Harboring a Human Gut Microbiota. Front Microbiol. 2017;8:2590 pubmed publisher
Rutkowska A, Sailer A, Dev K. EBI2 receptor regulates myelin development and inhibits LPC-induced demyelination. J Neuroinflammation. 2017;14:250 pubmed publisher
Ge F, Zhu S, Liu L, Yan J, Ji Y, Sun Z. Anti-inflammatory effects of Fagopyrum cymosum administered as a potential drug for ulcerative colitis. Exp Ther Med. 2017;14:4745-4754 pubmed publisher
Grunau A, Escher U, Kuhl A, Bereswill S, Heimesaat M. Toll-like receptor-4 differentially mediates intestinal and extra-intestinal immune responses upon multi-drug resistant Pseudomonas aeruginosa association of IL10-/- mice with chronic colitis. Gut Pathog. 2017;9:61 pubmed publisher
Zhu D, Tan J, Maleken A, Muljadi R, Chan S, Lau S, et al. Human amnion cells reverse acute and chronic pulmonary damage in experimental neonatal lung injury. Stem Cell Res Ther. 2017;8:257 pubmed publisher
Shim D, Shin W, Yu S, Kim B, Ye S, Koppula S, et al. BOT-4-one attenuates NLRP3 inflammasome activation: NLRP3 alkylation leading to the regulation of its ATPase activity and ubiquitination. Sci Rep. 2017;7:15020 pubmed publisher
Esposito R, Morello S, Vllahu M, Eletto D, Porta A, Tosco A. Gastric TFF1 Expression from Acute to Chronic Helicobacter Infection. Front Cell Infect Microbiol. 2017;7:434 pubmed publisher
Li Y, Lv M, Su C, Long S, Zhang W, Conway K, et al. p40 phox -Deficient Mice Exhibit Impaired Bacterial Clearance and Enhanced Pro-inflammatory Responses during Salmonella enterica serovar Typhimurium Infection. Front Immunol. 2017;8:1270 pubmed publisher
Llorente C, Jepsen P, Inamine T, Wang L, Bluemel S, Wang H, et al. Gastric acid suppression promotes alcoholic liver disease by inducing overgrowth of intestinal Enterococcus. Nat Commun. 2017;8:837 pubmed publisher
Grunau A, Escher U, Bereswill S, Heimesaat M. Toll-Like Receptor-4 Dependent Inflammatory Responses Following Intestinal Colonization of Secondary Abiotic IL10-Deficient Mice with Multidrug-Resistant Pseudomonas Aeruginosa. Eur J Microbiol Immunol (Bp). 2017;7:210-219 pubmed publisher
von Klitzing E, Bereswill S, Heimesaat M. Multidrug-Resistant Pseudomonas Aeruginosa Induce Systemic Pro-Inflammatory Immune Responses in Colonized Mice. Eur J Microbiol Immunol (Bp). 2017;7:200-209 pubmed publisher
Mogami H, Hari Kishore A, Akgul Y, Word R. Healing of Preterm Ruptured Fetal Membranes. Sci Rep. 2017;7:13139 pubmed publisher
Zhou D, Qin J, Huang J, Wang F, Xu G, Lv Y, et al. Zoledronic acid inhibits infiltration of tumor-associated macrophages and angiogenesis following transcatheter arterial chemoembolization in rat hepatocellular carcinoma models. Oncol Lett. 2017;14:4078-4084 pubmed publisher
Komine S, Akiyama K, Warabi E, Oh S, Kuga K, Ishige K, et al. Exercise training enhances in vivo clearance of endotoxin and attenuates inflammatory responses by potentiating Kupffer cell phagocytosis. Sci Rep. 2017;7:11977 pubmed publisher
Ogura M, Bridgeman V, Malanchi I. Macrophages unlock progression of breast cancer cells experiencing matrigel-segregation in transplantation models. Sci Rep. 2017;7:11028 pubmed publisher
Nakanishi H, Kawashima Y, Kurima K, Chae J, Ross A, Pinto Patarroyo G, et al. NLRP3 mutation and cochlear autoinflammation cause syndromic and nonsyndromic hearing loss DFNA34 responsive to anakinra therapy. Proc Natl Acad Sci U S A. 2017;114:E7766-E7775 pubmed publisher
Shintani Y, Ito T, Fields L, Shiraishi M, Ichihara Y, Sato N, et al. IL-4 as a Repurposed Biological Drug for Myocardial Infarction through Augmentation of Reparative Cardiac Macrophages: Proof-of-Concept Data in Mice. Sci Rep. 2017;7:6877 pubmed publisher
Zhu Y, Zhang L, Lu Q, Gao Y, Cai Y, Sui A, et al. Identification of different macrophage subpopulations with distinct activities in a mouse model of oxygen-induced retinopathy. Int J Mol Med. 2017;40:281-292 pubmed publisher
Young C, Rorke E, Adhikary G, Xu W, Eckert R. Loss of epidermal AP1 transcription factor function reduces filaggrin level, alters chemokine expression and produces an ichthyosis-related phenotype. Cell Death Dis. 2017;8:e2840 pubmed publisher
Yang A, Inamine T, Hochrath K, Chen P, Wang L, Llorente C, et al. Intestinal fungi contribute to development of alcoholic liver disease. J Clin Invest. 2017;127:2829-2841 pubmed publisher
Park D, Lee J, Kim J, Kim K, Hong S, Han S, et al. Plastic roles of pericytes in the blood-retinal barrier. Nat Commun. 2017;8:15296 pubmed publisher
Simkin J, Gawriluk T, Gensel J, Seifert A. Macrophages are necessary for epimorphic regeneration in African spiny mice. elife. 2017;6: pubmed publisher
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Ku A, Shaver T, Rao A, Howard J, Rodriguez C, Miao Q, et al. TCF7L1 promotes skin tumorigenesis independently of β-catenin through induction of LCN2. elife. 2017;6: pubmed publisher
Reißig S, Tang Y, Nikolaev A, Gerlach K, Wolf C, Davari K, et al. Elevated levels of Bcl-3 inhibits Treg development and function resulting in spontaneous colitis. Nat Commun. 2017;8:15069 pubmed publisher
Friesen M, Camahort R, Lee Y, Xia F, Gerszten R, Rhee E, et al. Activation of IRF1 in Human Adipocytes Leads to Phenotypes Associated with Metabolic Disease. Stem Cell Reports. 2017;8:1164-1173 pubmed publisher
Ekmekciu I, Fiebiger U, Stingl K, Bereswill S, Heimesaat M. Amelioration of intestinal and systemic sequelae of murine Campylobacter jejuni infection by probiotic VSL#3 treatment. Gut Pathog. 2017;9:17 pubmed publisher
Jatana S, Palmer B, Phelan S, Gelein R, Delouise L. In vivo quantification of quantum dot systemic transport in C57BL/6 hairless mice following skin application post-ultraviolet radiation. Part Fibre Toxicol. 2017;14:12 pubmed publisher
Cho H, Kim J, Jang H, Lee T, Jung M, Kim T, et al. Alpha-lipoic acid ameliorates the epithelial mesenchymal transition induced by unilateral ureteral obstruction in mice. Sci Rep. 2017;7:46065 pubmed publisher
Zhu H, Lou F, Yin Q, Gao Y, Sun Y, Bai J, et al. RIG-I antiviral signaling drives interleukin-23 production and psoriasis-like skin disease. EMBO Mol Med. 2017;9:589-604 pubmed publisher
Long Y, Zhen X, Zhu F, Hu Z, Lei W, Li S, et al. Hyperhomocysteinemia Exacerbates Cisplatin-induced Acute Kidney Injury. Int J Biol Sci. 2017;13:219-231 pubmed publisher
Garcia Valtanen P, Guzman Genuino R, Williams D, Hayball J, Diener K. Evaluation of trained immunity by ?-1, 3 (d)-glucan on murine monocytes in vitro and duration of response in vivo. Immunol Cell Biol. 2017;95:601-610 pubmed publisher
Piao Z, Yuan H, Wang C, Shi L. IRF3 Inhibits Neutrophil Recruitment in Mice Infected with Pseudomonas aeruginosa. Inflammation. 2017;40:735-744 pubmed publisher
Berlato C, Khan M, Schioppa T, Thompson R, Maniati E, Montfort A, et al. A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer. J Clin Invest. 2017;127:801-813 pubmed publisher
Liu J, Xue Y, Dong D, Xiao C, Lin C, Wang H, et al. CCR2- and CCR2+ corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion. Mucosal Immunol. 2017;10:1145-1159 pubmed publisher
Deguise M, De Repentigny Y, McFall E, Auclair N, Sad S, Kothary R. Immune dysregulation may contribute to disease pathogenesis in spinal muscular atrophy mice. Hum Mol Genet. 2017;26:801-819 pubmed publisher
Zhang Y, Zhang Y, Li X, Zhang M, Lv K. Microarray analysis of circular RNA expression patterns in polarized macrophages. Int J Mol Med. 2017;39:373-379 pubmed publisher
Dill R, Walker A. Role of Prolactin in Promotion of Immune Cell Migration into the Mammary Gland. J Mammary Gland Biol Neoplasia. 2017;22:13-26 pubmed publisher
Ben Shoshan S, Kagan P, Sultan M, Barabash Z, Dor C, Jacob Hirsch J, et al. ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis. RNA Biol. 2017;14:587-602 pubmed publisher
Wei W, Bastiaansen Jenniskens Y, Suijkerbuijk M, Kops N, Bos P, Verhaar J, et al. High fat diet accelerates cartilage repair in DBA/1 mice. J Orthop Res. 2017;35:1258-1264 pubmed publisher
Owusu Boaitey N, Bauckman K, Zhang T, Mysorekar I. Macrophagic control of the response to uropathogenic E. coli infection by regulation of iron retention in an IL-6-dependent manner. Immun Inflamm Dis. 2016;4:413-426 pubmed
Sakata K, Araki K, Nakano H, Nishina T, Komazawa Sakon S, Murai S, et al. Novel method to rescue a lethal phenotype through integration of target gene onto the X-chromosome. Sci Rep. 2016;6:37200 pubmed publisher
Barnett F, Rosenfeld M, Wood M, Kiosses W, Usui Y, Marchetti V, et al. Macrophages form functional vascular mimicry channels in vivo. Sci Rep. 2016;6:36659 pubmed publisher
Cousins F, Kirkwood P, Saunders P, Gibson D. Evidence for a dynamic role for mononuclear phagocytes during endometrial repair and remodelling. Sci Rep. 2016;6:36748 pubmed publisher
Sassmann Schweda A, Singh P, Tang C, Wietelmann A, Wettschureck N, Offermanns S. Increased apoptosis and browning of TAK1-deficient adipocytes protects against obesity. JCI Insight. 2016;1:e81175 pubmed publisher
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Li C, Srivastava R, Weng Z, Croutch C, Agarwal A, Elmets C, et al. Molecular Mechanism Underlying Pathogenesis of Lewisite-Induced Cutaneous Blistering and Inflammation: Chemical Chaperones as Potential Novel Antidotes. Am J Pathol. 2016;186:2637-49 pubmed publisher
Mucci A, Kunkiel J, Suzuki T, Brennig S, Glage S, Kühnel M, et al. Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency. Stem Cell Reports. 2016;7:292-305 pubmed publisher
Liu L, Jin X, Zhou Z, Shen C. Enhancement of Anti-Hypoxic Activity and Differentiation of Cardiac Stem Cells by Supernatant Fluids from Cultured Macrophages that Phagocytized Dead Mesenchymal Stem Cells. Int J Mol Sci. 2016;17: pubmed publisher
Heimesaat M, Alutis M, Grundmann U, Fischer A, Göbel U, Bereswill S. The Role of IL-23, IL-22, and IL-18 in Campylobacter Jejuni Infection of Conventional Infant Mice. Eur J Microbiol Immunol (Bp). 2016;6:124-36 pubmed publisher
Heimesaat M, Grundmann U, Alutis M, Fischer A, Göbel U, Bereswill S. The IL-23/IL-22/IL-18 axis in murine Campylobacter jejuni infection. Gut Pathog. 2016;8:21 pubmed publisher
Di Scala M, Gil Fariña I, Olagüe C, Vales A, Sobrevals L, Fortes P, et al. Identification of IFN-γ-producing T cells as the main mediators of the side effects associated to mouse interleukin-15 sustained exposure. Oncotarget. 2016;7:49008-49026 pubmed publisher
Dou G, Li N, Chang T, Zhang P, Gao X, Yan X, et al. Myeloid-Specific Blockade of Notch Signaling Attenuates Choroidal Neovascularization through Compromised Macrophage Infiltration and Polarization in Mice. Sci Rep. 2016;6:28617 pubmed publisher
Ochi T, Feng Y, Kitamoto S, Nagao Kitamoto H, Kuffa P, Atarashi K, et al. Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine. Sci Rep. 2016;6:27634 pubmed publisher
Xu Y, Liu Y, Yang C, Kang L, Wang M, Hu J, et al. Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses. Immunology. 2016;149:157-71 pubmed publisher
Tian Y, Kuo C, Akbari O, Ou J. Maternal-Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission. Immunity. 2016;44:1204-14 pubmed publisher
Yao Y, Norris E, Mason C, Strickland S. Laminin regulates PDGFR?(+) cell stemness and muscle development. Nat Commun. 2016;7:11415 pubmed publisher
Miura K, Ishioka M, Minami S, Horie Y, Ohshima S, Goto T, et al. Toll-like Receptor 4 on Macrophage Promotes the Development of Steatohepatitis-related Hepatocellular Carcinoma in Mice. J Biol Chem. 2016;291:11504-17 pubmed publisher
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Liu S, Wu C, Huang K, Wang C, Guan S, Chen L, et al. C/EBP homologous protein (CHOP) deficiency ameliorates renal fibrosis in unilateral ureteral obstructive kidney disease. Oncotarget. 2016;7:21900-12 pubmed publisher
Gaide Chevronnay H, Janssens V, Van Der Smissen P, Rocca C, Liao X, Refetoff S, et al. Hematopoietic Stem Cells Transplantation Can Normalize Thyroid Function in a Cystinosis Mouse Model. Endocrinology. 2016;157:1363-71 pubmed publisher
Chu C, Gardner P, Copland D, Liyanage S, Gonzalez Cordero A, Kleine Holthaus S, et al. Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model. Dis Model Mech. 2016;9:473-81 pubmed publisher
Heimesaat M, Karadas G, Fischer A, Göbel U, Alter T, Bereswill S, et al. Toll-Like Receptor-4 Dependent Small Intestinal Immune Responses Following Murine Arcobacter Butzleri Infection. Eur J Microbiol Immunol (Bp). 2015;5:333-42 pubmed publisher
Gölz G, Karadas G, Fischer A, Göbel U, Alter T, Bereswill S, et al. Toll-Like Receptor-4 is Essential for Arcobacter Butzleri-Induced Colonic and Systemic Immune Responses in Gnotobiotic IL-10(-/-) Mice. Eur J Microbiol Immunol (Bp). 2015;5:321-32 pubmed publisher
Alutis M, Grundmann U, Fischer A, Hagen U, Kühl A, Göbel U, et al. The Role of Gelatinases in Campylobacter Jejuni Infection of Gnotobiotic Mice. Eur J Microbiol Immunol (Bp). 2015;5:256-67 pubmed publisher
Lee K, Spata M, Bayne L, Buza E, Durham A, Allman D, et al. Hif1a Deletion Reveals Pro-Neoplastic Function of B Cells in Pancreatic Neoplasia. Cancer Discov. 2016;6:256-69 pubmed publisher
Wu L, Li N, Zhang M, Xue S, Cassady K, Lin Q, et al. MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice. Proc Natl Acad Sci U S A. 2015;112:15994-9 pubmed publisher
Shawber C, Lin L, Gnarra M, Sauer M, Papaioannou V, KITAJEWSKI J, et al. Vascular Notch proteins and Notch signaling in the peri-implantation mouse uterus. Vasc Cell. 2015;7:9 pubmed publisher
Rocca C, Kreymerman A, Ur S, Frizzi K, Naphade S, Lau A, et al. Treatment of Inherited Eye Defects by Systemic Hematopoietic Stem Cell Transplantation. Invest Ophthalmol Vis Sci. 2015;56:7214-23 pubmed publisher
Kraut B, Maier H, Kókai E, Fiedler K, Boettger T, Illing A, et al. Cardiac-Specific Activation of IKK2 Leads to Defects in Heart Development and Embryonic Lethality. PLoS ONE. 2015;10:e0141591 pubmed publisher
Freedman T, Tan Y, Skrzypczynska K, Manz B, Sjaastad F, Goodridge H, et al. LynA regulates an inflammation-sensitive signaling checkpoint in macrophages. elife. 2015;4: pubmed publisher
Le Roux I, Konge J, Le Cam L, Flamant P, Tajbakhsh S. Numb is required to prevent p53-dependent senescence following skeletal muscle injury. Nat Commun. 2015;6:8528 pubmed publisher
Heimesaat M, Fischer A, Kühl A, Göbel U, Gozes I, Bereswill S. Anti-Inflammatory Properties of NAP in Acute Toxoplasma Gondii-Induced Ileitis in Mice. Eur J Microbiol Immunol (Bp). 2015;5:210-20 pubmed publisher
Heimesaat M, Karadas G, Alutis M, Fischer A, Kühl A, Breithaupt A, et al. Survey of small intestinal and systemic immune responses following murine Arcobacter butzleri infection. Gut Pathog. 2015;7:28 pubmed publisher
Ying W, Tseng A, Chang R, Morin A, Brehm T, Triff K, et al. MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation. J Clin Invest. 2015;125:4149-59 pubmed publisher
Das S, Rachagani S, Sheinin Y, Smith L, Gurumurthy C, Roy H, et al. Mice deficient in Muc4 are resistant to experimental colitis and colitis-associated colorectal cancer. Oncogene. 2016;35:2645-54 pubmed publisher
Waddell A, Vallance J, Moore P, Hummel A, Wu D, Shanmukhappa S, et al. IL-33 Signaling Protects from Murine Oxazolone Colitis by Supporting Intestinal Epithelial Function. Inflamm Bowel Dis. 2015;21:2737-46 pubmed publisher
Schoiswohl G, Stefanovic Racic M, Menke M, Wills R, Surlow B, Basantani M, et al. Impact of Reduced ATGL-Mediated Adipocyte Lipolysis on Obesity-Associated Insulin Resistance and Inflammation in Male Mice. Endocrinology. 2015;156:3610-24 pubmed publisher
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Vogel A, Brown D. Single-Dose CpG Immunization Protects Against a Heterosubtypic Challenge and Generates Antigen-Specific Memory T Cells. Front Immunol. 2015;6:327 pubmed publisher
Jin X, Yao T, Zhou Z, Zhu J, Zhang S, Hu W, et al. Advanced Glycation End Products Enhance Macrophages Polarization into M1 Phenotype through Activating RAGE/NF-κB Pathway. Biomed Res Int. 2015;2015:732450 pubmed publisher
Keswani R, Yoon G, Sud S, Stringer K, Rosania G. A far-red fluorescent probe for flow cytometry and image-based functional studies of xenobiotic sequestering macrophages. Cytometry A. 2015;87:855-67 pubmed publisher
Tähtinen S, Kaikkonen S, Merisalo Soikkeli M, Grönberg Vähä Koskela S, Kanerva A, Parviainen S, et al. Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors. PLoS ONE. 2015;10:e0131242 pubmed publisher
Singh N, Kotla S, Dyukova E, Traylor J, Orr A, Chernoff J, et al. Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice. Nat Commun. 2015;6:7450 pubmed publisher
Khan I, Perrard X, Brunner G, Lui H, Sparks L, Smith S, et al. Intermuscular and perimuscular fat expansion in obesity correlates with skeletal muscle T cell and macrophage infiltration and insulin resistance. Int J Obes (Lond). 2015;39:1607-18 pubmed publisher
Williams B, Tebbutt N, Buchert M, Putoczki T, Doggett K, Bao S, et al. Glycoprotein A33 deficiency: a new mouse model of impaired intestinal epithelial barrier function and inflammatory disease. Dis Model Mech. 2015;8:805-15 pubmed publisher
Erny D, HrabÄ› de Angelis A, Jaitin D, Wieghofer P, Staszewski O, David E, et al. Host microbiota constantly control maturation and function of microglia in the CNS. Nat Neurosci. 2015;18:965-77 pubmed publisher
Shankman L, Gomez D, Cherepanova O, Salmon M, Alencar G, Haskins R, et al. KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis. Nat Med. 2015;21:628-37 pubmed publisher
Deng Z, Ma S, Zhou H, Zang A, Fang Y, Li T, et al. Tyrosine phosphatase SHP-2 mediates C-type lectin receptor-induced activation of the kinase Syk and anti-fungal TH17 responses. Nat Immunol. 2015;16:642-52 pubmed publisher
Mazumdar S, Arendt L, Phillips S, Sedic M, Kuperwasser C, Gill G. CoREST1 promotes tumor formation and tumor stroma interactions in a mouse model of breast cancer. PLoS ONE. 2015;10:e0121281 pubmed publisher
Neng L, Zhang J, Yang J, Zhang F, Lopez I, Dong M, et al. Structural changes in thestrial blood-labyrinth barrier of aged C57BL/6 mice. Cell Tissue Res. 2015;361:685-96 pubmed publisher
Morris M, Beare J, Reed R, Dale J, LeBlanc A, Kaufman C, et al. Systemically delivered adipose stromal vascular fraction cells disseminate to peripheral artery walls and reduce vasomotor tone through a CD11b+ cell-dependent mechanism. Stem Cells Transl Med. 2015;4:369-80 pubmed publisher
Alutis M, Grundmann U, Fischer A, Kühl A, Bereswill S, Heimesaat M. Selective gelatinase inhibition reduces apoptosis and pro-inflammatory immune cell responses in Campylobacter jejuni-infected gnotobiotic IL-10 deficient mice. Eur J Microbiol Immunol (Bp). 2014;4:213-22 pubmed publisher
Castellana D, Paus R, Perez Moreno M. Macrophages contribute to the cyclic activation of adult hair follicle stem cells. PLoS Biol. 2014;12:e1002002 pubmed publisher
Huang H, Koelle P, Fendler M, Schroettle A, Czihal M, Hoffmann U, et al. Niacin reverses migratory macrophage foam cell arrest mediated by oxLDL in vitro. PLoS ONE. 2014;9:e114643 pubmed publisher
Anderson E, Kwee B, Lewin S, Raimondo T, Mehta M, Mooney D. Local delivery of VEGF and SDF enhances endothelial progenitor cell recruitment and resultant recovery from ischemia. Tissue Eng Part A. 2015;21:1217-27 pubmed publisher
Dabydeen S, Kang K, Díaz Cruz E, Alamri A, Axelrod M, Bouker K, et al. Comparison of tamoxifen and letrozole response in mammary preneoplasia of ER and aromatase overexpressing mice defines an immune-associated gene signature linked to tamoxifen resistance. Carcinogenesis. 2015;36:122-32 pubmed publisher
Baptista A, Roozendaal R, Reijmers R, Koning J, Unger W, Greuter M, et al. Lymph node stromal cells constrain immunity via MHC class II self-antigen presentation. elife. 2014;3: pubmed publisher
Habbeddine M, Verbeke P, Karaz S, Bobé P, Kanellopoulos Langevin C. Leukocyte population dynamics and detection of IL-9 as a major cytokine at the mouse fetal-maternal interface. PLoS ONE. 2014;9:e107267 pubmed publisher
Lanaya H, Natarajan A, Komposch K, Li L, Amberg N, Chen L, et al. EGFR has a tumour-promoting role in liver macrophages during hepatocellular carcinoma formation. Nat Cell Biol. 2014;16:972-7 pubmed publisher
Zhou H, Yan H, Pan H, Hou K, Akk A, Springer L, et al. Peptide-siRNA nanocomplexes targeting NF-κB subunit p65 suppress nascent experimental arthritis. J Clin Invest. 2014;124:4363-74 pubmed publisher
Heimesaat M, Dunay I, Alutis M, Fischer A, Möhle L, Göbel U, et al. Nucleotide-oligomerization-domain-2 affects commensal gut microbiota composition and intracerebral immunopathology in acute Toxoplasma gondii induced murine ileitis. PLoS ONE. 2014;9:e105120 pubmed publisher
Criscimanna A, Coudriet G, Gittes G, Piganelli J, Esni F. Activated macrophages create lineage-specific microenvironments for pancreatic acinar- and ?-cell regeneration in mice. Gastroenterology. 2014;147:1106-18.e11 pubmed publisher
Hernández E, Lee S, Kim J, Duran A, Linares J, Yajima T, et al. A macrophage NBR1-MEKK3 complex triggers JNK-mediated adipose tissue inflammation in obesity. Cell Metab. 2014;20:499-511 pubmed publisher
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product information
Product Type :
Antibody
Product Name :
F4/80 Monoclonal Antibody (BM8), eFluor 660, eBioscience™
Catalog # :
50-4801-80
Quantity :
25µg
Price :
US 126
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 1 µg/test
Species :
Mouse
Clone :
BM8
Isotype :
IgG2a, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
F4/80 antigen is a 160 kDa cell surface glycoprotein that is a member of the EGF TM7 family of proteins and shares 68% overall amino acid identity with human EGF module containing mucin like hormone receptor 1 (EMR1). Expression of F4/80 is heterogeneous and is reported to vary during macrophage maturation and activation. The F4/80 antigen is expressed on a wide range of mature tissue macrophages including Kupffer cells, Langerhans, microglia, macrophages located in the gut lamina propria, peritoneal cavity, lung, thymus, bone marrow stroma and macrophages in the red pulp of the spleen. F4/80 expression has also been reported on a subpopulation of dendritic cells but is absent from macrophages located in T cell areas of the spleen and lymph node. The ligands and biological functions of the F4/80 antigen have not yet been determined but recent studies suggest a role for F4/80 in the generation of efferent CD8+ve regulatory T cells.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1 µg/test
Aliases :
DD7A5-7; EGF-TM7; F4/80; Gpf480; Ly71; TM7LN3; F480
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA