CD307e (FcRL5) Monoclonal Antibody (509F6), eFluor™ 660, eBioscience | Invitrogen 50-3078-42 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD307e (FcRL5) Monoclonal Antibody (509F6), eFluor™ 660, eBioscience

catalog :

50-3078-42

quantity :

100 Tests

price :

US 383

clonality :

monoclonal

host :

mouse

conjugate :

efluor 660

clone name :

509f6

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...	Rodda L, Netland J, Shehata L, Pruner K, Morawski P, Thouvenel C, et al. Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19. Cell. 2021;184:169-183.e17 pubmed publisher
flow cytometry; human; 1:200; loading ...; fig 2c	Zumaquero E, Stone S, Scharer C, Jenks S, Nellore A, Mousseau B, et al. IFNγ induces epigenetic programming of human T-bethi B cells and promotes TLR7/8 and IL-21 induced differentiation. elife. 2019;8: pubmed publisher
	Elkins K, Zheng B, Go M, Slaga D, Du C, Scales S, et al. FcRL5 as a target of antibody-drug conjugates for the treatment of multiple myeloma. Mol Cancer Ther. 2012;11:2222-32 pubmed publisher
	Wilson T, Fuchs A, Colonna M. Cutting edge: human FcRL4 and FcRL5 are receptors for IgA and IgG. J Immunol. 2012;188:4741-5 pubmed publisher
	Haga C, Ehrhardt G, Boohaker R, Davis R, Cooper M. Fc receptor-like 5 inhibits B cell activation via SHP-1 tyrosine phosphatase recruitment. Proc Natl Acad Sci U S A. 2007;104:9770-5 pubmed
	Ise T, Nagata S, Kreitman R, Wilson W, Wayne A, Stetler Stevenson M, et al. Elevation of soluble CD307 (IRTA2/FcRH5) protein in the blood and expression on malignant cells of patients with multiple myeloma, chronic lymphocytic leukemia, and mantle cell lymphoma. Leukemia. 2007;21:169-74 pubmed
	Hatzivassiliou G, Miller I, Takizawa J, Palanisamy N, Rao P, Iida S, et al. IRTA1 and IRTA2, novel immunoglobulin superfamily receptors expressed in B cells and involved in chromosome 1q21 abnormalities in B cell malignancy. Immunity. 2001;14:277-89 pubmed

product information

Product Type :

Antibody

Product Name :

CD307e (FcRL5) Monoclonal Antibody (509F6), eFluor™ 660, eBioscience

Catalog # :

50-3078-42

Quantity :

100 Tests

Pricing :

US 383

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 µL (1 µg)/test

Species :

Human

Clone :

509F6

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

Fc receptor homologs (FcRH5), also known as IRTA2 proteins, are transmembrane proteins with sequence homology to classical Fc receptor families. FcRH5 function as activating or inhibitory receptors on discrete B cell populations and are involved in B-cell development and differentiation in peripheral lymphoid organs. FcRH5 expression is deregulated in multiple myeloma and Burkitt lymphoma cell lines with 1q21 abnormalities. FcRH5 may play a critical role for the pathogenesis of B-cell lymphoma.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL (1 µg)/test

Aliases :

BXMAS1; BXMAS1-like protein 2; CD307; CD307e; fc receptor homolog 3; Fc receptor homolog 5; Fc receptor like 5; Fc receptor-like 3; Fc receptor-like 5; Fc receptor-like protein 3; Fc receptor-like protein 5; Fcrh3; FCRH5; Fcrl3; Fcrl5; FcR-like protein 5; Immune receptor translocation-associated protein 2; immunoglobulin superfamily receptor translocation associated 2 (IRTA2); IRTA2; mBXMH2; moFcRH3; PRO820; rCG62831-like; UNQ503/PRO820

more info or order :

Invitrogen product webpage